A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa von Lu, Genmin, DeGuzman, Francis R, Hollenbach, Stanley J, Karbarz, Mark J, Abe, Keith, Lee, Gail, Luan, Peng, Hutchaleelaha, Athiwat, Inagaki, Mayuko, Conley, Pamela B, Phillips, David R, Sinha, Uma

Volltext

PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model von Reilly, Michael P., Sinha, Uma, André, Pierrette, Taylor, Scott M., Pak, Yvonne, DeGuzman, Francis R., Nanda, Nisha, Pandey, Anjali, Stolla, Moritz, Bergmeier, Wolfgang, McKenzie, Steven E.

Volltext

Integrin cytoplasmic tyrosine motif is required for outside-in αIIbβ3 signalling and platelet function von Phillips, David R, Law, Debbie A, DeGuzman, Francis R, Heiser, Patrick, Ministri-Madrid, Kathleen, Killeen, Nigel

Volltext

Recombinant Antidote for Reversal of Anticoagulation by Factor Xa Inhibitors von Lu, Genmin, DeGuzman, Francis R., Lakhotia, Sanjay, Hollenbach, Stanley J, Phillips, David R, Sinha, Uma

Volltext

Inhibition of Syk Activity Is Sufficient for Inhibitory Effect in Animal Models of Autoimmune Diseases von Hollenbach, Stanley J, Coffey, Greg, DeGuzman, Francis R, Inagaki, Mayuko, Pandey, Anjali, Jia, Zhaozhong J, Xu, Qing, Bauer, Shawn, Baker, Dale, Nanda, Nisha, Phillips, David R, Sinha, Uma

Volltext

PRT060318, a Novel Syk Inhibitor, Prevents Heparin-Induced Thrombocytopenia in a Transgenic Mouse Model von Reilly, Michael P., Sinha, Uma, Andre, Pierrette, Taylor, Scott M., Pak, Yvonne, DeGuzman, Francis R., Nanda, Nisha, Pandey, Anjali, McKenzie, Steven E.

Volltext

Integrin cytoplasmic tyrosine motif is required for outside-in [alpha]IIb[beta]3 signalling and platelet function von Law, Debbie A, DeGuzman, Francis R, Heiser, Patrick, Ministri-Madrid, Kathleen, Killeen, Nigel, Phillips, David R

Volltext

Integrin cytoplasmic tyrosine motif is required for outside-in alpha-llb-beta-3 signalling and platelet function von Law, Debbie A, DeGuzman, Francis R, Heiser, Patrick, Ministri-Madrid, Kathleen

Volltext

Andexanet alfa effectively reverses edoxaban anticoagulation effects and associated bleeding in a rabbit acute hemorrhage model von Lu, Genmin, Pine, Polly, Leeds, Janet M, DeGuzman, Francis, Pratikhya, Pratikhya, Lin, Joyce, Malinowski, John, Hollenbach, Stanley J, Curnutte, John T, Conley, Pamela B

Volltext

Shape of (101955) Bennu indicative of a rubble pile with internal stiffness von Barnouin, O. S., Daly, M. G., Palmer, E. E., Gaskell, R. W., Weirich, J. R., Johnson, C. L., Al Asad, M. M., Roberts, J. H., Perry, M. E., Susorney, H. C. M., Daly, R. T., Bierhaus, E. B., Seabrook, J. A., Espiritu, R. C., Nair, A. H., Nguyen, L., Neumann, G. A., Ernst, C. M., Boynton, W. V., Nolan, M. C., Adam, C. D., Moreau, M. C., Rizk, B., Drouet D’Aubigny, C. Y., Jawin, E. R., Walsh, K. J., Michel, P., Schwartz, S. R., Ballouz, R.-L., Mazarico, E. M., Scheeres, D. J., McMahon, J. W., Bottke, W. F., Sugita, S., Hirata, N., Hirata, N., Watanabe, S.-i., Burke, K. N., DellaGiustina, D. N., Bennett, C. A., Lauretta, D. S.

Volltext

Specific inhibition of spleen tyrosine kinase suppresses leukocyte immune function and inflammation in animal models of rheumatoid arthritis von Coffey, Greg, DeGuzman, Francis, Inagaki, Mayuko, Pak, Yvonne, Delaney, Suzanne M, Ives, Dan, Betz, Andreas, Jia, Zhaozhong J, Pandey, Anjali, Baker, Dale, Hollenbach, Stanley J, Phillips, David R, Sinha, Uma

Volltext

Predictive Biomarker Analysis from the GBT021601 Survival Study in Townes Sickle Mice von Pochron, Mira Patel, Sun, Jiaxin, Potdar, Alka A, Alt, Carsten, DeGuzman, Francis, Connor, Michael W., Cathers, Brian, Dufu, Kobina, Archer, David R

Volltext

P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries von Andre, Patrick, Delaney, Suzanne M, LaRocca, Thomas, Vincent, Diana, DeGuzman, Francis, Jurek, Marzena, Koller, Beverley, Phillips, David R, Conley, Pamela B

Volltext

Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling von Nanda, Nisha, Andre, Patrick, Bao, Ming, Clauser, Karl, Deguzman, Francis, Howie, Duncan, Conley, Pamela B., Terhorst, Cox, Phillips, David R.

Volltext

A Thrombin Receptor Function for Platelet Glycoprotein Ib-IX Unmasked by Cleavage of Glycoprotein V von Ramakrishnan, Vanitha, DeGuzman, Francis, Bao, Ming, Hall, Scott W., Leung, Lawrence L., Phillips, David R.

Volltext

Thienopyridines, but not elinogrel, result in off-target effects at the vessel wall that contribute to bleeding von André, Patrick, DeGuzman, Francis, Haberstock-Debic, Helena, Mills, Scott, Pak, Yvonne, Inagaki, Mayuko, Pandey, Anjali, Hollenbach, Stanley, Phillips, David R, Conley, Pamela B

Volltext

Increased Thrombin Responsiveness in Platelets from Mice Lacking Glycoprotein V von Ramakrishnan, Vanitha, Reeves, Peter S., DeGuzman, Francis, Deshpande, Usha, Ministri-Madrid, Kathleen, DuBridge, Robert B., Phillips, David R.

Volltext

SERT Ileu425Val in autism, Asperger syndrome and obsessive-compulsive disorder von Wendland, Jens R, DeGuzman, Theresa B, McMahon, Francis, Rudnick, Gary, Detera-Wadleigh, Sevilla D, Murphy, Dennis L

Volltext

Abstract 1718: Combination of Direct Acting FXa Inhibitor and P2Y 12 Antagonist at Non-Effective doses Provides Significant Inhibition of Arterial Thrombosis von Andre, Patrick, Conley, Pamela B, Deguzman, Francis, Pak, Yvonne, Inagaki, Mayuko, Sinha, Uma, Phillips, David R

Volltext

Specific Inhibition of Syk Suppresses Leukocyte Immune Function and Alleviates Inflammation In Rodent Models of Rheumatoid Arthritis von Coffey, Greg, Francis, DeGuzman, Inagaki, Mayuko, Pak, Yvonne, Delaney, Suzanne, Betz, Andreas, Jia, Zhaozhong J, Xu, Qing, Bauer, Shawn, Song, Yonghong, Pandey, Anjali, Baker, Dale, Hollenbach, Stanley, Phillips, David R., Sinha, Uma

Volltext