Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm von Dziedzicka, Dominika, Tewary, Mukul, Keller, Alexander, Tilleman, Laurentijn, Prochazka, Laura, Östblom, Joel, Couvreu De Deckersberg, Edouard, Markouli, Christina, Franck, Silvie, Van Nieuwerburgh, Filip, Spits, Claudia, Zandstra, Peter W., Sermon, Karen, Geens, Mieke

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Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing von Franck, Silvie, Couvreu De Deckersberg, Edouard, Bubenik, Jodi L, Markouli, Christina, Barbé, Lise, Allemeersch, Joke, Hilven, Pierre, Duqué, Geoffrey, Swanson, Maurice S, Gheldof, Alexander, Spits, Claudia, Sermon, Karen D

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Mitochondrial DNA variants segregate during human preimplantation development into genetically different cell lineages that are maintained postnatally von Mertens, Joke, Regin, Marius, De Munck, Neelke, Deckersberg, Edouard Couvreu, Belva, Florence, Sermon, Karen, Tournaye, Herman, Blockeel, Christophe, Van de Velde, Hilde, Spits, Claudia

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SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss von Lei, Yingnan, Al Delbany, Diana, Krivec, Nuša, Regin, Marius, Couvreu de Deckersberg, Edouard, Janssens, Charlotte, Ghosh, Manjusha, Sermon, Karen, Spits, Claudia

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Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos von Regin, Marius, Lei, Yingnan, Couvreu De Deckersberg, Edouard, Janssens, Charlotte, Huyghebaert, Anfien, Guns, Yves, Verdyck, Pieter, Verheyen, Greta, Van de Velde, Hilde, Sermon, Karen, Spits, Claudia

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Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity von Krivec, Nuša, de Deckersberg, Edouard Couvreu, Lei, Yingnan, Delbany, Diana Al, Regin, Marius, Verhulst, Stefaan, van Grunsven, Leo A., Sermon, Karen, Spits, Claudia

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Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight von Mertens, Joke, Belva, Florence, van Montfoort, Aafke P. A., Regin, Marius, Zambelli, Filippo, Seneca, Sara, Couvreu de Deckersberg, Edouard, Bonduelle, Maryse, Tournaye, Herman, Stouffs, Katrien, Barbé, Kurt, Smeets, Hubert J. M., Van de Velde, Hilde, Sermon, Karen, Blockeel, Christophe, Spits, Claudia

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Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm von Dziedzicka, Dominika, Tewary, Mukul, Keller, Alexander, Tilleman, Laurentijn, Prochazka, Laura, Ostblom, Joel, De Deckersberg, Edouard Couvreu, Markouli, Christina, Franck, Silvie, Van Nieuwerburgh, Filip, Spits, Claudia, Zandstra, Peter W, Sermon, Karen, Geens, Mieke

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Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing von Franck, Silvie, De Deckersberg, Edouard Couvreu, Bubenik, Jodi L, Markouli, Christina, Barbe, Lise, Allemeersch, Joke, Hilven, Pierre, Duque, Geoffrey, Swanson, Maurice S, Gheldof, Alexander, Spits, Claudia, Sermon, Karen D

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Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos von Regin, Marius, Lei, Yingnan, Couvreu de Deckersberg, Edouard, Guns, Yves, Verdyck, Pieter, Verheyen, Greta, Van de Velde, Hilde, Sermon, Karen, Spits, Claudia

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