Huge variation in obtaining ethical permission for a non-interventional observational study in Europe von de Lange, Dylan W, Guidet, Bertrand, Andersen, Finn H, Artigas, Antonio, Bertolini, Guidio, Moreno, Rui, Christensen, Steffen, Cecconi, Maurizio, Agvald-Ohman, Christina, Gradisek, Primoz, Jung, Christian, Marsh, Brian J, Oeyen, Sandra, Bollen Pinto, Bernardo, Szczeklik, Wojciech, Watson, Ximena, Zafeiridis, Tilemachos, Flaatten, Hans

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The status of intensive care medicine research and a future agenda for very old patients in the ICU von Flaatten, H., de Lange, D. W., Artigas, A., Bin, D., Moreno, R., Christensen, S., Joynt, G. M., Bagshaw, Sean M., Sprung, C. L., Benoit, D., Soares, M., Guidet, B.

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The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years) von Flaatten, Hans, De Lange, Dylan W., Morandi, Alessandro, Andersen, Finn H., Artigas, Antonio, Bertolini, Guido, Boumendil, Ariane, Cecconi, Maurizio, Christensen, Steffen, Faraldi, Loredana, Fjølner, Jesper, Jung, Christian, Marsh, Brian, Moreno, Rui, Oeyen, Sandra, Öhman, Christina Agwald, Pinto, Bernardo Bollen, Soliman, Ivo W., Szczeklik, Wojciech, Valentin, Andreas, Watson, Ximena, Zaferidis, Tilemachos, Guidet, Bertrand

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Attitudes of physicians towards the care of critically ill elderly patients – a European survey von Guidet, B., De Lange, D. W., Christensen, S., Moreno, R., Fjølner, J., Dumas, G., Flaatten, H.

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Alarming increase in poisonings from recreational nitrous oxide use after a change in EU-legislation, inquiries to the Dutch Poisons Information Center von van Riel, A.J.H.P., Hunault, C.C., van den Hengel-Koot, I.S., Nugteren-van Lonkhuyzen, J.J., de Lange, D.W., Hondebrink, L.

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Validation of the clinical frailty score (CFS) in French language von Abraham, Paul, Courvoisier, Delphine S, Annweiler, Cedric, Lenoir, Cliff, Millien, Thomas, Dalmaz, Francoise, Flaatten, Hans, Moreno, Rui, Christensen, Steffen, de Lange, Dylan W, Guidet, Bertrand, Bendjelid, Karim, Walder, Bernhard, Bollen Pinto, Bernardo

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Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU... von Bassetti, Matteo, Scudeller, Luigia, Giacobbe, Daniele R., Lamoth, Frederic, Righi, Elda, Zuccaro, Valentina, Grecchi, Cecilia, Rebuffi, Chiara, Akova, Murat, Alastruey‐Izquierdo, Ana, Arikan‐Akdagli, Sevtap, Azoulay, Elie, Blot, Stijn I., Cornely, Oliver A., Lass‐Flörl, Cornelia, Koehler, Philipp, Cuenca‐Estrella, Manuel, de Lange, Dylan W., De Rosa, Francesco G., De Waele, Jan J., Dimopoulos, George, Garnacho‐Montero, José, Hoenigl, Martin, Kanj, Souha S., Maertens, Johan, Martin‐Loeches, Ignacio, Muñoz, Patricia, Kullberg, Bart J., Agvald‐Ohman, Christina, Poulakou, Garyphallia, Rello, Jordi, Sanguinetti, Maurizio, Taccone, Fabio S., Timsit, Jean‐François, Torres, Antoni, Vazquez, Jose A., Calandra, Thierry

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Sex-specific outcome disparities in very old patients admitted to intensive care medicine: a propensity matched analysis von Wernly, Bernhard, Bruno, Raphael Romano, Kelm, Malte, Boumendil, Ariane, Morandi, Alessandro, Andersen, Finn H., Artigas, Antonio, Finazzi, Stefano, Cecconi, Maurizio, Christensen, Steffen, Faraldi, Loredana, Lichtenauer, Michael, Muessig, Johanna M., Marsh, Brian, Moreno, Rui, Oeyen, Sandra, Öhman, Christina Agvald, Pinto, Bernado Bollen, Soliman, Ivo W., Szczeklik, Wojciech, Niederseer, David, Valentin, Andreas, Watson, Ximena, Leaver, Susannah, Boulanger, Carole, Walther, Sten, Schefold, Joerg C., Joannidis, Michael, Nalapko, Yuriy, Elhadi, Muhammed, Fjølner, Jesper, Zafeiridis, Tilemachos, De Lange, Dylan W., Guidet, Bertrand, Flaatten, Hans, Jung, Christian

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Differences in mortality in critically ill elderly patients during the second COVID-19 surge in Europe von Jung, C, Fjølner, J, Bruno, RR, Wernly, B, Artigas, A, Bollen Pinto, B, Schefold, JC, Wolff, G, Kelm, M, Beil, M, Sviri, S, van Heerden, PV, Szczeklik, W, Czuczwar, M, Joannidis, M, Oeyen, Sandra, Zafeiridis, T, Andersen, FH, Moreno, R, Leaver, S, Boumendil, A, De Lange, DW, Guidet, B, Flaatten, H, Study Group, COVIP

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Relationship between the Clinical Frailty Scale and short-term mortality in patients >= 80 years old acutely admitted to the ICU: a prospective cohort study von Fronczek, J, Polok, K, De Lange, DW, Jung, C, Beil, M, Rhodes, A, Fjolner, J, Gorka, J, Andersen, FH, Artigas, A, Cecconi, M, Christensen, S, Joannidis, M, Leaver, S, Marsh, B, Morandi, A, Moreno, R, Oeyen, S, Agvald-Ohman, C, Pinto, BB, Schefold, JC, Valentin, A, Walther, S, Watson, X, Zafeiridis, T, Sviri, S, Van Heerden, PV, Flaatten, H, Guidet, B, Szczeklik, W

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Therapy limitation in octogenarians in German intensive care units is associated with a longer length of stay and increased 30 days mortality: A prospective multicenter study von Bruno, Raphael Romano, Wernly, Bernhard, Beil, Michael, Muessig, Johanna M., Rahmel, Tim, Graf, Tobias, Meybohm, Patrick, Schaller, Stefan J., Allgäuer, Sebastian, Franz, Marcus, Westphal, Julian Georg, Barth, Eberhard, Ebelt, Henning, Fuest, Kristina, Horacek, Michael, Schuster, Michael, Dubler, Simon, Schering, Stefan, Wolff, Georg, Steiner, Stephan, Rabe, Christian, Dieck, Thorben, Lauten, Alexander, Sacher, Anne Lena, Brenner, Thorsten, Bloos, Frank, Jánosi, Rolf A., Simon, Philipp, Utzolino, Stefan, Kelm, Malte, De Lange, Dylan W., Guidet, Bertrand, Flaatten, Hans, Jung, Christian

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High PEEP/low FiO 2 ventilation is associated with lower mortality in COVID-19 von Goossen, Robin L, van Vliet, Relin, Bos, Lieuwe D J, Buiteman-Kruizinga, Laura A, Hollman, Markus W, Myatra, Sheila N, Neto, Ary Serpa, Spronk, Peter E, van der Woude, Meta C E, van Meenen, David M P, Paulus, Frederique, Schultz, Marcus J

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Sex-specific treatment characteristics and 30-day mortality outcomes of critically ill COVID-19 patients over 70 years of age-results from the prospective COVIP study von Wolff, G, Wernly, B, Flaatten, H, Fjølner, J, Bruno, RR, Artigas, A, Pinto, BB, Schefold, JC, Kelm, M, Binneboessel, S, Baldia, P, Beil, M, Sivri, S, van Heerden, PV, Szczeklik, W, Elhadi, M, Joannidis, M, Oeyen, Sandra, Flamm, M, Zafeiridis, T, Marsh, B, Andersen, FH, Moreno, R, Boumendil, A, De Lange, DW, Guidet, B, Leaver, S, Jung, C, COVIP Study, Group

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Cost-effectiveness of procalcitonin testing to guide antibiotic treatment duration in critically ill patients: results from a randomised controlled multicentre trial in the Netherl... von Kip, Michelle M A, van Oers, J.A, Shajiei, A, Beishuizen, Albertus, Girbes, A.R.J, de Jong, E, de Lange, DW, Nijsten, Maarten W N, IJzerman, M.J, Koffijberg, H, Kusters, R

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Increased mortality in systemic inflammatory response syndrome patients with high levels of coagulation factor VIIa von Hyseni, A., Kemperman, H., Lange, D. W., Groot, P. G., Linssen, M., Kesecioglu, J., Lisman, T., Roest, M.

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Sex-specific outcome disparities in very old patients admitted to intensive care medicine : a propensity matched analysis von Wernly, B, Bruno, RR, Kelm, M, Boumendil, A, Morandi, A, Andersen, FH, Artigas, A, Finazzi, S, Cecconi, M, Christensen, S, Faraldi, L, Lichtenauer, M, Muessig, JM, Marsh, B, Moreno, R, Oeyen, Sandra, Öhman, CA, Pinto, BB, Soliman, IW, Szczeklik, W, Niederseer, D, Valentin, A, Watson, X, Leaver, S, Boulanger, C, Walther, S, Schefold, JC, Joannidis, M, Nalapko, Y, Elhadi, M, Fjølner, J, Zafeiridis, T, De Lange, DW, Guidet, B, Flaatten, H, Jung, C, Study Group, VIP2

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Prognostication using SpO 2 /FiO 2 in invasively ventilated ICU patients with ARDS due to COVID-19 - Insights from the PRoVENT-COVID study von Roozeman, Jan-Paul, Mazzinari, Guido, Serpa Neto, Ary, Hollmann, Markus W, Paulus, Frederique, Schultz, Marcus J, Pisani, Luigi

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Lactate is associated with mortality in very old intensive care patients suffering from COVID-19 : results from an international observational study of 2860 patients von Bruno, RR, Wernly, B, Flaatten, H, Fjølner, J, Artigas, A, Bollen Pinto, B, Schefold, JC, Binnebössel, S, Baldia, PH, Kelm, M, Beil, M, Sigal, S, van Heerden, PV, Szczeklik, W, Elhadi, M, Joannidis, M, Oeyen, Sandra, Zafeiridis, T, Wollborn, J, Arche Banzo, MJ, Fuest, K, Marsh, B, Andersen, FH, Moreno, R, Leaver, S, Boumendil, A, De Lange, DW, Guidet, B, Jung, C, Study Group, COVIP

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Management of intoxicated patients – a descriptive outcome analysis of 4,267 ICU patients von Rezar, R, Jung, C, Mamandipoor, B, Seelmaier, C, Felder, TK, Lichtenauer, M, Wernly, S, Zwaag, SM, De Lange, DW, Wernly, B, Osmani, V

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Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units : protocol of the FUNgal infections Definitions in ICU patients (FUNDIC... von Bassetti, M, Scudeller, L, Giacobbe, DR, Lamoth, F, Righi, E, Zuccaro, V, Grecchi, C, Rebuffi, C, Akova, M, Alastruey-Izquierdo, A, Arıkan Akdagli, S, Azoulay, E, Blot, Stijn, Cornely, O, Lass-Flörl, C, Koehler, P, Cuenca-Estrella, M, de Lange, DW, De Rosa, FG, De Waele, Jan, Dimopoulos, G, Garnacho-Montero, J, Hoenigl, M, Kanj, SS, Maertens, J, Martin-Loeches, I, Muñoz, P, Kullberg, BJ, Agvald-Ohman, C, Poulakou, G, Rello, J, Sanguinetti, M, Taccone, FS, Timsit, JF, Torres, A, Vazquez, JA, Calandra, T

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