Topical Sirolimus to Treat Tuberous Sclerosis Complex (TSC) von Darling, Thomas N

Volltext

Alteration of skin properties with autologous dermal fibroblasts von Thangapazham, Rajesh L, Darling, Thomas N, Meyerle, Jon

Volltext

Safety and efficacy of low-dose sirolimus in the PIK3CA-related overgrowth spectrum von Parker, Victoria E. R., Keppler-Noreuil, Kim M., Faivre, Laurence, Luu, Maxime, Oden, Neal L., De Silva, Leena, Sapp, Julie C., Andrews, Katrina, Bardou, Marc, Chen, Kong Y., Darling, Thomas N., Gautier, Elodie, Goldspiel, Barry R., Hadj-Rabia, Smail, Harris, Julie, Kounidas, Georgios, Kumar, Parag, Lindhurst, Marjorie J., Loffroy, Romaric, Martin, Ludovic, Phan, Alice, Rother, Kristina I., Widemann, Brigitte C., Wolters, Pamela L., Coubes, Christine, Pinson, Lucile, Willems, Marjolaine, Vincent-Delorme, Catherine, Vabres, Pierre, Semple, Robert K., Biesecker, Leslie G.

Volltext

Updated International Tuberous Sclerosis Complex Diagnostic Criteria and Surveillance and Management Recommendations von Northrup, Hope, Aronow, Mary E., Bebin, E. Martina, Bissler, John, Darling, Thomas N., de Vries, Petrus J., Frost, Michael D., Gosnell, Elizabeth S., Gupta, Nishant, Jansen, Anna C., Jóźwiak, Sergiusz, Kingswood, J. Chris, Knilans, Timothy K., McCormack, Francis X., Pounders, Ashley, Roberds, Steven L., Rodriguez-Buritica, David F., Roth, Jonathan, Sampson, Julian R., Sparagana, Steven, Thiele, Elizabeth Anne, Weiner, Howard L., Wheless, James W., Towbin, Alexander J., Krueger, Darcy A., Annear, Nicholas M.P., Aronow, Mary E., Bebin, E. Martina, Bissler, John J., Budde, Klemens, Byars, Anna, Chugani, Harry, Cowen, Edward W., Crino, Peter B., Curatolo, Paolo, Darling, Thomas N., de Vries, Petrus, Dilling, Daniel F., Dunn, David W., Ekong, Rosmary, Ess, Kevin C., Franz, David N., Frost, Michael, Gosnell, Elizabeth, Guay-Woodford, Lisa, Gupta, Nishant, Haddad, Luciana, Halbert, Anne, Hebert, Adelaide A., Henske, Elizabeth P., Hook, Dena, Hulbert, John, Jansen, Anna, Johnson, Simon R., Jóźwiak, Sergiusz, King, Bryan, Knilans, Timothy K., Koenig, Mary Kay, Korf, Bruce, Krueger, Darcy A., McCormack, Francis X., Moss, Joel, Mowat, David, Mowrey, Kate, Nabbout, Rima, Nellist, Mark D., Northrup, Hope, O'Callaghan, Finbar, Patel, Uday, Pounders, Ashley, Roach, E. Steve, Roberds, Steven L., Rodriguez-Buritica, David, Romp, Robb, Roth, Jonathan, Rozenberg, Micaela, Ruoss, Stephen J., Sahin, Mustafa, Sampson, Julian, Samuels, Joshua A., Sauter, Matthias, Smith, Catherine A., Soltani, Keyomaurs, Sparagana, Steven, Srivastava, Shoba, Stuart, Clare, Teng, Joyce M.C., Thiele, Elizabeth A., Towbin, Alexander J., Trout, Andrew, van Eeghen, Agnies, Vanclooster, Stephanie, Wang, Henry Z., Wataya-Kaneda, Mari, Weiner, Howard L., Wheless, James W., Witman, Patricia, Wright, Tim, Wu, Joyce Y., Young, Lisa

Volltext

Conditional reprogramming and long-term expansion of normal and tumor cells from human biospecimens von Liu, Xuefeng, Krawczyk, Ewa, Suprynowicz, Frank A, Palechor-Ceron, Nancy, Yuan, Hang, Dakic, Aleksandra, Simic, Vera, Zheng, Yun-Ling, Sripadhan, Praathibha, Chen, Chen, Lu, Jie, Hou, Tung-Wei, Choudhury, Sujata, Kallakury, Bhaskar, Tang, Dean G, Darling, Thomas, Thangapazham, Rajesh, Timofeeva, Olga, Dritschilo, Anatoly, Randell, Scott H, Albanese, Christopher, Agarwal, Seema, Schlegel, Richard

Volltext

Ultrasensitive profiling of UV-induced mutations identifies thousands of subclinical facial tumors in tuberous sclerosis complex von Klonowska, Katarzyna, Grevelink, Joannes M, Giannikou, Krinio, Ogorek, Barbara A, Herbert, Zachary T, Thorner, Aaron R, Darling, Thomas N, Moss, Joel, Kwiatkowski, David J

Volltext

Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation von Cao, Juxiang, Tyburczy, Magdalena E, Moss, Joel, Darling, Thomas N, Widlund, Hans R, Kwiatkowski, David J

Volltext

Central centrifugal cicatricial alopecia: A common but under‐recognized and under‐treated disease finally comes of age von Sperling, Leonard C., Darling, Thomas N.

Volltext

Dermatologic and Dental Aspects of the 2012 International Tuberous Sclerosis Complex Consensus Statements von Teng, Joyce M. C, Cowen, Edward W, Wataya-Kaneda, Mari, Gosnell, Elizabeth S, Witman, Patricia M, Hebert, Adelaide A, Mlynarczyk, Greg, Soltani, Keyoumars, Darling, Thomas N

Volltext

Comprehensive genetic and phenotype analysis of 95 individuals with mosaic tuberous sclerosis complex von Klonowska, Katarzyna, Giannikou, Krinio, Grevelink, Joannes M., Boeszoermenyi, Barbara, Thorner, Aaron R., Herbert, Zachary T., Afrin, Antara, Treichel, Alison M., Hamieh, Lana, Kotulska, Katarzyna, Jozwiak, Sergiusz, Moss, Joel, Darling, Thomas N., Kwiatkowski, David J.

Volltext

Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion von Medvetz, Doug A, Khabibullin, Damir, Hariharan, Venkatesh, Ongusaha, Pat P, Goncharova, Elena A, Schlechter, Tanja, Darling, Thomas N, Hofmann, Ilse, Krymskaya, Vera P, Liao, James K, Huang, Hayden, Henske, Elizabeth P

Volltext

Pharmacodynamic Study of Miransertib in Individuals with Proteus Syndrome von Keppler-Noreuil, Kim M., Sapp, Julie C., Lindhurst, Marjorie J., Darling, Thomas N., Burton-Akright, Jasmine, Bagheri, Mohammadhadi, Dombi, Eva, Gruber, Ashlyn, Jarosinski, Paul F., Martin, Staci, Nathan, Neera, Paul, Scott M., Savage, Ronald E., Wolters, Pamela L., Schwartz, Brian, Widemann, Brigitte C., Biesecker, Leslie G.

Volltext

Improvement of tuberous sclerosis complex (TSC) skin tumors during long-term treatment with oral sirolimus von Nathan, Neera, BA, Wang, Ji-an, AS, Li, Shaowei, MD, PhD, Cowen, Edward W., MD, MHSc, Haughey, Mary, RN, Moss, Joel, MD, PhD, Darling, Thomas N., MD, PhD

Volltext

Long-Term Effects of Sirolimus on Human Skin TSC2-Null Fibroblast‒Like Cells von Cai, Xiong, Fan, Qingyuan, Kang, Gi Soo, Grolig, Kelsey, Shen, Xiaoyan, Billings, Eric M., Pacheco-Rodriguez, Gustavo, Darling, Thomas N., Moss, Joel

Volltext

Hair graying may occur early in life in tuberous sclerosis complex and is distinct from poliosis von Cartron, Alexander M., Treichel, Alison M., Pithadia, Deeti J., Moss, Joel, Darling, Thomas N.

Volltext

Fibrous cephalic plaques in tuberous sclerosis complex von Oyerinde, Oyetewa, Buccine, Danielle, Treichel, Alison, Hong, Claire, Lee, Chyi-Chia Richard, Moss, Joel, Darling, Thomas N.

Volltext

Microenvironment Regulators of Metastasis Favor Lymphangioleiomyomatosis Cell Growth and Disease Progression von Pacheco-Rodriguez, Gustavo, Steagall, Wendy K, Glasgow, Connie G, Onishi, Rieko, Stylianou, Mario, Kato, Jiro, Li, Shaowei, Samsel, Leigh, McCoy, J Philip, Darling, Thomas N, Moss, Joel

Volltext

Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA von Lindhurst, Marjorie J, Parker, Victoria E R, Payne, Felicity, Sapp, Julie C, Rudge, Simon, Harris, Julie, Witkowski, Alison M, Zhang, Qifeng, Groeneveld, Matthijs P, Scott, Carol E, Daly, Allan, Huson, Susan M, Tosi, Laura L, Cunningham, Michael L, Darling, Thomas N, Geer, Joseph, Gucev, Zoran, Sutton, V Reid, Tziotzios, Christos, Dixon, Adrian K, Helliwell, Timothy, O'Rahilly, Stephen, Savage, David B, Wakelam, Michael J O, Barroso, Inês, Biesecker, Leslie G, Semple, Robert K

Volltext

Effect of beta-agonists on LAM progression and treatment von Le, Kang, Steagall, Wendy K., Stylianou, Mario, Pacheco-Rodriguez, Gustavo, Darling, Thomas N., Vaughan, Martha, Moss, Joel

Volltext

Dissociated Human Dermal Papilla Cells Induce Hair Follicle Neogenesis in Grafted Dermal–Epidermal Composites von Thangapazham, Rajesh L., Klover, Peter, Wang, Ji-an, Zheng, Ying, Devine, Amanda, Li, Shaowei, Sperling, Leonard, Cotsarelis, George, Darling, Thomas N.

Volltext