Delivery routes matter: Safety and efficacy of intratumoral immunotherapy von De Lombaerde, Emily, De Wever, Olivier, De Geest, Bruno G.

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Combinatorial Screening of Biscarbamate Ionizable Lipids Identifies a Low Reactogenicity Lipid for Lipid Nanoparticle mRNA Delivery von De Lombaerde, Emily, Chen, Yong, Ye, Tingting, Deckers, Julie, Mencarelli, Giulia, De Swarte, Kim, Lauwers, Heleen, De Coen, Ruben, Kasmi, Sabah, Bevers, Sanne, Kuchmiy, Anna, Bogaert, Bram, Baekens, Lies, Zhong, Zifu, Lamoot, Alexander, Sanders, Niek N., Lambrecht, Bart N., Baptista, Antonio P., De Koker, Stefaan, De Geest, Bruno G.

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CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity von Ye, Tingting, Zhong, Zifu, Cappellesso, Federica, Deswarte, Kim, Chen, Yong, Lauwers, Heleen, De Lombaerde, Emily, Gontsarik, Mark, Lienenklaus, Stefan, Van Lysebetten, Dorien, Sanders, Niek N., Lambrecht, Bart N., De Koker, Stefaan, Laoui, Damya, De Geest, Bruno G.

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Amplification of Protein Expression by Self-Amplifying mRNA Delivered in Lipid Nanoparticles Containing a β‑Aminoester Ionizable Lipid Correlates with Reduced Innate Immune Activat... von De Lombaerde, Emily, Cui, Xiaole, Chen, Yong, Zhong, Zifu, Deckers, Julie, Mencarelli, Giulia, Opsomer, Lisa, Wang, Haixiu, De Baere, Jamie, Lienenklaus, Stefan, Lambrecht, Bart N., Sanders, Niek N., De Geest, Bruno G.

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Combinatorial screening of biscarbamate ionizable lipids identifies a low reactogenicity lipid for lipid nanoparticle mRNA delivery von De Lombaerde, Emily, Chen, Yong, Ye, Tingting, Deckers, Julie, Mencarelli, Giulia, Deswarte, Kim, Lauwers, Heleen, De Coen, Ruben, Kasmi, Sabah, Bevers, Sanne, Kuchmiy, Anna, Bogaert, Bram, Baekens, Lies, Zhong, Zifu, Lamoot, Alexander, Sanders, Niek, Lambrecht, Bart, Pires da Silva Baptista, Antonio, De Koker, Stefaan, De Geest, Bruno

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Lipid Nanoparticle Encapsulation Empowers Poly(I:C) to Activate Cytoplasmic RLRs and Thereby Increases Its Adjuvanticity von Lamoot, Alexander, Jangra, Sonia, Laghlali, Gabriel, Warang, Prajakta, Singh, Gagandeep, Chang, Lauren A., Park, Seok‐Chan, Singh, Gagandeep, De Swarte, Kim, Zhong, Zifu, Louage, Benoit, De Lombaerde, Emily, Ye, Tingting, Chen, Yong, Cuadrado‐Castano, Sara, Lienenklaus, Stefan, Sanders, Niek N., Lambrecht, Bart N., García‐Sastre, Adolfo, Schotsaert, Michael, De Geest, Bruno G.

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Lipid nanoparticle encapsulation empowers poly(I:C) to activate cytoplasmic RLRs and thereby increases its adjuvanticity von Lamoot, Alexander, Jangra, Sonia, Laghlali, Gabriel, Warang, Prajakta, Singh, Gagandeep, Chang, Lauren A, Park, Seok‐Chan, Deswarte, Kim, Zhong, Zifu, Louage, Benoit, De Lombaerde, Emily, Ye, Tingting, Chen, Yong, Cuadrado‐Castano, Sara, Lienenklaus, Stefan, Sanders, Niek, Lambrecht, Bart, García‐Sastre, Adolfo, Schotsaert, Michael, De Geest, Bruno

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Successful batch and continuous lyophilization of mRNA LNP formulations depend on cryoprotectants and ionizable lipids von Lamoot, Alexander, Lammens, Joris, De Lombaerde, Emily, Zhong, Zifu, Gontsarik, Mark, Chen, Yong, De Beer, Thomas, De Geest, Bruno

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Successful batch and continuous lyophilization of mRNA LNP formulations depend on cryoprotectants and ionizable lipids von Lamoot, Alexander, Lammens, Joris, De Lombaerde, Emily, Zhong, Zifu, Gontsarik, Mark, Chen, Yong, De Beer, Thomas R. M, De Geest, Bruno G

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Lipid Nanoparticle Delivery Alters the Adjuvanticity of the TLR9 Agonist CpG by Innate Immune Activation in Lymphoid Tissue von Zhong, Zifu, Chen, Yong, Deswarte, Kim, Lauwers, Heleen, De Lombaerde, Emily, Cui, Xiaole, Van Herck, Simon, Ye, Tingting, Gontsarik, Mark, Lienenklaus, Stefan, Sanders, Niek N., Lambrecht, Bart N., De Koker, Stefaan, De Geest, Bruno G.

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Lipid nanoparticle delivery alters the adjuvanticity of the TLR9 agonist CpG by innate immune activation in lymphoid tissue von Zhong, Zifu, Chen, Yong, Deswarte, Kim, Lauwers, Heleen, De Lombaerde, Emily, Cui, Xiaole, Van Herck, Simon, Ye, Tingting, Gontsarik, Mark, Lienenklaus, Stefan, Sanders, Niek, Lambrecht, Bart, De Koker, Stefaan, De Geest, Bruno

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IONIZABLE LIPIDS AND LIPID NANOPARTICLES COMPRISING SAID IONIZABLE LIPIDS FOR DELIVERY OF THERAPEUTIC AGENTS von ZHONG, Zifu, DE GEEST, Bruno, CHEN, Yong, SANDERS, Niek, DE LOMBAERDE, Emily

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IONIZABLE LIPIDS AND LIPID NANOPARTICLES COMPRISING SAID IONIZABLE LIPIDS FOR DELIVERY OF THERAPEUTIC AGENTS von ZHONG, Zifu, DE GEEST, Bruno, CHEN, Yong, SANDERS, Niek, DE LOMBAERDE, Emily

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