Synthesis and Structure−Activity Relationships of Azamacrocyclic C-X-C Chemokine Receptor 4 Antagonists: Analogues Containing a Single Azamacrocyclic Ring are Potent Inhibitors of... von Bridger, Gary J, Skerlj, Renato T, Hernandez-Abad, Pedro E, Bogucki, David E, Wang, Zhongren, Zhou, Yuanxi, Nan, Susan, Boehringer, Eva M, Wilson, Trevor, Crawford, Jason, Metz, Markus, Hatse, Sigrid, Princen, Katrien, De Clercq, Erik, Schols, Dominique

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Regio- and stereoselective ring contraction of 1,2-dithianes to 1,2-dithiolanes von Mansour, Tarek S., Evans, Colleen A., Bogucki, David E., Chowdhury, Sultan

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NBI-921352, a first-in-class, NaV1.6 selective, sodium channel inhibitor that prevents seizures in Scn8a gain-of-function mice, and wild-type mice and rats von Johnson, JP, Focken, Thilo, Khakh, Kuldip, Tari, Parisa Karimi, Dube, Celine, Goodchild, Samuel J, Andrez, Jean-Christophe, Bankar, Girish, Bogucki, David, Burford, Kristen, Chang, Elaine, Chowdhury, Sultan, Dean, Richard, de Boer, Gina, Decker, Shannon, Dehnhardt, Christoph, Feng, Mandy, Gong, Wei, Grimwood, Michael, Hasan, Abid, Hussainkhel, Angela, Jia, Qi, Lee, Stephanie, Li, Jenny, Lin, Sophia, Lindgren, Andrea, Lofstrand, Verner, Mezeyova, Janette, Namdari, Rostam, Nelkenbrecher, Karen, Shuart, Noah Gregory, Sojo, Luis, Sun, Shaoyi, Taron, Matthew, Waldbrook, Matthew, Weeratunge, Diana, Wesolowski, Steven, Williams, Aaron, Wilson, Michael, Xie, Zhiwei, Yoo, Rhena, Young, Clint, Zenova, Alla, Zhang, Wei, Cutts, Alison J, Sherrington, Robin P, Pimstone, Simon N, Winquist, Raymond, Cohen, Charles J, Empfield, James R

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An Asymmetric Synthesis of (-)-Deoxypodophyllotoxin von Bogucki, David E, Charlton, James L

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Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models von Focken, Thilo, Liu, Shifeng, Chahal, Navjot, Dauphinais, Maxim, Grimwood, Michael E, Chowdhury, Sultan, Hemeon, Ivan, Bichler, Paul, Bogucki, David, Waldbrook, Matthew, Bankar, Girish, Sojo, Luis E, Young, Clint, Lin, Sophia, Shuart, Noah, Kwan, Rainbow, Pang, Jodie, Chang, Jae H, Safina, Brian S, Sutherlin, Daniel P, Johnson, J. P, Dehnhardt, Christoph M, Mansour, Tarek S, Oballa, Renata M, Cohen, Charles J, Robinette, C. Lee

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A non-enzymatic synthesis of (S)-(−)-rosmarinic acid and a study of a biomimetic route to (+)-rabdosiin von Bogucki, David E, Charlton, James L

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Design of Substituted Imidazolidinylpiperidinylbenzoic Acids as Chemokine Receptor 5 Antagonists: Potent Inhibitors of R5 HIV‑1 Replication von Skerlj, Renato, Bridger, Gary, Zhou, Yuanxi, Bourque, Elyse, McEachern, Ernest, Metz, Markus, Harwig, Curtis, Li, Tong-Shuang, Yang, Wen, Bogucki, David, Zhu, Yongbao, Langille, Jonathan, Veale, Duane, Ba, Tuya, Bey, Michael, Baird, Ian, Kaller, Alan, Krumpak, Maria, Leitch, David, Satori, Michael, Vocadlo, Krystyna, Guay, Danielle, Nan, Susan, Yee, Helen, Crawford, Jason, Chen, Gang, Wilson, Trevor, Carpenter, Bryon, Gauthier, David, MacFarland, Ron, Mosi, Renee, Bodart, Veronique, Wong, Rebecca, Fricker, Simon, Schols, Dominique

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Synthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication von Skerlj, Renato, Bridger, Gary, McEachern, Ernie, Harwig, Curtis, Smith, Chris, Wilson, Trevor, Veale, Duane, Yee, Helen, Crawford, Jason, Skupinska, Krystyna, Wauthy, Rossana, Yang, Wen, Zhu, Yongbao, Bogucki, David, Di Fluri, Maria, Langille, Jonathon, Huskens, Dana, De Clercq, Erik, Schols, Dominique

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NBI-921352, a first-in-class, Na V 1.6 selective, sodium channel inhibitor that prevents seizures in Scn8a gain-of-function mice, and wild-type mice and rats von Johnson, J P, Focken, Thilo, Khakh, Kuldip, Tari, Parisa Karimi, Dube, Celine, Goodchild, Samuel J, Andrez, Jean-Christophe, Bankar, Girish, Bogucki, David, Burford, Kristen, Chang, Elaine, Chowdhury, Sultan, Dean, Richard, de Boer, Gina, Decker, Shannon, Dehnhardt, Christoph, Feng, Mandy, Gong, Wei, Grimwood, Michael, Hasan, Abid, Hussainkhel, Angela, Jia, Qi, Lee, Stephanie, Li, Jenny, Lin, Sophia, Lindgren, Andrea, Lofstrand, Verner, Mezeyova, Janette, Namdari, Rostam, Nelkenbrecher, Karen, Shuart, Noah Gregory, Sojo, Luis, Sun, Shaoyi, Taron, Matthew, Waldbrook, Matthew, Weeratunge, Diana, Wesolowski, Steven, Williams, Aaron, Wilson, Michael, Xie, Zhiwei, Yoo, Rhena, Young, Clint, Zenova, Alla, Zhang, Wei, Cutts, Alison J, Sherrington, Robin P, Pimstone, Simon N, Winquist, Raymond, Cohen, Charles J, Empfield, James R

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HIV - 1 entry inhibition by small - molecule CCR5 antagonists: A combined molecular modeling and mutant study using a high - throughput assay von Labrecque, Jean, Metz, Markus, Lau, Gloria, Darkes, Marilyn C, Wong, Rebecca S.Y, Bogucki, David, Carpenter, Bryon, Chen, Gang, Li, Tongshuang, Nan, Susan, Schols, Dominique, Bridger, Gary J, Fricker, Simon P, Skerlj, Renato T

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Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of Na V 1.7 with Efficacy in Rodent Pain Models von Focken, Thilo, Liu, Shifeng, Chahal, Navjot, Dauphinais, Maxim, Grimwood, Michael E., Chowdhury, Sultan, Hemeon, Ivan, Bichler, Paul, Bogucki, David, Waldbrook, Matthew, Bankar, Girish, Sojo, Luis E., Young, Clint, Lin, Sophia, Shuart, Noah, Kwan, Rainbow, Pang, Jodie, Chang, Jae H., Safina, Brian S., Sutherlin, Daniel P., Johnson, J. P., Dehnhardt, Christoph M., Mansour, Tarek S., Oballa, Renata M., Cohen, Charles J., Robinette, C. Lee

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Design and synthesis of pyridin-2-yloxymethylpiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication von Skerlj, Renato, Bridger, Gary, Zhou, Yuanxi, Bourque, Elyse, Langille, Jonathan, Fluri, Maria Di, Bogucki, David, Yang, Wen, Li, Tongshuang, Wang, Letian, Nan, Susan, Baird, Ian, Metz, Markus, Darkes, Marilyn, Labrecque, Jean, Lau, Gloria, Fricker, Simon, Huskens, Dana, Schols, Dominique

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HIV-1 entry inhibition by small-molecule CCR5 antagonists: A combined molecular modeling and mutant study using a high-throughput assay von Labrecque, Jean, Metz, Markus, Lau, Gloria, Darkes, Marilyn C, Wong, Rebecca S.Y, Bogucki, David, Carpenter, Bryon, Chen, Gang, Nan, Susan, Schols, Dominique, Bridger, Gary J, Fricker, Simon P, Skerlj, Renato T

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Design and synthesis of pyridin-2-yloxymethylpiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication von Skerlj, Renato, Bridger, Gary, Zhou, Yuanxi, Bourque, Elyse, Langille, Jonathan, Fluri, Maria Di, Bogucki, David, Yang, Wen, Wang, Letian, Nan, Susan, Baird, Ian, Metz, Markus, Darkes, Marilyn, Labrecque, Jean, Lau, Gloria, Fricker, Simon, Huskens, Dana, Schols, Dominique

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Synthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication von Skerlj, Renato, Bridger, Gary, McEachern, Ernie, Harwig, Curtis, Smith, Chris, Wilson, Trevor, Veale, Duane, Yee, Helen, Crawford, Jason, Skupinska, Krystyna, Wauthy, Rossana, Yang, Wen, Zhu, Yongbao, Bogucki, David, Di Fluri, Maria, Langille, Jonathon, Huskens, Dana, De Clercq, Erik, Schols, Dominique

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Synthesis and structure-activity relationships of azamacrocyclic C-X-C chemokine receptor 4 antagonists: analogues containing a single azamacrocyclic ring are potent inhibitors of... von Bridger, Gary J, Skerlj, Renato T, Hernandez-Abad, Pedro E, Bogucki, David E, Wang, Zhongren, Zhou, Yuanxi, Nan, Susan, Boehringer, Eva M, Wilson, Trevor, Crawford, Jason, Metz, Markus, Hatse, Sigrid, Princen, Katrien, De Clercq, Erik, Schols, Dominique

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SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF von BOGUCKI, David Earl, RABEA, Safwat Mohamed, HU, Kaiji

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SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF von BOGUCKI, David Earl, RABEA, Safwat Mohamed, HU, Kaiji

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Facile Cyanomethylation of Bromopyridines by Nucleophilic Substitution with Lithioacetonitrile von Skerlj, Renato T., Bogucki, David, Bridger, Gary J.

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ENDOCANNABINOID SYSTEM-TARGETING PRODRUGS AND THERAPEUTIC USES THEREOF von KODEKALRA, Rakshit D, BOGUCKI, David Earl, RABEA, Safwat M, PANDEY, Nihar R, PATIL, Mahadev, NEVALAINEN, Tapio, RAUTIO, Jarkko

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