How were new medicines discovered? von Swinney, David C, Anthony, Jason

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Recent advances in phenotypic drug discovery [version 1; peer review: 2 approved] von Swinney, David C, Lee, Jonathan A

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Why medicines work von Swinney, David C.

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The value of translational biomarkers to phenotypic assays von Swinney, David C

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A study of the molecular mechanism of binding kinetics and long residence times of human CCR5 receptor small molecule allosteric ligands von Swinney, David C, Beavis, Paul, Chuang, Kai‐Ting, Zheng, Yue, Lee, Ina, Gee, Peter, Deval, Jerome, Rotstein, David M, Dioszegi, Marianna, Ravendran, Palani, Zhang, Jun, Sankuratri, Surya, Kondru, Rama, Vauquelin, Georges

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Transcriptomic analysis of the woodchuck model of chronic hepatitis B von Fletcher, Simon P., Chin, Daniel J., Ji, Yongmei, Iniguez, A. Leonardo, Taillon, Bruce, Swinney, David C., Ravindran, Palanikumar, Cheng, Donavan T., Bitter, Hans, Lopatin, Uri, Ma, Han, Klumpp, Klaus, Menne, Stephan

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Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B von Fletcher, Simon P, Chin, Daniel J, Gruenbaum, Lore, Bitter, Hans, Rasmussen, Erik, Ravindran, Palanikumar, Swinney, David C, Birzele, Fabian, Schmucki, Roland, Lorenz, Stefan H, Kopetzki, Erhard, Carter, Jade, Triyatni, Miriam, Thampi, Linta M, Yang, Junming, AlDeghaither, Dalal, Murreddu, Marta G, Murredu, Marta G, Cote, Paul, Menne, Stephan

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A Four-Point Screening Method for Assessing Molecular Mechanism of Action (MMOA) Identifies Tideglusib as a Time-Dependent Inhibitor of Trypanosoma brucei GSK3β von Swinney, Zachary T, Haubrich, Brad A, Xia, Shuangluo, Ramesha, Chakk, Gomez, Stephen R, Guyett, Paul, Mensa-Wilmot, Kojo, Swinney, David C

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Contrasting Roles of Mitogen-Activated Protein Kinases in Cellular Entry and Replication of Hepatitis C Virus: MKNK1 Facilitates Cell Entry von Kim, Seungtaek, Ishida, Hisashi, Yamane, Daisuke, Yi, MinKyung, Swinney, David C, Foung, Steven, Lemon, Stanley M

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Fluxes for Unraveling Complex Binding Mechanisms von Vauquelin, Georges, Maes, Dominique, Swinney, David C.

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Cigarette Smoke Synergistically Enhances Respiratory Mucin Induction by Proinflammatory Stimuli von Baginski, Tomasz K, Dabbagh, Karim, Satjawatcharaphong, Chiradath, Swinney, David C

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The Contribution of Mechanistic Understanding to Phenotypic Screening for First-in-Class Medicines von Swinney, David C.

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Development of a Bioluminescent High-Throughput Screening Assay for Nicotinamide Mononucleotide Adenylyltransferase (NMNAT) von Haubrich, Brad A., Ramesha, Chakk, Swinney, David C.

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Biochemical mechanisms of drug action: what does it take for success? von Swinney, David C

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Essential Role of the N-terminal Domain in the Regulation of RIG-I ATPase Activity von Gee, Peter, Chua, Pong Kian, Gevorkyan, Jirair, Klumpp, Klaus, Najera, Isabel, Swinney, David C., Deval, Jerome

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Radioligand binding to intact cells as a tool for extended drug screening in a representative physiological context von Vauquelin, Georges, Van Liefde, Isabelle, Swinney, David C.

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Correction: Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B von Fletcher, Simon P, Chin, Daniel J, Gruenbaum, Lore, Bitter, Hans, Rasmussen, Erik, Ravindran, Palanikumar, Swinney, David C, Birzele, Fabian, Schmucki, Roland, Lorenz, Stefan H, Kopetzki, Erhard, Carter, Jade, Triyatni, Miriam, Thampi, Linta M, Yang, Junming, AlDeghaither, Dalal, Murreddu, Marta G, Cote, Paul, Menne, Stephan

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Collaboration for rare disease drug discovery research von Litterman, Nadia K, Rhee, Michele, Swinney, David C, Ekins, Sean

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On the different experimental manifestations of two‐state ‘induced‐fit’ binding of drugs to their cellular targets von Vauquelin, Georges, Van Liefde, Isabelle, Swinney, David C

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Activation Mechanism and Steady State Kinetics of Bruton's Tyrosine Kinase von Dinh, Marie, Grunberger, Dorit, Ho, Hoangdung, Tsing, Stan Y., Shaw, David, Lee, Simon, Barnett, Jim, Hill, Ronald J., Swinney, David C., Bradshaw, J. Michael

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