The cancer epigenome: Concepts, challenges, and therapeutic opportunities von Dawson, Mark A.

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Cancer Epigenetics: From Mechanism to Therapy von Dawson, Mark A., Kouzarides, Tony

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Non-genetic mechanisms of therapeutic resistance in cancer von Marine, Jean-Christophe, Dawson, Sarah-Jane, Dawson, Mark A.

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Targeting the epigenetic regulation of antitumour immunity von Hogg, Simon J., Beavis, Paul A., Dawson, Mark A., Johnstone, Ricky W.

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Ibrutinib plus Venetoclax for the Treatment of Mantle-Cell Lymphoma von Tam, Constantine S, Anderson, Mary Ann, Pott, Christiane, Agarwal, Rishu, Handunnetti, Sasanka, Hicks, Rodney J, Burbury, Kate, Turner, Gillian, Di Iulio, Juliana, Bressel, Mathias, Westerman, David, Lade, Stephen, Dreyling, Martin, Dawson, Sarah-Jane, Dawson, Mark A, Seymour, John F, Roberts, Andrew W

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An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer von Burr, Marian L., Sparbier, Christina E., Chan, Kah Lok, Chan, Yih-Chih, Kersbergen, Ariena, Lam, Enid Y.N., Azidis-Yates, Elizabeth, Vassiliadis, Dane, Bell, Charles C., Gilan, Omer, Jackson, Susan, Tan, Lavinia, Wong, Stephen Q., Hollizeck, Sebastian, Michalak, Ewa M., Siddle, Hannah V., McCabe, Michael T., Prinjha, Rab K., Guerra, Glen R., Solomon, Benjamin J., Sandhu, Shahneen, Dawson, Sarah-Jane, Beavis, Paul A., Tothill, Richard W., Cullinane, Carleen, Lehner, Paul J., Sutherland, Kate D., Dawson, Mark A.

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Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation von Gilan, Omer, Rioja, Inmaculada, Knezevic, Kathy, Bell, Matthew J, Yeung, Miriam M, Harker, Nicola R, Lam, Enid Y N, Chung, Chun-Wa, Bamborough, Paul, Petretich, Massimo, Urh, Marjeta, Atkinson, Stephen J, Bassil, Anna K, Roberts, Emma J, Vassiliadis, Dane, Burr, Marian L, Preston, Alex G S, Wellaway, Christopher, Werner, Thilo, Gray, James R, Michon, Anne-Marie, Gobbetti, Thomas, Kumar, Vinod, Soden, Peter E, Haynes, Andrea, Vappiani, Johanna, Tough, David F, Taylor, Simon, Dawson, Sarah-Jane, Bantscheff, Marcus, Lindon, Matthew, Drewes, Gerard, Demont, Emmanuel H, Daniels, Danette L, Grandi, Paola, Prinjha, Rab K, Dawson, Mark A

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Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia von Deniz, Özgen, Ahmed, Mamataz, Todd, Christopher D., Rio-Machin, Ana, Dawson, Mark A., Branco, Miguel R.

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Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells von Tchasovnikarova, Iva A., Timms, Richard T., Matheson, Nicholas J., Wals, Kim, Antrobus, Robin, Göttgens, Berthold, Dougan, Gordon, Dawson, Mark A., Lehner, Paul J.

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Non-genetic determinants of malignant clonal fitness at single-cell resolution von Fennell, Katie A., Vassiliadis, Dane, Lam, Enid Y. N., Martelotto, Luciano G., Balic, Jesse J., Hollizeck, Sebastian, Weber, Tom S., Semple, Timothy, Wang, Qing, Miles, Denise C., MacPherson, Laura, Chan, Yih-Chih, Guirguis, Andrew A., Kats, Lev M., Wong, Emily S., Dawson, Sarah-Jane, Naik, Shalin H., Dawson, Mark A.

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Detection of cell-free microbial DNA using a contaminant-controlled analysis framework von Zozaya-Valdés, Enrique, Wong, Stephen Q, Raleigh, Jeanette, Hatzimihalis, Athena, Ftouni, Sarah, Papenfuss, Anthony T, Sandhu, Shahneen, Dawson, Mark A, Dawson, Sarah-Jane

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Click chemistry enables preclinical evaluation of targeted epigenetic therapies von Tyler, Dean S., Vappiani, Johanna, Cañeque, Tatiana, Lam, Enid Y. N., Ward, Aoife, Gilan, Omer, Chan, Yih-Chih, Hienzsch, Antje, Rutkowska, Anna, Werner, Thilo, Wagner, Anne J., Lugo, Dave, Gregory, Richard, Molina, Cesar Ramirez, Garton, Neil, Wellaway, Christopher R., Jackson, Susan, MacPherson, Laura, Figueiredo, Margarida, Stolzenburg, Sabine, Bell, Charles C., House, Colin, Dawson, Sarah-Jane, Hawkins, Edwin D., Drewes, Gerard, Prinjha, Rab K., Rodriguez, Raphaël, Grandi, Paola, Dawson, Mark A.

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TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS von Deplus, Rachel, Delatte, Benjamin, Schwinn, Marie K, Defrance, Matthieu, Méndez, Jacqui, Murphy, Nancy, Dawson, Mark A, Volkmar, Michael, Putmans, Pascale, Calonne, Emilie, Shih, Alan H, Levine, Ross L, Bernard, Olivier, Mercher, Thomas, Solary, Eric, Urh, Marjeta, Daniels, Danette L, Fuks, François

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Epigenetics in the hematologic malignancies von Fong, Chun Yew, Morison, Jessica, Dawson, Mark A

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From little things big things grow von Dawson, Mark A

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Circulating tumour DNA reflects treatment response and clonal evolution in chronic lymphocytic leukaemia von Yeh, Paul, Hunter, Tane, Sinha, Devbarna, Ftouni, Sarah, Wallach, Elise, Jiang, Damian, Chan, Yih-Chih, Wong, Stephen Q., Silva, Maria Joao, Vedururu, Ravikiran, Doig, Kenneth, Lam, Enid, Arnau, Gisela Mir, Semple, Timothy, Wall, Meaghan, Zivanovic, Andjelija, Agarwal, Rishu, Petrone, Pasquale, Jones, Kate, Westerman, David, Blombery, Piers, Seymour, John F., Papenfuss, Anthony T., Dawson, Mark A., Tam, Constantine S., Dawson, Sarah-Jane

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Circulating tumour DNA in metastatic breast cancer to guide clinical trial enrolment and precision oncology: A cohort study von Zivanovic Bujak, Andjelija, Weng, Chen-Fang, Silva, Maria João, Yeung, Miriam, Lo, Louisa, Ftouni, Sarah, Litchfield, Cassandra, Ko, Yi-An, Kuykhoven, Keilly, Van Geelen, Courtney, Chandrashekar, Sushma, Dawson, Mark A, Loi, Sherene, Wong, Stephen Q, Dawson, Sarah-Jane

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Molecular disease monitoring using circulating tumor DNA in myelodysplastic syndromes von Yeh, Paul, Dickinson, Michael, Ftouni, Sarah, Hunter, Tane, Sinha, Devbarna, Wong, Stephen Q., Agarwal, Rishu, Vedururu, Ravikiran, Doig, Kenneth, Fong, Chun Yew, Blombery, Piers, Westerman, David, Dawson, Mark A., Dawson, Sarah-Jane

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A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells von Guo, Lei, Li, Jia, Zeng, Hongxiang, Guzman, Anna G., Li, Tingting, Lee, Minjung, Zhou, Yubin, Goodell, Margaret A., Stephan, Clifford, Davies, Peter J. A., Dawson, Mark A, Sun, Deqiang, Huang, Yun

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Heterochromatin protein 1 alpha (HP1α) undergoes a monomer to dimer transition that opens and compacts live cell genome architecture von Lou, Jieqiong, Deng, Qiji, Zhang, Xiaomeng, Bell, Charles C, Das, Andrew B, Bediaga, Naiara G, Zlatic, Courtney O, Johanson, Timothy M, Allan, Rhys S, Griffin, Michael D W, Paradkar, PrasadN, Harvey, Kieran F, Dawson, Mark A, Hinde, Elizabeth

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