Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation von Coni, Sonia, Serrao, Silvia Maria, Yurtsever, Zuleyha Nihan, Di Magno, Laura, Bordone, Rosa, Bertani, Camilla, Licursi, Valerio, Ianniello, Zaira, Infante, Paola, Moretti, Marta, Petroni, Marialaura, Guerrieri, Francesca, Fatica, Alessandro, Macone, Alberto, De Smaele, Enrico, Di Marcotullio, Lucia, Giannini, Giuseppe, Maroder, Marella, Agostinelli, Enzo, Canettieri, Gianluca

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Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth von D’Amico, Davide, Antonucci, Laura, Di Magno, Laura, Coni, Sonia, Sdruscia, Giulia, Macone, Alberto, Miele, Evelina, Infante, Paola, Di Marcotullio, Lucia, De Smaele, Enrico, Ferretti, Elisabetta, Ciapponi, Laura, Giangaspero, Felice, Yates, John R., Agostinelli, Enzo, Cardinali, Beatrice, Screpanti, Isabella, Gulino, Alberto, Canettieri, Gianluca

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Hypoxia, endoplasmic reticulum stress and chemoresistance: dangerous liaisons von Akman, Muhlis, Belisario, Dimas Carolina, Salaroglio, Iris Chiara, Kopecka, Joanna, Donadelli, Massimo, De Smaele, Enrico, Riganti, Chiara

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The emerging role of the KCTD proteins in cancer von Angrisani, Annapaola, Di Fiore, Annamaria, De Smaele, Enrico, Moretti, Marta

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MicroRNAs as biomarkers for CNS cancer and other disorders von De Smaele, Enrico, Ferretti, Elisabetta, Gulino, Alberto

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Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance von Belisario, Dimas Carolina, Kopecka, Joanna, Pasino, Martina, Akman, Muhlis, De Smaele, Enrico, Donadelli, Massimo, Riganti, Chiara

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Functional cooperation between ASK1 and p21Waf1/Cip1 in the balance of cell-cycle arrest, cell death and tumorigenesis of stressed keratinocytes von De Blasio, Carlo, Verma, Nagendra, Moretti, Marta, Cialfi, Samantha, Zonfrilli, Azzurra, Franchitto, Matteo, Truglio, Federica, De Smaele, Enrico, Ichijo, Hidenori, Naguro, Isao, Screpanti, Isabella, Talora, Claudio

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Hedgehog-GLI signalling promotes chemoresistance through the regulation of ABC transporters in colorectal cancer cells von Po, Agnese, Citarella, Anna, Catanzaro, Giuseppina, Besharat, Zein Mersini, Trocchianesi, Sofia, Gianno, Francesca, Sabato, Claudia, Moretti, Marta, De Smaele, Enrico, Vacca, Alessandra, Fiori, Micol Eleonora, Ferretti, Elisabetta

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Che-1/AATF binds to RNA polymerase I machinery and sustains ribosomal RNA gene transcription von Sorino, Cristina, Catena, Valeria, Bruno, Tiziana, De Nicola, Francesca, Scalera, Stefano, Bossi, Gianluca, Fabretti, Francesca, Mano, Miguel, De Smaele, Enrico, Fanciulli, Maurizio, Iezzi, Simona

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Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis von Infante, Paola, Faedda, Roberta, Bernardi, Flavia, Bufalieri, Francesca, Lospinoso Severini, Ludovica, Alfonsi, Romina, Mazzà, Daniela, Siler, Mariangela, Coni, Sonia, Po, Agnese, Petroni, Marialaura, Ferretti, Elisabetta, Mori, Mattia, De Smaele, Enrico, Canettieri, Gianluca, Capalbo, Carlo, Maroder, Marella, Screpanti, Isabella, Kool, Marcel, Pfister, Stefan M., Guardavaccaro, Daniele, Gulino, Alberto, Di Marcotullio, Lucia

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β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells von Miele, Evelina, Po, Agnese, Begalli, Federica, Antonucci, Laura, Mastronuzzi, Angela, Marras, Carlo Efisio, Carai, Andrea, Cucchi, Danilo, Abballe, Luana, Besharat, Zein Mersini, Catanzaro, Giuseppina, Infante, Paola, Di Marcotullio, Lucia, Canettieri, Gianluca, De Smaele, Enrico, Screpanti, Isabella, Locatelli, Franco, Ferretti, Elisabetta

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ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP von Bufalieri, Francesca, Infante, Paola, Bernardi, Flavia, Caimano, Miriam, Romania, Paolo, Moretti, Marta, Lospinoso Severini, Ludovica, Talbot, Julie, Melaiu, Ombretta, Tanori, Mirella, Di Magno, Laura, Bellavia, Diana, Capalbo, Carlo, Puget, Stéphanie, De Smaele, Enrico, Canettieri, Gianluca, Guardavaccaro, Daniele, Busino, Luca, Peschiaroli, Angelo, Pazzaglia, Simonetta, Giannini, Giuseppe, Melino, Gerry, Locatelli, Franco, Gulino, Alberto, Ayrault, Olivier, Fruci, Doriana, Di Marcotullio, Lucia

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Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module von Di Magno, Laura, Manni, Simona, Di Pastena, Fiorella, Coni, Sonia, Macone, Alberto, Cairoli, Sara, Sambucci, Manolo, Infante, Paola, Moretti, Marta, Petroni, Marialaura, Nicoletti, Carmine, Capalbo, Carlo, De Smaele, Enrico, Di Marcotullio, Lucia, Giannini, Giuseppe, Battistini, Luca, Goffredo, Bianca Maria, Iorio, Egidio, Agostinelli, Enzo, Maroder, Marella, Canettieri, Gianluca

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SCF and IL-33 regulate mouse mast cell phenotypic and functional plasticity supporting a pro-inflammatory microenvironment von Molfetta, Rosa, Lecce, Mario, Milito, Nadia D., Putro, Erisa, Pietropaolo, Giuseppe, Marangio, Caterina, Scarno, Gianluca, Moretti, Marta, De Smaele, Enrico, Santini, Tiziana, Bernardini, Giovanni, Sciumè, Giuseppe, Santoni, Angela, Paolini, Rossella

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Curcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelio... von Masuelli, Laura, Benvenuto, Monica, Di Stefano, Enrica, Mattera, Rosanna, Fantini, Massimo, De Feudis, Giuseppina, De Smaele, Enrico, Tresoldi, Ilaria, Giganti, Maria Gabriella, Modesti, Andrea, Bei, Roberto

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MicroRNA profiling in human medulloblastoma von Ferretti, Elisabetta, De Smaele, Enrico, Po, Agnese, Di Marcotullio, Lucia, Tosi, Emanuele, Espinola, Maria Salome B., Di Rocco, Concezio, Riccardi, Riccardo, Giangaspero, Felice, Farcomeni, Alessio, Nofroni, Italo, Laneve, Pietro, Gioia, Ubaldo, Caffarelli, Elisa, Bozzoni, Irene, Screpanti, Isabella, Gulino, Alberto

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Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma von Coni, Sonia, Mancuso, Anna Barbara, Di Magno, Laura, Sdruscia, Giulia, Manni, Simona, Serrao, Silvia Maria, Rotili, Dante, Spiombi, Eleonora, Bufalieri, Francesca, Petroni, Marialaura, Kusio-Kobialka, Monika, De Smaele, Enrico, Ferretti, Elisabetta, Capalbo, Carlo, Mai, Antonello, Niewiadomski, Pawel, Screpanti, Isabella, Di Marcotullio, Lucia, Canettieri, Gianluca

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Foxm1 controls a pro-stemness microRNA network in neural stem cells von Besharat, Zein Mersini, Abballe, Luana, Cicconardi, Francesco, Bhutkar, Arjun, Grassi, Luigi, Le Pera, Loredana, Moretti, Marta, Chinappi, Mauro, D’Andrea, Daniel, Mastronuzzi, Angela, Ianari, Alessandra, Vacca, Alessandra, De Smaele, Enrico, Locatelli, Franco, Po, Agnese, Miele, Evelina, Ferretti, Elisabetta

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Gli2 acetylation at lysine 757 regulates hedgehog-dependent transcriptional output by preventing its promoter occupancy von Coni, Sonia, Antonucci, Laura, D'Amico, Davide, Di Magno, Laura, Infante, Paola, De Smaele, Enrico, Giannini, Giuseppe, Di Marcotullio, Lucia, Screpanti, Isabella, Gulino, Alberto, Canettieri, Gianluca

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Combined treatment with inhibitors of ErbB Receptors and Hh signaling pathways is more effective than single treatment in reducing the growth of malignant mesothelioma both in vitr... von Bei, Roberto, Benvenuto, Monica, Focaccetti, Chiara, Fazi, Sara, Moretti, Marta, Nardozi, Daniela, Angiolini, Valentina, Ciuffa, Sara, Cifaldi, Loredana, Carrano, Raffaele, Palumbo, Camilla, Miele, Martino Tony, Bei, Riccardo, Barillari, Giovanni, Manzari, Vittorio, De Smaele, Enrico, Modesti, Andrea, Masuelli, Laura

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