Effects of Intermittent Fasting on Health, Aging, and Disease von de Cabo, Rafael, Mattson, Mark P

Volltext

A time to fast von Di Francesco, Andrea, Di Germanio, Clara, Bernier, Michel, de Cabo, Rafael

Volltext

The Search for Antiaging Interventions: From Elixirs to Fasting Regimens von de Cabo, Rafael, Carmona-Gutierrez, Didac, Bernier, Michel, Hall, Michael N., Madeo, Frank

Volltext

The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance von Lee, Changhan, Zeng, Jennifer, Drew, Brian G., Sallam, Tamer, Martin-Montalvo, Alejandro, Wan, Junxiang, Kim, Su-Jeong, Mehta, Hemal, Hevener, Andrea L., de Cabo, Rafael, Cohen, Pinchas

Volltext

Metformin improves healthspan and lifespan in mice von Martin-Montalvo, Alejandro, Mercken, Evi M., Mitchell, Sarah J., Palacios, Hector H., Mote, Patricia L., Scheibye-Knudsen, Morten, Gomes, Ana P., Ward, Theresa M., Minor, Robin K., Blouin, Marie-José, Schwab, Matthias, Pollak, Michael, Zhang, Yongqing, Yu, Yinbing, Becker, Kevin G., Bohr, Vilhelm A., Ingram, Donald K., Sinclair, David A., Wolf, Norman S., Spindler, Stephen R., Bernier, Michel, de Cabo, Rafael

Volltext

Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise von Mera, Paula, Laue, Kathrin, Ferron, Mathieu, Confavreux, Cyril, Wei, Jianwen, Galán-Díez, Marta, Lacampagne, Alain, Mitchell, Sarah J., Mattison, Julie A., Chen, Yun, Bacchetta, Justine, Szulc, Pawel, Kitsis, Richard N., de Cabo, Rafael, Friedman, Richard A., Torsitano, Christopher, McGraw, Timothy E., Puchowicz, Michelle, Kurland, Irwin, Karsenty, Gerard

Volltext

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging von Gomes, Ana P., Price, Nathan L., Ling, Alvin J.Y., Moslehi, Javid J., Montgomery, Magdalene K., Rajman, Luis, White, James P., Teodoro, João S., Wrann, Christiane D., Hubbard, Basil P., Mercken, Evi M., Palmeira, Carlos M., de Cabo, Rafael, Rolo, Anabela P., Turner, Nigel, Bell, Eric L., Sinclair, David A.

Volltext

Reduced Expression of MYC Increases Longevity and Enhances Healthspan von Hofmann, Jeffrey W., Zhao, Xiaoai, De Cecco, Marco, Peterson, Abigail L., Pagliaroli, Luca, Manivannan, Jayameenakshi, Hubbard, Gene B., Ikeno, Yuji, Zhang, Yongqing, Feng, Bin, Li, Xiaxi, Serre, Thomas, Qi, Wenbo, Van Remmen, Holly, Miller, Richard A., Bath, Kevin G., de Cabo, Rafael, Xu, Haiyan, Neretti, Nicola, Sedivy, John M.

Volltext

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function von Price, Nathan L., Gomes, Ana P., Ling, Alvin J.Y., Duarte, Filipe V., Martin-Montalvo, Alejandro, North, Brian J., Agarwal, Beamon, Ye, Lan, Ramadori, Giorgio, Teodoro, Joao S., Hubbard, Basil P., Varela, Ana T., Davis, James G., Varamini, Behzad, Hafner, Angela, Moaddel, Ruin, Rolo, Anabela P., Coppari, Roberto, Palmeira, Carlos M., de Cabo, Rafael, Baur, Joseph A., Sinclair, David A.

Volltext

Daily caloric restriction limits tumor growth more effectively than caloric cycling regardless of dietary composition von Pomatto-Watson, Laura C. D., Bodogai, Monica, Bosompra, Oye, Kato, Jonathan, Wong, Sarah, Carpenter, Melissa, Duregon, Eleonora, Chowdhury, Dolly, Krishna, Priya, Ng, Sandy, Ragonnaud, Emeline, Salgado, Roberto, Gonzalez Ericsson, Paula, Diaz-Ruiz, Alberto, Bernier, Michel, Price, Nathan L., Biragyn, Arya, Longo, Valter D., de Cabo, Rafael

Volltext

A High-Fat Diet and NAD+ Activate Sirt1 to Rescue Premature Aging in Cockayne Syndrome von Scheibye-Knudsen, Morten, Mitchell, Sarah J., Fang, Evandro F., Iyama, Teruaki, Ward, Theresa, Wang, James, Dunn, Christopher A., Singh, Nagendra, Veith, Sebastian, Hasan-Olive, Md Mahdi, Mangerich, Aswin, Wilson, Mark A., Mattson, Mark P., Bergersen, Linda H., Cogger, Victoria C., Warren, Alessandra, Le Couteur, David G., Moaddel, Ruin, Wilson, David M., Croteau, Deborah L., de Cabo, Rafael, Bohr, Vilhelm A.

Volltext

Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors von Kim, Ha-Neui, Ponte, Filipa, Nookaew, Intawat, Ucer Ozgurel, Serra, Marques-Carvalho, Adriana, Iyer, Srividhya, Warren, Aaron, Aykin-Burns, Nukhet, Krager, Kimberly, Sardao, Vilma A., Han, Li, de Cabo, Rafael, Zhao, Haibo, Jilka, Robert L., Manolagas, Stavros C., Almeida, Maria

Volltext

The SIRT1 Activator SRT1720 Extends Lifespan and Improves Health of Mice Fed a Standard Diet von Mitchell, Sarah J., Martin-Montalvo, Alejandro, Mercken, Evi M., Palacios, Hector H., Ward, Theresa M., Abulwerdi, Gelareh, Minor, Robin K., Vlasuk, George P., Ellis, James L., Sinclair, David A., Dawson, John, Allison, David B., Zhang, Yongqing, Becker, Kevin G., Bernier, Michel, de Cabo, Rafael

Volltext

Resveratrol Prevents High Fat/Sucrose Diet-Induced Central Arterial Wall Inflammation and Stiffening in Nonhuman Primates von Mattison, Julie A., Wang, Mingyi, Bernier, Michel, Zhang, Jing, Park, Sung-Soo, Maudsley, Stuart, An, Steven S., Santhanam, Lakshmi, Martin, Bronwen, Faulkner, Shakeela, Morrell, Christopher, Baur, Joseph A., Peshkin, Leonid, Sosnowska, Danuta, Csiszar, Anna, Herbert, Richard L., Tilmont, Edward M., Ungvari, Zoltan, Pearson, Kevin J., Lakatta, Edward G., de Cabo, Rafael

Volltext

Prolonged metformin treatment leads to reduced transcription of Nrf2 and neurotrophic factors without cognitive impairment in older C57BL/6J mice von Allard, Joanne S., Perez, Evelyn J., Fukui, Koji, Carpenter, Priscilla, Ingram, Donald K., Cabo, Rafael de

Volltext

Hepatic HuR modulates lipid homeostasis in response to high-fat diet von Zhang, Zhuojun, Zong, Chen, Jiang, Mingyang, Hu, Han, Cheng, Xiaolei, Ni, Juhua, Yi, Xia, Jiang, Bin, Tian, Feng, Chang, Ming-Wen, Su, Wen, Zhu, Lijun, Li, Jinfan, Xiang, Xueping, Miao, Congxiu, Gorospe, Myriam, de Cabo, Rafael, Dou, Yali, Ju, Zhenyu, Yang, Jichun, Jiang, Changtao, Yang, Zhongzhou, Wang, Wengong

Volltext

Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice von Solon-Biet, Samantha M., Mitchell, Sarah J., Coogan, Sean C.P., Cogger, Victoria C., Gokarn, Rahul, McMahon, Aisling C., Raubenheimer, David, de Cabo, Rafael, Simpson, Stephen J., Le Couteur, David G.

Volltext

A Regulatory Role for MicroRNA 33 in Controlling Lipid Metabolism Gene Expression von Goedeke, Leigh, Vales-Lara, Frances M, Fenstermaker, Michael, Cirera-Salinas, Daniel, Chamorro-Jorganes, Aranzazu, Ramírez, Cristina M, Mattison, Julie A, de Cabo, Rafael, Suárez, Yajaira, Fernández-Hernando, Carlos

Volltext

Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway von Ashrafian, Houman, Czibik, Gabor, Bellahcene, Mohamed, Aksentijević, Dunja, Smith, Anthony C., Mitchell, Sarah J., Dodd, Michael S., Kirwan, Jennifer, Byrne, Jonathan J., Ludwig, Christian, Isackson, Henrik, Yavari, Arash, Støttrup, Nicolaj B., Contractor, Hussain, Cahill, Thomas J., Sahgal, Natasha, Ball, Daniel R., Birkler, Rune I.D., Hargreaves, Iain, Tennant, Daniel A., Land, John, Lygate, Craig A., Johannsen, Mogens, Kharbanda, Rajesh K., Neubauer, Stefan, Redwood, Charles, de Cabo, Rafael, Ahmet, Ismayil, Talan, Mark, Günther, Ulrich L., Robinson, Alan J., Viant, Mark R., Pollard, Patrick J., Tyler, Damian J., Watkins, Hugh

Volltext

Resveratrol Improves Adipose Insulin Signaling and Reduces the Inflammatory Response in Adipose Tissue of Rhesus Monkeys on High-Fat, High-Sugar Diet von Jimenez-Gomez, Yolanda, Mattison, Julie A., Pearson, Kevin J., Martin-Montalvo, Alejandro, Palacios, Hector H., Sossong, Alex M., Ward, Theresa M., Younts, Caitlin M., Lewis, Kaitlyn, Allard, Joanne S., Longo, Dan L., Belman, Jonathan P., Malagon, Maria M., Navas, Placido, Sanghvi, Mitesh, Moaddel, Ruin, Tilmont, Edward M., Herbert, Richard L., Morrell, Christopher H., Egan, Josephine M., Baur, Joseph A., Ferrucci, Luigi, Bogan, Jonathan S., Bernier, Michel, de Cabo, Rafael

Volltext