Drug Repurposing in Rare Diseases: An Integrative Study of Drug Screening and Transcriptomic Analysis in Nephropathic Cystinosis von Bellomo, Francesco, De Leo, Ester, Taranta, Anna, Giaquinto, Laura, Di Giovamberardino, Gianna, Montefusco, Sandro, Rega, Laura Rita, Pastore, Anna, Medina, Diego Luis, Di Bernardo, Diego, De Matteis, Maria Antonietta, Emma, Francesco

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Long-term effects of luteolin in a mouse model of nephropathic cystinosis von De Leo, Ester, Taranta, Anna, Raso, Roberto, Pezzullo, Marco, Piccione, Michela, Matteo, Valentina, Vitale, Alessia, Bellomo, Francesco, Goffredo, Bianca Maria, Diomedi Camassei, Francesca, Prencipe, Giusi, Rega, Laura Rita, Emma, Francesco

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Nlrp2 deletion ameliorates kidney damage in a mouse model of cystinosis von Rossi, Marianna Nicoletta, Matteo, Valentina, Diomedi-Camassei, Francesca, De Leo, Ester, Devuyst, Olivier, Lamkanfi, Mohamed, Caiello, Ivan, Loricchio, Elena, Bellomo, Francesco, Taranta, Anna, Emma, Francesco, De Benedetti, Fabrizio, Prencipe, Giusi

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Mitochondrial Dynamics of Proximal Tubular Epithelial Cells in Nephropathic Cystinosis von De Rasmo, Domenico, Signorile, Anna, De Leo, Ester, Polishchuk, Elena V., Ferretta, Anna, Raso, Roberto, Russo, Silvia, Polishchuk, Roman, Emma, Francesco, Bellomo, Francesco

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Defective Cystinosin, Aberrant Autophagy-Endolysosome Pathways, and Storage Disease: Towards Assembling the Puzzle von Rega, Laura Rita, De Leo, Ester, Nieri, Daniela, Luciani, Alessandro

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Biochemical Characterization of a Thermostable Adenosylmethionine Synthetase from the Archaeon Pyrococcus Furiosus with High Catalytic Power von Porcelli, Marina, Ilisso, Concetta Paola, De Leo, Ester, Cacciapuoti, Giovanna

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New Determinants in the Catalytic Mechanism of Nucleoside Hydrolases from the Structures of Two Isozymes from Sulfolobus solfataricus von Minici, Claudia, Cacciapuoti, Giovanna, De Leo, Ester, Porcelli, Marina, Degano, Massimo

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Benefits and Toxicity of Disulfiram in Preclinical Models of Nephropathic Cystinosis von Taranta, Anna, Elmonem, Mohamed A., Bellomo, Francesco, De Leo, Ester, Boenzi, Sara, Janssen, Manoe J., Jamalpoor, Amer, Cairoli, Sara, Pastore, Anna, De Stefanis, Cristiano, Colucci, Manuela, Rega, Laura R., Giovannoni, Isabella, Francalanci, Paola, van den Heuvel, Lambertus P., Dionisi-Vici, Carlo, Goffredo, Bianca M., Masereeuw, Rosalinde, Levtchenko, Elena, Emma, Francesco

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Genistein improves renal disease in a mouse model of nephropathic cystinosis: a comparison study with cysteamine von De Leo, Ester, Taranta, Anna, Raso, Roberto, Polishchuk, Elena, D’Oria, Valentina, Pezzullo, Marco, Goffredo, Bianca Maria, Cairoli, Sara, Bellomo, Francesco, Battafarano, Giulia, Camassei, Francesca Diomedi, Del Fattore, Andrea, Polishchuk, Roman, Emma, Francesco, Rega, Laura Rita

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Cell-Based Phenotypic Drug Screening Identifies Luteolin as Candidate Therapeutic for Nephropathic Cystinosis von De Leo, Ester, Elmonem, Mohamed A., Berlingerio, Sante Princiero, Berquez, Marine, Festa, Beatrice Paola, Raso, Roberto, Bellomo, Francesco, Starborg, Tobias, Janssen, Manoe Jacoba, Abbaszadeh, Zeinab, Cairoli, Sara, Goffredo, Bianca Maria, Masereeuw, Rosalinde, Devuyst, Olivier, Lowe, Martin, Levtchenko, Elena, Luciani, Alessandro, Emma, Francesco, Rega, Laura Rita

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Nlrp2 deletion ameliorates kidney damage in a mouse model of cystinosis von Rossi, Marianna Nicoletta, Matteo, Valentina, Diomedi-Camassei, Francesca, De Leo, Ester, Devuyst, Olivier, Lamkanfi, Mohamed, Caiello, Ivan, Loricchio, Elena, Bellomo, Francesco, Taranta, Anna, Emma, Francesco, De Benedetti, Fabrizio, Prencipe, Giusi

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Cystinosin-LKG rescues cystine accumulation and decreases apoptosis rate in cystinotic proximal tubular epithelial cells von Taranta, Anna, Bellomo, Francesco, Petrini, Stefania, Polishchuk, Elena, De Leo, Ester, Rega, Laura Rita, Pastore, Anna, Polishchuk, Roman, De Matteis, Maria Antonietta, Emma, Francesco

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Cell-Based Phenotypic Drug Screening Identifies Luteolin as Candidate Therapeutic for Nephropathic Cystinosis von De Leo, Ester, Elmonem, Mohamed A, Berlingerio, Sante Princiero, Berquez, Marine, Festa, Beatrice Paola, Raso, Roberto, Bellomo, Francesco, Starborg, Tobias, Janssen, Manoe Jacoba, Abbaszadeh, Zeinab, Cairoli, Sara, Goffredo, Bianca Maria, Masereeuw, Rosalinde, Devuyst, Olivier, Lowe, Martin, Levtchenko, Elena, Luciani, Alessandro, Emma, Francesco, Rega, Laura Rita

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Cell-Based Phenotypic Drug Screening Identifies Luteolin as Candidate Therapeutic for Nephropathic Cystinosis von De Leo, Ester, Elmonem, Mohamed A, Berlingerio, Sante Princiero, Berquez, Marine, Festa, Beatrice Paola, Raso, Roberto, Bellomo, Francesco, Starborg, Tobias, Janssen, Manoe Jacoba, Abbaszadeh, Zeinab, Cairoli, Sara, Goffredo, Bianca Maria, Masereeuw, Rosalinde, Devuyst, Olivier, Lowe, Martin, Levtchenko, Elena, Luciani, Alessandro, Emma, Francesco, Rega, Laura Rita

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Cell-Based Phenotypic Drug Screening Identifies Luteolin as Candidate Therapeutic for Nephropathic Cystinosis von De Leo, Ester, Elmonem, Mohamed A, Berlingerio, Sante Princiero, Berquez, Marine, Festa, Beatrice Paola, Raso, Roberto, Bellomo, Francesco, Starborg, Tobias, Janssen, Manoe Jacoba, Abbaszadeh, Zeinab, Cairoli, Sara, Goffredo, Bianca Maria, Masereeuw, Rosalinde, Devuyst, Olivier, Lowe, Martin, Levtchenko, Elena, Luciani, Alessandro, Emma, Francesco, Rega, Laura Rita

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Cell-Based Phenotypic Drug Screening Identifies Luteolin as Candidate Therapeutic for Nephropathic Cystinosis von De Leo, Ester, Elmonem, Mohamed A, Berlingerio, Sante Princiero, Berquez, Marine, Festa, Beatrice Paola, Raso, Roberto, Bellomo, Francesco, Starborg, Tobias, Janssen, Manoe Jacoba, Abbaszadeh, Zeinab, Cairoli, Sara, Goffredo, Bianca Maria, Masereeuw, Rosalinde, Devuyst, Olivier, Lowe, Martin, Levtchenko, Elena, Luciani, Alessandro, Emma, Francesco, Rega, Laura Rita

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Benefits and Toxicity of Disulfiram in Preclinical Models of Nephropathic Cystinosis von Taranta, Anna, elmonem, mohamed a, Bellomo, Francesco, Leo, Ester De, Boenzi, Sara, Janssen, Manoe J, Jamalpoor, Amer, Cairoli, Sara, Pastore, Anna, Stefanis, Cristiano De, Colucci, Manuela, Rega, Laura R, giovannoni, isabella, Francalanci, Paola, Heuvel, Lambertus P. van den, Dionisi-Vici, Carlo, Goffredo, Bianca M, Masereeuw, Rosalinde, Levtchenko, Elena, Emma, Francesco

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Benefits and Toxicity of Disulfiram in Preclinical Models of Nephropathic Cystinosis von Taranta, Anna, Elmonem, Mohamed A, Bellomo, Francesco, De Leo, Ester, Boenzi, Sara, Janssen, Manoe J, Jamalpoor, Amer, Cairoli, Sara, Pastore, Anna, De Stefanis, Cristiano, Colucci, Manuela, Rega, Laura R, Giovannoni, Isabella, Francalanci, Paola, van den Heuvel, Lambertus P, Dionisi-Vici, Carlo, Goffredo, Bianca M, Masereeuw, Rosalinde, Levtchenko, Elena, Emma, Francesco

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Site-directed mutagenesis gives insights into substrate specificity of Sulfolobus solfataricus purine-specific nucleoside hydrolase von Porcelli, Marina, De Leo, Ester, Marabotti, Anna, Cacciapuoti, Giovanna

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A Single 17D Yellow Fever Vaccination Provides Lifelong Immunity; Characterization of Yellow-Fever-Specific Neutralizing Antibody and T-Cell Responses after Vaccination von Wieten, Rosanne W, Jonker, Emile F F, van Leeuwen, Ester M M, Remmerswaal, Ester B M, Ten Berge, Ineke J M, de Visser, Adriëtte W, van Genderen, Perry J J, Goorhuis, Abraham, Visser, Leo G, Grobusch, Martin P, de Bree, Godelieve J

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