AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling von Ferrarotto, Renata, Mishra, Vasudha, Herz, Elad, Yaacov, Adar, Solomon, Oz, Rauch, Rami, Mondshine, Adi, Motin, Maria, Leibovich-Rivkin, Tal, Davis, Matti, Kaye, Joel, Weber, Christopher R., Shen, Le, Pearson, Alexander T., Rosenberg, Ari J., Chen, Xiangying, Singh, Alka, Aster, Jon C., Agrawal, Nishant, Izumchenko, Evgeny

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The Mammalian Cos2 Homolog Kif7 Plays an Essential Role in Modulating Hh Signal Transduction during Development von Endoh-Yamagami, Setsu, Evangelista, Marie, Wilson, Deanna, Wen, Xiaohui, Theunissen, Jan-Willem, Phamluong, Khanhky, Davis, Matti, Scales, Suzie J., Solloway, Mark J., de Sauvage, Frederic J., Peterson, Andrew S.

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Abstract 4885: AL101 mediated tumor inhibition in Notch mutated ACC PDX models von ferrarotto, Renata, Alpert, Genia, Gluschnaider, Udi, Rauch, Rami, Mondshine, Adi, Solomon, Oz, Kramer, Bill, Izumchenko, Evgeny, Heymach, John, Vergara-Silva, Andrea, Aster, Jon, Davis, Matti

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AL101 mediated tumor inhibition in notch-altered TNBC PDX models von Broner, Esther Channah, Alpert, Genia, Gluschnaider, Udi, Mondshine, Adi, Solomon, Oz, Sloma, Ido, Rauch, Rami, Izumchenko, Evgeny, Aster, Jon Christopher, Davis, Matti

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A phase I study of AL101, a pan-NOTCH inhibitor, in patients (pts) with locally advanced or metastatic solid tumors von El-Khoueiry, Anthony B., Desai, Jayesh, Iyer, Swaminathan Padmanabhan, Gadgeel, Shirish M., Ramalingam, Suresh S., Horn, Leora, LoRusso, Patricia, Bajaj, Gaurav, Kollia, Georgia, Qi, Zhenhao, Basak, Shashwati, Fischer, Bruce S., Davis, Matti, Bedard, Philippe L.

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Spermatogenesis rescue in a mouse deficient for the ubiquitin ligase SCF β-TrCP by single substrate depletion von Kanarek, Naama, Horwitz, Elad, Mayan, Inbal, Leshets, Michael, Cojocaru, Gady, Davis, Matti, Tsuberi, Ben-Zion, Pikarsky, Eli, Pagano, Michele, Ben-Neriah, Yinon

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Identification of the receptor component of the IκBα-ubiquitin ligase von Ben-Neriah, Yinon, Yaron, Avraham, Hatzubai, Ada, Davis, Matti, Lavon, Iris, Amit, Sharon, Manning, Anthony M, Andersen, Jens S, Mann, Matthias, Mercurio, Frank

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BISFLUOROALKYL-1,4-BENZODIAZEPINONE COMPOUNDS FOR TREATING NOTCH-ACTIVATED BREAST CANCER von DAVIS, Matti

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BISFLUOROALKYL-1,4-BENZODIAZEPINONE COMPOUNDS FOR TREATING NOTCH-ACTIVATED BREAST CANCER von DAVIS, Matti

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COMBINATION COMPOSITIONS COMPRISING BISFLUOROALKYL-1,4- BENZODIAZEPINONE COMPOUNDS AND METHODS OF USE THEREOF von DAVIS, Matti

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BISFLUOROALKYL-1,4-BENZODIAZEPINONE COMPOUNDS FOR TREATING NOTCH-ACTIVATED BREAST CANCER von DAVIS, Matti

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BISFLUOROALKYL-1,4-BENZODIAZEPINONE COMPOUNDS FOR TREATING NOTCH-ACTIVATED BREAST CANCER von DAVIS, Matti

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Bisfluoroalkyl-1,4-benzodiazepinone compounds for treating Notch-activated breast cancer von DAVIS, Matti

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BISFLUOROALKYL-1,4-BENZODIAZEPIN ONE COMPOUNDS FOR TREATING NOTCH-ACTIVATED BREAST CANCER von DAVIS, Matti

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COMBINATION COMPOSITIONS COMPRISING BISFLUOROALKYL-1,4-BENZODIAZEPINONE COMPOUNDS AND METHODS OF USE THEREOF von DAVIS, Matti

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Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U von Davis, Matti, Hatzubai, Ada, Andersen, Jens S, Ben-Shushan, Etti, Fisher, Gregory Zvi, Yaron, Avraham, Bauskin, Asne, Mercurio, Frank, Mann, Matthias, Ben-Neriah, Yinon

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COMBINATION COMPOSITIONS COMPRISING BISFLUOROALKYL-1,4- BENZODIAZEPINONE COMPOUNDS AND METHODS OF USE THEREOF von DAVIS, Matti

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COMBINATION COMPOSITIONS COMPRISING BISFLUOROALKYL-1,4- BENZODIAZEPINONE COMPOUNDS AND METHODS OF USE THEREOF von Davis, Matti

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Combination compositions comprising bisfluoroalkyl-1,4- benzodiazepinone compounds and methods of use thereof von DAVIS, Matti

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COMBINATION COMPOSITIONS COMPRISING BISFLUOROALKYL-1,4- BENZODIAZEPINONE COMPOUNDS AND METHODS OF USE THEREOF von DAVIS, Matti

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