Identification of structure–activity relationships for adverse effects of pharmaceuticals in humans: Part C: Use of QSAR and an expert system for the estimation of the mechanism of... von Matthews, Edwin J., Kruhlak, Naomi L., Daniel Benz, R., Sabaté, David Aragonés, Marchant, Carol A., Contrera, Joseph F.

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Predicting the carcinogenic potential of pharmaceuticals in rodents using molecular structural similarity and E-state indices von Contrera, Joseph F, Matthews, Edwin J, Daniel Benz, R

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Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations von Dearfield, Kerry L., Gollapudi, B. Bhaskar, Bemis, Jeffrey C., Benz, R. Daniel, Douglas, George R., Elespuru, Rosalie K., Johnson, George E., Kirkland, David J., LeBaron, Matthew J., Li, Albert P., Marchetti, Francesco, Pottenger, Lynn H., Rorije, Emiel, Tanir, Jennifer Y., Thybaud, Veronique, van Benthem, Jan, Yauk, Carole L., Zeiger, Errol, Luijten, Mirjam

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Combined Use of MC4PC, MDL-QSAR, BioEpisteme, Leadscope PDM, and Derek for Windows Software to Achieve High-Performance, High-Confidence, Mode of Action-Based Predictions of Chemic... von Matthews, Edwin J., Kruhlak, Naomi L., Benz, R. Daniel, Contrera, Joseph F., Marchant, Carol A., Yang, Chihae

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A comprehensive model for reproductive and developmental toxicity hazard identification: II. Construction of QSAR models to predict activities of untested chemicals von Matthews, Edwin J., Kruhlak, Naomi L., Daniel Benz, R., Ivanov, Julian, Klopman, Gilles, Contrera, Joseph F.

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Testing computational toxicology models with phytochemicals von Valerio, Luis G. Jr, Arvidson, Kirk B, Busta, Emily, Minnier, Barbara L, Kruhlak, Naomi L, Benz, R. Daniel

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A comprehensive model for reproductive and developmental toxicity hazard identification: I. Development of a weight of evidence QSAR database von Matthews, Edwin J., Kruhlak, Naomi L., Daniel Benz, R., Contrera, Joseph F.

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Genetic toxicology in the 21st century: Reflections and future directions von Mahadevan, Brinda, Snyder, Ronald D., Waters, Michael D., Benz, R.Daniel, Kemper, Raymond A., Tice, Raymond R., Richard, Ann M.

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Progress in QSAR toxicity screening of pharmaceutical impurities and other FDA regulated products von Kruhlak, Naomi L., Contrera, Joseph F., Benz, R. Daniel, Matthews, Edwin J.

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Toxicological and clinical computational analysis and the US FDA/CDER von Benz, R Daniel

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Identification of structure-activity relationships for adverse effects of pharmaceuticals in humans: Part B. Use of (Q)SAR systems for early detection of drug-induced hepatobiliary... von Matthews, Edwin J., Ursem, Carling J., Kruhlak, Naomi L., Benz, R. Daniel, Sabaté, David Aragonés, Yang, Chihae, Klopman, Gilles, Contrera, Joseph F.

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An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: I. Identification of carcinogens using surrogate endpoints von Matthews, Edwin J., Kruhlak, Naomi L., Cimino, Michael C., Benz, R. Daniel, Contrera, Joseph F.

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New and emerging technologies for genetic toxicity testing von Lynch, Anthony M, Sasaki, Jennifer C, Elespuru, Rosalie, Jacobson-Kram, David, Thybaud, Véronique, De Boeck, Marlies, Aardema, Marilyn J, Aubrecht, Jiri, Benz, R. Daniel, Dertinger, Stephen D, Douglas, George R, White, Paul A, Escobar, Patricia A, Fornace, Albert Jr, Honma, Masamitsu, Naven, Russell T, Rusling, James F, Schiestl, Robert H, Walmsley, Richard M, Yamamura, Eiji, van Benthem, Jan, Kim, James H

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An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: II. Identification of genotoxicants, reprotoxicants, and carcinogens using in si... von Matthews, Edwin J., Kruhlak, Naomi L., Cimino, Michael C., Benz, R. Daniel, Contrera, Joseph F.

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Comparison of MC4PC and MDL-QSAR rodent carcinogenicity predictions and the enhancement of predictive performance by combining QSAR models von Contrera, Joseph F., Kruhlak, Naomi L., Matthews, Edwin J., Benz, R. Daniel

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Identification of structure–activity relationships for adverse effects of pharmaceuticals in humans. Part A: Use of FDA post-market reports to create a database of hepatobiliary an... von Ursem, Carling J., Kruhlak, Naomi L., Contrera, Joseph F., MacLaughlin, Philip M., Benz, R. Daniel, Matthews, Edwin J.

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Estimating the safe starting dose in phase I clinical trials and no observed effect level based on QSAR modeling of the human maximum recommended daily dose von Contrera, Joseph F., Matthews, Edwin J., Kruhlak, Naomi L., Benz, R. Daniel

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In silico screening of chemicals for bacterial mutagenicity using electrotopological E-state indices and MDL QSAR software von Contrera, Joseph F., Matthews, Edwin J., Kruhlak, Naomi L., Benz, R. Daniel

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In Silico Screening of Chemicals for Genetic Toxicity Using MDL-QSAR, Nonparametric Discriminant Analysis, E-State, Connectivity, and Molecular Property Descriptors von Contrera, Joseph F., Matthews, Edwin J., Kruhlak, Naomi L., Benz, R. Daniel

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Progress in QSAR toxicity screening of pharmaceutical impurities and other FDA regulated products: Pharmaceutical impurities: Analytical, toxicological and regulatory perspectives von KRUHLAK, Naomi L, CONTRERA, Joseph F, BENZ, R. Daniel, MATTHEWS, Edwin J

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