Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases von DeBalsi, Karen L, Hoff, Kirsten E, Copeland, William C

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Muscle-Specific Deletion of Carnitine Acetyltransferase Compromises Glucose Tolerance and Metabolic Flexibility von Muoio, Deborah M., Noland, Robert C., Kovalik, Jean-Paul, Seiler, Sarah E., Davies, Michael N., DeBalsi, Karen L., Ilkayeva, Olga R., Stevens, Robert D., Kheterpal, Indu, Zhang, Jingying, Covington, Jeffrey D., Bajpeyi, Sudip, Ravussin, Eric, Kraus, William, Koves, Timothy R., Mynatt, Randall L.

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Carnitine Acetyltransferase Mitigates Metabolic Inertia and Muscle Fatigue during Exercise von Seiler, Sarah E., Koves, Timothy R., Gooding, Jessica R., Wong, Kari E., Stevens, Robert D., Ilkayeva, Olga R., Wittmann, April H., DeBalsi, Karen L., Davies, Michael N., Lindeboom, Lucas, Schrauwen, Patrick, Schrauwen-Hinderling, Vera B., Muoio, Deborah M.

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Characterization of the human homozygous R182W POLG2 mutation in mitochondrial DNA depletion syndrome von Hoff, Kirsten E, DeBalsi, Karen L, Sanchez-Quintero, Maria J, Longley, Matthew J, Hirano, Michio, Naini, Ali B, Copeland, William C

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PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans von Koves, Timothy R., Sparks, Lauren M., Kovalik, J.P., Mosedale, Merrie, Arumugam, Ramamani, DeBalsi, Karen L., Everingham, Karen, Thorne, Leigh, Phielix, Esther, Meex, Ruth C., Kien, C. Lawrence, Hesselink, Matthijs K.C., Schrauwen, Patrick, Muoio, Deborah M.

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Integrating Genome Sequencing and Untargeted Metabolomics in Monozygotic Twins with a Rare Complex Neurological Disorder von Shaath, Rulan, Al-Maraghi, Aljazi, Ali, Haytham, AlRayahi, Jehan, Kennedy, Adam D, DeBalsi, Karen L, Hussein, Sura, Elbashir, Najwa, Padmajeya, Sujitha S, Palaniswamy, Sasirekha, Elsea, Sarah H, Akil, Ammira A, Yousri, Noha A, Fakhro, Khalid A

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A Case Study of Dysfunctional Nicotinamide Metabolism in a 20-Year-Old Male von DeBalsi, Karen L, Newman, John H, Sommerville, Laura J, Phillips, 3rd, John A, Hamid, Rizwan, Cogan, Joy, Fessel, Joshua P, Evans, Anne M, Undiagnosed Diseases Network, Kennedy, Adam D

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Obesity and lipid stress inhibit carnitine acetyltransferase activity[S] von Seiler, Sarah E., Martin, Ola J., Noland, Robert C., Slentz, Dorothy H., DeBalsi, Karen L., Ilkayeva, Olga R., An, Jie, Newgard, Christopher B., Koves, Timothy R., Muoio, Deborah M.

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Synergistic Effects of the in cis T251I and P587L Mitochondrial DNA Polymerase γ Disease Mutations von DeBalsi, Karen L., Longley, Matthew J., Hoff, Kirsten E., Copeland, William C.

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Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction von Wong, Kari E, Mikus, Catherine R, Slentz, Dorothy H, Seiler, Sarah E, DeBalsi, Karen L, Ilkayeva, Olga R, Crain, Karen I, Kinter, Michael T, Kien, C Lawrence, Stevens, Robert D, Muoio, Deborah M

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POLG2 disease variants: analyses reveal a dominant negative heterodimer, altered mitochondrial localization and impaired respiratory capacity von Young, Matthew J, Humble, Margaret M, DeBalsi, Karen L, Sun, Kathie Y, Copeland, William C

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Targeted Metabolomics Connects Thioredoxin-interacting Protein (TXNIP) to Mitochondrial Fuel Selection and Regulation of Specific Oxidoreductase Enzymes in Skeletal Muscle von DeBalsi, Karen L., Wong, Kari E., Koves, Timothy R., Slentz, Dorothy H., Seiler, Sarah E., Wittmann, April H., Ilkayeva, Olga R., Stevens, Robert D., Perry, Christopher G.R., Lark, Daniel S., Hui, Simon T., Szweda, Luke, Neufer, P. Darrell, Muoio, Deborah M.

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Biochemical characterization of PolG exonuclease disease mutations von DeBalsi, Karen L., Longley, Matthew J., Hoff, Kirsten E., Gattis, Samuel G., Copeland, William C.

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Muscle-Specific Overexpression of PGC-1a Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction von Wong, Kari E, Mikus, Catherine R, Slentz, Dorothy H, Seiler, Sarah E, DeBalsi, Karen L, Ilkayeva, Olga R, Crain, Karen I, Kinter, Michael T, Kien, C Lawrence, Stevens, Robert D, Muoio, Deborah M

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Integrating Genome Sequencing and Untargeted Metabolomics in Monozygotic Twins with a Rare Complex Neurological Disorder von Shaath, Rulan, Al-Maraghi, Aljazi, Ali, Haytham, AlRayahi, Jehan, Kennedy, Adam D, DeBalsi, Karen L, Hussein, Sura, Elbashir, Najwa, Padmajeya, Sujitha S, Palaniswamy, Sasirekha, Elsea, Sarah H, Akil, Ammira A, Yousri, Noha A, Fakhro, Khalid A

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