The role of the PI3K-AKT pathway in melanoma von Davies, Michael A

Volltext

Neoadjuvant relatlimab and nivolumab in resectable melanoma von Amaria, Rodabe N., Postow, Michael, Burton, Elizabeth M., Tetzlaff, Michael T., Ross, Merrick I., Torres-Cabala, Carlos, Glitza, Isabella C., Duan, Fei, Milton, Denái R., Busam, Klaus, Simpson, Lauren, McQuade, Jennifer L., Wong, Michael K., Gershenwald, Jeffrey E., Lee, Jeffrey E., Goepfert, Ryan P., Keung, Emily Z., Fisher, Sarah B., Betof-Warner, Allison, Shoushtari, Alexander N., Callahan, Margaret, Coit, Daniel, Bartlett, Edmund K., Bello, Danielle, Momtaz, Parisa, Nicholas, Courtney, Gu, Aidi, Zhang, Xuejun, Korivi, Brinda Rao, Patnana, Madhavi, Patel, Sapna P., Diab, Adi, Lucci, Anthony, Prieto, Victor G., Davies, Michael A., Allison, James P., Sharma, Padmanee, Wargo, Jennifer A., Ariyan, Charlotte, Tawbi, Hussein A.

Volltext

Silicon Nanowire Sensors Enable Diagnosis of Patients via Exhaled Breath von Shehada, Nisreen, Cancilla, John C, Torrecilla, Jose S, Pariente, Enrique S, Brönstrup, Gerald, Christiansen, Silke, Johnson, Douglas W, Leja, Marcis, Davies, Michael P. A, Liran, Ori, Peled, Nir, Haick, Hossam

Volltext

Factors predictive of response, disease progression, and overall survival after dabrafenib and trametinib combination treatment: a pooled analysis of individual patient data from r... von Long, Georgina V, Prof, Grob, Jean-Jacques, Prof, Nathan, Paul, MD, Ribas, Antoni, Prof, Robert, Caroline, MD, Schadendorf, Dirk, Prof, Lane, Stephen R, MSc, Mak, Carmen, PhD, Legenne, Philippe, MD, Flaherty, Keith T, Prof, Davies, Michael A, MD

Volltext

Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials von Meric-Bernstam, Funda, Brusco, Lauren, Shaw, Kenna, Horombe, Chacha, Kopetz, Scott, Davies, Michael A, Routbort, Mark, Piha-Paul, Sarina A, Janku, Filip, Ueno, Naoto, Hong, David, De Groot, John, Ravi, Vinod, Li, Yisheng, Luthra, Raja, Patel, Keyur, Broaddus, Russell, Mendelsohn, John, Mills, Gordon B

Volltext

Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma von Ma, Xiao-Hong, Piao, Sheng-Fu, Dey, Souvik, McAfee, Quentin, Karakousis, Giorgos, Villanueva, Jessie, Hart, Lori S, Levi, Samuel, Hu, Janice, Zhang, Gao, Lazova, Rossitza, Klump, Vincent, Pawelek, John M, Xu, Xiaowei, Xu, Wei, Schuchter, Lynn M, Davies, Michael A, Herlyn, Meenhard, Winkler, Jeffrey, Koumenis, Constantinos, Amaravadi, Ravi K

Volltext

Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial von Long, Georgina V, Dr, Trefzer, Uwe, MD, Davies, Michael A, MD, Kefford, Richard F, Prof, Ascierto, Paolo A, MD, Chapman, Paul B, MD, Puzanov, Igor, MD, Hauschild, Axel, MD, Robert, Caroline, PhD, Algazi, Alain, MD, Mortier, Laurent, Prof, Tawbi, Hussein, PhD, Wilhelm, Tabea, MD, Zimmer, Lisa, MD, Switzky, Julie, MSN, Swann, Suzanne, PhD, Martin, Anne-Marie, PhD, Guckert, Mary, MSN, Goodman, Vicki, MD, Streit, Michael, MD, Kirkwood, John M, Prof, Schadendorf, Dirk, Prof

Volltext

Navigating the Therapeutic Complexity of PI3K Pathway Inhibition in Melanoma von KWONG, Lawrence N, DAVIES, Michael A

Volltext

NRAS mutation status is an independent prognostic factor in metastatic melanoma von Jakob, John A., Bassett, Roland L., Ng, Chaan S., Curry, Jonathan L., Joseph, Richard W., Alvarado, Gladys C., Rohlfs, Michelle L., Richard, Jessie, Gershenwald, Jeffrey E., Kim, Kevin B., Lazar, Alexander J., Hwu, Patrick, Davies, Michael A.

Volltext

Regulation, Role, and Targeting of Akt in Cancer von DAVIES, Michael A

Volltext

Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition von Ngo, Bryan, Kim, Eugenie, Osorio-Vasquez, Victoria, Doll, Sophia, Bustraan, Sophia, Liang, Roger J, Luengo, Alba, Davidson, Shawn M, Ali, Ahmed, Ferraro, Gino B, Fischer, Grant M, Eskandari, Roozbeh, Kang, Diane S, Ni, Jing, Plasger, Ariana, Rajasekhar, Vinagolu K, Kastenhuber, Edward R, Bacha, Sarah, Sriram, Roshan K, Stein, Benjamin D, Bakhoum, Samuel F, Snuderl, Matija, Cotzia, Paolo, Healey, John H, Mainolfi, Nello, Suri, Vipin, Friedman, Adam, Manfredi, Mark, Sabatini, David M, Jones, Drew R, Yu, Min, Zhao, Jean J, Jain, Rakesh K, Keshari, Kayvan R, Davies, Michael A, Vander Heiden, Matthew G, Hernando, Eva, Mann, Matthias, Cantley, Lewis C, Pacold, Michael E

Volltext

ALK Fusion Partners Impact Response to ALK Inhibition: Differential Effects on Sensitivity, Cellular Phenotypes, and Biochemical Properties von Childress, Merrida A, Himmelberg, Stephen M, Chen, Huiqin, Deng, Wanleng, Davies, Michael A, Lovly, Christine M

Volltext

AKT1 Activation Promotes Development of Melanoma Metastases von Cho, Joseph H., Robinson, James P., Arave, Rowan A., Burnett, William J., Kircher, David A., Chen, Guo, Davies, Michael A., Grossmann, Allie H., VanBrocklin, Matthew W., McMahon, Martin, Holmen, Sheri L.

Volltext

mTORC1 Activation Blocks BrafV600E-Induced Growth Arrest but Is Insufficient for Melanoma Formation von Damsky, William, Micevic, Goran, Meeth, Katrina, Muthusamy, Viswanathan, Curley, David P., Santhanakrishnan, Manjula, Erdelyi, Ildiko, Platt, James T., Huang, Laura, Theodosakis, Nicholas, Zaidi, M. Raza, Tighe, Scott, Davies, Michael A., Dankort, David, McMahon, Martin, Merlino, Glenn, Bardeesy, Nabeel, Bosenberg, Marcus

Volltext

Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma von AbuHammad, Shatha, Cullinane, Carleen, Martin, Claire, Bacolas, Zoe, Ward, Teresa, Chen, Huiqin, Slater, Alison, Ardley, Kerry, Kirby, Laura, Chan, Keefe T., Brajanovski, Natalie, Smith, Lorey K., Rao, Aparna D., Lelliott, Emily J., Kleinschmidt, Margarete, Vergara, Ismael A., Papenfuss, Anthony T., Lau, Peter, Ghosh, Prerana, Haupt, Sue, Haupt, Ygal, Sanij, Elaine, Poortinga, Gretchen, Pearson, Richard B., Falk, Hendrik, Curtis, David J., Stupple, Paul, Devlin, Mark, Street, Ian, Davies, Michael A., McArthur, Grant A., Sheppard, Karen E.

Volltext

Immune checkpoint inhibitor related myasthenia gravis: single center experience and systematic review of the literature von Safa, Houssein, Johnson, Daniel H, Trinh, Van Anh, Rodgers, Theresa E, Lin, Heather, Suarez-Almazor, Maria E, Fa’ak, Faisal, Saberian, Chantal, Yee, Cassian, Davies, Michael A, Tummala, Sudhakar, Woodman, Karin, Abdel-Wahab, Noha, Diab, Adi

Volltext

Potential genetic modifiers for somatic EGFR mutation in lung cancer: a meta-analysis and literature review von Cheng, Yue I, Gan, Yun Cui, Liu, Dan, Davies, Michael P A, Li, Wei Min, Field, John K

Volltext

Tumor-associated B-cells induce tumor heterogeneity and therapy resistance von Somasundaram, Rajasekharan, Zhang, Gao, Fukunaga-Kalabis, Mizuho, Perego, Michela, Krepler, Clemens, Xu, Xiaowei, Wagner, Christine, Hristova, Denitsa, Zhang, Jie, Tian, Tian, Wei, Zhi, Liu, Qin, Garg, Kanika, Griss, Johannes, Hards, Rufus, Maurer, Margarita, Hafner, Christine, Mayerhöfer, Marius, Karanikas, Georgios, Jalili, Ahmad, Bauer-Pohl, Verena, Weihsengruber, Felix, Rappersberger, Klemens, Koller, Josef, Lang, Roland, Hudgens, Courtney, Chen, Guo, Tetzlaff, Michael, Wu, Lawrence, Frederick, Dennie Tompers, Scolyer, Richard A., Long, Georgina V., Damle, Manashree, Ellingsworth, Courtney, Grinman, Leon, Choi, Harry, Gavin, Brian J., Dunagin, Margaret, Raj, Arjun, Scholler, Nathalie, Gross, Laura, Beqiri, Marilda, Bennett, Keiryn, Watson, Ian, Schaider, Helmut, Davies, Michael A., Wargo, Jennifer, Czerniecki, Brian J., Schuchter, Lynn, Herlyn, Dorothee, Flaherty, Keith, Herlyn, Meenhard, Wagner, Stephan N.

Volltext

Distinct molecular and immune hallmarks of inflammatory arthritis induced by immune checkpoint inhibitors for cancer therapy von Kim, Sang T., Chu, Yanshuo, Misoi, Mercy, Suarez-Almazor, Maria E., Tayar, Jean H., Lu, Huifang, Buni, Maryam, Kramer, Jordan, Rodriguez, Emma, Hussain, Zulekha, Neelapu, Sattva S., Wang, Jennifer, Shah, Amishi Y., Tannir, Nizar M., Campbell, Matthew T., Gibbons, Don L., Cascone, Tina, Lu, Charles, Blumenschein, George R., Altan, Mehmet, Lim, Bora, Valero, Vincente, Loghin, Monica E., Tu, Janet, Westin, Shannon N., Naing, Aung, Garcia-Manero, Guillermo, Abdel-Wahab, Noha, Tawbi, Hussein A., Hwu, Patrick, Oliva, Isabella C. Glitza, Davies, Michael A., Patel, Sapna P., Zou, Jun, Futreal, Andrew, Diab, Adi, Wang, Linghua, Nurieva, Roza

Volltext

A decision support framework for genomically informed investigational cancer therapy von Meric-Bernstam, Funda, Johnson, Amber, Holla, Vijaykumar, Bailey, Ann Marie, Brusco, Lauren, Chen, Ken, Routbort, Mark, Patel, Keyur P, Zeng, Jia, Kopetz, Scott, Davies, Michael A, Piha-Paul, Sarina A, Hong, David S, Eterovic, Agda Karina, Tsimberidou, Apostolia M, Broaddus, Russell, Bernstam, Elmer V, Shaw, Kenna R, Mendelsohn, John, Mills, Gordon B

Volltext