Immunophenotypic correlates of sustained MRD negativity in patients with multiple myeloma von Coffey, David G., Maura, Francesco, Gonzalez-Kozlova, Edgar, Diaz-Mejia, J. Javier, Luo, Ping, Zhang, Yong, Xu, Yuexin, Warren, Edus H., Dawson, Travis, Lee, Brian, Xie, Hui, Smith, Eric, Ciardiello, Amanda, Cho, Hearn J., Rahman, Adeeb, Kim-Schulze, Seunghee, Diamond, Benjamin, Lesokhin, Alexander, Kazandjian, Dickran, Pugh, Trevor J., Green, Damian J., Gnjatic, Sacha, Landgren, Ola

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Modelling Free-Living and Particle-Associated Bacterial Assemblages across the Deep and Hypoxic Lower St. Lawrence Estuary von Cui, Ting Ting, Dawson, Travis J., McLatchie, Susan, Dunn, Katherine, Bielawski, Joseph, Walsh, David A.

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Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma von Magen, Assaf, Hamon, Pauline, Fiaschi, Nathalie, Soong, Brian Y., Park, Matthew D., Mattiuz, Raphaël, Humblin, Etienne, Troncoso, Leanna, D’souza, Darwin, Dawson, Travis, Kim, Joel, Hamel, Steven, Buckup, Mark, Chang, Christie, Tabachnikova, Alexandra, Schwartz, Hara, Malissen, Nausicaa, Lavin, Yonit, Soares-Schanoski, Alessandra, Giotti, Bruno, Hegde, Samarth, Ioannou, Giorgio, Gonzalez-Kozlova, Edgar, Hennequin, Clotilde, Le Berichel, Jessica, Zhao, Zhen, Ward, Stephen C., Fiel, Isabel, Kou, Baijun, Dobosz, Michael, Li, Lianjie, Adler, Christina, Ni, Min, Wei, Yi, Wang, Wei, Atwal, Gurinder S., Kundu, Kunal, Cygan, Kamil J., Tsankov, Alexander M., Rahman, Adeeb, Price, Colles, Fernandez, Nicolas, He, Jiang, Gupta, Namita T., Kim-Schulze, Seunghee, Gnjatic, Sacha, Kenigsberg, Ephraim, Deering, Raquel P., Schwartz, Myron, Marron, Thomas U., Thurston, Gavin, Kamphorst, Alice O., Merad, Miriam

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TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer von Park, Matthew D., Reyes-Torres, Ivan, LeBerichel, Jessica, Hamon, Pauline, LaMarche, Nelson M., Hegde, Samarth, Belabed, Meriem, Troncoso, Leanna, Grout, John A., Magen, Assaf, Humblin, Etienne, Nair, Achuth, Molgora, Martina, Hou, Jinchao, Newman, Jenna H., Farkas, Adam M., Leader, Andrew M., Dawson, Travis, D’Souza, Darwin, Hamel, Steven, Sanchez-Paulete, Alfonso Rodriguez, Maier, Barbara, Bhardwaj, Nina, Martin, Jerome C., Kamphorst, Alice O., Kenigsberg, Ephraim, Casanova-Acebes, Maria, Horowitz, Amir, Brown, Brian D., De Andrade, Lucas Ferrari, Colonna, Marco, Marron, Thomas U., Merad, Miriam

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De Novo Genome and Transcriptome Assembly of the Canadian Beaver ( Castor canadensis ) von Lok, Si, Paton, Tara A, Wang, Zhuozhi, Kaur, Gaganjot, Walker, Susan, Yuen, Ryan K C, Sung, Wilson W L, Whitney, Joseph, Buchanan, Janet A, Trost, Brett, Singh, Naina, Apresto, Beverly, Chen, Nan, Coole, Matthew, Dawson, Travis J, Ho, Karen, Hu, Zhizhou, Pullenayegum, Sanjeev, Samler, Kozue, Shipstone, Arun, Tsoi, Fiona, Wang, Ting, Pereira, Sergio L, Rostami, Pirooz, Ryan, Carol Ann, Tong, Amy Hin Yan, Ng, Karen, Sundaravadanam, Yogi, Simpson, Jared T, Lim, Burton K, Engstrom, Mark D, Dutton, Christopher J, Kerr, Kevin C R, Franke, Maria, Rapley, William, Wintle, Richard F, Scherer, Stephen W

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Establishing a Pathogenic Role for NK Cells As Drivers of Bone Marrow Failure in the Myelodysplastic Syndromes (MDS) von Rai, Richa, Feld, Jonathan, Okulate, Iyinyeloluwa, Melana, Stella, Sheppard, Richard, Demakos, Erin, Hussein, Shafinaz, Chen, Rachel, Lee, Rachel, de Real, Ronaldo, Kelly, Geoffrey, Lee, Brian, Dawson, Travis, Chen, Zhihong, Roudko, Vladimir, kim-Schulze, Seunghee, Silverman, Lewis R R., Horowitz, Amir

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Dysregulation of Cellular Immunity in High-Risk Multiple Myeloma von Bekri, Selma, Katz, Simone, Kelly, Geoffrey, Dawson, Travis, D'Souza, Darwin, Mason, Michael, Alloy, Alexandre, Biswas, Shameek, Kim-Schulze, Seunghee, Gnjatic, Sacha, Parekh, Samir, Jagannath, Sundar, Lagana, Alessandro, Cho, Hearn Jay

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Limited extent and consequences of pancreatic SARS-CoV-2 infection von van der Heide, Verena, Jangra, Sonia, Cohen, Phillip, Rathnasinghe, Raveen, Aslam, Sadaf, Aydillo, Teresa, Geanon, Daniel, Handler, Diana, Kelley, Geoffrey, Lee, Brian, Rahman, Adeeb, Dawson, Travis, Qi, Jingjing, D'Souza, Darwin, Kim-Schulze, Seunghee, Panzer, Julia K., Caicedo, Alejandro, Kusmartseva, Irina, Posgai, Amanda L., Atkinson, Mark A., Albrecht, Randy A., García-Sastre, Adolfo, Rosenberg, Brad R., Schotsaert, Michael, Homann, Dirk

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Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae von Thompson, Ryan C., Simons, Nicole W., Wilkins, Lillian, Cheng, Esther, Del Valle, Diane Marie, Hoffman, Gabriel E., Cervia, Carlo, Fennessy, Brian, Mouskas, Konstantinos, Francoeur, Nancy J., Johnson, Jessica S., Lepow, Lauren, Le Berichel, Jessica, Chang, Christie, Beckmann, Aviva G., Wang, Ying-chih, Nie, Kai, Zaki, Nicholas, Tuballes, Kevin, Barcessat, Vanessa, Cedillo, Mario A., Yuan, Dan, Huckins, Laura, Roussos, Panos, Marron, Thomas U., Glicksberg, Benjamin S., Nadkarni, Girish, Heath, James R., Gonzalez-Kozlova, Edgar, Boyman, Onur, Kim-Schulze, Seunghee, Sebra, Robert, Merad, Miriam, Gnjatic, Sacha, Schadt, Eric E., Charney, Alexander W., Beckmann, Noam D.

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Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children von Beckmann, Noam D., Comella, Phillip H., Cheng, Esther, Lepow, Lauren, Beckmann, Aviva G., Tyler, Scott R., Mouskas, Konstantinos, Simons, Nicole W., Hoffman, Gabriel E., Francoeur, Nancy J., Del Valle, Diane Marie, Kang, Gurpawan, Do, Anh, Moya, Emily, Wilkins, Lillian, Le Berichel, Jessica, Chang, Christie, Marvin, Robert, Calorossi, Sharlene, Lansky, Alona, Walker, Laura, Yi, Nancy, Yu, Alex, Chung, Jonathan, Hartnett, Matthew, Eaton, Melody, Hatem, Sandra, Jamal, Hajra, Akyatan, Alara, Tabachnikova, Alexandra, Liharska, Lora E., Cotter, Liam, Fennessy, Brian, Vaid, Akhil, Barturen, Guillermo, Shah, Hardik, Wang, Ying-chih, Sridhar, Shwetha Hara, Soto, Juan, Bose, Swaroop, Madrid, Kent, Ellis, Ethan, Merzier, Elyze, Vlachos, Konstantinos, Fishman, Nataly, Tin, Manying, Smith, Melissa, Xie, Hui, Patel, Manishkumar, Nie, Kai, Argueta, Kimberly, Harris, Jocelyn, Karekar, Neha, Batchelor, Craig, Lacunza, Jose, Yishak, Mahlet, Tuballes, Kevin, Scott, Ieisha, Kumar, Arvind, Jaladanki, Suraj, Agashe, Charuta, Thompson, Ryan, Clark, Evan, Losic, Bojan, Peters, Lauren, Roussos, Panagiotis, Zhu, Jun, Wang, Wenhui, Kasarskis, Andrew, Glicksberg, Benjamin S., Nadkarni, Girish, Bogunovic, Dusan, Elaiho, Cordelia, Gangadharan, Sandeep, Ofori-Amanfo, George, Alesso-Carra, Kasey, Onel, Kenan, Wilson, Karen M., Argmann, Carmen, Bunyavanich, Supinda, Alarcón-Riquelme, Marta E., Marron, Thomas U., Rahman, Adeeb, Kim-Schulze, Seunghee, Gnjatic, Sacha, Gelb, Bruce D., Merad, Miriam, Sebra, Robert, Schadt, Eric E., Charney, Alexander W.

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In-Depth Characterization of the High Risk-Associated Tumor Immune Landscape in Multiple Myeloma von Pita-Juarez, Yered, Karagkouni, Dimitra, Gonzalez-Kozlova, Edgar, Ma, Yuling, Yao, Lijun, Pilcher, William, Thomas, Beena, Lagana, Alessandro, Satpathy, Sarthak, Bhasin, Swati, Song, Yizhe, Vij, Ravi, D'Souza, Darwin, Dawson, Travis, Kelly, Geoffrey, Schulman, Jessica Wendy, Kumar, Shaji Kunnathu, Avigan, David, Kim-Schulze, Seunghee, Ding, Li, Cho, Hearn Jay, Kourelis, Taxiarchis, Lepisto, Eva, Bhasin, Manoj, Cook, April, Hamilton, Mark, Mulligan, George, Network, Immune, Vlachos, Ioannis, Gnjatic, Sacha

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Hematopoietic aging promotes cancer by fueling IL-1α-driven emergency myelopoiesis von Park, Matthew D., Berichel, Jessica Le, Hamon, Pauline, Wilk, C. Matthias, Belabed, Meriem, Yatim, Nader, Saffon, Alexis, Boumelha, Jesse, Falcomatà, Chiara, Tepper, Alexander, Hegde, Samarth, Mattiuz, Raphaël, Soong, Brian Y., LaMarche, Nelson M., Rentzeperis, Frederika, Troncoso, Leanna, Halasz, Laszlo, Hennequin, Clotilde, Chin, Theodore, Chen, Earnest P., Reid, Amanda M., Su, Matthew, Cahn, Ashley Reid, Koekkoek, Laura L., Venturini, Nicholas, Wood-isenberg, Shira, D’souza, Darwin, Chen, Rachel, Dawson, Travis, Nie, Kai, Chen, Zhihong, Kim-Schulze, Seunghee, Casanova-Acebes, Maria, Swirski, Filip K., Downward, Julian, Vabret, Nicolas, Brown, Brian D., Marron, Thomas U., Merad, Miriam

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P-198 Immunomodulatory Effects of Daratumumab on the Bone Marrow Microenvironment in Multiple Myeloma: Insights from Single-Cell Analyses von Bekri, Selma, Damle, Gargi, Demircioglu, Deniz, Kats, Simone, Kelly, Geoffrey, Dawson, Travis, Darwin, D'souza, Collins, Sabrina, Kim-Schulze, Seunghee, Gnjatic, Sacha, Parekh, Samir, Jagannath, Sundar, Lagana, Alessandro, Cho, Hearn Jay

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OA-23 Differential Immunophenotypic and Genetic Landscapes of High-Risk and Standard-Risk Multiple Myeloma Patients von Bekri, Selma, Damle, Gargi, Demircioglu, Deniz, Kats, Simone, Coffey, David G, Kelly, Geoffrey, Dawson, Travis, Darwin, D'souza, Mason, Mike, Alloy, Alexandre P, Biswas, Shameek, Kim-Schulze, Seunghee, Gnjatic, Sacha, Parekh, Samir, Jagannath, Sundar, Lagana, Alessandro, Cho, Hearn Jay

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571 VEDOLIZUMAB RESPONSE IN ULCERATIVE COLITIS ASSOCIATES WITH LYMPHOID AGGREGATE ATTENUATION THROUGH IMPAIRED RECRUITMENT OF NAÏVE LYMPHOCYTES von Canales-Herrerias, Pablo, Uzzan, Mathieu, Seki, Akihiro, Czepielewski, Rafael S., Verstockt, Bram, Dunn, Alexandra, Dai, Daniel S., Ko, Huaibin M., Furtado, Glaucia C., Tokuyama, Minami, Tankelevich, Michael, Meringer, Hadar, Cossarini, Francesca, Jha, Divya, Paulsen, John D., Nakadar, Mohammad Zuber, Wong, Joshua, Sharma, Keshav, Rosenstein, Adam, Dawson, Travis, Singh, Harpriya, Lim, Jean, Lira, Sergio A., Yajnik, Vijay, Reboldi, Andrea, Petralia, Francesca, Vermeire, Severine, Polydorides, Alexandros D., Randolph, Gwendalyn J., Colombel, Jean Frederic, Mehandru, Saurabh

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Myocardial infarction augments sleep to limit cardiac inflammation and damage von Huynh, Pacific, Hoffmann, Jan D., Gerhardt, Teresa, Kiss, Máté G., Zuraikat, Faris M., Cohen, Oren, Wolfram, Christopher, Yates, Abi G., Leunig, Alexander, Heiser, Merlin, Gaebel, Lena, Gianeselli, Matteo, Goswami, Sukanya, Khamhoung, Annie, Downey, Jeffrey, Yoon, Seonghun, Chen, Zhihong, Roudko, Vladimir, Dawson, Travis, Ferreira da Silva, Joana, Ameral, Natalie J., Morgenroth-Rebin, Jarod, D’Souza, Darwin, Koekkoek, Laura L., Jacob, Walter, Munitz, Jazz, Lee, Donghoon, Fullard, John F., van Leent, Mandy M. T., Roussos, Panos, Kim-Schulze, Seunghee, Shah, Neomi, Kleinstiver, Benjamin P., Swirski, Filip K., Leistner, David, St-Onge, Marie-Pierre, McAlpine, Cameron S.

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Hematopoietic aging promotes cancer by fueling IL-1⍺-driven emergency myelopoiesis von Park, Matthew D, Le Berichel, Jessica, Hamon, Pauline, Wilk, C Matthias, Belabed, Meriem, Yatim, Nader, Saffon, Alexis, Boumelha, Jesse, Falcomatà, Chiara, Tepper, Alexander, Hegde, Samarth, Mattiuz, Raphaël, Soong, Brian Y, LaMarche, Nelson M, Rentzeperis, Frederika, Troncoso, Leanna, Halasz, Laszlo, Hennequin, Clotilde, Chin, Theodore, Chen, Earnest P, Reid, Amanda M, Su, Matthew, Cahn, Ashley Reid, Koekkoek, Laura L, Venturini, Nicholas, Wood-Isenberg, Shira, D'souza, Darwin, Chen, Rachel, Dawson, Travis, Nie, Kai, Chen, Zhihong, Kim-Schulze, Seunghee, Casanova-Acebes, Maria, Swirski, Filip K, Downward, Julian, Vabret, Nicolas, Brown, Brian D, Marron, Thomas U, Merad, Miriam

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Single-Cell RNA-Seq Analysis of CD138-Depleted Bone Marrow Samples Reveals Genetic Alterations and Disease Progression Correlate with Tumor and Bone Marrow Immune Microenvironment... von Yao, Lijun, Wang, Tianjiao, Kazuhiro, Sato, Jayasinghe, Reyka G, Pilcher, William, Gonzalez-Kozlova, Edgar, Pita-Juarez, Yered, Kourelis, Taxiarchis, Doxie, Deon, Thomas, Beena E, Lee, Brian, Bhasin, Swati S, Upadhyaya, Bhaskar, Fiala, Mark A, Fortier, Julie, Dawson, Travis, Leech, John, Kumar, Shaji, Cho, Hearn Jay, Kim-Schulze, Seunghee, Raj, Bee, Oh, Stephen T., DiPersio, John F., Vij, Ravi, Rahman, Adeeb H, Vlachos, Ioannis, Mehr, Shaadi, Hamilton, Mark, Auclair, Daniel, Dasari, Surendra, Avigan, David, Dhodapkar, Madhav V, Gnjatic, Sacha, Bhasin, Manoj, Ding, Li

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P-404 Single-cell profiling reveals inflammaging-associated dysregulations in rapidly progressing multiple myeloma patients von Pilcher, William, Yao, Lijun, Kozlova, Edgar Gonzalez, Pita-Juarez, Yered, Karagkouni, Dimitra, Ma, Yuling, Thomas, Beena, Satpathy, Sarthak, Bhasin, Swati, Song, Yizhe, Wang, Julia, Dawson, Travis, D'souza, Darwin, Network, Immune, Schulman, Jessica, Pabustan, Nick, Cook, April, Cho, Hearn Jay, Mulligan, George, Hamilton, Mark, Kourelis, Taxiarchis, Vlachos, Ioannis, Gnjatic, Sacha, Ding, Li, Bhasin, Manoj

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Sampling the host response to SARS-CoV-2 in hospitals under siege (vol 26, pg 1157, 2020) von Charney, Alexander W., Simons, Nicole W., Mouskas, Konstantinos, Lepow, Lauren, Cheng, Esther, Le Berichel, Jessica, Chang, Christie, Marvin, Robert, Del Valle, Diane Marie, Calorossi, Sharlene, Lansky, Alona, Walker, Laura, Patel, Manishkumar, Xie, Hui, Yi, Nancy, Yu, Alex, Kang, Gurpawan, Liharska, Lora E., Moya, Emily, Hartnett, Matthew, Hatem, Sandra, Wilkins, Lillian, Eaton, Melody, Jamal, Hajra, Tuballes, Kevin, Chen, Steven T., Tabachnikova, Alexandra, Chung, Jonathan, Harris, Jocelyn, Batchelor, Craig, Lacunza, Jose, Yishak, Mahlet, Argueta, Kimberly, Karekar, Neha, Lee, Brian, Kelly, Geoffrey, Geanon, Daniel, Handler, Diana, Leech, John, Stefanos, Hiyab, Dawson, Travis, Scott, Ieisha, Francoeur, Nancy, Johnson, Jessica S., Vaid, Akhil, Glicksberg, Benjamin S., Nadkarni, Girish N., Schadt, Eric E., Gelb, Bruce D., Rahman, Adeeb, Sebra, Robert, Martin, Glenn, Agashe, Charuta, Agashe, Charuta, Agrawal, Priyal, Alesso-Carra, Kasey, Alibo, Eziwoma, Alvarez, Kelvin, Amabile, Angelo, Ascolillo, Steven, Bailey, Rasheed, Begani, Priya, Correra, Paloma Bravo, Brown, Stacey-Ann, Buckup, Mark, Burka, Larissa, Cambron, Lena, Carrara, Gina, Chang, Serena, Chien, Jonathan, Chowdhury, Mashkura, Bozkus, Cansu Cimen, Comella, Phillip, Cosgrove, Dana, Cossarini, Francesca, Cotter, Liam, Dave, Arpit, Dayal, Bheesham, Dhainaut, Maxime, Dornfeld, Rebecca, Dul, Katie, Eber, Nissan, Elaiho, Cordelia, Fabris, Frank, Faith, Jeremiah, Falci, Dominique, Feng, Susie, Fennessy, Brian, Fernandes, Marie, Gangadharan, Sandeep, Grabowska, Joanna, Gyimesi, Gavin, Hamdani, Maha, Herbinet, Manon, Herrera, Elva, Hochman, Arielle, Hoffman, Gabriel E., Hook, Jaime, Horta, Laila, Humblin, Etienne

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