Can N-3 polyunsaturated fatty acids be considered a potential adjuvant therapy for COVID-19-associated cardiovascular complications? von Darwesh, Ahmed M., Bassiouni, Wesam, Sosnowski, Deanna K., Seubert, John M.

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Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin von Philippaert, Koenraad, Kalyaanamoorthy, Subha, Fatehi, Mohammad, Long, Wentong, Soni, Shubham, Byrne, Nikole J., Barr, Amy, Singh, Jyoti, Wong, Jordan, Palechuk, Taylor, Schneider, Chloe, Darwesh, Ahmed M., Maayah, Zaid H., Seubert, John M., Barakat, Khaled, Dyck, Jason R.B., Light, Peter E.

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Cytochrome P450-derived eicosanoids and heart function von Jamieson, K Lockhart, Endo, Tomoko, Darwesh, Ahmed M, Samokhvalov, Victor, Seubert, John M

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Cardioprotective properties of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids von Kranrod, Joshua, Konkel, Anne, Valencia, Robert, Darwesh, Ahmed M., Fischer, Robert, Schunck, Wolf-Hagen, Seubert, John M.

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Empagliflozin Blunts Worsening Cardiac Dysfunction Associated With Reduced NLRP3 (Nucleotide-Binding Domain-Like Receptor Protein 3) Inflammasome Activation in Heart Failure von Byrne, Nikole J., Matsumura, Nobutoshi, Maayah, Zaid H., Ferdaoussi, Mourad, Takahara, Shingo, Darwesh, Ahmed M., Levasseur, Jody L., Jahng, James Won Suk, Vos, Dyonne, Parajuli, Nirmal, El-Kadi, Ayman O.S., Braam, Branko, Young, Martin E., Verma, Subodh, Light, Peter E., Sweeney, Gary, Seubert, John M., Dyck, Jason R.B.

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Insights into the cardioprotective properties of n-3 PUFAs against ischemic heart disease via modulation of the innate immune system von Darwesh, Ahmed M., Sosnowski, Deanna K., Lee, Tim YT, Keshavarz-Bahaghighat, Hedieh, Seubert, John M.

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Insulin directly stimulates mitochondrial glucose oxidation in the heart von Karwi, Qutuba G, Wagg, Cory S, Altamimi, Tariq R, Uddin, Golam M, Ho, Kim L, Darwesh, Ahmed M, Seubert, John M, Lopaschuk, Gary D

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Chronically Elevating Circulating Ketones Can Reduce Cardiac Inflammation and Blunt the Development of Heart Failure von Byrne, Nikole J., Soni, Shubham, Takahara, Shingo, Ferdaoussi, Mourad, Al Batran, Rami, Darwesh, Ahmed M., Levasseur, Jody L., Beker, Donna, Vos, Dyonne Y., Schmidt, Mya A., Alam, Abrar S., Maayah, Zaid H., Schertzer, Jonathan D., Seubert, John M., Ussher, John R., Dyck, Jason R.B.

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Cytosolic carnitine acetyltransferase as a source of cytosolic acetyl-CoA: a possible mechanism for regulation of cardiac energy metabolism von Altamimi, Tariq R, Thomas, Panakkezhum D, Darwesh, Ahmed M, Fillmore, Natasha, Mahmoud, Mohammad U, Zhang, Liyan, Gupta, Abhishek, Al Batran, Rami, Seubert, John M, Lopaschuk, Gary D

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Genetic Deletion or Pharmacological Inhibition of Soluble Epoxide Hydrolase Ameliorates Cardiac Ischemia/Reperfusion Injury by Attenuating NLRP3 Inflammasome Activation von Darwesh, Ahmed M, Keshavarz-Bahaghighat, Hedieh, Jamieson, K Lockhart, Seubert, John M

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Cardioprotective effect of 19,20-epoxydocosapentaenoic acid (19,20-EDP) in ischaemic injury involves direct activation of mitochondrial sirtuin 3 von Darwesh, Ahmed M, Fang, Liye, Altamimi, Tariq R, Jamieson, K Lockhart, Bassiouni, Wesam, Valencia, Robert, Huang, Andy, Wang, Faqi, Zhang, Hao, Ahmed, Marawan, Gopal, Keshav, Zhang, Yongneng, Michelakis, Evangelos D, Ussher, John R, Edin, Matthew L, Zeldin, Darryl C, Barakat, Khaled, Oudit, Gavin Y, Kassiri, Zamaneh, Lopaschuk, Gary D, Seubert, John M

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Cardioprotective Action of a Novel Synthetic 19,20-EDP Analog Is Sirt Dependent von Kranrod, Joshua W, Darwesh, Ahmed M, Bassiouni, Wesam, Huang, Andy, Fang, Liye, Korodimas, Jacob V, Adebesin, Adeniyi Michael, Munnuri, Sailu, Falck, John R, Seubert, John M

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Mitochondrial Dysfunction and Inflammaging in Heart Failure: Novel Roles of CYP-Derived Epoxylipids von Keshavarz-Bahaghighat, Hedieh, Darwesh, Ahmed M, Sosnowski, Deanna K, Seubert, John M

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Loss of muscle PDH induces lactic acidosis and adaptive anaplerotic compensation via pyruvate-alanine cycling and glutaminolysis von Gopal, Keshav, Abdualkader, Abdualrahman Mohammed, Li, Xiaobei, Greenwell, Amanda A., Karwi, Qutuba G., Altamimi, Tariq R., Saed, Christina, Uddin, Golam M., Darwesh, Ahmed M., Jamieson, K. Lockhart, Kim, Ryekjang, Eaton, Farah, Seubert, John M., Lopaschuk, Gary D., Ussher, John R., Al Batran, Rami

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Loss of PI3Kα Mediates Protection From Myocardial Ischemia-Reperfusion Injury Linked to Preserved Mitochondrial Function von Zhabyeyev, Pavel, McLean, Brent, Bassiouni, Wesam, Valencia, Robert, Paul, Manish, Darwesh, Ahmed M, Seubert, John M, Hazra, Saugata, Oudit, Gavin Y

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A Synthetic Epoxydocosapentaenoic Acid Analogue Ameliorates Cardiac Ischemia/Reperfusion Injury: The Involvement of the Sirtuin 3-NLRP3 Pathway von Darwesh, Ahmed M, Bassiouni, Wesam, Adebesin, Adeniyi Michael, Mohammad, Abdul Sattar, Falck, John R, Seubert, John M

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Age and Sex Differences in Hearts of Soluble Epoxide Hydrolase Null Mice von Jamieson, K Lockhart, Keshavarz-Bahaghighat, Hedieh, Darwesh, Ahmed M, Sosnowski, Deanna K, Seubert, John M

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Deficiency of Soluble Epoxide Hydrolase Protects Cardiac Function Impaired by LPS-Induced Acute Inflammation von Samokhvalov, Victor, Jamieson, K Lockhart, Darwesh, Ahmed M, Keshavarz-Bahaghighat, Hedieh, Lee, Tim Y T, Edin, Matthew, Lih, Fred, Zeldin, Darryl C, Seubert, John M

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Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury von Jamieson, K Lockhart, Darwesh, Ahmed M, Sosnowski, Deanna K, Zhang, Hao, Shah, Saumya, Zhabyeyev, Pavel, Yang, Jun, Hammock, Bruce D, Edin, Matthew L, Zeldin, Darryl C, Oudit, Gavin Y, Kassiri, Zamaneh, Seubert, John M

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Cardioprotective Mechanisms of Exenatide in Isoprenaline-induced Myocardial Infarction: Novel Effects on Myocardial α-Estrogen Receptor Expression and IGF-1/IGF-2 System von Darwesh, Ahmed M, El-Azab, Mona F, Abo-Gresha, Noha M, El-Sayed, Norhan M, Moustafa, Yasser M

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