Implications of human genetic variation in CRISPR-based therapeutic genome editing von Scott, David A, Zhang, Feng

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Activity-Induced Convergence of APP and BACE-1 in Acidic Microdomains via an Endocytosis-Dependent Pathway von Das, Utpal, Scott, David A., Ganguly, Archan, Koo, Edward H., Tang, Yong, Roy, Subhojit

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Cas13d Is a Compact RNA-Targeting Type VI CRISPR Effector Positively Modulated by a WYL-Domain-Containing Accessory Protein von Yan, Winston X., Chong, Shaorong, Zhang, Huaibin, Makarova, Kira S., Koonin, Eugene V., Cheng, David R., Scott, David A.

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Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells von Shalem, Ophir, Sanjana, Neville E., Hartenian, Ella, Shi, Xi, Scott, David A., Mikkelsen, Tarjei S., Heckl, Dirk, Ebert, Benjamin L., Root, David E., Doench, John G., Zhang, Feng

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α-Synuclein Multimers Cluster Synaptic Vesicles and Attenuate Recycling von Wang, Lina, Das, Utpal, Scott, David A., Tang, Yong, McLean, Pamela J., Roy, Subhojit

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Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis von Chen, Sidi, Sanjana, Neville E., Zheng, Kaijie, Shalem, Ophir, Lee, Kyungheon, Shi, Xi, Scott, David A., Song, Jun, Pan, Jen Q., Weissleder, Ralph, Lee, Hakho, Zhang, Feng, Sharp, Phillip A.

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Prevalence of Dementia 7.5 Years after Coronary Artery Bypass Graft Surgery von Evered, Lisbeth A, Silbert, Brendan S, Scott, David A, Maruff, Paul, Ames, David

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Mechanistic Logic Underlying the Axonal Transport of Cytosolic Proteins von Scott, David A., Das, Utpal, Tang, Yong, Roy, Subhojit

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Postoperative Cognitive Dysfunction Is Independent of Type of Surgery and Anesthetic von Evered, Lisbeth, Scott, David A., Silbert, Brendan, Maruff, Paul

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DNA targeting specificity of RNA-guided Cas9 nucleases von Hsu, Patrick D, Scott, David A, Weinstein, Joshua A, Ran, F Ann, Konermann, Silvana, Agarwala, Vineeta, Li, Yinqing, Fine, Eli J, Wu, Xuebing, Shalem, Ophir, Cradick, Thomas J, Marraffini, Luciano A, Bao, Gang, Zhang, Feng

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Regulation of Glutamine Carrier Proteins by RNF5 Determines Breast Cancer Response to ER Stress-Inducing Chemotherapies von Jeon, Young Joo, Khelifa, Sihem, Ratnikov, Boris, Scott, David A., Feng, Yongmei, Parisi, Fabio, Ruller, Chelsea, Lau, Eric, Kim, Hyungsoo, Brill, Laurence M., Jiang, Tingting, Rimm, David L., Cardiff, Robert D., Mills, Gordon B., Smith, Jeffrey W., Osterman, Andrei L., Kluger, Yuval, Ronai, Ze’ev A.

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Optical control of mammalian endogenous transcription and epigenetic states von Konermann, Silvana, Brigham, Mark D., Trevino, Alexandro E., Hsu, Patrick D., Heidenreich, Matthias, Le Cong, Platt, Randall J., Scott, David A., Church, George M., Zhang, Feng

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CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus von Ramanan, Vyas, Shlomai, Amir, Cox, David B.T., Schwartz, Robert E., Michailidis, Eleftherios, Bhatta, Ankit, Scott, David A., Zhang, Feng, Rice, Charles M., Bhatia, Sangeeta N.

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Mannose Alters Gut Microbiome, Prevents Diet-Induced Obesity, and Improves Host Metabolism von Sharma, Vandana, Smolin, Jamie, Nayak, Jonamani, Ayala, Julio E., Scott, David A., Peterson, Scott N., Freeze, Hudson H.

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Cerebrospinal Fluid Biomarker for Alzheimer Disease Predicts Postoperative Cognitive Dysfunction von Evered, Lisbeth, Silbert, Brendan, Scott, David A, Ames, David, Maruff, Paul, Blennow, Kaj

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Network meta-analysis on the log-hazard scale, combining count and hazard ratio statistics accounting for multi-arm trials: a tutorial von Woods, Beth S, Hawkins, Neil, Scott, David A

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State of the clinical science of perioperative brain health: report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018 von Mahanna-Gabrielli, Elizabeth, Schenning, Katie J., Eriksson, Lars I., Browndyke, Jeffrey N., Wright, Clinton B., Evered, Lis, Scott, David A., Wang, Nae Yah, Brown, Charles H., Oh, Esther, Purdon, Patrick, Inouye, Sharon, Berger, Miles, Whittington, Robert A., Deiner, Stacie

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Conducting Indirect-Treatment-Comparison and Network-Meta-Analysis Studies: Report of the ISPOR Task Force on Indirect Treatment Comparisons Good Research Practices: Part 2 von Hoaglin, David C., PhD, Hawkins, Neil, PhD, Jansen, Jeroen P., PhD, Scott, David A., MA, Itzler, Robbin, PhD, Cappelleri, Joseph C., PhD, MPH, Boersma, Cornelis, PhD, MSc, Thompson, David, PhD, Larholt, Kay M., ScD, Diaz, Mireya, PhD, Barrett, Annabel

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Delineation of global, absolutely essential and conditionally essential pangenomes of Porphyromonas gingivalis von Stocke, Kendall, Lamont, Gwyneth, Tan, Jinlian, Scott, David A.

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Macropinocytosis in Cancer-Associated Fibroblasts Is Dependent on CaMKK2/ARHGEF2 Signaling and Functions to Support Tumor and Stromal Cell Fitness von Zhang, Yijuan, Recouvreux, M. Victoria, Jung, Michael, Galenkamp, Koen M. O., Li, Yunbo, Zagnitko, Olga, Scott, David A., Lowy, Andrew M., Commisso, Cosimo

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