E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation von Yang, Wei-Lei, Wang, Jing, Chan, Chia-Hsin, Lee, Szu-Wei, Campos, Alejandro D, Lamothe, Betty, Hur, Lana, Grabiner, Brian C, Lin, Xin, Darnay, Bryant G, Lin, Hui-Kuan

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Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice von Zhou, Xin, Zhang, Zhaoping, Feng, Jian Q., Dusevich, Vladmir M., Sinha, Krishna, Zhang, Hua, Darnay, Bryant G., de Crombrugghe, Benoit, Olson, Eric N.

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The E3 Ubiquitin Ligase TRAF6 Intercedes in Starvation-Induced Skeletal Muscle Atrophy through Multiple Mechanisms von Paul, Pradyut K., Bhatnagar, Shephali, Mishra, Vivek, Srivastava, Sanjay, Darnay, Bryant G., Choi, Yongwon, Kumar, Ashok

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Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice von Paul, Pradyut K., Gupta, Sanjay K., Bhatnagar, Shephali, Panguluri, Siva K., Darnay, Bryant G., Choi, Yongwon, Kumar, Ashok

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TAK1 Is Essential for Osteoclast Differentiation and Is an Important Modulator of Cell Death by Apoptosis and Necroptosis von Lamothe, Betty, Lai, YunJu, Xie, Min, Schneider, Michael D., Darnay, Bryant G.

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Cthrc1 is a positive regulator of osteoblastic bone formation von Kimura, Hiroaki, Kwan, Kin Ming, Zhang, Zhaoping, Deng, Jian Min, Darnay, Bryant G, Behringer, Richard R, Nakamura, Takashi, de Crombrugghe, Benoit, Akiyama, Haruhiko

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Ubiquitin-specific protease 25 regulates TLR4-dependent innate immune responses through deubiquitination of the adaptor protein TRAF3 von Zhong, Bo, Liu, Xikui, Wang, Xiaohu, Liu, Xindong, Li, Hongxiu, Darnay, Bryant G, Lin, Xin, Sun, Shao-Cong, Dong, Chen

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Site-specific Lys-63-linked Tumor Necrosis Factor Receptor-associated Factor 6 Auto-ubiquitination Is a Critical Determinant of IκB Kinase Activation von Lamothe, Betty, Besse, Arnaud, Campos, Alejandro D., Webster, William K., Wu, Hao, Darnay, Bryant G.

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Structural Basis for the Lack of E2 Interaction in the RING Domain of TRAF2 von Yin, Qian, Lamothe, Betty, Darnay, Bryant G, Wu, Hao

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E2 interaction and dimerization in the crystal structure of TRAF6 von Yin, Qian, Lin, Su-Chang, Lamothe, Betty, Lu, Miao, Lo, Yu-Chih, Hura, Gregory, Zheng, Lixin, Rich, Rebecca L, Campos, Alejandro D, Myszka, David G, Lenardo, Michael J, Darnay, Bryant G, Wu, Hao

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The RING Domain and First Zinc Finger of TRAF6 Coordinate Signaling by Interleukin-1, Lipopolysaccharide, and RANKL von Lamothe, Betty, Campos, Alejandro D., Webster, William K., Gopinathan, Ambily, Hur, Lana, Darnay, Bryant G.

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Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice von Lamothe, Betty, Lai, Yunju, Hur, Lana, Orozco, Natalia Martin, Wang, Jing, Campos, Alejandro D, Xie, Min, Schneider, Michael D, Lockworth, Cynthia R, Jakacky, Jared, Tran, Diep, Ho, Michael, Dawud, Sity, Dong, Chen, Lin, Hui-Kuan, Hu, Peter, Estrov, Zeev, Bueso-Ramos, Carlos E, Darnay, Bryant G

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Association Between Imatinib-Resistant BCR-ABL Mutation-Negative Leukemia and Persistent Activation of LYN Kinase von Wu, Ji, Meng, Feng, Kong, Ling-Yuan, Peng, Zhenghong, Ying, Yunming, Bornmann, William G., Darnay, Bryant G., Lamothe, Betty, Sun, Hanshi, Talpaz, Moshe, Donato, Nicholas J.

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Hypoxia-induced SUMOylation of E3 ligase HAF determines specific activation of HIF2 in clear-cell renal cell carcinoma von Koh, Mei Yee, Nguyen, Vuvi, Lemos, Jr, Robert, Darnay, Bryant G, Kiriakova, Galina, Abdelmelek, Mena, Ho, Thai H, Karam, Jose, Monzon, Federico A, Jonasch, Eric, Powis, Garth

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TRAF6 and the Three C-Terminal Lysine Sites on IRF7 Are Required for Its Ubiquitination-Mediated Activation by the Tumor Necrosis Factor Receptor Family Member Latent Membrane Prot... von Ning, Shunbin, Campos, Alex D., Darnay, Bryant G., Bentz, Gretchen L., Pagano, Joseph S.

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Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) and TGFβ-activated Kinase 1 (TAK1) Play Essential Roles in the C-type Lectin Receptor Signaling in Response to Candida al... von Gorjestani, Sara, Darnay, Bryant G., Lin, Xin

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Critical Role of Monoubiquitination of Histone H2AX Protein in Histone H2AX Phosphorylation and DNA Damage Response von Wu, Ching-Yuan, Kang, Hong-Yo, Yang, Wei-Lei, Wu, Juan, Jeong, Yun Seong, Wang, Jing, Chan, Chia-Hsin, Lee, Szu-Wei, Zhang, Xian, Lamothe, Betty, Campos, Alejandro D., Darnay, Bryant G., Lin, Hui-Kuan

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Hypoxia-Associated Factor, a Novel E3-Ubiquitin Ligase, Binds and Ubiquitinates Hypoxia-Inducible Factor 1α, Leading to Its Oxygen-Independent Degradation von Koh, Mei Yee, Darnay, Bryant G., Powis, Garth

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TAK1-dependent Signaling Requires Functional Interaction with TAB2/TAB3 von Besse, Arnaud, Lamothe, Betty, Campos, Alejandro D., Webster, William K., Maddineni, Upendra, Lin, Su-Chang, Wu, Hao, Darnay, Bryant G.

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TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation von Lamothe, Betty, Webster, William K., Gopinathan, Ambily, Besse, Arnaud, Campos, Alejandro D., Darnay, Bryant G.

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