Effects of RG7652, a Monoclonal Antibody Against PCSK9, on LDL-C, LDL-C Subfractions, and Inflammatory Biomarkers in Patients at High Risk of or With Established Coronary Heart Dis... von Baruch, Amos, PhD, Mosesova, Sofia, PhD, Davis, John D., PhD, Budha, Nageshwar, PhD, Vilimovskij, Alexandr, MD, Kahn, Robert, MD, Peng, Kun, PhD, Cowan, Kyra J., PhD, Harris, Laura Pascasio, MPH, Gelzleichter, Thomas, PhD, Lehrer, Josh, MD, Davis, John C., MD, Tingley, Whittemore G., MD

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Pharmacokinetics and pharmacodynamics of itepekimab in healthy adults and patients with asthma: Phase I first‐in‐human and first‐in‐patient trials von Kosloski, Matthew P., Kalliolias, George D., Xu, Christine R., Harel, Sivan, Lai, Ching‐Ha, Zheng, Wenjun, Davis, John D., Kamal, Mohamed A.

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Dupilumab: Mechanism of action, clinical, and translational science von McCann, Marc R., Kosloski, Matthew P., Xu, Christine, Davis, John D., Kamal, Mohamed A.

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Projecting human pharmacokinetics of monoclonal antibodies from nonclinical data: comparative evaluation of prediction approaches in early drug development von Wang, Jing, Iyer, Suhasini, Fielder, Paul J., Davis, John D., Deng, Rong

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Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Dupilumab in Healthy Adult Subjects von Li, Zhaoyang, Radin, Allen, Li, Meng, Hamilton, Jennifer D., Kajiwara, Miyuki, Davis, John D., Takahashi, Yoshinori, Hasegawa, Setsuo, Ming, Jeffrey E., DiCioccio, A. Thomas, Li, Yongtao, Kovalenko, Pavel, Lu, Qiang, Ortemann‐Renon, Catherine, Ardeleanu, Marius, Swanson, Brian N.

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Pharmacokinetics and pharmacodynamics of mibavademab (a leptin receptor agonist): Results from a first‐in‐human phase I study von Gewitz, Andrew, Mendell, Jeanne, Wang, Yuhuan, Harris, Charles, Olenchock, Benjamin A., Podgrabinska, Simona, Zheng, Wenjun, Zhao, An, Pan, Hao, Vanhoutte, Frédéric, Davis, John D.

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Assessing the safety and pharmacokinetics of casirivimab and imdevimab (CAS+IMD) in a cohort of pregnant outpatients with COVID-19: results from an adaptive, multicentre, randomise... von Norton, Thomas D, Thakur, Mazhar, Ganguly, Samit, Ali, Shazia, Chao, Jesse, Waldron, Alpana, Xiao, Jing, Patel, Yogesh, Turner, Kenneth C, Davis, John D, Irvin, Susan C, Pan, Cynthia, Atmodjo-Watkins, Dominique, Hooper, Andrea T, Hamilton, Jennifer D, Subramaniam, Danise, Bocchini, Joseph A, Kowal, Bari, DiCioccio, A. Thomas, Bhore, Rafia, Geba, Gregory P, Cox, Edward, Braunstein, Ned, Dakin, Paula, Herman, Gary A

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Immunogenicity of dupilumab in adult and pediatric patients with atopic dermatitis von Kamal, Mohamed A, Kosloski, Matthew P, Lai, Ching-Ha, Partridge, Michael A, Rajadhyaksha, Manoj, Kanamaluru, Vanaja, Bansal, Ashish, Shabbir, Arsalan, Shumel, Brad, Ardeleanu, Marius, Richards, Susan M, Yan, Hong, Xu, Christine R, Rodríguez-Marco, Ainara, Xiao, Jing, Khokhar, Faisal A, Gherardi, Guy, Babilonia, Elisa, Maloney, Jennifer, Mortensen, Eric, Akinlade, Bolanle, Braunstein, Ned, Stahl, Neil, Torri, Albert, Davis, John D, DiCioccio, A Thomas

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REGN1908‐1909 monoclonal antibodies block Fel d 1 in cat allergic subjects: Translational pharmacokinetics and pharmacodynamics von Kamal, Mohamed A., Dingman, Robert, Wang, Claire Q., Lai, Ching‐Ha, Rajadhyaksha, Manoj, DeVeaux, Michelle, Orengo, Jamie M., Radin, Allen, Davis, John D.

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Population pharmacokinetic analysis of dupilumab in adult and adolescent patients with asthma von Zhang, Li, Gao, Yue, Li, Meng, Xu, Christine, Davis, John D., Kanamaluru, Vanaja, Lu, Qiang

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REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19 von Weinreich, David M, Sivapalasingam, Sumathi, Norton, Thomas, Ali, Shazia, Gao, Haitao, Bhore, Rafia, Musser, Bret J, Soo, Yuhwen, Rofail, Diana, Im, Joseph, Perry, Christina, Pan, Cynthia, Hosain, Romana, Mahmood, Adnan, Davis, John D, Turner, Kenneth C, Hooper, Andrea T, Hamilton, Jennifer D, Baum, Alina, Kyratsous, Christos A, Kim, Yunji, Cook, Amanda, Kampman, Wendy, Kohli, Anita, Sachdeva, Yessica, Graber, Ximena, Kowal, Bari, DiCioccio, Thomas, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary, Yancopoulos, George D

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Population pharmacokinetics and exposure–response modeling for evinacumab in homozygous familial hypercholesterolemia von Pu, Xia, Sale, Mark, Yang, Feng, Zhang, Yi, Davis, John D., Al‐Huniti, Nidal

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Pharmacokinetics and pharmacodynamics of itepekimab in adults with moderate‐to‐severe atopic dermatitis: Results from two terminated phase II trials von Kosloski, Matthew P., Guttman‐Yassky, Emma, Cork, Michael J., Worm, Margitta, Nahm, Dong‐Ho, Zhu, Xiaoping, Ruddy, Marcella K., Harel, Sivan, Kamal, Mohamed A., Goulaouic, Hélène, Xu, Christine R., Avetisova, Elena, Davis, John D., Nivens, Michael C., Shabbir, Arsalan, Radin, Allen

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REGEN-COV Antibody Combination and Outcomes in Outpatients with Covid-19 von Weinreich, David M, Sivapalasingam, Sumathi, Norton, Thomas, Ali, Shazia, Gao, Haitao, Bhore, Rafia, Xiao, Jing, Hooper, Andrea T, Hamilton, Jennifer D, Musser, Bret J, Rofail, Diana, Hussein, Mohamed, Im, Joseph, Atmodjo, Dominique Y, Perry, Christina, Pan, Cynthia, Mahmood, Adnan, Hosain, Romana, Davis, John D, Turner, Kenneth C, Baum, Alina, Kyratsous, Christos A, Kim, Yunji, Cook, Amanda, Kampman, Wendy, Roque-Guerrero, Lilia, Acloque, Gerard, Aazami, Hessam, Cannon, Kevin, Simón-Campos, J. Abraham, Bocchini, Joseph A, Kowal, Bari, DiCioccio, A. Thomas, Soo, Yuhwen, Geba, Gregory P, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary, Yancopoulos, George D

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Pharmacokinetics, pharmacodynamics, and exposure–efficacy of dupilumab in adults with atopic dermatitis von Kamal, Mohamed A., Davis, John D., Kovalenko, Pavel, Srinivasan, Kamal, Simpson, Eric L., Nakahara, Takeshi, Sugaya, Makoto, Igarashi, Atsuyuki, Ardeleanu, Marius, Xu, Christine, Arima, Kazuhiko

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Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19 von O’Brien, Meagan P, Forleo-Neto, Eduardo, Musser, Bret J, Isa, Flonza, Chan, Kuo-Chen, Sarkar, Neena, Bar, Katharine J, Barnabas, Ruanne V, Barouch, Dan H, Cohen, Myron S, Hurt, Christopher B, Burwen, Dale R, Marovich, Mary A, Hou, Peijie, Heirman, Ingeborg, Davis, John D, Turner, Kenneth C, Ramesh, Divya, Mahmood, Adnan, Hooper, Andrea T, Hamilton, Jennifer D, Kim, Yunji, Purcell, Lisa A, Baum, Alina, Kyratsous, Christos A, Krainson, James, Perez-Perez, Richard, Mohseni, Rizwana, Kowal, Bari, DiCioccio, A. Thomas, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary, Yancopoulos, George D, Weinreich, David M

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Efficacy and safety of dupilumab with concomitant topical corticosteroids in children 6 to 11 years old with severe atopic dermatitis: A randomized, double-blinded, placebo-control... von Paller, Amy S., Siegfried, Elaine C., Thaçi, Diamant, Wollenberg, Andreas, Cork, Michael J., Arkwright, Peter D., Gooderham, Melinda, Beck, Lisa A., Boguniewicz, Mark, Sher, Lawrence, Weisman, Jamie, O'Malley, John T., Patel, Naimish, Hardin, Megan, Graham, Neil M.H., Ruddy, Marcella, Sun, Xian, Davis, John D., Kamal, Mohamed A., Khokhar, Faisal A., Weinreich, David M., Yancopoulos, George D., Beazley, Bethany, Bansal, Ashish, Shumel, Brad

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Population pharmacokinetics modeling and exposure‐response analyses of cemiplimab in patients with recurrent or metastatic cervical cancer von Nguyen, Jenny‐Hoa, Epling, Daniel, Dolphin, Nancy, Paccaly, Anne, Conrado, Daniela, Davis, John D., Al‐Huniti, Nidal

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Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis: A Phase 3 Randomized Clinical Trial von Simpson, Eric L, Paller, Amy S, Siegfried, Elaine C, Boguniewicz, Mark, Sher, Lawrence, Gooderham, Melinda J, Beck, Lisa A, Guttman-Yassky, Emma, Pariser, David, Blauvelt, Andrew, Weisman, Jamie, Lockshin, Benjamin, Hultsch, Thomas, Zhang, Qin, Kamal, Mohamed A, Davis, John D, Akinlade, Bolanle, Staudinger, Heribert, Hamilton, Jennifer D, Graham, Neil M. H, Pirozzi, Gianluca, Gadkari, Abhijit, Eckert, Laurent, Stahl, Neil, Yancopoulos, George D, Ruddy, Marcella, Bansal, Ashish

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A drug‐disease model for predicting survival in an Ebola outbreak von Toroghi, Masood Khaksar, Al‐Huniti, Nidal, Davis, John D., DiCioccio, A. Thomas, Rippley, Ronda, Baum, Alina, Kyratsous, Christos A., Sivapalasingam, Sumathi, Kantrowitz, Joel, Kamal, Mohamed A.

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