Pharmacokinetic Properties of Infliximab in Children and Adults with Crohn's Disease: A Retrospective Analysis of Data from 2 Phase III Clinical Trials von Fasanmade, Adedigbo A., PhD, Adedokun, Omoniyi J., MS, Blank, Marion, PhD, Zhou, Honghui, PhD, Davis, Hugh M., PhD

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Clinical impact of concomitant immunomodulators on biologic therapy: Pharmacokinetics, immunogenicity, efficacy and safety von Xu, Zhenhua, Davis, Hugh M., Zhou, Honghui

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Interspecies Scaling of Therapeutic Monoclonal Antibodies: Initial Look von Ling, Jie, Zhou, Honghui, Jiao, Qun, Davis, Hugh M.

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Comparative analysis of lymphocyte activation marker expression and cytokine secretion profile in stimulated human peripheral blood mononuclear cell cultures: an in vitro model to... von Reddy, Manjula, Eirikis, Edward, Davis, Cuc, Davis, Hugh M., Prabhakar, Uma

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Pharmacokinetics, pharmacodynamics and safety of a human anti‐IL‐6 monoclonal antibody (sirukumab) in healthy subjects in a first‐in‐human study von Xu, Zhenhua, Bouman‐Thio, Esther, Comisar, Craig, Frederick, Bart, Van Hartingsveldt, Bart, Marini, Joseph C., Davis, Hugh M., Zhou, Honghui

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Modification of the Fc Region of a Human Anti‐oncostatin M Monoclonal Antibody for Higher Affinity to FcRn Receptor and Extension of Half‐life in Cynomolgus Monkeys von Nnane, Ivo P., Han, Chao, Jiao, Qun, Tam, Susan H., Davis, Hugh M., Xu, Zhenhua

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Mechanistic Pharmacokinetic/Target Engagement/Pharmacodynamic (PK/TE/PD) Modeling in Deciphering Interplay Between a Monoclonal Antibody and Its Soluble Target in Cynomolgus Monkey... von Wang, Weirong, Wang, Xiaofeng, Doddareddy, Rajitha, Fink, Damien, McIntosh, Thomas, Davis, Hugh M., Zhou, Honghui

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Subcutaneous Bioavailability of Golimumab at 3 Different Injection Sites in Healthy Subjects von Xu, Zhenhua, Wang, Qingmin, Zhuang, Yanli, Frederick, Bart, Yan, Hong, Bouman-Thio, Esther, Marini, Joseph C., Keen, Monica, Snead, David, Davis, Hugh M., Zhou, Honghui

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Non‐Clinical Pharmacokinetics, Prediction of Human Pharmacokinetics and First‐in‐Human Dose Selection for CNTO 5825, an Anti‐Interleukin‐13 Monoclonal Antibody von Nnane, Ivo P., Xu, Zhenhua, Zhou, Honghui, Davis, Hugh M.

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Golimumab Pharmacokinetics After Repeated Subcutaneous and Intravenous Administrations in Patients with Rheumatoid Arthritis and the Effect of Concomitant Methotrexate: An Open-Lab... von Zhuang, Yanli, PhD, Xu, Zhenhua, PhD, FCP, Frederick, Bart, BS, de Vries, Dick E., MD, Ford, Joyce A., MS, Keen, Monica, BS, Doyle, Mittie K., MD, Petty, Kevin J., MD, PhD, Davis, Hugh M., PhD, Zhou, Honghui, PhD, FCP

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Pharmacokinetics and Exposure Response Relationships of Ustekinumab in Patients With Crohn's Disease von Adedokun, Omoniyi J., Xu, Zhenhua, Gasink, Christopher, Jacobstein, Douglas, Szapary, Philippe, Johanns, Jewel, Gao, Long-Long, Davis, Hugh M., Hanauer, Stephen B., Feagan, Brian G., Ghosh, Subrata, Sandborn, William J.

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CDX-585, a Bispecific Antibody with Dual Targeting of ILT4 and PD-1 Checkpoint Pathways von Murphy, Michael B., Vitale, Laura, Xia, Shukai, Peng, Zeyu, O’Neill, Thomas, Lillquist, Jay, Wasiuk, Anna, Weidlick, Jeff, Widger, Jenifer, Mills-Chen, Laura, Crocker, Andrea, Patterson, Colleen, Boyer, James, Baronas, April R., Chen, Mingjiu, Davis, Hugh M., Ma, Mark, Goldstein, Joel, Thomas, Lawrence J., Alvarado, Diego, Marsh, Henry C., Keler, Tibor

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Pharmacokinetic Bridging Approach for Developing Biologics-delivery Devices: A Case Study With a Golimumab Autoinjector von Xu, Zhenhua, PhD, Marciniak, Stanley J., MBA, Frederick, Bart, Kim, Lilianne, PhD, Zhuang, Yanli, PhD, Davis, Hugh M., PhD, Zhou, Honghui, PhD

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Association Between Serum Concentration of Infliximab and Efficacy in Adult Patients With Ulcerative Colitis von Adedokun, Omoniyi J, Sandborn, William J, Feagan, Brian G, Rutgeerts, Paul, Xu, Zhenhua, Marano, Colleen W, Johanns, Jewel, Zhou, Honghui, Davis, Hugh M, Cornillie, Freddy, Reinisch, Walter

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Utilizing pharmacokinetics/pharmacodynamics modeling to simultaneously examine free CCL2, total CCL2 and carlumab (CNTO 888) concentration time data von Fetterly, Gerald J., Aras, Urvi, Meholick, Patricia D., Takimoto, Chris, Seetharam, Shobha, McIntosh, Thomas, de Bono, Johann S., Sandhu, Shahneen K., Tolcher, Anthony, Davis, Hugh M., Zhou, Honghui, Puchalski, Thomas A.

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Phase I Evaluation of a Fully Human Anti–αv Integrin Monoclonal Antibody (CNTO 95) in Patients with Advanced Solid Tumors von MULLAMITHA, Saifee A, TON, Nhuan C, HOPE, Lynn, VALLE, Juan W, RADFORD, John A, LAWRANCE, Jeremy, SAUNDERS, Mark P, MUNTEANU, Mihaela C, NAKADA, Marian T, NEMETH, Jeffrey A, DAVIS, Hugh M, QUN JIAO, PARKER, Geoff J. M, PRABHAKAR, Uma, ZHIHUI LANG, CORRINGHAM, Robert E, BECKMAN, Robert A, JAYSON, Gordon C, JACKSON, Alan, JULYAN, Peter J, ROBERTS, Caleb, BUONACCORSI, Gio A, WATSON, Yvonne, DAVIES, Karen, CHEUNG, Sue

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Safety, tolerability and pharmacokinetics of a human anti‐interleukin‐13 monoclonal antibody (CNTO 5825) in an ascending single‐dose first‐in‐human study von Hartingsveldt, Bart, Nnane, Ivo P., Bouman‐Thio, Esther, Loza, Matthew J., Piantone, Alexa, Davis, Hugh M., Petty, Kevin J.

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Antibody constructs in cancer therapy : Protein engineering strategies to improve exposure in solid tumors von BECKMAN, Robert A, WEINER, Louis M, DAVIS, Hugh M

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Pharmacokinetic and Pharmacodynamic Modeling of an Anti-Interleukin-6 Chimeric Monoclonal Antibody (Siltuximab) in Patients with Metastatic Renal Cell Carcinoma von PUCHALSKI, Thomas, PRABHAKAR, Uma, QUN JIAO, BERNS, Birge, DAVIS, Hugh M

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Lack of Racial Differences in the Pharmacokinetics of Subcutaneous Golimumab in Healthy Japanese and Caucasian Male Subjects von Ling, Jie, Lyn, Sally, Xu, Zhenhua, Achira, Meguru, Bouman-Thio, Esther, Shishido, Akira, Ford, Joyce, Shankar, Gopi, Wagner, Carrie, Kim, Kenneth T., Davis, Hugh M., Zhou, Honghui

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