AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival von Kishton, Rigel J., Barnes, Carson E., Nichols, Amanda G., Cohen, Sivan, Gerriets, Valerie A., Siska, Peter J., Macintyre, Andrew N., Goraksha-Hicks, Pankuri, de Cubas, Aguirre A., Liu, Tingyu, Warmoes, Marc O., Abel, E. Dale, Yeoh, Allen Eng Juh, Gershon, Timothy R., Rathmell, W. Kimryn, Richards, Kristy L., Locasale, Jason W., Rathmell, Jeffrey C.

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Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism von Johnson, Marc O., Wolf, Melissa M., Madden, Matthew Z., Andrejeva, Gabriela, Sugiura, Ayaka, Contreras, Diana C., Maseda, Damian, Liberti, Maria V., Paz, Katelyn, Kishton, Rigel J., Johnson, Matthew E., de Cubas, Aguirre A., Wu, Pingsheng, Li, Gongbo, Zhang, Yongliang, Newcomb, Dawn C., Wells, Andrew D., Restifo, Nicholas P., Rathmell, W. Kimryn, Locasale, Jason W., Davila, Marco L., Blazar, Bruce R., Rathmell, Jeffrey C.

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SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma von Chiang, Yun-Chen, Park, In-Young, Terzo, Esteban A, Tripathi, Durga Nand, Mason, Frank M, Fahey, Catherine C, Karki, Menuka, Shuster, Charles B, Sohn, Bo-Hwa, Chowdhury, Pratim, Powell, Reid T, Ohi, Ryoma, Tsai, Yihsuan S, de Cubas, Aguirre A, Khan, Abid, Davis, Ian J, Strahl, Brian D, Parker, Joel S, Dere, Ruhee, Walker, Cheryl L, Rathmell, W Kimryn

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Whole-Exome Sequencing Identifies MDH2 as a New Familial Paraganglioma Gene von Cascón, Alberto, Comino-Méndez, Iñaki, Currás-Freixes, María, de Cubas, Aguirre A., Contreras, Laura, Richter, Susan, Peitzsch, Mirko, Mancikova, Veronika, Inglada-Pérez, Lucía, Pérez-Barrios, Andrés, Calatayud, María, Azriel, Sharona, Villar-Vicente, Rosa, Aller, Javier, Setién, Fernando, Moran, Sebastian, Garcia, Juan F., Río-Machín, Ana, Letón, Rocío, Gómez-Graña, Álvaro, Apellániz-Ruiz, María, Roncador, Giovanna, Esteller, Manel, Rodríguez-Antona, Cristina, Satrústegui, Jorgina, Eisenhofer, Graeme, Urioste, Miguel, Robledo, Mercedes

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Tumoral EPAS1 (HIF2A) mutations explain sporadic pheochromocytoma and paraganglioma in the absence of erythrocytosis von Comino-Méndez, Iñaki, de Cubas, Aguirre A, Bernal, Carmen, Álvarez-Escolá, Cristina, Sánchez-Malo, Carolina, Ramírez-Tortosa, César L, Pedrinaci, Susana, Rapizzi, Elena, Ercolino, Tonino, Bernini, Giampaolo, Bacca, Alessandra, Letón, Rocío, Pita, Guillermoó, Alonso, María R, Leandro-García, Luis J, Gómez-Graña, Alvaro, Inglada-Pérez, Lucía, Mancikova, Veronika, Rodríguez-Antona, Cristina, Mannelli, Massimo, Robledo, Mercedes, Cascón, Alberto

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DNA Methylation Profiling in Pheochromocytoma and Paraganglioma Reveals Diagnostic and Prognostic Markers von de Cubas, Aguirre A, Korpershoek, Esther, Inglada-Pérez, Lucia, Letouzé, Eric, Currás-Freixes, Maria, Fernández, Agustin F, Comino-Méndez, Iñaki, Schiavi, Francesca, Mancikova, Veronika, Eisenhofer, Graeme, Mannelli, Massimo, Opocher, Guiseppe, Timmers, Henri, Beuschlein, Felix, de Krijger, Ronald, Cascon, Alberto, Rodríguez-Antona, Cristina, Fraga, Mario F, Favier, Judith, Gimenez-Roqueplo, Anne-Paule, Robledo, Mercedes

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Epigenetic modifiers: activities in renal cell carcinoma von de Cubas, Aguirre A., Rathmell, W. Kimryn

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Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma von Smith, Christof C, Beckermann, Kathryn E, Bortone, Dante S, De Cubas, Aguirre A, Bixby, Lisa M, Lee, Samuel J, Panda, Anshuman, Ganesan, Shridar, Bhanot, Gyan, Wallen, Eric M, Milowsky, Matthew I, Kim, William Y, Rathmell, W Kimryn, Swanstrom, Ronald, Parker, Joel S, Serody, Jonathan S, Selitsky, Sara R, Vincent, Benjamin G

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Foxp3 and Toll-like receptor signaling balance T reg cell anabolic metabolism for suppression von Gerriets, Valerie A, Kishton, Rigel J, Johnson, Marc O, Cohen, Sivan, Siska, Peter J, Nichols, Amanda G, Warmoes, Marc O, de Cubas, Aguirre A, MacIver, Nancie J, Locasale, Jason W, Turka, Laurence A, Wells, Andrew D, Rathmell, Jeffrey C

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High-affinity chimeric antigen receptor signaling induces an inflammatory program in human regulatory T cells von Cochrane, Russell W., Robino, Rob A., Granger, Bryan, Allen, Eva, Vaena, Silvia, Romeo, Martin J., de Cubas, Aguirre A., Berto, Stefano, Ferreira, Leonardo M.R.

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DNA methylation profiling of well‐differentiated thyroid cancer uncovers markers of recurrence free survival von Mancikova, Veronika, Buj, Raquel, Castelblanco, Esmeralda, Inglada‐Pérez, Lucía, Diez, Anna, Cubas, Aguirre A., Curras‐Freixes, Maria, Maravall, Francisco Xavier, Mauricio, Didac, Matias‐Guiu, Xavier, Puig‐Domingo, Manel, Capel, Ismael, Bella, María Rosa, Lerma, Enrique, Castella, Eva, Reverter, Jordi Lluis, Peinado, Miguel Ángel, Jorda, Mireia, Robledo, Mercedes

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Immunogenicity in renal cell carcinoma: shifting focus to alternative sources of tumour-specific antigens von Wolf, Melissa M., Rathmell, W. Kimryn, de Cubas, Aguirre A.

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Germline mutations in FH confer predisposition to malignant pheochromocytomas and paragangliomas von Castro-Vega, Luis Jaime, Buffet, Alexandre, De Cubas, Aguirre A, Cascón, Alberto, Menara, Mélanie, Khalifa, Emmanuel, Amar, Laurence, Azriel, Sharona, Bourdeau, Isabelle, Chabre, Olivier, Currás-Freixes, Maria, Franco-Vidal, Valérie, Guillaud-Bataille, Marine, Simian, Christophe, Morin, Aurélie, Letón, Rocío, Gómez-Graña, Alvaro, Pollard, Patrick J, Rustin, Pierre, Robledo, Mercedes, Favier, Judith, Gimenez-Roqueplo, Anne-Paule

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Krebs Cycle Metabolite Profiling for Identification and Stratification of Pheochromocytomas/Paragangliomas due to Succinate Dehydrogenase Deficiency von Richter, Susan, Peitzsch, Mirko, Rapizzi, Elena, Lenders, Jacques W, Qin, Nan, de Cubas, Aguirre A, Schiavi, Francesca, Rao, Jyotsna U, Beuschlein, Felix, Quinkler, Marcus, Timmers, Henri J, Opocher, Giuseppe, Mannelli, Massimo, Pacak, Karel, Robledo, Mercedes, Eisenhofer, Graeme

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Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene von Cascón, Alberto, Comino-Méndez, Iñaki, Currás-Freixes, María, de Cubas, Aguirre A, Contreras, Laura, Richter, Susan, Peitzsch, Mirko, Mancikova, Veronika, Inglada-Pérez, Lucía, Pérez-Barrios, Andrés, Calatayud, María, Azriel, Sharona, Villar-Vicente, Rosa, Aller, Javier, Setién, Fernando, Moran, Sebastian, Garcia, Juan F, Río-Machín, Ana, Letón, Rocío, Gómez-Graña, Álvaro, Apellániz-Ruiz, María, Roncador, Giovanna, Esteller, Manel, Rodríguez-Antona, Cristina, Satrústegui, Jorgina, Eisenhofer, Graeme, Urioste, Miguel, Robledo, Mercedes

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Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma von Robledo, Mercedes, Cascón, Alberto, Comino-Méndez, Iñaki, Gracia-Aznárez, Francisco J, Schiavi, Francesca, Landa, Iñigo, Leandro-García, Luis J, Letón, Rocío, Honrado, Emiliano, Ramos-Medina, Rocío, Caronia, Daniela, Pita, Guillermo, Gómez-Graña, Álvaro, de Cubas, Aguirre A, Inglada-Pérez, Lucía, Maliszewska, Agnieszka, Taschin, Elisa, Bobisse, Sara, Pica, Giuseppe, Loli, Paola, Hernández-Lavado, Rafael, Díaz, José A, Gómez-Morales, Mercedes, González-Neira, Anna, Roncador, Giovanna, Rodríguez-Antona, Cristina, Benítez, Javier, Mannelli, Massimo, Opocher, Giuseppe

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Epigenetic Mutation of the Succinate Dehydrogenase C Promoter in a Patient With Two Paragangliomas von Richter, Susan, Klink, Barbara, Nacke, Brit, de Cubas, Aguirre A, Mangelis, Anastasios, Rapizzi, Elena, Meinhardt, Matthias, Skondra, Christina, Mannelli, Massimo, Robledo, Mercedes, Menschikowski, Mario, Eisenhofer, Graeme

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Endogenous retrovirus expression is associated with response to immune checkpoint blockade in clear cell renal cell carcinoma von Panda, Anshuman, de Cubas, Aguirre A, Stein, Mark, Riedlinger, Gregory, Kra, Joshua, Mayer, Tina, Smith, Christof C, Vincent, Benjamin G, Serody, Jonathan S, Beckermann, Kathryn E, Ganesan, Shridar, Bhanot, Gyan, Rathmell, W Kimryn

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HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer von Ferretti, Giulia D. S., Quaas, Colleen E., Bertolini, Irene, Zuccotti, Alessandro, Saatci, Ozge, Kashatus, Jennifer A., Sharmin, Salma, Lu, David Y., Poli, Adi Narayana Reddy, Quesnelle, Abigail F., Rodriguez-Blanco, Jezabel, de Cubas, Aguirre A., Hobbs, G. Aaron, Liu, Qin, O’Bryan, John P., Salvino, Joseph M., Kashatus, David F., Sahin, Ozgur, Barnoud, Thibaut

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DNA hypomethylation promotes transposable element expression and activation of immune signaling in renal cell cancer von de Cubas, Aguirre A, Dunker, William, Zaninovich, Andrew, Hongo, Rachel A, Bhatia, Anuj, Panda, Anshuman, Beckermann, Kathryn E, Bhanot, Gyan, Ganesan, Shridar, Karijolich, John, Rathmell, W Kimryn

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