Model‐Based Characterization of the Pharmacokinetics of Pembrolizumab: A Humanized Anti–PD‐1 Monoclonal Antibody in Advanced Solid Tumors von Ahamadi, M, Freshwater, T, Prohn, M, Li, CH, de Alwis, DP, de Greef, R, Elassaiss‐Schaap, J, Kondic, A, Stone, JA

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Translational Pharmacokinetic/Pharmacodynamic Modeling of Tumor Growth Inhibition Supports Dose‐Range Selection of the Anti–PD‐1 Antibody Pembrolizumab von Lindauer, A, Valiathan, CR, Mehta, K, Sriram, V, de Greef, R, Elassaiss‐Schaap, J, de Alwis, DP

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Using Model‐Based “Learn and Confirm” to Reveal the Pharmacokinetics‐Pharmacodynamics Relationship of Pembrolizumab in the KEYNOTE‐001 Trial von Elassaiss‐Schaap, J, Rossenu, S, Lindauer, A, Kang, SP, de Greef, R, Sachs, JR, de Alwis, DP

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Population Pharmacokinetic/Pharmacodynamic Modeling of Tumor Size Dynamics in Pembrolizumab‐Treated Advanced Melanoma von Chatterjee, MS, Elassaiss‐Schaap, J, Lindauer, A, Turner, DC, Sostelly, A, Freshwater, T, Mayawala, K, Ahamadi, M, Stone, JA, Greef, R, Kondic, AG, Alwis, DP

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Modeling and Simulation of the Time Course of Asenapine Exposure Response and Dropout Patterns in Acute Schizophrenia von Friberg, LE, Greef, R, Kerbusch, T, Karlsson, MO

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Comparison of QTc Data Analysis Methods Recommended by the ICH E14 Guidance and Exposure-Response Analysis: Case Study of a Thorough QT Study of Asenapine von Chapel, S, Hutmacher, M M, Bockbrader, H, Greef, R, Lalonde, R L

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Dose Selection of Corifollitropin Alfa by Modeling and Simulation in Controlled Ovarian Stimulation von Greef, R, Zandvliet, A S, Haan, A F J, IJzerman‐Boon, P C, Marintcheva‐Petrova, M, Mannaerts, B M J L

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Pembrolizumab: Role of Modeling and Simulation in Bringing a Novel Immunotherapy to Patients With Melanoma von de Greef, R, Elassaiss‐Schaap, J, Chatterjee, M, Turner, DC, Ahamadi, M, Forman, M, Cutler, D, de Alwis, DP, Kondic, A, Stone, J

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The pharmacokinetics of fondaparinux sodium in healthy volunteers von Donat, François, Duret, Jean Pierre, Santoni, Alix, Cariou, Roger, Necciari, José, Magnani, Harry, de Greef, Rik

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3344 Relationship between pembrolizumab exposure and efficacy/safety in 1016 patients (pts) with advanced or metastatic melanoma von Kang, S.P, Chatterjee, M, Ahamadi, M, De Alwis, D, De Greef, R, Elassaiss-Schaap, J, Freshwater, T, Mayawala, K, Stone, J, Ebbinghaus, S, Turner, D, Kondic, A

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P.3.c.056 Population pharmacokinetics of asenapine in patients with schizophrenia or bipolar disorder von Prohn, M, De Greef, R, Chapel, S, Kerbusch, T

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Intellectual disability healthcare in Australia: Progress, challenges, and future directions von Brooker, K. S., De Greef, R., Trollor, J. N., Franklin, C. S., Weise, J.

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P.1.d.009 Asenapine: a translational analysis of receptor occupancy in human and rat brain with therapeutic implications von Henry, B, Grimwood, S, de Greef, R, Shahid, M

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P.3.c.056 Dose selection of asenapine: application of models based on D2 occupancy to predict efficacy and safety von de Greef, R, Maloney, A, Olsson-Gisleskog, P, Prins, K, Schoemaker, J, Panagides, J

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Electrochemical dissolution of tin in methanesulphonic acid solutions von DE GREEF, R. A. T, JANSSEN, L. J. J

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Absence of interaction of fondaparinux sodium with aspirin and piroxicam in healthy male volunteers von Ollier, Céline, Faaij, Richard A, Santoni, Alix, Duvauchelle, Thierry, van Haard, Paul M M, Schoemaker, Rik C, Cohen, Adam F, de Greef, Rik, Burggraaf, Jacobus

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Asenapine pharmacokinetics and tolerability in a pediatric population von Dogterom, Peter, Riesenberg, Robert, de Greef, Rik, Dennie, Justin, Johnson, Martin, Pilla Reddy, Venkatesh, Miltenburg, André Mm, Findling, Robert L, Jakate, Abhijeet, Carrothers, Timothy J, Troyer, Matthew D

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Using Model-Based “Learn and Confirm” to Reveal the Pharmacokinetics-Pharmacodynamics Relationship of Pembrolizumab in the KEYNOTE-001 Trial: Modeling of the PK/PD of Pembro in KEY... von Elassaiss-Schaap, J, Rossenu, S, Lindauer, A, Kang, SP, de Greef, R, Sachs, JR, de Alwis, DP

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Translational Pharmacokinetic/Pharmacodynamic Modeling of Tumor Growth Inhibition Supports Dose-Range Selection of the Anti-PD-1 Antibody Pembrolizumab: Translational Pharmacokinet... von Lindauer, A, Valiathan, CR, Mehta, K, Sriram, V, de Greef, R, Elassaiss-Schaap, J, de Alwis, DP

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Pembrolizumab: Role of Modeling and Simulation in Bringing a Novel Immunotherapy to Patients With Melanoma: Modeling and Simulation of Pembrolizumab von de Greef, R, Elassaiss-Schaap, J, Chatterjee, M, Turner, DC, Ahamadi, M, Forman, M, Cutler, D, de Alwis, DP, Kondic, A, Stone, J

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