Scaffolds obtained from decellularized human extrahepatic bile ducts support organoids to establish functional biliary tissue in a dish von Willemse, Jorke, Roos, Floris J. M., Voogt, Iris J., Schurink, Ivo J., Bijvelds, Marcel, Jonge, Hugo R., Laan, Luc J. W., Jonge, Jeroen, Verstegen, Monique M. A.

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Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease von Kelly, Jennifer, Al-Rammahi, Miran, Daly, Kristian, Flanagan, Paul K., Urs, Arun, Cohen, Marta C., di Stefano, Gabriella, Bijvelds, Marcel J. C., Sheppard, David N., de Jonge, Hugo R., Seidler, Ursula E., Shirazi-Beechey, Soraya P.

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Impact of hypoxia and AMPK on CFTR-mediated bicarbonate secretion in human cholangiocyte organoids von Roos, Floris J M, Bijvelds, Marcel J C, Verstegen, Monique M A, Roest, Henk P, Metselaar, Herold J, Polak, Wojciech G, Jonge, Hugo R de, IJzermans, Jan N M, Laan, Luc J W van der

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A functional CFTR assay using primary cystic fibrosis intestinal organoids von Dekkers, Johanna F, Wiegerinck, Caroline L, de Jonge, Hugo R, Bronsveld, Inez, Janssens, Hettie M, de Winter-de Groot, Karin M, Brandsma, Arianne M, de Jong, Nienke W M, Bijvelds, Marcel J C, Scholte, Bob J, Nieuwenhuis, Edward E S, van den Brink, Stieneke, Clevers, Hans, van der Ent, Cornelis K, Middendorp, Sabine, Beekman, Jeffrey M

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Mini-gut: a promising model for drug development von Yin, Yue-Bang, de Jonge, Hugo R., Wu, Xin, Yin, Yu-Long

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Rescue of murine F508del CFTR activity in native intestine by low temperature and proteasome inhibitors von Wilke, Martina, Bot, Alice, Jorna, Huub, Scholte, Bob J, de Jonge, Hugo R

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Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease von Verstegen, Monique M. A., Roos, Floris J. M., Burka, Ksenia, Gehart, Helmuth, Jager, Myrthe, de Wolf, Maaike, Bijvelds, Marcel J. C., de Jonge, Hugo R., Ardisasmita, Arif I., van Huizen, Nick A., Roest, Henk P., de Jonge, Jeroen, Koch, Michael, Pampaloni, Francesco, Fuchs, Sabine A., Schene, Imre F., Luider, Theo M., van der Doef, Hubert P. J., Bodewes, Frank A. J. A., de Kleine, Ruben H. J., Spee, Bart, Kremers, Gert-Jan, Clevers, Hans, IJzermans, Jan N. M., Cuppen, Edwin, van der Laan, Luc J. W.

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Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR von Bose, Samuel J, Bijvelds, Marcel J C, Wang, Yiting, Liu, Jia, Cai, Zhiwei, Bot, Alice G M, de Jonge, Hugo R, Sheppard, David N

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Assessing cell-specific effects of genetic variations using tRNA microarrays von Polte, Christine, Wedemeyer, Daniel, Oliver, Kathryn E, Wagner, Johannes, Bijvelds, Marcel J C, Mahoney, John, de Jonge, Hugo R, Sorscher, Eric J, Ignatova, Zoya

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Mouse models of cystic fibrosis: Phenotypic analysis and research applications von Wilke, Martina, Buijs-Offerman, Ruvalic M, Aarbiou, Jamil, Colledge, William H, Sheppard, David N, Touqui, Lhousseine, Bot, Alice, Jorna, Huub, De Jonge, Hugo R, Scholte, Bob J

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Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium von Angyal, Dora, Groeneweg, Tessa A, Leung, Anny, Desain, Max, Dulla, Kalyan, de Jonge, Hugo R, Bijvelds, Marcel J C

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Activation of Intestinal Cl− Secretion by Lubiprostone Requires the Cystic Fibrosis Transmembrane Conductance Regulator von Bijvelds, Marcel J.C, Bot, Alice G.M, Escher, Johanna C, de Jonge, Hugo R

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Folding of CFTR Is Predominantly Cotranslational von Kleizen, Bertrand, van Vlijmen, Thijs, de Jonge, Hugo R., Braakman, Ineke

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Bicarbonate Transport in Cystic Fibrosis and Pancreatitis von Angyal, Dora, Bijvelds, Marcel J C, Bruno, Marco J, Peppelenbosch, Maikel P, de Jonge, Hugo R

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Lysophosphatidic Acid Stimulates the Intestinal Brush Border Na+ /H+ Exchanger 3 and Fluid Absorption via LPA5 and NHERF2 von Lin, Songbai, Yeruva, Sunil, He, Peijian, Singh, Anurag Kumar, Zhang, Huanchun, Chen, Mingmin, Lamprecht, Georg, de Jonge, Hugo R, Tse, Ming, Donowitz, Mark, Hogema, Boris M, Chun, Jerold, Seidler, Ursula, Yun, C. Chris

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Compartmentalized Accumulation of cAMP near Complexes of Multidrug Resistance Protein 4 (MRP4) and Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Contributes to Drug-in... von Moon, Changsuk, Zhang, Weiqiang, Ren, Aixia, Arora, Kavisha, Sinha, Chandrima, Yarlagadda, Sunitha, Woodrooffe, Koryse, Schuetz, John D., Valasani, Koteswara Rao, de Jonge, Hugo R., Shanmukhappa, Shiva Kumar, Shata, Mohamed Tarek M., Buddington, Randal K., Parthasarathi, Kaushik, Naren, Anjaparavanda P.

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Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology von Zachos, Nicholas C., Kovbasnjuk, Olga, Foulke-Abel, Jennifer, In, Julie, Blutt, Sarah E., de Jonge, Hugo R., Estes, Mary K., Donowitz, Mark

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Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice von Singh, Anurag Kumar, Riederer, Brigitte, Krabbenhöft, Anja, Rausch, Brigitte, Bonhagen, Janina, Lehmann, Ulrich, de Jonge, Hugo R, Donowitz, Mark, Yun, Chris, Weinman, Edward J, Kocher, Olivier, Hogema, Boris M, Seidler, Ursula

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A Potential Treatment of Congenital Sodium Diarrhea in Patients With Activating GUCY2C Mutations von van Vugt, Anke H.M., Bijvelds, Marcel J.C., de Jonge, Hugo R., Meijsen, Kelly F., Restin, Tanja, Bryant, Manuel B., Ballauff, Antje, Koot, Bart, Müller, Thomas, Houwen, Roderick H.J., Janecke, Andreas R., Middendorp, Sabine

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Biopolymer Extracted from Anadenanthera colubrina (Red Angico Gum) Exerts Therapeutic Potential in Mice: Antidiarrheal Activity and Safety Assessment von Araújo, Thiago S L, de Oliveira, Taiane M, de Sousa, Nayara A, Souza, Luan K M, Sousa, Francisca B M, de Oliveira, Ana P, Nicolau, Lucas A D, da Silva, Alfredo A V, Araújo, Alyne R, Magalhães, Pedro J C, Vasconcelos, Daniel F P, de Jonge, Hugo R, Souza, Marcellus H L P, Silva, Durcilene A, Paula, Regina C M, Medeiros, Jand Venes R

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