PP25. DISTRIBUTION OF IDH1 AND TERT MUTATIONS AND MGMT METHYLATION IN ADULT LOWER GRADE GLIOMA von Singh, Dr Anushree, Karakoula, Dr Katherine, Ashton, Mrs Kate, Dawson, Prof Tim, Davis, Prof Charles, Brodbelt, Mr Andrew, Jenkinson, Mr Michael, Darling, Prof John, Warr, Prof Tracy

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Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial von Gauthier, Serge, Prof, Feldman, Howard H, Prof, Schneider, Lon S, Prof, Wilcock, Gordon K, Prof, Frisoni, Giovanni B, Prof, Hardlund, Jiri H, MD, Moebius, Hans J, MD, Bentham, Peter, MBChB, Kook, Karin A, PhD, Wischik, Damon J, PhD, Schelter, Bjoern O, Prof, Davis, Charles S, PhD, Staff, Roger T, PhD, Bracoud, Luc, MSc, Shamsi, Kohkan, MD, Storey, John M D, Prof, Harrington, Charles R, PhD, Wischik, Claude M, Prof

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Definition and classification of cancer cachexia: an international consensus von Fearon, Kenneth, Prof, Strasser, Florian, Prof, Anker, Stefan D, Prof, Bosaeus, Ingvar, Prof, Bruera, Eduardo, Prof, Fainsinger, Robin L, Prof, Jatoi, Aminah, Prof, Loprinzi, Charles, Prof, MacDonald, Neil, Prof, Mantovani, Giovanni, Prof, Davis, Mellar, Prof, Muscaritoli, Maurizio, Prof, Ottery, Faith, MD, Radbruch, Lukas, Prof, Ravasco, Paula, MD, Walsh, Declan, Prof, Wilcock, Andrew, MD, Kaasa, Stein, Prof, Baracos, Vickie E, Prof

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Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials von Goyal, Mayank, Prof, Menon, Bijoy K, MD, van Zwam, Wim H, MD, Dippel, Diederik W J, Prof, Mitchell, Peter J, Prof, Demchuk, Andrew M, Prof, Dávalos, Antoni, Prof, Majoie, Charles B L M, Prof, van der Lugt, Aad, Prof, de Miquel, Maria A, MD, Donnan, Geoffrey A, Prof, Roos, Yvo B W E M, Prof, Bonafe, Alain, Prof, Jahan, Reza, MD, Diener, Hans-Christoph, Prof, van den Berg, Lucie A, MD, Levy, Elad I, Prof, Berkhemer, Olvert A, MD, Pereira, Vitor M, MD, Rempel, Jeremy, MD, Millán, Mònica, MD, Davis, Stephen M, Prof, Roy, Daniel, Prof, Thornton, John, MD, Román, Luis San, MD, Ribó, Marc, MD, Beumer, Debbie, MD, Stouch, Bruce, Prof, Brown, Scott, PhD, Campbell, Bruce C V, MD, van Oostenbrugge, Robert J, Prof, Saver, Jeffrey L, Prof, Hill, Michael D, Prof, Jovin, Tudor G, Dr

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Myostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial von Becker, Clemens, Prof, Lord, Stephen R, Prof, Studenski, Stephanie A, MD, Warden, Stuart J, PhD, Fielding, Roger A, Prof, Recknor, Christopher P, MD, Hochberg, Marc C, Prof, Ferrari, Serge L, Prof, Blain, Hubert, Prof, Binder, Ellen F, Prof, Rolland, Yves, Prof, Poiraudeau, Serge, Prof, Benson, Charles T, MD, Myers, Stephen L, MD, Hu, Leijun, PhD, Ahmad, Qasim I, MD, Pacuch, Kelli R, Gomez, Elisa V, MS, Benichou, Olivier, Dr

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Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised controlled trial von Perkins, Gavin D, Prof, Lall, Ranjit, PhD, Quinn, Tom, Prof, Deakin, Charles D, Prof, Cooke, Matthew W, Prof, Horton, Jessica, MSc, Lamb, Sarah E, Prof, Slowther, Anne-Marie, DPhil, Woollard, Malcolm, Prof, Carson, Andy, FRCGP, Smyth, Mike, MSc, Whitfield, Richard, BSc, Williams, Amanda, MA, Pocock, Helen, MSc, Black, John J M, FCEM, Wright, John, FCEM, Han, Kyee, FCEM, Gates, Simon, Prof

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Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall surviv... von Ryan, Charles J, Prof, Smith, Matthew R, Prof, Fizazi, Karim, Prof, Saad, Fred, Prof, Mulders, Peter F A, Prof, Sternberg, Cora N, MD, Miller, Kurt, Prof, Logothetis, Christopher J, Prof, Shore, Neal D, MD, Small, Eric J, Prof, Carles, Joan, MD, Flaig, Thomas W, MD, Taplin, Mary-Ellen, MD, Higano, Celestia S, Prof, de Souza, Paul, Prof, de Bono, Johann S, Prof, Griffin, Thomas W, MD, De Porre, Peter, MD, Yu, Margaret K, MD, Park, Youn C, PhD, Li, Jinhui, PhD, Kheoh, Thian, PhD, Naini, Vahid, PharmD, Molina, Arturo, MD, Rathkopf, Dana E, MD

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Medical management with or without interventional therapy for unruptured brain arteriovenous malformations (ARUBA): a multicentre, non-blinded, randomised trial von Mohr, J P, Prof, Parides, Michael K, Prof, Stapf, Christian, Prof, Moquete, Ellen, RN, Moy, Claudia S, PhD, Overbey, Jessica R, MS, Salman, Rustam Al-Shahi, Prof, Vicaut, Eric, Prof, Young, William L, Prof, Houdart, Emmanuel, Prof, Cordonnier, Charlotte, Prof, Stefani, Marco A, Prof, Hartmann, Andreas, MD, von Kummer, Rüdiger, Prof, Biondi, Alessandra, Prof, Berkefeld, Joachim, Prof, Klijn, Catharina J M, MD, Harkness, Kirsty, MD, Libman, Richard, MD, Barreau, Xavier, MD, Moskowitz, Alan J, Prof

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Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials von Calfee, Carolyn S, Dr, Delucchi, Kevin, Prof, Parsons, Polly E, Prof, Thompson, B Taylor, Prof, Ware, Lorraine B, Prof, Matthay, Michael A, Prof

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Changes in health in England, with analysis by English regions and areas of deprivation, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 von Newton, John N, Prof, Briggs, Adam D M, MRCP, Murray, Christopher J L, Prof, Dicker, Daniel, BS, Foreman, Kyle J, MPH, Wang, Haidong, PhD, Naghavi, Mohsen, PhD, Forouzanfar, Mohammad H, PhD, Ohno, Summer Lockett, BA, Barber, Ryan M, BS, Vos, Theo, PhD, Stanaway, Jeffrey D, PhD, Schmidt, Jürgen C, Dott Med, Hughes, Andrew J, MSc, Fay, Derek F J, MSc, Ecob, Russell, MSc, Gresser, Charis, MSc, McKee, Martin, DSc, Rutter, Harry, MB Mchir, Abubakar, Ibrahim, Prof, Ali, Raghib, FRCP, Anderson, H Ross, Prof, Banerjee, Amitava, DPhil, Bennett, Derrick A, PhD, Bernabé, Eduardo, PhD, Bhui, Kamaldeep S, Prof, Biryukov, Stanley M, BS, Bourne, Rupert R, Prof, Brayne, Carol E G, Prof, Bruce, Nigel G, PhD, Brugha, Traolach S, Prof, Burch, Michael, MD, Capewell, Simon, Prof, Casey, Daniel, BA, Chowdhury, Rajiv, PhD, Coates, Matthew M, BS, Cooper, Cyrus, Prof, Critchley, Julia A, Prof, Dargan, Paul I, FRCP, Dherani, Mukesh K, PhD, Elliott, Paul, Prof, Ezzati, Majid, Prof, Fenton, Kevin A, MD, Fraser, Maya S, BA, Fürst, Thomas, PhD, Greaves, Felix, PhD, Green, Mark A, PhD, Gunnell, David J, Prof, Hannigan, Bernadette M, PhD, Hay, Roderick J, Prof, Hay, Simon I, Prof, Hemingway, Harry, Prof, Larson, Heidi J, PhD, Looker, Katharine J, PhD, Lunevicius, Raimundas, MD, Lyons, Ronan A, Prof, Marcenes, Wagner, Prof, Mason-Jones, Amanda J, PhD, Matthews, Fiona E, PhD, Moller, Henrik, Prof, Murdoch, Michele E, FRCP, Newton, Charles R, MD, Pearce, Neil, Prof, Piel, Frédéric B, PhD, Pope, Daniel, PhD, Rahimi, Kazem, DM, Rodriguez, Alina, Prof, Scarborough, Peter, DPhil, Schumacher, Austin E, BS, Shiue, Ivy, PhD, Smeeth, Liam, Prof, Tedstone, Alison, PhD, Valabhji, Jonathan, Prof, Williams, Hywel C, Prof, Wolfe, Charles D A, Prof, Woolf, Anthony D, Prof, Davis, Adrian C J, Prof

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Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials von Griffiths, Christopher E M, Prof, Reich, Kristian, Prof, Lebwohl, Mark, Prof, van de Kerkhof, Peter, Prof, Paul, Carle, Prof, Menter, Alan, MD, Cameron, Gregory S, PhD, Erickson, Janelle, PhD, Zhang, Lu, MS, Secrest, Roberta J, PhD, Ball, Susan, PhD, Braun, Daniel K, MD, Osuntokun, Olawale O, MD, Heffernan, Michael P, MD, Nickoloff, Brian J, MD, Papp, Kim, MD

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Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial von Fehrenbacher, Louis, Dr, Spira, Alexander, MD, Ballinger, Marcus, PhD, Kowanetz, Marcin, PhD, Vansteenkiste, Johan, Prof, Mazieres, Julien, Prof, Park, Keunchil, Prof, Smith, David, MD, Artal-Cortes, Angel, MD, Lewanski, Conrad, MD, Braiteh, Fadi, MD, Waterkamp, Daniel, MD, He, Pei, PhD, Zou, Wei, PhD, Chen, Daniel S, MD, Yi, Jing, PhD, Sandler, Alan, MD, Rittmeyer, Achim, MD

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Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial von Raal, Frederick J, Prof, Honarpour, Narimon, MD, Blom, Dirk J, MD, Hovingh, G Kees, MD, Xu, Feng, MS, Scott, Rob, MD, Wasserman, Scott M, MD, Stein, Evan A, Prof

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Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial von Davidson, Andrew J, Dr, Disma, Nicola, MD, de Graaff, Jurgen C, PhD, Withington, Davinia E, BM, Dorris, Liam, DClinPsy, Bell, Graham, MBChB, Stargatt, Robyn, PhD, Bellinger, David C, PhD, Schuster, Tibor, PhD, Arnup, Sarah J, MBiostat, Hardy, Pollyanna, MSc, Hunt, Rodney W, PhD, Takagi, Michael J, PhD, Giribaldi, Gaia, MD, Hartmann, Penelope L, BPsych, Salvo, Ida, MD, Morton, Neil S, MD, von Ungern Sternberg, Britta S, Prof, Locatelli, Bruno Guido, MD, Wilton, Niall, MBBS, Lynn, Anne, MD, Thomas, Joss J, MD, Polaner, David, Prof, Bagshaw, Oliver, FRCA, Szmuk, Peter, MD, Absalom, Anthony R, Prof, Frawley, Geoff, MBBS, Berde, Charles, Prof, Ormond, Gillian D, MSc, Marmor, Jacki, MEd, McCann, Mary Ellen, MD

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Meteorology in Polar Regions: Discussion von Close, Charles, M. Emm. de Margerie, Prof. Chapman, Walker, Gilbert, Mill, H. R., Davis, J. K., Brunt, David, Goodenough, William, Bonacina, L. C. W., Simpson, G. C.

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