SUMO pathway inhibition targets an aggressive pancreatic cancer subtype von Biederstädt, Alexander, Hassan, Zonera, Schneeweis, Christian, Schick, Markus, Schneider, Lara, Muckenhuber, Alexander, Hong, Yingfen, Siegers, Gerrit, Nilsson, Lisa, Wirth, Matthias, Dantes, Zahra, Steiger, Katja, Schunck, Kathrin, Langston, Steve, Lenhof, H-P, Coluccio, Andrea, Orben, Felix, Slawska, Jolanta, Scherger, Anna, Saur, Dieter, Müller, Stefan, Rad, Roland, Weichert, Wilko, Nilsson, Jonas, Reichert, Maximilian, Schneider, Günter, Keller, Ulrich

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233P Breast cancer organoids mimic disease heterogeneity, allow high-throughput drug screening and show correlation with clinical response von Dantes, Z., Manjunath, A., Ferreira, L., Slawska, J., Steiger, K., Pfarr, N., Bernlochner, K., Hefel, B., Huang, L., Jesinghaus, M., Rosell, R., Kiechle, M., Dantes, M., Lindner, K., Peschel, C., Weichert, W., Paepke, S.

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MA04.09 The MET Inhibitor Tepotinib Potentially Inhibits KRAS G12C and SHOC2 in KRAS G12C Non-Small Cell Lung Cancer (NSCLC) von Rosell, R., Jain, A., Codony-Servat, J., Shivamallu, C., Prasad Kollur, S., Prasad, A., Jantus-Lewintre, E., Ito, M., Cardona, A.F., Arrieta, O., Cao, P., Cai, X., Xing, B., Pedraz-Valdunciel, C., Dantes, Z., Sullivan, I., Aguilar, A., Molina-Vila, M.A., González-Cao, M.

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199P Suppression of mutant Kirsten-RAS (KRAS G12C) non-small cell lung cancer (NSCLC) resistance to KRAS G12C inhibitors by dual inhibition of hepatocyte growth factor receptor (ME... von Rosell, R., Gómez-Vázquez, J.L., Lewintre, E. Jantus, Ito, M., Cao, P., Cai, X., Xing, B., Fariñas, S. Calabuig, Cardona, A.F., Rodríguez, J.K., Jordán, M. Marco, Valdunciel, C. Pedraz, Molina-Vila, M.A., Codony-Servat, J., Dantes, Z., Aguilar, A., Sullivan, I.G., Horno, I. Moya, Cirera, L., Gonzalez-Cao, M.

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Arming T cells with C-X-C-motive receptor 6 enhances infiltration of pancreatic cancer patient-derived organoids von Ogonek, J., Lutz, J., Dantes, Z., Lesch, S., Stoiber, S., Schuebel, M., Voelkl, L., Ormanns, S., Reichert, M., Endres, S., Kobold, S.

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32P Observational study to compare in vitro sensitivity to therapy in patients-derived organoids (PDOs) with real life outcome: The ChemoSenPDO study von Garcias-Donas, J., Dantes, Z., Jiménez, B., Yagüe, M., Manjunath, A., Ferreira, L., Hefel, B., Slawska, J., Rodríguez-Moreno, J.F., Sevillano, E., Barquin, A., Dorta Suarez, M., Rodriguez Pascual, J., Millan, C., Lopez, I., Jimenez, L., Müller, A., Barba, M., Ruiz-Llorente, S., Navarro, P.

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Phosphoproteomics identifies PI3K inhibitor-selective adaptive responses in pancreatic cancer cell therapy and resistance: Mapping PI3K inhibitor-dependent phosphoproteome von Cintas, C, Douche, T, Dantes, Z, Mouton-Barbosa, Emmanuelle, Bousquet, Marie-Pierre, Cayron, C, Therville, N, Pont, F, Ramos-Delgado, F, Guyon, Camille, Garmy-Susini, Barbara, Cappello, P, Burlet-Schiltz, Odile, Hirsch, E, Gomez-Brouchet, Anne, Thibault, B, Reichert, M, Guillermet-Guibert, Julie

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Arming T cells with C-X-C-motive receptor 6 enables adoptive T cell therapy of pancreatic cancer von Lesch, S., Blumenberg, V., Stoiber, S., Ogonek, J., Cadilha, B., Dantes, Z., Rataj, F., Dorman, K., Lutz, J., Karches, C., Heise, C., Grassmann, S., Megens, R., Ruehland, S., Di Pilato, M., Pruessmann, J., Ormanns, S., Reischer, A., Duewell, P., Schnurr, M., Subklewe, M., Reichert, M., Mempel, T., Endres, S., Kobold, S.

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Clinical impact of nonselective beta-blockers on survival in patients with pancreatic cancer- revival of well known drugs? von Renz, B.W., Graf, S., Dantes, Z., Macchini, M., Vecchiarelli, S., Ricci, C., Wang, T.C., Casadei, R., Di Marco, M., Reichert, M., Kleespies, A., Werner, J.

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Clinical impact of nonselective beta-blockers on survival in patients with pancreatic cancer- revival of well known drugs? von Renz, B.W., Graf, S., Dantes, Z., Macchini, M., Vecchiarelli, S., Ricci, C., Wang, T.C., Casadei, R., Di Marco, M., Reichert, M., Kleespies, A., Werner, J.

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Clinical Characteristics and Treatment Outcomes of Patients with Isoniazid-Monoresistant Tuberculosis von Cattamanchi, Adithya, Dantes, Raymund B., Metcalfe, John Z., Jarlsberg, Leah G., Grinsdale, Jennifer, Kawamura, L. Masae, Osmond, Dennis, Hopewell, Philip C., Nahid, Payam

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Overdiagnosis of COPD in Subjects With Unobstructed Spirometry: A BOLD Analysis von Sator, Lea, Horner, Andreas, Studnicka, Michael, Lamprecht, Bernd, Kaiser, Bernhard, McBurnie, Mary Ann, Buist, A Sonia, Gnatiuc, Luisa, Mannino, David M, Janson, Christer, Bateman, Eric D, Burney, Peter

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A Randomized Trial Comparing Intravitreal Triamcinolone Acetonide and Focal/Grid Photocoagulation for Diabetic Macular Edema

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Cross-national comparisons of socioeconomic differences in the prevalence of leisure-time and occupational physical activity, and active commuting in six Asia-Pacific countries von Bauman, Adrian, Ma, Guansheng, Cuevas, Frances, Omar, Zainal, Waqanivalu, Temo, Phongsavan, Philayrath, Keke, Kieren, Bhushan, Anjana

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Burden of obstructive lung disease in a rural setting in the Philippines von IDOLOR, LUISITO F., DE GUIA, TERESITA S., FRANCISCO, NORBERTO A., ROA, CAMILO C., AYUYAO, FERNANDO G., TADY, CECIL Z., TAN, DANIEL T., BANAL-YANG, SYLVIA, BALANAG JR, VINCENT M., REYES, MARIA TERESITA N., DANTES, RENATO B.

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Association of Baseline Visual Acuity and Retinal Thickness With 1-Year Efficacy of Aflibercept, Bevacizumab, and Ranibizumab for Diabetic Macular Edema von Wells, John A, Glassman, Adam R, Jampol, Lee M, Aiello, Lloyd Paul, Antoszyk, Andrew N, Baker, Carl W, Bressler, Neil M, Browning, David J, Connor, Crystal G, Elman, Michael J, Ferris, Frederick L, Friedman, Scott M, Melia, Michele, Pieramici, Dante J, Sun, Jennifer K, Beck, Roy W

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COPD: Should Diagnosis Match Physiology? von Studnicka, Michael, Horner, Andreas, Buist, A. Sonia, Lamprecht, Bernd, Lu, Jiachun, Ran, Pixin, Zhou, Yumin, Kocabaş, Ali, Hanta, Ismail, Kuleci, Sedat, Umut, Sema, Unalan, Turgay, Studnicka, Michael, Dawes, Torkil, Sator, Lea, Bateman, Eric, Barnes, Edward, Hayes, Anton, Johannisen, Christine, Koopman, Mariana, Ludick, Ina, Ryck, Johanna, Storbeck, Janita, Jörundsdottir, Kristin, Gudmundsdottir, Lovisa, Gudmundsdottir, Sigrun, Gundmundsson, Gunnar, Nizankowska-Mogilnicka, Ewa, Harat, Rafal, Pajak, Andrzej, Skucha, Wojciech, Welte, Tobias, Bodemann, Isabelle, Schweda-Linow, Alexandra, Svendsen, Lene, Tan, Wan C., Mannino, David M., Cain, John, Dantes, Renato B., Amarillo, Lourdes, Berratio, Lakan U., Garcia, Gerard S., de Guia, Teresita S., Idolor, Luisito F., Naval, Sullian S., Reyes, Thessa, Sanchez, Ma. Flordeliza, Marks, Guy, Burney, Peter G.J., Amor, Caron, Potts, James, Bárbara, Cristina, Dias, Hermínia, Cardoso, João, Almeida, João, Matos, Maria João, Simão, Paula, Ferreira, Reis, Janson, Christer, Spetz-Nyström, Ulrike, Hägg, Gunilla, Lund, Gun-Marie, Jõgi, Rain, Laja, Hendrik, Zobel, Vappu, Koul, Parvaiz A., Malik, Sajjad, Hakim, Nissar A., Chowgule, Rohini, Raphael, Jonelle, Katkar, Sunil, Dhanawade, Rupesh, Ghurup, Umesh, Tabka, Zouhair, Daldoul, Hager, Boukheroufa, Zaki, Chouikha, Firas, Khalifa, Wahbi Belhaj, Roa, Camilo C., Ayuyao, Fernando G., Tan, Daniel T., Banal-Yang, Sylvia, Balanag, Vincent M., Reyes, Maria Teresita N., Dantes, Renato. B., Hirve, Siddhi, Chaidhary, Bharat, Tambe, Meera, Pingale, Savita, Umap, Archana, Devchakke, Sampada, Chaudhary, Sharda, Bondre, Suvarna, Walke, Savita, Sapkal, Anil, Argade, Rupali, Gaikwad, Vijay, Brashier, Bill, Erhabor, Gregory, Adewole, Olufemi

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Down-Regulation of Steroidogenic Response to Gonadotropins in Human and Rat Preovulatory Granulosa Cells Involves Mitogen-Activated Protein Kinase Activation and Modulation of DAX-... von Tajima, Kimihisa, Dantes, Ada, Yao, Zhong, Sorokina, Ksenia, Kotsuji, Fumikazu, Seger, Rony, Amsterdam, Abraham

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Overdiagnosis of COPD in Subjects With Unobstructed Spirometry von Sator, Lea, Horner, Andreas, Studnicka, Michael, Lamprecht, Bernd, Kaiser, Bernhard, Mannino, David M., Liu, Shengming, Lu, Jiachun, Wang, Dali, Zheng, Jingping, Kocabaş, Ali, Hancioglu, Attila, Turkyilmaz, Ahmet Sinan, Adams, Desiree, Barnes, Edward, Freeman, Jasper, Hlengwa, Sipho, Louw, Innocentia, Olckers, Alta, Ryck, Johanna, Storbeck, Janita, Gislason, Thorarinn, Benedikdtsdottir, Bryndis, Gudmundsdottir, Lovisa, Nizankowska-Mogilnicka, Ewa, Frey, Jakub, Harat, Rafal, Mejza, Filip, Nastalek, Pawel, Szczeklik, Andrzej, Twardowska, Magda, Geldmacher, Henning, Gulsvik, Amund, Endresen, Tina, Svendsen, Lene, Tan, Wan C., Wang, Wen, Copeland, Rebecca, Hazen, Dana, Methvin, Jennifer, Dantes, Renato B., Fernandez, Lenora C., Francisco, Norberto A., Reyes, Thessa, Roa, Camilo C., Simpao, Leander P., Jenkins, Christine, Marks, Guy, Bird, Tessa, Espinel, Paola, Hardaker, Kate, Toelle, Brett, Tumilty, Michael, McLean, Fiona, Wouters, E.F.M., Wesseling, G.J., Rodrigues, Fátima, Dias, Hermínia, Cardoso, João, Almeida, João, Matos, Maria João, Simão, Paula, Santos, Moutinho, Olafsdottir, Inga Sif, Nisser, Katarina, Spetz-Nyström, Ulrike, Lund, Gun-Marie, Laja, Hendrik, Zobel, Vappu, Lill, Toomas-Julius, Koul, Parvaiz A., Malik, Sajjad, Khan, Umar Hafiz, Chowgule, Rohini, Shetye, Vasant, Almeda, Rosel, Tawde, Mahesh, Tadvi, Rafiq, Kadam, Milind, Harrabi, Imed, Daldoul, Hager, Boukheroufa, Zaki, Chouikha, Firas, Khalifa, Wahbi Belhaj, Idolor, Luisito F., Tady, Cecil Z., Banal-Yang, Sylvia, Juvekar, Sanjay, Sambhudas, Somnath, Tambe, Meera, Umap, Arati, Shelar, Nitin, Devchakke, Sampada, Argade, Rupali, Gaikwad, Vijay, Salvi, Sundeep, Brashier, Bill, Londhe, Jyoti, Obaseki, Daniel, Awopeju, Olayemi

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Optical Coherence Tomography Measurements and Analysis Methods in Optical Coherence Tomography Studies of Diabetic Macular Edema von Browning, David J., MD, PhD, Glassman, Adam R., MS, Aiello, Lloyd P., MD, PhD, Bressler, Neil M., MD, Bressler, Susan B., MD, Danis, Ronald P., MD, Davis, Matthew D., MD, Ferris, Frederick L., MD, Huang, Suber S., MD, Kaiser, Peter K., MD, Kollman, Craig, PhD, Sadda, Srinavas, MD, Scott, Ingrid U., MD, MPH, Qin, Haijing, MS

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