Incidence and characteristics of biphasic anaphylaxis: a prospective evaluation of 103 patients von Ellis, Anne K., MD, FRCPC, Day, James H., MD, FRCPC

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Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X‑Linked Inhibitor of Apoptosis Protein (XIAP) von Tamanini, Emiliano, Buck, Ildiko M, Chessari, Gianni, Chiarparin, Elisabetta, Day, James E. H, Frederickson, Martyn, Griffiths-Jones, Charlotte M, Hearn, Keisha, Heightman, Tom D, Iqbal, Aman, Johnson, Christopher N, Lewis, Edward J, Martins, Vanessa, Peakman, Torren, Reader, Michael, Rich, Sharna J, Ward, George A, Williams, Pamela A, Wilsher, Nicola E

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Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP von Chessari, Gianni, Buck, Ildiko M, Day, James E. H, Day, Philip J, Iqbal, Aman, Johnson, Christopher N, Lewis, Edward J, Martins, Vanessa, Miller, Darcey, Reader, Michael, Rees, David C, Rich, Sharna J, Tamanini, Emiliano, Vitorino, Marc, Ward, George A, Williams, Pamela A, Williams, Glyn, Wilsher, Nicola E, Woolford, Alison J.-A

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Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2 von Heightman, Tom D, Berdini, Valerio, Braithwaite, Hannah, Buck, Ildiko M, Cassidy, Megan, Castro, Juan, Courtin, Aurélie, Day, James E. H, East, Charlotte, Fazal, Lynsey, Graham, Brent, Griffiths-Jones, Charlotte M, Lyons, John F, Martins, Vanessa, Muench, Sandra, Munck, Joanne M, Norton, David, O’Reilly, Marc, Palmer, Nick, Pathuri, Puja, Reader, Michael, Rees, David C, Rich, Sharna J, Richardson, Caroline, Saini, Harpreet, Thompson, Neil T, Wallis, Nicola G, Walton, Hugh, Wilsher, Nicola E, Woolford, Alison J.-A, Cooke, Michael, Cousin, David, Onions, Stuart, Shannon, Jonathan, Watts, John, Murray, Christopher W

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Growth vector elaboration of fragments: regioselective functionalization of 5-hydroxy-6-azaindazole and 3-hydroxy-2,6-naphthyridine von Eliandro da Silva Júnior, Paulo, de Melo, Shaiani Maria Gil, de Paula, Murilo Helder, Vessecchi, Ricardo, Opatz, Till, Day, James E. H, Ganesan, A, da Silva Emery, Flavio

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Factors that affect the allergic rhinitis response to ragweed allergen exposure von Ellis, Anne K., MD, MSc, Ratz, Jodan D., PhD, Day, Andrew G., MSc, Day, James H., MD

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Fragment-Based Discovery of Potent and Selective DDR1/2 Inhibitors von Murray, Christopher W, Berdini, Valerio, Buck, Ildiko M, Carr, Maria E, Cleasby, Anne, Coyle, Joseph E, Curry, Jayne E, Day, James E. H, Day, Phillip J, Hearn, Keisha, Iqbal, Aman, Lee, Lydia Y. W, Martins, Vanessa, Mortenson, Paul N, Munck, Joanne M, Page, Lee W, Patel, Sahil, Roomans, Susan, Smith, Kirsten, Tamanini, Emiliano, Saxty, Gordon

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Efficacy of loratadine-montelukast on nasal congestion in patients with seasonal allergic rhinitis in an environmental exposure unit von Day, James H., MD, Briscoe, Maureen P., MD, Ratz, Jodan D., PhD, Danzig, Melvyn, PhD, Yao, Ruji, PhD

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Targeting the Hsp90 Chaperone: Synthesis of Novel Resorcylic Acid Macrolactone Inhibitors of Hsp90 von Day, James E. H., Sharp, Swee Y., Rowlands, Martin G., Aherne, Wynne, Workman, Paul, Moody, Christopher J.

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Diagnosis and management of anaphylaxis von Ellis, Anne K, Day, James H

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Targeting the Hsp90 Molecular Chaperone with Novel Macrolactams. Synthesis, Structural, Binding, and Cellular Studies von Day, James E. H, Sharp, Swee Y, Rowlands, Martin G, Aherne, Wynne, Hayes, Angela, Raynaud, Florence I, Lewis, William, Roe, S. Mark, Prodromou, Chrisostomos, Pearl, Laurence H, Workman, Paul, Moody, Christopher J

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Inhibition of Hsp90 with Resorcylic Acid Macrolactones: Synthesis and Binding Studies von Day, James E. H., Sharp, Swee Y., Rowlands, Martin G., Aherne, Wynne, Lewis, William, Roe, S. Mark, Prodromou, Chrisostomos, Pearl, Laurence H., Workman, Paul, Moody, Christopher J.

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Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase‑2 (SHP2) von Day, James E. H., Berdini, Valerio, Castro, Joan, Chessari, Gianni, Davies, Thomas G., Day, Philip J., St. Denis, Jeffrey D., Fujiwara, Hideto, Fukaya, Satoshi, Hamlett, Christopher C. F., Hearn, Keisha, Hiscock, Steven D., Holvey, Rhian S., Ito, Satoru, Kandola, Navrohit, Kodama, Yasuo, Liebeschuetz, John W., Martins, Vanessa, Matsuo, Kenichi, Mortenson, Paul N., Muench, Sandra, Nakatsuru, Yoko, Ochiiwa, Hiroaki, Palmer, Nicholas, Peakman, Torren, Price, Amanda, Reader, Michael, Rees, David C., Rich, Sharna J., Shah, Alpesh, Shibata, Yoshihiro, Smyth, Tomoko, Twigg, David G., Wallis, Nicola G., Williams, Glyn, Wilsher, Nicola E., Woodhead, Andrew, Shimamura, Tadashi, Johnson, Christopher N.

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A four-way, double-blind, randomized, placebo controlled study to determine the efficacy and speed of azelastine nasal spray, versus loratadine, and cetirizine in adult subjects wi... von Ellis, Anne K, Zhu, Yifei, Steacy, Lisa M, Walker, Terry, Day, James H

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A Fragment-Derived Clinical Candidate for Antagonism of X-Linked and Cellular Inhibitor of Apoptosis Proteins: 1-(6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 H,2 H,... von Johnson, Christopher N, Ahn, Jong Sook, Buck, Ildiko M, Chiarparin, Elisabetta, Day, James E H, Hopkins, Anna, Howard, Steven, Lewis, Edward J, Martins, Vanessa, Millemaggi, Alessia, Munck, Joanne M, Page, Lee W, Peakman, Torren, Reader, Michael, Rich, Sharna J, Saxty, Gordon, Smyth, Tomoko, Thompson, Neil T, Ward, George A, Williams, Pamela A, Wilsher, Nicola E, Chessari, Gianni

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Discovery of ASTX029, A Clinical Candidate Which Modulates the Phosphorylation and Catalytic Activity of ERK1/2 von Heightman, Tom D, Berdini, Valerio, Bevan, Luke, Buck, Ildiko M, Carr, Maria G, Courtin, Aurélie, Coyle, Joseph E, Day, James E H, East, Charlotte, Fazal, Lynsey, Griffiths-Jones, Charlotte M, Howard, Steven, Kucia-Tran, Justyna, Martins, Vanessa, Muench, Sandra, Munck, Joanne M, Norton, David, O'Reilly, Marc, Palmer, Nicholas, Pathuri, Puja, Peakman, Torren M, Reader, Michael, Rees, David C, Rich, Sharna J, Shah, Alpesh, Wallis, Nicola G, Walton, Hugh, Wilsher, Nicola E, Woolford, Alison J-A, Cooke, Michael, Cousin, David, Onions, Stuart, Shannon, Jonathan, Watts, John, Murray, Christopher W

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A comparison of the effect of diphenhydramine and desloratadine on vigilance and cognitive function during treatment of ragweed-induced allergic rhinitis von Wilken, Jeffrey A., Kane, Robert L., Ellis, Anne K., Rafeiro, Elizabeth, Briscoe, Maureen P., Sullivan, Cynthia L., Day, James H.

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The role of epinephrine in the treatment of anaphylaxis von Ellis, Anne K, Day, James H

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Experimental models for the evaluation of treatment of allergic rhinitis von Day, James H., Ellis, Anne K., Rafeiro, Elizabeth, Ratz, Jodan D., Briscoe, Maureen P.

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Clinical reactivity to insect stings von Ellis, Anne K, Day, James H

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