CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels von Chini, Claudia C. S., Peclat, Thais R., Warner, Gina M., Kashyap, Sonu, Espindola-Netto, Jair Machado, de Oliveira, Guilherme C., Gomez, Lilian S., Hogan, Kelly A., Tarragó, Mariana G., Puranik, Amrutesh S., Agorrody, Guillermo, Thompson, Katie L., Dang, Kevin, Clarke, Starlynn, Childs, Bennett G., Kanamori, Karina S., Witte, Micaela A., Vidal, Paola, Kirkland, Anna L., De Cecco, Marco, Chellappa, Karthikeyani, McReynolds, Melanie R., Jankowski, Connor, Tchkonia, Tamara, Kirkland, James L., Sedivy, John M., van Deursen, Jan M., Baker, Darren J., van Schooten, Wim, Rabinowitz, Joshua D., Baur, Joseph A., Chini, Eduardo N.

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Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies von Clarke, Starlynn C, Ma, Biao, Trinklein, Nathan D, Schellenberger, Ute, Osborn, Michael J, Ouisse, Laure-Hélène, Boudreau, Andrew, Davison, Laura M, Harris, Katherine E, Ugamraj, Harshad S, Balasubramani, Aarti, Dang, Kevin H, Jorgensen, Brett, Ogana, Heather Anne N, Pham, Duy T, Pratap, Payal P, Sankaran, Preethi, Anegon, Ignacio, van Schooten, Wim C, Brüggemann, Marianne, Buelow, Roland, Force Aldred, Shelley

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Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies von Harris, Katherine E, Aldred, Shelley Force, Davison, Laura M, Ogana, Heather Anne N, Boudreau, Andrew, Brüggemann, Marianne, Osborn, Michael, Ma, Biao, Buelow, Benjamin, Clarke, Starlynn C, Dang, Kevin H, Iyer, Suhasini, Jorgensen, Brett, Pham, Duy T, Pratap, Payal P, Rangaswamy, Udaya S, Schellenberger, Ute, van Schooten, Wim C, Ugamraj, Harshad S, Vafa, Omid, Buelow, Roland, Trinklein, Nathan D

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Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release von Dang, Kevin, Castello, Giulia, Clarke, Starlynn C, Li, Yuping, Balasubramani, Aarti, Boudreau, Andrew, Davison, Laura, Harris, Katherine E, Pham, Duy, Sankaran, Preethi, Ugamraj, Harshad S, Deng, Rong, Kwek, Serena, Starzinski, Alec, Iyer, Suhasini, van Schooten, Wim, Schellenberger, Ute, Sun, Wenchao, Trinklein, Nathan D, Buelow, Roland, Buelow, Ben, Fong, Lawrence, Dalvi, Pranjali

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TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity von Ugamraj, Harshad S., Dang, Kevin, Ouisse, Laure-Hélène, Buelow, Benjamin, Chini, Eduardo N., Castello, Giulia, Allison, James, Clarke, Starlynn C, Davison, Laura M., Buelow, Roland, Deng, Rong, Iyer, Suhasini, Schellenberger, Ute, Manika, Sankar N., Bijpuria, Shipra, Musnier, Astrid, Poupon, Anne, Cuturi, Maria Cristina, van Schooten, Wim, Dalvi, Pranjali

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TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL von Malik-Chaudhry, Harbani K, Prabhakar, Kirthana, Ugamraj, Harshad S, Boudreau, Andrew A, Buelow, Benjamin, Dang, Kevin, Davison, Laura M, Harris, Katherine E, Jorgensen, Brett, Ogana, Heather, Pham, Duy, Schellenberger, Ute, Van Schooten, Wim, Buelow, Roland, Iyer, Suhasini, Trinklein, Nathan D, Rangaswamy, Udaya S

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Clinical Assessment of Eye Movement Desensitization and Reprocessing in Memory Distress: Protocol for a Double-Blinded Randomized Controlled Trial von Babaei, Nazanin, Kerry, Camrie, Goode, Kisha, Dang, Kevin, Mirzadeh, Parsa, Pirbaglou, Meysam, Kirk, Megan A, Ritvo, Paul

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A Web-Based Cognitive Behavioral Therapy, Mindfulness Meditation, and Yoga Intervention for Posttraumatic Stress Disorder: Single-Arm Experimental Clinical Trial von Kirk, Megan A, Taha, Bilal, Dang, Kevin, McCague, Hugh, Hatzinakos, Dimitrios, Katz, Joel, Ritvo, Paul

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The Use of Text Messaging as an Adjunct to Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder in Youth: Secondary Analysis von Walters, Clarice, Gratzer, David, Dang, Kevin, Laposa, Judith, Knyahnytska, Yuliya, Ortiz, Abigail, Gonzalez-Torres, Christina, Moore, Lindsay P, Chen, Sheng, Ma, Clement, Daskalakis, Zafiris, Ritvo, Paul

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The Role of Daily Steps in the Treatment of Major Depressive Disorder: Secondary Analysis of a Randomized Controlled Trial of a 6-Month Internet-Based, Mindfulness-Based Cognitive... von Dang, Kevin, Ritvo, Paul, Katz, Joel, Gratzer, David, Knyahnytska, Yuliya, Ortiz, Abigail, Walters, Clarice, Attia, Mohamed, Gonzalez-Torres, Christina, Lustig, Andrew, Daskalakis, Zafiris

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301 Preclinical development of AB-2100, a PSMA neovasculature-inducible CA9 CAR resistant to FASL and TGFb mediated suppression for the treatment of ccRCC von Scarfo, Irene, Lim, Laura, Dang, Kevin, Chew, Marvin, Sudhakah, Rakesh, Nguyen, Michelle, Mohanty, Suchismita, Chen, Jeremy, Gomez, Alma, Attanasio, Nickolas, Fearon, Amanda, Chan, Ivan, Sail, Vibhavari, Gardner, Thomas J, Millare, Beatriz, Zhang, James, Moskowitz, Darrian, Thomas, Vince, Zhou, Stanley, Smith, Jenessa, McDevitt, Jennifer, Boroughs, Angela

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Abstract TMP70: Association of Distal Hyperintense Vessel Sign and Outcomes in Patients With Symptomatic Posterior Circulation Intracranial Atherosclerotic Disease von Uppal, Hardeep, Saherwala, Ali, Dang, Kevin, Salahuddin, Hisham, Dang, Michael, Upadhyaya, Parth, Moore, William, Pinho, Marco, Shang, Ty T

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TAKAYASU ARTERITIS IN A YOUNG HISPANIC MALE von MORADI, ALI, SAUGSTAD, AUSTIN, DINNER, BRETT, DANG, KEVIN, MURALIDHARAN, ABILASH, QASIM AGHA, OSAMA, KHOKHAR, MATEEN

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Meaning in life and vagally-mediated heart rate variability: Evidence of a quadratic relationship at baseline and vagal reactivity differences von Dang, Kevin, Kirk, Megan A., Monette, Georges, Katz, Joel, Ritvo, Paul

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TNB585.001: A multicenter, phase 1, open-label, dose-escalation and expansion study of tnb-585, a bispecific T-cell engager targeting PSMA in subjects with metastatic castrate resi... von Buelow, Ben, Dalvi, Pranjali, Dang, Kevin, Patel, Ashwin, Johal, Kiran, Pham, Duy, Panchal, Shailee, Liu, Yvonne, Fong, Lawrence, Sartor, A. Oliver, McKean, Meredith, Schellenberger, Ute, Iyer, Suhasini

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Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies von Trinklein, Nathan D, Pham, Duy, Schellenberger, Ute, Buelow, Ben, Boudreau, Andrew, Choudhry, Priya, Clarke, Starlynn C, Dang, Kevin, Harris, Katherine E, Iyer, Suhasini, Jorgensen, Brett, Pratap, Payal P, Rangaswamy, Udaya S, Ugamraj, Harshad S, Vafa, Omid, Wiita, Arun P, van Schooten, Wim, Buelow, Roland, Force Aldred, Shelley

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Effect of modulation of CD3 binding in a PSMAxCD3 T-cell engaging bispecific antibody on maintenance of efficient tumor cell kill and cytokine release von Buelow, Ben, Dang, Kevin, Dalvi, Pranjali, Li, Yuping, Cheung, Alexander, Rancan, Chiara, Sankaran, Preethi, Pham, Duy, Harris, Katherine, Davison, Laura, Balasubramani, Aarti, Clarke, Starlynn, Starzinski, Alec, Fong, Lawrence, Iyer, Suhasini

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TNB-486, a Novel Fully Human Bispecific CD19 x CD3 Antibody That Kills CD19-Positive Tumor Cells with Minimal Cytokine Secretion von Malik, Harbani, Buelow, Ben, Rangaswamy, Udaya, Balasubramani, Aarti, Boudreau, Andrew, Dang, Kevin, Davison, Laura, Force Aldred, Shelley, Harris, Katherine Marie, Iyer, Suhasini, Jorgensen, Brett, Pham, Duy, Prabhakar, Kirthana, Schellenberger, Ute, Ugamraj, Harshad, Trinklein, Nathan, Van Schooten, Wim

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Evaluation of monovalent versus biparatopic CD3xPSMA bispecific antibodies for t-cell mediated killing of prostate tumor cells with minimal cytokine release von Buelow, Ben, Clarke, Starlynn, Dang, Kevin, Li, Jacky, Rancan, Chiara, Li, Yuping, Sankaran, Preethi, Pham, Duy, Balasubramani, Aarti, Davison, Laura, Harris, Katherine, Jorgensen, Brett, Schellenberger, Ute, Trinklein, Nathan, Ugamraj, Harshad, Fong, Lawrence, Van Schooten, Wim, Force Aldred, Shelley

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A novel CD3xPSMA bispecific antibody for efficient T cell mediated killing of prostate tumor cells with minimal cytokine release von Clarke, Starlynn, Dang, Kevin, Li, Yuping, Sankaran, Preethi, Pham, Duy, Balasubramani, Aarti, Davison, Laura, Harris, Katherine, Jorgensen, Brett, Schellenberger, Ute, Trinklein, Nathan, Ugamraj, Harshad, Buelow, Roland, Van Schooten, Wim, Force Aldred, Shelley, Buelow, Ben

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