Improved flow cytometric detection of minimal residual disease in childhood acute lymphoblastic leukemia von Denys, B, van der Sluijs-Gelling, A J, Homburg, C, van der Schoot, C E, de Haas, V, Philippé, J, Pieters, R, van Dongen, J J M, van der Velden, V H J

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Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target von Hartsink-Segers, S A, Zwaan, C M, Exalto, C, Luijendijk, M W J, Calvert, V S, Petricoin, E F, Evans, W E, Reinhardt, D, de Haas, V, Hedtjärn, M, Hansen, B R, Koch, T, Caron, H N, Pieters, R, Den Boer, M L

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Prevalence and prognostic value of IDH1 and IDH2 mutations in childhood AML: a study of the AML–BFM and DCOG study groups von Damm, F, Thol, F, Hollink, I, Zimmermann, M, Reinhardt, K, van den Heuvel-Eibrink, M M, Zwaan, C M, de Haas, V, Creutzig, U, Klusmann, J-H, Krauter, J, Heuser, M, Ganser, A, Reinhardt, D, Thiede, C

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Highly sensitive MRD tests for ALL based on the IKZF1 Δ3–6 microdeletion von Venn, N C, van der Velden, V H J, de Bie, M, Waanders, E, Giles, J E, Law, T, Kuiper, R P, de Haas, V, Mullighan, C G, Haber, M, Marshall, G M, MD, Norris, van Dongen, J J M, Sutton, R

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Low frequency of DNMT3A mutations in pediatric AML, and the identification of the OCI-AML3 cell line as an in vitro model von Hollink, I H I M, Feng, Q, Danen-van Oorschot, A A, Arentsen-Peters, S T C J M, Verboon, L J, Zhang, P, de Haas, V, Reinhardt, D, Creutzig, U, Trka, J, Pieters, R, van den Heuvel-Eibrink, M M, Wang, J, Zwaan, C M

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Frequency and prognostic implications of JAK 1-3 aberrations in Down syndrome acute lymphoblastic and myeloid leukemia von Blink, M, Buitenkamp, T D, van den Heuvel-Eibrink, M M, Danen-van Oorschot, A A, de Haas, V, Reinhardt, D, Klusmann, J-H, Zimmermann, M, Devidas, M, Carroll, A J, Basso, G, Pession, A, Hasle, H, Pieters, R, Rabin, K R, Izraeli, S, Zwaan, C M

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RAS pathway mutations as a predictive biomarker for treatment adaptation in pediatric B-cell precursor acute lymphoblastic leukemia von Jerchel, I S, Hoogkamer, A Q, Ariës, I M, Steeghs, E M P, Boer, J M, Besselink, N J M, Boeree, A, van de Ven, C, de Groot-Kruseman, H A, de Haas, V, Horstmann, M A, Escherich, G, Zwaan, C M, Cuppen, E, Koudijs, M J, Pieters, R, den Boer, M L

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Integration of genetics and MRD to define low risk patients with B-cell precursor acute lymphoblastic leukaemia with intermediate MRD levels at the end of induction von Moorman, Anthony V., Enshaei, Amir, Murdy, Daniel, Joy, Melvin, Boer, Judith M., den Boer, Monique L., Pieters, Rob, de Haas, Valerie, Horstmann, Martin A., Escherich, Gabriele, Johansson, Bertil, Marquart, Hanne V., Schmiegelow, Kjeld, Hancock, Jeremy, Moppett, John, Heyman, Mats

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Improved survival for children and young adolescents with acute myeloid leukemia: a Dutch study on incidence, survival and mortality von Reedijk, A. M. J., Klein, K., Coebergh, J. W. W., Kremer, L. C., Dinmohamed, A. G., de Haas, V., Versluijs, A. B., Ossenkoppele, G. J., Beverloo, H. B., Pieters, R., Zwaan, C. M., Kaspers, G. J. L., Karim-Kos, H. E.

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Safety and efficacy of a maternal vaccine for the passive protection of broiler chicks against necrotic enteritis von Crouch, C.F, Withanage, G.S.K, Haas, V. de, Francis, M.J

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miR-139-5p controls translation in myeloid leukemia through EIF4G2 von Emmrich, S, Engeland, F, El-Khatib, M, Henke, K, Obulkasim, A, Schöning, J, Katsman-Kuipers, J E, Michel Zwaan, C, Pich, A, Stary, J, Baruchel, A, de Haas, V, Reinhardt, D, Fornerod, M, van den Heuvel-Eibrink, M M, Klusmann, J H

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Despite differential gene expression profiles pediatric MDS derived mesenchymal stromal cells display functionality in vitro von Calkoen, F.G.J., Vervat, C., van Pel, M., de Haas, V., Vijfhuizen, L.S., Eising, E., Kroes, W.G.M., 't Hoen, P.A.C., van den Heuvel-Eibrink, M.M., Egeler, R.M., van Tol, M.J.D., Ball, L.M.

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miR-9 is a tumor suppressor in pediatric AML with t(8;21) von Emmrich, S, Katsman-Kuipers, J E, Henke, K, Khatib, M E, Jammal, R, Engeland, F, Dasci, F, Zwaan, C M, den Boer, M L, Verboon, L, Stary, J, Baruchel, A, de Haas, V, Danen-van Oorschot, A A, Fornerod, M, Pieters, R, Reinhardt, D, Klusmann, J H, van den Heuvel-Eibrink, M M

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Population Pharmacokinetics and Pharmacodynamics of Ciprofloxacin Prophylaxis in Pediatric Acute Lymphoblastic Leukemia Patients von Sassen, S D T, Mathôt, R A A, Pieters, R, de Haas, V, Kaspers, G J L, van den Bos, C, Tissing, W J E, te Loo, D M W W, Bierings, M B, van Westreenen, M, van der Sluis, I M, Zwaan, C M

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Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia von Waanders, E, van der Velden, V H J, van der Schoot, C E, van Leeuwen, F N, van Reijmersdal, S V, de Haas, V, Veerman, A J, van Kessel, A Geurts, Hoogerbrugge, P M, Kuiper, R P, van Dongen, J J M

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Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations von Buitenkamp, T D, Pieters, R, Gallimore, N E, van der Veer, A, Meijerink, J P P, Beverloo, H B, Zimmermann, M, de Haas, V, Richards, S M, Vora, A J, Mitchell, C D, Russell, L J, Schwab, C, Harrison, C J, Moorman, A V, van den Heuvel-Eibrink, M M, den Boer, M L, Zwaan, C M

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High-risk childhood acute lymphoblastic leukemia in first remission treated with novel intensive chemotherapy and allogeneic transplantation von Marshall, G M, Dalla Pozza, L, Sutton, R, Ng, A, de Groot-Kruseman, H A, van der Velden, V H, Venn, N C, van den Berg, H, de Bont, E S J M, Maarten Egeler, R, Hoogerbrugge, P M, Kaspers, G J L, Bierings, M B, van der Schoot, E, van Dongen, J, Law, T, Cross, S, Mueller, H, de Haas, V, Haber, M, Révész, T, Alvaro, F, Suppiah, R, Norris, M D, Pieters, R

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Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia von BALGOBIND, Brian V, HOLLINK, Iris H. I. M, ZEMANOVA, Zuzana, STARY, Jan, CAYUELA, Jean-Michel, BARUCHEL, Andre, CREUTZIG, Ursula, REINHARDT, Dirk, PIETERS, Rob, MICHEL ZWAAN, C, VAN DEN HEUVEL-EIBRINK, Marry M, ARENTSEN-PETERS, Susan T. C. J. M, ZIMMERMANN, Martin, HARBOTT, Jochen, BERNA BEVERLOO, H, VON BERGH, Anne R. M, CLOOS, Jacqueline, KASPERS, Gertjan J. L, DE HAAS, Valerie

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Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors von Niewerth, Denise, Franke, Niels E, Jansen, Gerrit, Assaraf, Yehuda G, van Meerloo, Johan, Kirk, Christopher J, Degenhardt, Jeremiah, Anderl, Janet, Schimmer, Aaron D, Zweegman, Sonja, de Haas, Valerie, Horton, Terzah M, Kaspers, Gertjan J L, Cloos, Jacqueline

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Insights in dynamic kinome reprogramming as a consequence of MEK inhibition in MLL-rearranged AML von Kampen, K R, ter Elst, A, Mahmud, H, Scherpen, F J G, Diks, S H, Peppelenbosch, M P, de Haas, V, Guryev, V, de Bont, E S J M

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