Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids von Kasendra, Magdalena, Tovaglieri, Alessio, Sontheimer-Phelps, Alexandra, Jalili-Firoozinezhad, Sasan, Bein, Amir, Chalkiadaki, Angeliki, Scholl, William, Zhang, Cheng, Rickner, Hannah, Richmond, Camilla A., Li, Hu, Breault, David T., Ingber, Donald E.

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Fully synthetic matrices for in vitro culture of primary human intestinal enteroids and endometrial organoids von Hernandez-Gordillo, Victor, Kassis, Timothy, Lampejo, Arinola, Choi, GiHun, Gamboa, Mario E., Gnecco, Juan S., Brown, Alexander, Breault, David T., Carrier, Rebecca, Griffith, Linda G.

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Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse von Stadtfeld, Matthias, Maherali, Nimet, Breault, David T, Hochedlinger, Konrad

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Frizzled proteins are colonic epithelial receptors for C. difficile toxin B von Tao, Liang, Zhang, Jie, Meraner, Paul, Tovaglieri, Alessio, Wu, Xiaoqian, Gerhard, Ralf, Zhang, Xinjun, Stallcup, William B., Miao, Ji, He, Xi, Hurdle, Julian G., Breault, David T., Brass, Abraham L., Dong, Min

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Intestinal enteroids recapitulate the effects of short-chain fatty acids on the intestinal epithelium von Pearce, Sarah C, Weber, Gregory J, van Sambeek, Dana M, Soares, Jason W, Racicot, Kenneth, Breault, David T

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Adrenocortical Zonation Results from Lineage Conversion of Differentiated Zona Glomerulosa Cells von Freedman, Bethany D., Kempna, Petra Bukovac, Carlone, Diana L., Shah, Manasvi S., Guagliardo, Nick A., Barrett, Paula Q., Gomez-Sanchez, Celso E., Majzoub, Joseph A., Breault, David T.

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A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip von Jalili-Firoozinezhad, Sasan, Gazzaniga, Francesca S., Calamari, Elizabeth L., Camacho, Diogo M., Fadel, Cicely W., Bein, Amir, Swenor, Ben, Nestor, Bret, Cronce, Michael J., Tovaglieri, Alessio, Levy, Oren, Gregory, Katherine E., Breault, David T., Cabral, Joaquim M. S., Kasper, Dennis L., Novak, Richard, Ingber, Donald E.

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Regulation of zonation and homeostasis in the adrenal cortex von Pignatti, Emanuele, Leng, Sining, Carlone, Diana L., Breault, David T.

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Reprogrammed Stomach Tissue as a Renewable Source of Functional β Cells for Blood Glucose Regulation von Ariyachet, Chaiyaboot, Tovaglieri, Alessio, Xiang, Guanjue, Lu, Jiaqi, Shah, Manasvi S., Richmond, Camilla A., Verbeke, Catia, Melton, Douglas A., Stanger, Ben Z., Mooney, David, Shivdasani, Ramesh A., Mahony, Shaun, Xia, Qing, Breault, David T., Zhou, Qiao

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Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells von Montgomery, Robert K, Carlone, Diana L, Richmond, Camilla A, Farilla, Loredana, Kranendonk, Mariette E.G, Henderson, Daniel E, Baffour-Awuah, Nana Yaa, Ambruzs, Dana M, Fogli, Laura K, Algra, Selma, Breault, David T

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Robust differentiation of human enteroendocrine cells from intestinal stem cells von Zeve, Daniel, Stas, Eric, de Sousa Casal, Joshua, Mannam, Prabhath, Qi, Wanshu, Yin, Xiaolei, Dubois, Sarah, Shah, Manasvi S., Syverson, Erin P., Hafner, Sophie, Karp, Jeffrey M., Carlone, Diana L., Ordovas-Montanes, Jose, Breault, David T.

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β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis von Leng, Sining, Pignatti, Emanuele, Khetani, Radhika S., Shah, Manasvi S., Xu, Simiao, Miao, Ji, Taketo, Makoto M., Beuschlein, Felix, Barrett, Paula Q., Carlone, Diana L., Breault, David T.

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Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites von Tovaglieri, Alessio, Sontheimer-Phelps, Alexandra, Geirnaert, Annelies, Prantil-Baun, Rachelle, Camacho, Diogo M, Chou, David B, Jalili-Firoozinezhad, Sasan, de Wouters, Tomás, Kasendra, Magdalena, Super, Michael, Cartwright, Mark J, Richmond, Camilla A, Breault, David T, Lacroix, Christophe, Ingber, Donald E

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Identification of TFPI as a receptor reveals recombination-driven receptor switching in Clostridioides difficile toxin B variants von Tian, Songhai, Xiong, Xiaozhe, Zeng, Ji, Wang, Siyu, Tremblay, Benjamin Jean-Marie, Chen, Peng, Chen, Baohua, Liu, Min, Chen, Pengsheng, Sheng, Kuanwei, Zeve, Daniel, Qi, Wanshu, Breault, David T., Rodríguez, César, Gerhard, Ralf, Jin, Rongsheng, Doxey, Andrew C., Dong, Min

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A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine von Sebastian, Carlos, Ferrer, Christina, Serra, Maria, Choi, Jee-Eun, Ducano, Nadia, Mira, Alessia, Shah, Manasvi S., Stopka, Sylwia A., Perciaccante, Andrew J., Isella, Claudio, Moya-Rull, Daniel, Vara-Messler, Marianela, Giordano, Silvia, Maldi, Elena, Desai, Niyati, Capen, Diane E., Medico, Enzo, Cetinbas, Murat, Sadreyev, Ruslan I., Brown, Dennis, Rivera, Miguel N., Sapino, Anna, Breault, David T., Agar, Nathalie Y. R., Mostoslavsky, Raul

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Dormant Intestinal Stem Cells Are Regulated by PTEN and Nutritional Status von Richmond, Camilla A., Shah, Manasvi S., Deary, Luke T., Trotier, Danny C., Thomas, Horatio, Ambruzs, Dana M., Jiang, Lijie, Whiles, Bristol B., Rickner, Hannah D., Montgomery, Robert K., Tovaglieri, Alessio, Carlone, Diana L., Breault, David T.

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Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation von Pignatti, Emanuele, Leng, Sining, Yuchi, Yixing, Borges, Kleiton S., Guagliardo, Nick A., Shah, Manasvi S., Ruiz-Babot, Gerard, Kariyawasam, Dulanjalee, Taketo, Makoto Mark, Miao, Ji, Barrett, Paula Q., Carlone, Diana L., Breault, David T.

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The Circadian Clock Gene BMAL1 Coordinates Intestinal Regeneration von Stokes, Kyle, Cooke, Abrial, Chang, Hanna, Weaver, David R, Breault, David T, Karpowicz, Phillip

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The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile von Lyons, Jesse, Ghazi, Phaedra C, Starchenko, Alina, Tovaglieri, Alessio, Baldwin, Katherine R, Poulin, Emily J, Gierut, Jessica J, Genetti, Casie, Yajnik, Vijay, Breault, David T, Lauffenburger, Douglas A, Haigis, Kevin M

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Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation in mice von Dufour, Damien, Dumontet, Typhanie, Sahut-Barnola, Isabelle, Carusi, Aude, Onzon, Méline, Pussard, Eric, Wilmouth, James Jr, Olabe, Julie, Lucas, Cécily, Levasseur, Adrien, Damon-Soubeyrand, Christelle, Pointud, Jean-Christophe, Roucher-Boulez, Florence, Tauveron, Igor, Bossis, Guillaume, Yeh, Edward T., Breault, David T., Val, Pierre, Lefrançois-Martinez, Anne-Marie, Martinez, Antoine

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