Recurrent Gain-of-Function Mutation in PRKG1 Causes Thoracic Aortic Aneurysms and Acute Aortic Dissections von Guo, Dong-chuan, Regalado, Ellen, Casteel, Darren E., Santos-Cortez, Regie L., Gong, Limin, Kim, Jeong Joo, Dyack, Sarah, Horne, S. Gabrielle, Chang, Guijuan, Jondeau, Guillaume, Boileau, Catherine, Coselli, Joseph S., Li, Zhenyu, Leal, Suzanne M., Shendure, Jay, Rieder, Mark J., Bamshad, Michael J., Nickerson, Deborah A., Kim, Choel, Milewicz, Dianna M.

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Nongenomic thyroid hormone signaling occurs through a plasma membrane-localized receptor von Kalyanaraman, Hema, Schwappacher, Raphaela, Joshua, Jisha, Zhuang, Shunhui, Scott, Brian T, Klos, Matthew, Casteel, Darren E, Frangos, John A, Dillmann, Wolfgang, Boss, Gerry R, Pilz, Renate B

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Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate von Fridman, Alla, Saha, Arindam, Chan, Adriano, Casteel, Darren E, Pilz, Renate B, Boss, Gerry R

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Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog von Schwaerzer, Gerburg K., Kalyanaraman, Hema, Casteel, Darren E., Dalton, Nancy D., Gu, Yusu, Lee, Seunghoe, Zhuang, Shunhui, Wahwah, Nisreen, Schilling, Jan M., Patel, Hemal H., Zhang, Qian, Makino, Ayako, Milewicz, Dianna M., Peterson, Kirk L., Boss, Gerry R., Pilz, Renate B.

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Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I von Huang, Gilbert Y., Kim, Jeong Joo, Reger, Albert S., Lorenz, Robin, Moon, Eui-Whan, Zhao, Chi, Casteel, Darren E., Bertinetti, Daniela, VanSchouwen, Bryan, Selvaratnam, Rajeevan, Pflugrath, James W., Sankaran, Banumathi, Melacini, Giuseppe, Herberg, Friedrich W., Kim, Choel

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Correction to: Crystal structure of PKG Iβ holoenzyme reveals a trans‑inhibiting dimer assembly von Kim, Choel, Sharma, Rajesh, Casteel, Darren E

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Regulation of Gene Expression by Cyclic GMP von Pilz, Renate B, Casteel, Darren E

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cGMP-dependent protein kinase-2 regulates bone mass and prevents diabetic bone loss von Ramdani, Ghania, Schall, Nadine, Kalyanaraman, Hema, Wahwah, Nisreen, Moheize, Sahar, Lee, Jenna J, Sah, Robert L, Pfeifer, Alexander, Casteel, Darren E, Pilz, Renate B

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Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation von Kim, Jeong Joo, Lorenz, Robin, Arold, Stefan T., Reger, Albert S., Sankaran, Banumathi, Casteel, Darren E., Herberg, Friedrich W., Kim, Choel

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An auto-inhibited state of protein kinase G and implications for selective activation von Sharma, Rajesh, Kim, Jeong Joo, Qin, Liying, Henning, Philipp, Akimoto, Madoka, VanSchouwen, Bryan, Kaur, Gundeep, Sankaran, Banumathi, MacKenzie, Kevin R, Melacini, Giuseppe, Casteel, Darren E, Herberg, Friedrich W, Kim, Choel

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Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication von Osborne, Brent W., Wu, Jian, McFarland, Caitlin J., Nickl, Christian K., Sankaran, Banumathi, Casteel, Darren E., Woods, Virgil L., Kornev, Alexandr P., Taylor, Susan S., Dostmann, Wolfgang R.

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Letter by Casteel Regarding Article, “Blood Pressure-Lowering by the Antioxidant Resveratrol Is Counterintuitively Mediated by Oxidation of the cGMP-Dependent Protein Kinase” von Casteel, Darren E

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Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts von Rangaswami, Hema, Schwappacher, Raphaela, Marathe, Nisha, Zhuang, Shunhui, Casteel, Darren E, Haas, Bodo, Chen, Yong, Pfeifer, Alexander, Kato, Hisashi, Shattil, Sanford, Boss, Gerry R, Pilz, Renate B

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Co-crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding von Kim, Jeong Joo, Casteel, Darren E, Huang, Gilbert, Kwon, Taek Hun, Ren, Ronnie Kuo, Zwart, Peter, Headd, Jeffrey J, Brown, Nicholas Gene, Chow, Dar-Chone, Palzkill, Timothy, Kim, Choel

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Crystal Structure of the cGMP-dependent Protein Kinase II Leucine Zipper and Rab11b Protein Complex Reveals Molecular Details of G-kinase-specific Interactions von Reger, Albert S., Yang, Matthew P., Koide-Yoshida, Shizuyo, Guo, Elaine, Mehta, Shrenik, Yuasa, Keizo, Liu, Alan, Casteel, Darren E., Kim, Choel

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Phosphatase regulatory subunit MYPT2 knockout partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3 von Hu, Tingfei, Kalyanaraman, Hema, Pilz, Renate B., Casteel, Darren E.

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PKGIα is activated by metal-dependent oxidation in vitro but not in intact cells von Aminzai, Sahar, Hu, Tingfei, Pilz, Renate B., Casteel, Darren E.

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The activity of cGMP-dependent protein kinase Iα is not directly regulated by oxidation-induced disulfide formation at cysteine 43 von Kalyanaraman, Hema, Zhuang, Shunhui, Pilz, Renate B., Casteel, Darren E.

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A plasma membrane-associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells von Kalyanaraman, Hema, Casteel, Darren E, China, Shyamsundar Pal, Zhuang, Shunhui, Boss, Gerry R, Pilz, Renate B

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Protein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes von Kalyanaraman, Hema, Schwaerzer, Gerburg, Ramdani, Ghania, Castillo, Francine, Scott, Brian T, Dillmann, Wolfgang, Sah, Robert L, Casteel, Darren E, Pilz, Renate B

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