An FDA/CDER perspective on nonclinical testing strategies: Classical toxicology approaches and new approach methodologies (NAMs) von Avila, Amy M., Bebenek, Ilona, Bonzo, Jessica A., Bourcier, Todd, Davis Bruno, Karen L., Carlson, David B., Dubinion, John, Elayan, Ikram, Harrouk, Wafa, Lee, Shwu-Luan, Mendrick, Donna L., Merrill, Jill C., Peretz, Jackye, Place, Emily, Saulnier, Muriel, Wange, Ronald L., Yao, Jia, Zhao, Dong, Brown, Paul C.

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Optimizing the detection of N-nitrosamine mutagenicity in the Ames test von Heflich, Robert H., Bishop, Michelle E., Mittelstaedt, Roberta A., Yan, Jian, Guerrero, Sharon K., Sims, Audrey M., Mitchell, Kamela, Moore, Nyosha, Li, Xilin, Mei, Nan, Elespuru, Rosalie K., King, Sruthi T., Keire, David A., Kruhlak, Naomi L., Dorsam, Robert T., Raw, Andre S., Davis Bruno, Karen L., McGovern, Timothy J., Atrakchi, Aisar H.

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Genotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell models von Seo, Ji-Eun, Yu, Joshua Z., Xu, Hannah, Li, Xilin, Atrakchi, Aisar H., McGovern, Timothy J., Bruno, Karen L. Davis, Mei, Nan, Heflich, Robert H., Guo, Xiaoqing

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Implementation of the principles of the 3Rs of animal testing at CDER: Past, present and future von Wange, Ronald L., Brown, Paul C., Davis-Bruno, Karen L.

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Novel effects of nitric oxide von Davis, K. L., Martin, E., Turko, I. V., Murad, F.

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Scholarly Inquiry and Research: An assessment of graduate dental hygiene schools' requirements von Brungardt-Davis, Karen L, Mitchell, Tanya Villalpando, Van Ness, Christopher J, Gadbury-Amyot, Cynthia C

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Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450s von Li, Xilin, He, Xiaobo, Le, Yuan, Guo, Xiaoqing, Bryant, Matthew S., Atrakchi, Aisar H., McGovern, Timothy J., Davis-Bruno, Karen L., Keire, David A., Heflich, Robert H., Mei, Nan

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Mutagenicity and genotoxicity evaluation of 15 nitrosamine drug substance-related impurities in human TK6 cells von Li, Xilin, Le, Yuan, Guo, Xiaoqing, King, Sruthi T., Dorsam, Robert T., Atrakchi, Aisar H., McGovern, Timothy J., Davis-Bruno, Karen L., Keire, David A., Heflich, Robert H., Mei, Nan

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Revisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays von Li, Xilin, Le, Yuan, Seo, Ji-Eun, Guo, Xiaoqing, Li, Yuxi, Chen, Si, Mittelstaedt, Roberta A., Moore, Nyosha, Guerrero, Sharon, Sims, Audrey, King, Sruthi T., Atrakchi, Aisar H., McGovern, Timothy J., Davis-Bruno, Karen L., Keire, David A., Elespuru, Rosalie K., Heflich, Robert H., Mei, Nan

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A Regulatory Perspective on Issues and Approaches in Characterizing Human Metabolites von Davis-Bruno, Karen L., Atrakchi, Aisar

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Esmolol and cardiopulmonary bypass during reperfusion reduce myocardial infarct size in dogs von Geissler, Hans J, Davis, Karen L, Buja, L.Maximilian, Laine, Glen A, Brennan, Michael L, Mehlhorn, Uwe, Allen, Steven J

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Normothermic continuous antegrade blood cardioplegia does not prevent myocardial edema and cardiac dysfunction von Mehlhorn, U, Allen, S J, Adams, D L, Davis, K L, Gogola, G R, de Vivie, E R, Laine, G A

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The Urban Paraeducator Goes to College von Wall, Shavaun, Davis, Karen L., Winkler Crowley, Abby L., White, Laura L.

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Cooling Gradients and Formation of Gaseous Microemboli With Cardiopulmonary Bypass: An Echocardiographic Study von Geissler, Hans J, Allen, Steven J, Mehlhorn, Uwe, Davis, Karen L, de Vivie, E.Rainer, Kurusz, Mark, Butler, Bruce D

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Contamination of lymph from the major prenodal cardiac lymphatic in dogs von Geissler, Hans J, Davis, Karen L, Laine, Glen A, Brennan, Michael L, Mehlhorn, Uwe, Allen, Steven J

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Myocardial Fluid Balance in Acute Hypertension von Mehlhorn, Uwe, Davis, Karen L., Laine, Glen A., Geissler, Hans J., Allen, Steven J.

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Effect of body repositioning after venous air embolism. An echocardiographic study von Geissler, H. J., Allen, S. J., Mehlhorn, U., Davis, K. L., Morris, W. P., Butler, B. D.

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Cardiac surgical conditions induced by β-blockade: Effect on myocardial fluid balance von Mehlhorn, Uwe, Allen, Steven J., Adams, Deborah L., Davis, Karen L., Gogola, Gloria R., Warters, R. David

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Expression and characterization of CD4-IgG2, a novel heterotetramer that neutralizes primary HIV type 1 isolates von ALLAWAY, G. P, DAVIS-BRUNO, K. L, MADDON, P. J, BEAUDRY, G. A, GARCIA, E. B, WONG, E. L, RYDER, A. M, HASEL, K. W, GAUDUIN, M.-C, KOUP, R. A, MCDOUGAL, J. S

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Myocardial protection with high-dose β-blockade in acute myocardial ischemia von GEISSLER, H. J, DAVIS, K. L, LAINE, G. A, OSTRIN, E. J, MEHLHORN, U, HEKMAT, K, WARTERS, R. D, ALLEN, S. J

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