Abstract 2708: Development of an individualized 3D transport model of topotecan for a patient-derived orthotopic xenograft model of pediatric neuroblastoma von Shirinifard, Abbas, Thiagarajan, Suresh, Patel, Yogesh T., Davis, Abigail D., Jacus, Megan O., Throm, Stacy L., Roberts, Jessica, Daryani, Vinay, Stewart, Clinton F., Sablauer, András

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Simvastatin Hydroxy Acid Fails to Attain Sufficient Central Nervous System Tumor Exposure to Achieve a Cytotoxic Effect: Results of a Preclinical Cerebral Microdialysis Study von Patel, Yogesh T, Jacus, Megan O, Davis, Abigail D, Boulos, Nidal, Turner, David C, Vuppala, Pradeep K, Freeman, 3rd, Burgess B, Gilbertson, Richard J, Stewart, Clinton F

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Preclinical examination of clofarabine in pediatric ependymoma: intratumoral concentrations insufficient to warrant further study von Patel, Yogesh T., Jacus, Megan O., Boulos, Nidal, Dapper, Jason D., Davis, Abigail D., Vuppala, Pradeep K., Freeman, Burgess B., Mohankumar, Kumarasamypet M., Throm, Stacy L., Gilbertson, Richard J., Stewart, Clinton F.

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Observational Evaluations of Mice during Cerebral Microdialysis for Pediatric Brain Tumor Research von Jacus, Megan O, Rahija, Richard J., Davis, Abigail D, Throm, Stacy L, Stewart, Clinton F

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Abstract A33: An individualized predictive 3D model of tumor response to topotecan for a patient-derived orthotopic xenograft model of pediatric neuroblastoma von Shirinifard, Abbas, Thiagarajan, Suresh, Patel, Yogesh T., Davis, Abigail D., Jacus, Megan O., Roberts, Jessica, Stewart, Clinton F., Sablauer, András

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Abstract 1496: Quantification of tumor blood perfusion of an orthotopic mouse model of neuroblastoma using nonlinear contrast-enhanced ultrasound imaging von Thiagarajan, Suresh, Shirinifard, Abbas, Jacus, Megan O., Davis, Abigail D., Patel, Yogesh T., Throm, Stacy L., Daryani, Vinay, Stewart, Clinton F., Sablauer, András

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Abstract 4519: Development of a whole body physiologically-based pharmacokinetic (PBPK) model with individualized tumor compartment for topotecan (TPT) in mice bearing neuroblastom... von Patel, Yogesh T., Jacus, Megan O., Shirinifard, Abbas, Davis, Abigail D., Thiagarajan, Suresh, Throm, Stacy L., Daryani, Vinay M., Sablauer, Andras, Stewart, Clinton F.

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Abstract 4645: Clofarabine, a potent anticancer compound with limited penetration in an orthotopic murine model of ependymoma von Patel, Yogesh T., Jacus, Megan O., Davis, Abigail D., Vuppala, Pradeep, Dapper, Jason D., Freeman, Burgess B., Boulos, Nidal, Throm, Stacy L., Gilbertson, Richard J., Stewart, Clinton F.

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Modulating PCAF/GCN5 Immune Cell Function through a PROTAC Approach von Bassi, Zuni I, Fillmore, Martin C, Miah, Afjal H, Chapman, Trevor D, Maller, Claire, Roberts, Emma J, Davis, Lauren C, Lewis, Darcy E, Galwey, Nicholas W, Waddington, Kirsty E, Parravicini, Valentino, Macmillan-Jones, Abigail L, Gongora, Celine, Humphreys, Philip G, Churcher, Ian, Prinjha, Rab K, Tough, David F

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The role of therapist training in the implementation of psychosocial treatments: A review and critique with recommendations von Herschell, Amy D., Kolko, David J., Baumann, Barbara L., Davis, Abigail C.

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Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression von Cuomo, Anna S. E., Seaton, Daniel D., McCarthy, Davis J., Martinez, Iker, Bonder, Marc Jan, Garcia-Bernardo, Jose, Amatya, Shradha, Madrigal, Pedro, Isaacson, Abigail, Buettner, Florian, Knights, Andrew, Natarajan, Kedar Nath, Vallier, Ludovic, Marioni, John C., Chhatriwala, Mariya, Stegle, Oliver

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Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients von Suthar, Mehul S., Zimmerman, Matthew G., Kauffman, Robert C., Mantus, Grace, Linderman, Susanne L., Hudson, William H., Vanderheiden, Abigail, Nyhoff, Lindsay, Davis, Carl W., Adekunle, Oluwaseyi, Affer, Maurizio, Sherman, Melanie, Reynolds, Stacian, Verkerke, Hans P., Alter, David N., Guarner, Jeannette, Bryksin, Janetta, Horwath, Michael C., Arthur, Connie M., Saakadze, Natia, Smith, Geoffrey H., Edupuganti, Srilatha, Scherer, Erin M., Hellmeister, Kieffer, Cheng, Andrew, Morales, Juliet A., Neish, Andrew S., Stowell, Sean R., Frank, Filipp, Ortlund, Eric, Anderson, Evan J., Menachery, Vineet D., Rouphael, Nadine, Mehta, Aneesh K., Stephens, David S., Ahmed, Rafi, Roback, John D., Wrammert, Jens

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Atrial natriuretic peptide is negatively regulated by microRNA-425 von Arora, Pankaj, Wu, Connie, Khan, Abigail May, Bloch, Donald B, Davis-Dusenbery, Brandi N, Ghorbani, Anahita, Spagnolli, Ester, Martinez, Andrew, Ryan, Allicia, Tainsh, Laurel T, Kim, Samuel, Rong, Jian, Huan, Tianxiao, Freedman, Jane E, Levy, Daniel, Miller, Karen K, Hata, Akiko, Del Monte, Federica, Vandenwijngaert, Sara, Swinnen, Melissa, Janssens, Stefan, Holmes, Tara M, Buys, Emmanuel S, Bloch, Kenneth D, Newton-Cheh, Christopher, Wang, Thomas J

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Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge von Muruato, Antonio, Vu, Michelle N, Johnson, Bryan A, Davis-Gardner, Meredith E, Vanderheiden, Abigail, Lokugamage, Kumari, Schindewolf, Craig, Crocquet-Valdes, Patricia A, Langsjoen, Rose M, Plante, Jessica A, Plante, Kenneth S, Weaver, Scott C, Debbink, Kari, Routh, Andrew L, Walker, David, Suthar, Mehul S, Shi, Pei-Yong, Xie, Xuping, Menachery, Vineet D

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Intramolecular Diels–Alder Reaction of a Biphenyl Group in a Strained meta-Quaterphenylene Acetylene von Mittal, Komal, Pham, Ashley V., Davis, Amanda G., Richardson, Abigail D., De Hoe, Clement, Dean, Ryan T., Baird, Vi, McDonald, Ashley Ringer, Frantz, Derik K.

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Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension von Forrest, Abigail S, Joyce, Talia C, Huebner, Marissa L, Ayon, Ramon J, Wiwchar, Michael, Joyce, John, Freitas, Natalie, Davis, Alison J, Ye, Linda, Duan, Dayue D, Singer, Cherie A, Valencik, Maria L, Greenwood, Iain A, Leblanc, Normand

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Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit von Hall, Matthew D, Anderson, James M, Anderson, Annaliesa, Baker, David, Bradner, Jay, Brimacombe, Kyle R, Campbell, Elizabeth A, Corbett, Kizzmekia S, Carter, Kara, Cherry, Sara, Chiang, Lillian, Cihlar, Tomas, de Wit, Emmie, Denison, Mark, Disney, Matthew, Fletcher, Courtney V, Ford-Scheimer, Stephanie L, Götte, Matthias, Grossman, Abigail C, Hayden, Frederick G, Hazuda, Daria J, Lanteri, Charlotte A, Marston, Hilary, Mesecar, Andrew D, Moore, Stephanie, Nwankwo, Jennifer O, O’Rear, Jules, Painter, George, Singh Saikatendu, Kumar, Schiffer, Celia A, Sheahan, Timothy P, Shi, Pei-Yong, Smyth, Hugh D, Sofia, Michael J, Weetall, Marla, Weller, Sandra K, Whitley, Richard, Fauci, Anthony S, Austin, Christopher P, Collins, Francis S, Conley, Anthony J, Davis, Mindy I

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Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis von Yonker, Lael M., Swank, Zoe, Bartsch, Yannic C., Burns, Madeleine D., Kane, Abigail, Boribong, Brittany P., Davis, Jameson P., Loiselle, Maggie, Novak, Tanya, Senussi, Yasmeen, Cheng, Chi-An, Burgess, Eleanor, Edlow, Andrea G., Chou, Janet, Dionne, Audrey, Balaguru, Duraisamy, Lahoud-Rahme, Manuella, Arditi, Moshe, Julg, Boris, Randolph, Adrienne G., Alter, Galit, Fasano, Alessio, Walt, David R.

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Effects of religion, politics and distance to providers on HPV vaccine attitudes and intentions of parents in rural Utah von Lee, Abigail A, Skyles, Ty J, Jensen, Jamie L, Ord, Brandon, Davis, Spencer C, East, Matthew J, Asay, A Eli, Obray, Acelan M, Syndergaard, Tess, Davis, Tyler, Nielson, Bryce U, Larson, Ruth J, Miner, Dashiell S, Hinton, Kaitlyn, Zentz, Lydia, Busacker, Lydia, Poole, Brian D

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Revealing the complex genetic architecture of obsessive–compulsive disorder using meta-analysis von Arnold, Paul D, Askland, Kathleen D, Barlassina, Cristina, Bellodi, Laura, Bienvenu, O J, Black, Donald, Bloch, Michael, Brentani, Helena, Burton, Christie L, Camarena, Beatriz, Cappi, Carolina, Cath, Danielle, Cavallini, Maria, Conti, David, Cook, Edwin, Coric, Vladimir, Cullen, Bernadette A, Cusi, Danielle, Davis, Lea K, Delorme, Richard, Denys, Damiaan, Derks, Eske, Eapen, Valsamma, Edlund, Christopher, Erdman, Lauren, Falkai, Peter, Figee, Ma, Fyer, Abigail J, Geller, Daniel A, Goes, Fernando S, Grabe, Hans, Grados, Marcos A, Greenberg, Benjamin D, Grünblatt, Edna, Guo, Wei, Hanna, Gregory L, Hemmings, Sian, Hounie, Ana G, Jenicke, Michael, Keenan, Clare, Kennedy, James, Khramtsova, Ekaterina A, Konkashbaev, Anuar, Knowles, James A, Krasnow, Janice, Lange, Cristophe, Lanzagorta, Nuria, Leboyer, Marion, Lennertz, Leonhard, Li, Bingbin, Liang, K-Y, Lochner, Christine, Macciardi, Fabio, Maher, Brion, Maier, Wolfgang, Marconi, Maurizio, Mathews, Carol A, Matthesien, Manuel, McCracken, James T, McLaughlin, Nicole C, Miguel, Euripedes C, Moessner, Rainald, Murphy, Dennis L, Neale, Benjamin, Nestadt, Gerald, Nestadt, Paul, Nicolini, Humberto, Nurmi, Ericka, Osiecki, Lisa, Pauls, David L, Piacentini, John, Posthuma, Danielle, Pulver, Ann E, Qin, H-D, Rasmussen, Steven A, Rauch, Scott, Richter, Margaret A, Riddle, Mark A, Ripke, Stephan, Ruhrmann, Stephan, Sampaio, Aline S, Samuels, Jack F, Scharf, Jeremiah M, Shugart, Yin Yao, Smit, Jan, Stein, Daniel, Stewart, S Evelyn, Turiel, Maurizio, Vallada, Homero, Veenstra-VanderWeele, Jeremy, Wagner, Michael, Walitza, Susanne, Wang, Y, Wendland, Jens, Vulink, Nienke, Yu, Dongmei, Zai, Gwyneth

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