PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-Induced Cell Death von Gandhi, Sonia, Wood-Kaczmar, Alison, Yao, Zhi, Plun-Favreau, Helene, Deas, Emma, Klupsch, Kristina, Downward, Julian, Latchman, David S., Tabrizi, Sarah J., Wood, Nicholas W., Duchen, Michael R., Abramov, Andrey Y.

Volltext

Heat shock proteins and cardiac protection von LATCHMAN, David S

Volltext

STAT1 interacts directly with cyclin D1/Cdk4 and mediates cell cycle arrest von Dimco, Gloria, Knight, Richard A., Latchman, David S., Stephanou, Anastasis

Volltext

Transcriptional Modulation of Heat-Shock Protein Gene Expression von Stephanou, Anastasis, Latchman, David S.

Volltext

Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury von Valentim, Lauren, Laurence, Kevin M., Townsend, Paul A., Carroll, Christopher J., Soond, Surinder, Scarabelli, Tiziano M., Knight, Richard A., Latchman, David S., Stephanou, Anastasis

Volltext

Role of the JAK–STAT pathway in myocardial injury von Barry, Seán P, Townsend, Paul A, Latchman, David S, Stephanou, Anastasis

Volltext

Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β2-glycoprotein I in a mouse model of anti-phospholipid antibody-... von Pericleous, Charis, Ruiz-Limón, Patricia, Romay-Penabad, Zurina, Marín, Ana Carrera, Garza-Garcia, Acely, Murfitt, Lucy, Driscoll, Paul C, Latchman, David S, Isenberg, David A, Giles, Ian, Ioannou, Yiannis, Rahman, Anisur, Pierangeli, Silvia S

Volltext

Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1 von Valente, Enza Maria, Abou-Sleiman, Patrick M., Caputo, Viviana, Miratul M. K. Muqit, Harvey, Kirsten, Gispert, Suzana, Ali, Zeeshan, Del Turco, Domenico, Bentivoglio, Anna Rita, Healy, Daniel G., Albanese, Alberto, Nussbaum, Robert, González-Maldonado, Rafael, Deller, Thomas, Salvi, Sergio, Cortelli, Pietro, Gilks, William P., Latchman, David S., Harvey, Robert J., Dallapiccola, Bruno, Auburger, Georg, Wood, Nicholas W.

Volltext

Voltage-Gated Sodium Channel Expression and Potentiation of Human Breast Cancer Metastasis von FRASER, Scott P, DISS, James K. J, BRACKENBURY, William J, THEODOROU, Dimis, KOYUTURK, Meral, KAYA, Handan, BATTALOGLU, Esra, DE BELLA, Manuela Tamburo, SLADE, Martin J, TOLHURST, Robert, PALMIERI, Carlo, JIE JIANG, CHIONI, Athina-Myrto, LATCHMAN, David S, COOMBES, R. Charles, DJAMGOZ, Mustafa B. A, MYCIELSKA, Maria E, HUIYAN PAN, YAMACI, Rezan F, PANI, Filippo, BIWY, Zuzanna, KRASOWSKA, Monika, GRZYWNA, Zbigniew

Volltext

STAT-1 Interacts with p53 to Enhance DNA Damage-induced Apoptosis von Townsend, Paul A., Scarabelli, Tiziano M., Davidson, Sean M., Knight, Richard A., Latchman, David S., Stephanou, Anastasis

Volltext

PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons von Wood-Kaczmar, Alison, Gandhi, Sonia, Yao, Zhi, Abramov, Andrey Y, Abramov, Andrey S Y, Miljan, Erik A, Keen, Gregory, Stanyer, Lee, Hargreaves, Iain, Klupsch, Kristina, Deas, Emma, Downward, Julian, Mansfield, Louise, Jat, Parmjit, Taylor, Joanne, Heales, Simon, Duchen, Michael R, Latchman, David, Tabrizi, Sarah J, Wood, Nicholas W

Volltext

Nurr1 transcriptionally regulates the expression of α-synuclein von Yang, Yan Xiang, Latchman, David S

Volltext

Molecular basis of Parkinsonʼs disease von Yang, Yan Xiang, Wood, Nicholas W, Latchman, David S

Volltext

Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression von Sharp, Paul S, Akbar, Mohammed T, Bouri, Sonia, Senda, Atsushi, Joshi, Kieran, Chen, Han-Jou, Latchman, David S, Wells, Dominic J, de Belleroche, Jacqueline

Volltext

Epigallocatechin‐3‐gallate inhibits STAT‐1 activation and protects cardiac myocytes from ischemia/reperfusion‐ induced apoptosis von Townsend, Paul A., Scarabelli, Tiziano M., Pasini, Evasio, Gitti, Gianluca, Menegazzi, Marta, Suzuki, Hisanori, Knight, Richard A., Latchman, David S., Stephanou, Anastasis

Volltext

A heterozygous effect for PINK1 mutations in Parkinson's disease? von Abou-Sleiman, Patrick M., Muqit, Miratul M. K., McDonald, Neil Q., Yang, Yan Xiang, Gandhi, Sonia, Healy, Daniel G., Harvey, Kirsten, Harvey, Robert J., Deas, Emma, Bhatia, Kailash, Quinn, Niall, Lees, Andrew, Latchman, David S., Wood, Nicholas W.

Volltext

STAT3 modulates the DNA damage response pathway von Barry, Seán P., Townsend, Paul A., Knight, Richard A., Scarabelli, Tiziano M., Latchman, David S., Stephanou, Anastasis

Volltext

The Transcriptional Co-activators CREB-binding Protein (CBP) and p300 Play a Critical Role in Cardiac Hypertrophy That Is Dependent on Their Histone Acetyltransferase Activity von Gusterson, Rosalind J, Jazrawi, Elen, Adcock, Ian M, Latchman, David S

Volltext

Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate von Hudson, Chantelle D., Morris, Peter J., Latchman, David S., Budhram-Mahadeo, Vishwanie S.

Volltext

ERK and the F-box protein β TRCP target STAT1 for degradation von Soond, Surinder M, Townsend, Paul A, Barry, Sean P, Knight, Richard A, Latchman, David S, Stephanou, Anastasis

Volltext