Functional Precision Oncology: The Next Frontier to Improve Glioblastoma Outcome? von Panovska, Dena, De Smet, Frederik

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Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization von Pombo Antunes, Ana Rita, Scheyltjens, Isabelle, Lodi, Francesca, Messiaen, Julie, Antoranz, Asier, Duerinck, Johnny, Kancheva, Daliya, Martens, Liesbet, De Vlaminck, Karen, Van Hove, Hannah, Kjølner Hansen, Signe Schmidt, Bosisio, Francesca Maria, Van der Borght, Koen, De Vleeschouwer, Steven, Sciot, Raf, Bouwens, Luc, Verfaillie, Michiel, Vandamme, Niels, Vandenbroucke, Roosmarijn E., De Wever, Olivier, Saeys, Yvan, Guilliams, Martin, Gysemans, Conny, Neyns, Bart, De Smet, Frederik, Lambrechts, Diether, Van Ginderachter, Jo A., Movahedi, Kiavash

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Allosteric targeting of receptor tyrosine kinases von De Smet, Frederik, Christopoulos, Arthur, Carmeliet, Peter

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An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates von Goveia, Jermaine, Rohlenova, Katerina, Taverna, Federico, Treps, Lucas, Conradi, Lena-Christin, Pircher, Andreas, Geldhof, Vincent, de Rooij, Laura P.M.H., Kalucka, Joanna, Sokol, Liliana, García-Caballero, Melissa, Zheng, Yingfeng, Qian, Junbin, Teuwen, Laure-Anne, Khan, Shawez, Boeckx, Bram, Wauters, Els, Decaluwé, Herbert, De Leyn, Paul, Vansteenkiste, Johan, Weynand, Birgit, Sagaert, Xavier, Verbeken, Erik, Wolthuis, Albert, Topal, Baki, Everaerts, Wouter, Bohnenberger, Hanibal, Emmert, Alexander, Panovska, Dena, De Smet, Frederik, Staal, Frank J.T., Mclaughlin, Rene J., Impens, Francis, Lagani, Vincenzo, Vinckier, Stefan, Mazzone, Massimiliano, Schoonjans, Luc, Dewerchin, Mieke, Eelen, Guy, Karakach, Tobias K., Yang, Huanming, Wang, Jian, Bolund, Lars, Lin, Lin, Thienpont, Bernard, Li, Xuri, Lambrechts, Diether, Luo, Yonglun, Carmeliet, Peter

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Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages von Wauters, Els, Van Mol, Pierre, Garg, Abhishek Dinkarnath, Jansen, Sander, Van Herck, Yannick, Vanderbeke, Lore, Bassez, Ayse, Boeckx, Bram, Malengier-Devlies, Bert, Timmerman, Anna, Van Brussel, Thomas, Van Buyten, Tina, Schepers, Rogier, Heylen, Elisabeth, Dauwe, Dieter, Dooms, Christophe, Gunst, Jan, Hermans, Greet, Meersseman, Philippe, Testelmans, Dries, Yserbyt, Jonas, Tejpar, Sabine, De Wever, Walter, Matthys, Patrick, Neyts, Johan, Wauters, Joost, Qian, Junbin, Lambrechts, Diether

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TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry von Baggen, Jim, Jacquemyn, Maarten, Persoons, Leentje, Vanstreels, Els, Pye, Valerie E., Wrobel, Antoni G., Calvaresi, Valeria, Martin, Stephen R., Roustan, Chloë, Cronin, Nora B., Reading, Eamonn, Thibaut, Hendrik Jan, Vercruysse, Thomas, Maes, Piet, De Smet, Frederik, Yee, Angie, Nivitchanyong, Toey, Roell, Marina, Franco-Hernandez, Natalia, Rhinn, Herve, Mamchak, Alusha Andre, Ah Young-Chapon, Maxime, Brown, Eric, Cherepanov, Peter, Daelemans, Dirk

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Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis von Rohlenova, Katerina, Goveia, Jermaine, García-Caballero, Melissa, Subramanian, Abhishek, Kalucka, Joanna, Treps, Lucas, Falkenberg, Kim D., de Rooij, Laura P.M.H., Zheng, Yingfeng, Lin, Lin, Sokol, Liliana, Teuwen, Laure-Anne, Geldhof, Vincent, Taverna, Federico, Pircher, Andreas, Conradi, Lena-Christin, Khan, Shawez, Stegen, Steve, Panovska, Dena, De Smet, Frederik, Staal, Frank J.T., Mclaughlin, Rene J., Vinckier, Stefan, Van Bergen, Tine, Ectors, Nadine, De Haes, Patrik, Wang, Jian, Bolund, Lars, Schoonjans, Luc, Karakach, Tobias K., Yang, Huanming, Carmeliet, Geert, Liu, Yizhi, Thienpont, Bernard, Dewerchin, Mieke, Eelen, Guy, Li, Xuri, Luo, Yonglun, Carmeliet, Peter

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The tumor micro-environment in pediatric glioma: friend or foe? von Messiaen, Julie, Jacobs, Sandra A., De Smet, Frederik

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Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way von Carmeliet, Peter, De Smet, Frederik, Loges, Sonja, Mazzone, Massimiliano

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Antioxidant network-based signatures cluster glioblastoma into distinct redox-resistant phenotypes von Yang, Yihan, More, Sanket, De Smet, Frederik, De Vleeschouwer, Steven, Agostinis, Patrizia

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A Deep Learning-Based Strategy to Initiate Diesel Particle Filter Regeneration von Aslandere, Turgay, Fan, Ke, DeSmet, Frederik, Roettger, Daniel

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Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection von Lamarthée, Baptiste, Callemeyn, Jasper, Van Herck, Yannick, Antoranz, Asier, Anglicheau, Dany, Boada, Patrick, Becker, Jan Ulrich, Debyser, Tim, De Smet, Frederik, De Vusser, Katrien, Eloudzeri, Maëva, Franken, Amelie, Gwinner, Wilfried, Koshy, Priyanka, Kuypers, Dirk, Lambrechts, Diether, Marquet, Pierre, Mathias, Virginie, Rabant, Marion, Sarwal, Minnie M., Senev, Aleksandar, Sigdel, Tara K., Sprangers, Ben, Thaunat, Olivier, Tinel, Claire, Van Brussel, Thomas, Van Craenenbroeck, Amaryllis, Van Loon, Elisabet, Vaulet, Thibaut, Bosisio, Francesca, Naesens, Maarten

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Gene prioritization through genomic data fusion von Aerts, Stein, Lambrechts, Diether, Maity, Sunit, Van Loo, Peter, Coessens, Bert, De Smet, Frederik, Tranchevent, Leon-Charles, De Moor, Bart, Marynen, Peter, Hassan, Bassem, Carmeliet, Peter, Moreau, Yves

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An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates von Goveia, Jermaine, Rohlenova, Katerina, Taverna, Federico, Treps, Lucas, Conradi, Lena-Christin, Pircher, Andreas, Geldhof, Vincent, de Rooij, Laura P.M.H., Kalucka, Joanna, Sokol, Liliana, García-Caballero, Melissa, Zheng, Yingfeng, Qian, Junbin, Teuwen, Laure-Anne, Khan, Shawez, Boeckx, Bram, Wauters, Els, Decaluwé, Herbert, De Leyn, Paul, Vansteenkiste, Johan, Weynand, Birgit, Sagaert, Xavier, Verbeken, Erik, Wolthuis, Albert, Topal, Baki, Everaerts, Wouter, Bohnenberger, Hanibal, Emmert, Alexander, Panovska, Dena, De Smet, Frederik, Staal, Frank J.T., Mclaughlin, Rene J., Impens, Francis, Lagani, Vincenzo, Vinckier, Stefan, Mazzone, Massimiliano, Schoonjans, Luc, Dewerchin, Mieke, Eelen, Guy, Karakach, Tobias K., Yang, Huanming, Wang, Jian, Bolund, Lars, Lin, Lin, Thienpont, Bernard, Li, Xuri, Lambrechts, Diether, Luo, Yonglun, Carmeliet, Peter

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Next-Generation Pathology Using Multiplexed Immunohistochemistry: Mapping Tissue Architecture at Single-Cell Level von Bosisio, Francesca Maria, Van Herck, Yannick, Messiaen, Julie, Bolognesi, Maddalena Maria, Marcelis, Lukas, Van Haele, Matthias, Cattoretti, Giorgio, Antoranz, Asier, De Smet, Frederik

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Multiplexed Immunohistochemistry and Digital Pathology as the Foundation for Next-Generation Pathology in Melanoma: Methodological Comparison and Future Clinical Applications von Van Herck, Yannick, Antoranz, Asier, Andhari, Madhavi Dipak, Milli, Giorgia, Bechter, Oliver, De Smet, Frederik, Bosisio, Francesca Maria

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IL-1R signaling drives enteric glia-macrophage interactions in colorectal cancer von van Baarle, Lies, De Simone, Veronica, Schneider, Linda, Santhosh, Sneha, Abdurahiman, Saeed, Biscu, Francesca, Schneider, Reiner, Zanoletti, Lisa, Siqueira de Mello, Renata, Verbandt, Sara, Hu, Zedong, Stakenborg, Michelle, Ke, Bo-Jun, Stakenborg, Nathalie, Salvador Laureano, Raquel, García-Reyes, Balbina, Henn, Jonas, Toma, Marieta, Vanmechelen, Maxime, Boeckxstaens, Guy, De Smet, Frederik, Garg, Abhishek D., Ibiza, Sales, Tejpar, Sabine, Wehner, Sven, Matteoli, Gianluca

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Molecular Mechanism of SSR128129E, an Extracellularly Acting, Small-Molecule, Allosteric Inhibitor of FGF Receptor Signaling von Herbert, Corentin, Schieborr, Ulrich, Saxena, Krishna, Juraszek, Jarek, De Smet, Frederik, Alcouffe, Chantal, Bianciotto, Marc, Saladino, Giorgio, Sibrac, David, Kudlinzki, Denis, Sreeramulu, Sridhar, Brown, Alan, Rigon, Patrice, Herault, Jean-Pascal, Lassalle, Gilbert, Blundell, Tom L., Rousseau, Frederic, Gils, Ann, Schymkowitz, Joost, Tompa, Peter, Herbert, Jean-Marc, Carmeliet, Peter, Gervasio, Francesco Luigi, Schwalbe, Harald, Bono, Françoise

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Inhibition of Tumor Angiogenesis and Growth by a Small-Molecule Multi-FGF Receptor Blocker with Allosteric Properties von Bono, Françoise, De Smet, Frederik, Herbert, Corentin, De Bock, Katrien, Georgiadou, Maria, Fons, Pierre, Tjwa, Marc, Alcouffe, Chantal, Ny, Annelii, Bianciotto, Marc, Jonckx, Bart, Murakami, Masahiro, Lanahan, Anthony A., Michielsen, Christof, Sibrac, David, Dol-Gleizes, Frédérique, Mazzone, Massimiliano, Zacchigna, Serena, Herault, Jean-Pascal, Fischer, Christian, Rigon, Patrice, Ruiz de Almodovar, Carmen, Claes, Filip, Blanc, Isabelle, Poesen, Koen, Zhang, Jie, Segura, Inmaculada, Gueguen, Geneviève, Bordes, Marie-Françoise, Lambrechts, Diether, Broussy, Roselyne, van de Wouwer, Marlies, Michaux, Corinne, Shimada, Toru, Jean, Isabelle, Blacher, Silvia, Noel, Agnès, Motte, Patrick, Rom, Eran, Rakic, Jean-Marie, Katsuma, Susumu, Schaeffer, Paul, Yayon, Avner, Van Schepdael, Ann, Schwalbe, Harald, Gervasio, Francesco Luigi, Carmeliet, Geert, Rozensky, Jef, Dewerchin, Mieke, Simons, Michael, Christopoulos, Arthur, Herbert, Jean-Marc, Carmeliet, Peter

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Structural hot spots for the solubility of globular proteins von Ganesan, Ashok, Siekierska, Aleksandra, Beerten, Jacinte, Brams, Marijke, Van Durme, Joost, De Baets, Greet, Van der Kant, Rob, Gallardo, Rodrigo, Ramakers, Meine, Langenberg, Tobias, Wilkinson, Hannah, De Smet, Frederik, Ulens, Chris, Rousseau, Frederic, Schymkowitz, Joost

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