Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir von Tchesnokov, Egor P, Feng, Joy Y, Porter, Danielle P, Götte, Matthias

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The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus von Gordon, Calvin J., Tchesnokov, Egor P., Feng, Joy Y., Porter, Danielle P., Götte, Matthias

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Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency von Gordon, Calvin J., Tchesnokov, Egor P., Woolner, Emma, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias

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Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2 von Williamson, Brandi N., Feldmann, Friederike, Schwarz, Benjamin, Meade-White, Kimberly, Porter, Danielle P., Schulz, Jonathan, van Doremalen, Neeltje, Leighton, Ian, Yinda, Claude Kwe, Pérez-Pérez, Lizzette, Okumura, Atsushi, Lovaglio, Jamie, Hanley, Patrick W., Saturday, Greg, Bosio, Catharine M., Anzick, Sarah, Barbian, Kent, Cihlar, Tomas, Martens, Craig, Scott, Dana P., Munster, Vincent J., de Wit, Emmie

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Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action von Tchesnokov, Egor P., Gordon, Calvin J., Woolner, Emma, Kocinkova, Dana, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias

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KNDy Cells Revisited von Moore, Aleisha M, Coolen, Lique M, Porter, Danielle T, Goodman, Robert L, Lehman, Michael N

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Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV von Sheahan, Timothy P., Sims, Amy C., Leist, Sarah R., Schäfer, Alexandra, Won, John, Brown, Ariane J., Montgomery, Stephanie A., Hogg, Alison, Babusis, Darius, Clarke, Michael O., Spahn, Jamie E., Bauer, Laura, Sellers, Scott, Porter, Danielle, Feng, Joy Y., Cihlar, Tomas, Jordan, Robert, Denison, Mark R., Baric, Ralph S.

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Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor von Humeniuk, Rita, Mathias, Anita, Kirby, Brian J., Lutz, Justin D., Cao, Huyen, Osinusi, Anu, Babusis, Darius, Porter, Danielle, Wei, Xuelian, Ling, John, Reddy, Y. Sunila, German, Polina

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Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice von Pruijssers, Andrea J., George, Amelia S., Schäfer, Alexandra, Leist, Sarah R., Gralinksi, Lisa E., Dinnon, Kenneth H., Yount, Boyd L., Agostini, Maria L., Stevens, Laura J., Chappell, James D., Lu, Xiaotao, Hughes, Tia M., Gully, Kendra, Martinez, David R., Brown, Ariane J., Graham, Rachel L., Perry, Jason K., Du Pont, Venice, Pitts, Jared, Ma, Bin, Babusis, Darius, Murakami, Eisuke, Feng, Joy Y., Bilello, John P., Porter, Danielle P., Cihlar, Tomas, Baric, Ralph S., Denison, Mark R., Sheahan, Timothy P.

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Remdesivir efficacy against yellow fever in a hamster model von Julander, Justin G., Bunyan, Elaine, Jordan, Robert, Porter, Danielle P.

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“African Opinions” at the Brazzaville Conference: Evolué Politics, Representation, and the Future of French Colonialism in Africa von Sanchez, Danielle Porter

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Effect of remdesivir post-exposure prophylaxis and treatment on pathogenesis of measles in rhesus macaques von Peart Akindele, Nadine A., Katamoni, Laharika Dasharath, Brockhurst, Jacqueline, Ghimire, Shristi, Suwanmanee, San, Pieterse, Lisa, Metcalf Pate, Kelly A., Bunyan, Elaine, Bannister, Roy, Cihlar, Tomas, Porter, Danielle P., Griffin, Diane E.

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Localization of glutamatergic, GABAergic, and cholinergic neurons in the brain of the African cichlid fish, Astatotilapia burtoni von Maruska, Karen P., Butler, Julie M., Field, Karen E., Porter, Danielle T.

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Remdesivir and GS-441524 Retain Antiviral Activity against Delta, Omicron, and Other Emergent SARS-CoV-2 Variants von Pitts, Jared, Li, Jiani, Perry, Jason K, Du Pont, Venice, Riola, Nicholas, Rodriguez, Lauren, Lu, Xianghan, Kurhade, Chaitanya, Xie, Xuping, Camus, Gregory, Manhas, Savrina, Martin, Ross, Shi, Pei-Yong, Cihlar, Tomas, Porter, Danielle P, Mo, Hongmei, Maiorova, Evguenia, Bilello, John P

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A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial of Presatovir for the Treatment of Respiratory Syncytial Virus Upper Respiratory Tract Infection in Hematopoietic-Cell... von Chemaly, Roy F, Dadwal, Sanjeet S, Bergeron, Anne, Ljungman, Per, Kim, Yae-Jean, Cheng, Guang-Shing, Pipavath, Sudhakar N, Limaye, Ajit P, Blanchard, Elodie, Winston, Drew J, Stiff, Patrick J, Zuckerman, Tsila, Lachance, Silvy, Rahav, Galia, Small, Catherine B, Mullane, Kathleen M, Patron, Roberto L, Lee, Dong-Gun, Hirsch, Hans H, Waghmare, Alpana, McKevitt, Matt, Jordan, Robert, Guo, Ying, German, Polina, Porter, Danielle P, Gossage, David L, Watkins, Timothy R, Marty, Francisco M, Chien, Jason W, Boeckh, Michael

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Distribution and female reproductive state differences in orexigenic and anorexigenic neurons in the brain of the mouth brooding African cichlid fish, Astatotilapia burtoni von Porter, Danielle T., Roberts, David A., Maruska, Karen P.

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Prenatal Testosterone Exposure Alters GABAergic Synaptic Inputs to GnRH and KNDy Neurons in a Sheep Model of Polycystic Ovarian Syndrome von Porter, Danielle T, Moore, Aleisha M, Cobern, Jade A, Padmanabhan, Vasantha, Goodman, Robert L, Coolen, Lique M, Lehman, Michael N

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Combination therapy protects macaques against advanced Marburg virus disease von Cross, Robert W., Bornholdt, Zachary A., Prasad, Abhishek N., Borisevich, Viktoriya, Agans, Krystle N., Deer, Daniel J., Abelson, Dafna M., Kim, Do H., Shestowsky, William S., Campbell, Lioudmila A., Bunyan, Elaine, Geisbert, Joan B., Fenton, Karla A., Zeitlin, Larry, Porter, Danielle P., Geisbert, Thomas W.

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Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice von Martinez, David R., Schäfer, Alexandra, Leist, Sarah R., Li, Dapeng, Gully, Kendra, Yount, Boyd, Feng, Joy Y., Bunyan, Elaine, Porter, Danielle P., Cihlar, Tomas, Montgomery, Stephanie A., Haynes, Barton F., Baric, Ralph S., Nussenzweig, Michel C., Sheahan, Timothy P.

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Remdesivir (GS-5734) Is Efficacious in Cynomolgus Macaques Infected With Marburg Virus von Porter, Danielle P, Weidner, Jessica M, Gomba, Laura, Bannister, Roy, Blair, Christiana, Jordan, Robert, Wells, Jay, Wetzel, Kelly, Garza, Nicole, Van Tongeren, Sean, Donnelly, Ginger, Steffens, Jesse, Moreau, Alicia, Bearss, Jeremy, Lee, Eric, Bavari, Sina, Cihlar, Tomas, Warren, Travis K

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