Meta-analysis of archived DNA microarrays identifies genes regulated by hypoxia and involved in a metastatic phenotype in cancer cells von Pierre, Michael, DeHertogh, Benoît, Gaigneaux, Anthoula, DeMeulder, Bertrand, Berger, Fabrice, Bareke, Eric, Michiels, Carine, Depiereux, Eric

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Enhanced Meta-analysis Highlights Genes Involved in Metastasis from Several Microarray Datasets von Pierre, Michael

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TMC647055, a Potent Nonnucleoside Hepatitis C Virus NS5B Polymerase Inhibitor with Cross-Genotypic Coverage von DEVOGELAERE, Benoit, BERKE, Jan Martin, LENZ, Oliver, CUMMINGS, Maxwell D, CLAYTON, Reginald F, VENDEVILLE, Sandrine, RABOISSON, Pierre, SIMMEN, Kenneth A, FANNING, Gregory C, LIN, Tse-I, VIJGEN, Leen, DEHERTOGH, Pascale, FRANSEN, Els, CLEIREN, Erna, VAN DER HELM, Liesbet, NYANGUILE, Origène, TAHRI, Abdellah, AMSSOMS, Katie

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1a/1b Subtype Profiling of Nonnucleoside Polymerase Inhibitors of Hepatitis C Virus von NYANGUILE, Origène, DEVOGELAERE, Benoit, VANDERCRUYSSEN, Geneviève, VERMEIREN, Katrien, MOSTMANS, Wendy, DEHERTOGH, Pascale, DELOUVROY, Frédéric, VENDEVILLE, Sandrine, VANDYCK, Koen, DOCKX, Koen, CLEIREN, Ema, RABOISSON, Pierre, VIJGEN, Leen, SIMMEN, Kenneth A, FANNING, Gregory C, VAN DEN BROECK, Walter, PAUWELS, Frederik, CUMMINGS, Maxwell D, DE BONDT, Hendrik L, VOS, Ann M, BERKE, Jan M, LENZ, Oliver

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Discovery and Early Development of TMC647055, a Non-Nucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase von Cummings, Maxwell D., Lin, Tse-I, Hu, Lili, Tahri, Abdellah, McGowan, David, Amssoms, Katie, Last, Stefaan, Devogelaere, Benoit, Rouan, Marie-Claude, Vijgen, Leen, Berke, Jan Martin, Dehertogh, Pascale, Fransen, Els, Cleiren, Erna, van der Helm, Liesbet, Fanning, Gregory, Nyanguile, Origène, Simmen, Kenny, Van Remoortere, Pieter, Raboisson, Pierre, Vendeville, Sandrine

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Structure-Based Macrocyclization Yields Hepatitis C Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties von Cummings, Maxwell D., Lin, Tse-I, Hu, Lili, Tahri, Abdellah, McGowan, David, Amssoms, Katie, Last, Stefaan, Devogelaere, Benoit, Rouan, Marie-Claude, Vijgen, Leen, Berke, Jan Martin, Dehertogh, Pascale, Fransen, Els, Cleiren, Erna, van der Helm, Liesbet, Fanning, Gregory, Van Emelen, Kristof, Nyanguile, Origène, Simmen, Kenny, Raboisson, Pierre, Vendeville, Sandrine

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Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055 von Vendeville, Sandrine, Lin, Tse-I., Hu, Lili, Tahri, Abdellah, McGowan, David, Cummings, Maxwell D., Amssoms, Katie, Canard, Maxime, Last, Stefaan, Van den Steen, Iris, Devogelaere, Benoit, Rouan, Marie-Claude, Vijgen, Leen, Berke, Jan Martin, Dehertogh, Pascale, Fransen, Els, Cleiren, Erna, van der Helm, Liesbet, Fanning, Gregory, Van Emelen, Kristof, Nyanguile, Origène, Simmen, Kenny, Raboisson, Pierre

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Structure-Based Macrocyclization Yields HepatitisC Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties von Cummings, Maxwell D, Lin, Tse-I, Hu, Lili, Tahri, Abdellah, McGowan, David, Amssoms, Katie, Last, Stefaan, Devogelaere, Benoit, Rouan, Marie-Claude, Vijgen, Leen, Berke, Jan Martin, Dehertogh, Pascale, Fransen, Els, Cleiren, Erna, vanderHelm, Liesbet, Fanning, Gregory, VanEmelen, Kristof, Nyanguile, Origène, Simmen, Kenny, Raboisson, Pierre, Vendeville, Sandrine

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Structure-Based Macrocyclization Yields Hepatitis C Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties von Cummings, Maxwell D., Lin, Tse-I, Hu, Lili, Tahri, Abdellah, McGowan, David, Amssoms, Katie, Last, Stefaan, Devogelaere, Benoit, Rouan, Marie-Claude, Vijgen, Leen, Berke, Jan Martin, Dehertogh, Pascale, Fransen, Els, Cleiren, Erna, van der Helm, Liesbet, Fanning, Gregory, Van Emelen, Kristof, Nyanguile, Origène, Simmen, Kenny, Raboisson, Pierre, Vendeville, Sandrine

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Structure-Based Macrocyclization Yields HepatitisC Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties von Cummings, Maxwell D, Lin, Tse-I, Hu, Lili, Tahri, Abdellah, McGowan, David, Amssoms, Katie, Last, Stefaan, Devogelaere, Benoit, Rouan, Marie-Claude, Vijgen, Leen, Berke, Jan Martin, Dehertogh, Pascale, Fransen, Els, Cleiren, Erna, vanderHelm, Liesbet, Fanning, Gregory, VanEmelen, Kristof, Nyanguile, Origène, Simmen, Kenny, Raboisson, Pierre, Vendeville, Sandrine

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