Targeting Xist with compounds that disrupt RNA structure and X inactivation von Aguilar, Rodrigo, Spencer, Kerrie B., Kesner, Barry, Rizvi, Noreen F., Badmalia, Maulik D., Mrozowich, Tyler, Mortison, Jonathan D., Rivera, Carlos, Smith, Graham F., Burchard, Julja, Dandliker, Peter J., Patel, Trushar R., Nickbarg, Elliott B., Lee, Jeannie T.

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An orally available non-nucleotide STING agonist with antitumor activity von Pan, Bo-Sheng, Perera, Samanthi A., Piesvaux, Jennifer A., Presland, Jeremy P., Schroeder, Gottfried K., Cumming, Jared N., Trotter, B. Wesley, Altman, Michael D., Buevich, Alexei, Cash, Brandon, Cemerski, Saso, Chang, Wonsuk, Chen, Yiping, Dandliker, Peter J., Feng, Guo, Haidle, Andrew, Henderson, Timothy, Jewell, James, Kariv, Ilona, Knemeyer, Ian, Kopinja, Johnny, Lacey, Brian M., Laskey, Jason, Lesburg, Charles A., Liang, Rui, Long, Brian J., Lu, Min, Ma, Yanhong, Minnihan, Ellen C., O'Donnell, Greg, Otte, Ryan, Price, Laura, Rakhilina, Larissa, Sauvagnat, Berengere, Sharma, Sharad, Tyagarajan, Sriram, Woo, Hyun, Wyss, Daniel F., Xu, Serena, Bennett, David Jonathan, Addona, George H.

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Nanoscale synthesis and affinity ranking von Gesmundo, Nathan J., Sauvagnat, Bérengère, Curran, Patrick J., Richards, Matthew P., Andrews, Christine L., Dandliker, Peter J., Cernak, Tim

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Exploring new targets and chemical space with affinity selection-mass spectrometry von Prudent, Renaud, Annis, D. Allen, Dandliker, Peter J., Ortholand, Jean-Yves, Roche, Didier

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Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry von Rizvi, Noreen F, Howe, John A, Nahvi, Ali, Klein, Daniel J, Fischmann, Thierry O, Kim, Hai-Young, McCoy, Mark A, Walker, Scott S, Hruza, Alan, Richards, Matthew P, Chamberlin, Chad, Saradjian, Peter, Butko, Margaret T, Mercado, Gabriel, Burchard, Julja, Strickland, Corey, Dandliker, Peter J, Smith, Graham F, Nickbarg, Elliott B

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Macrocyclic α helical peptide therapeutic modality: A perspective of learnings and challenges von Sawyer, Tomi K., Partridge, Anthony W., Kaan, Hung Yi Kristal, Juang, Yu-Chi, Lim, Shuhui, Johannes, Charles, Yuen, Tsz Ying, Verma, Chandra, Kannan, Srinivasaraghavan, Aronica, Pietro, Tan, Yaw Sing, Sherborne, Brad, Ha, Sookhee, Hochman, Jerome, Chen, Shiying, Surdi, Laura, Peier, Andrea, Sauvagnat, Berengere, Dandliker, Peter J., Brown, Christopher J., Ng, Simon, Ferrer, Fernando, Lane, David P.

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Targeting RNA with Small Molecules: Identification of Selective, RNA-Binding Small Molecules Occupying Drug-Like Chemical Space von Rizvi, Noreen F., Santa Maria, John P., Nahvi, Ali, Klappenbach, Joel, Klein, Daniel J., Curran, Patrick J., Richards, Matthew P., Chamberlin, Chad, Saradjian, Peter, Burchard, Julja, Aguilar, Rodrigo, Lee, Jeannie T., Dandliker, Peter J., Smith, Graham F., Kutchukian, Peter, Nickbarg, Elliott B.

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Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor von Elwood, Fiona, Witter, David J, Piesvaux, Jennifer, Kraybill, Brian, Bays, Nathan, Alpert, Carla, Goldenblatt, Peter, Qu, Yujie, Ivanovska, Irena, Lee, Hyun-Hee, Chiu, Chi-Sung, Tang, Hao, Scott, Mark E, Deshmukh, Sujal V, Zielstorff, Mark, Byford, Alan, Chakravarthy, Kalyan, Dorosh, Lauren, Rivkin, Alexey, Klappenbach, Joel, Pan, Bo-Sheng, Kariv, Ilona, Dinsmore, Christopher, Slipetz, Deborah, Dandliker, Peter J

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Oxidative Thymine Dimer Repair in the DNA Helix von Dandliker, Peter J., Holmlin, R. Erik, Barton, Jacqueline K.

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Definitive Metabolite Identification Coupled with Automated Ligand Identification System (ALIS) Technology: A Novel Approach to Uncover Structure–Activity Relationships and Guide D... von Zhang, Ting, Liu, Yong, Yang, Xianshu, Martin, Gary E, Yao, Huifang, Shang, Jackie, Bugianesi, Randal M, Ellsworth, Kenneth P, Sonatore, Lisa M, Nizner, Peter, Sherer, Edward C, Hill, Susan E, Knemeyer, Ian W, Geissler, Wayne M, Dandliker, Peter J, Helmy, Roy, Wood, Harold B

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Integration of Affinity Selection–Mass Spectrometry and Functional Cell-Based Assays to Rapidly Triage Druggable Target Space within the NF-κB Pathway von Kutilek, Victoria D., Andrews, Christine L., Richards, Matthew P., Xu, Zangwei, Sun, Tianxiao, Chen, Yiping, Hashke, Andrew, Smotrov, Nadya, Fernandez, Rafael, Nickbarg, Elliott B., Chamberlin, Chad, Sauvagnat, Berengere, Curran, Patrick J., Boinay, Ryan, Saradjian, Peter, Allen, Samantha J., Byrne, Noel, Elsen, Nathaniel L., Ford, Rachael E., Hall, Dawn L., Kornienko, Maria, Rickert, Keith W., Sharma, Sujata, Shipman, Jennifer M., Lumb, Kevin J., Coleman, Kevin, Dandliker, Peter J., Kariv, Ilona, Beutel, Bruce

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SOS-NMR:  A Saturation Transfer NMR-Based Method for Determining the Structures of Protein−Ligand Complexes von Hajduk, Philip J, Mack, Jamey C, Olejniczak, Edward T, Park, Chang, Dandliker, Peter J, Beutel, Bruce A

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Pharmacokinetic Enhancement of the Hepatitis C Virus Protease Inhibitors VX-950 and SCH 503034 by Co-Dosing with Ritonavir von Kempf, Dale J, Klein, Cheri, Chen, Hui-Ju, Klein, Larry L, Yeung, Clinton, Randolph, John T, Lau, Yau Y, Chovan, Linda E, Guan, Zhiwen, Hernandez, Lisa, Turner, Teresa M, Dandliker, Peter J, Marsh, Kennan C

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Thienopyridine urea inhibitors of KDR kinase von Heyman, H. Robin, Frey, Robin R., Bousquet, Peter F., Cunha, George A., Moskey, Maria D., Ahmed, Asma A., Soni, Niru B., Marcotte, Patrick A., Pease, Lori J., Glaser, Keith B., Yates, Melinda, Bouska, Jennifer J., Albert, Daniel H., Black-Schaefer, Candace L., Dandliker, Peter J., Stewart, Kent D., Rafferty, Paul, Davidsen, Steven K., Michaelides, Michael R., Curtin, Michael L.

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Automatic mass spectrometry method development for drug discovery: application in metabolic stability assays von Chovan, Linda E., Black-Schaefer, Candace, Dandliker, Peter J., Lau, Yau Yi

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Oxidative Charge Transfer To Repair Thymine Dimers and Damage Guanine Bases in DNA Assemblies Containing Tethered Metallointercalators von Dandliker, Peter J, Núñez, Megan E, Barton, Jacqueline K

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Synthesis of Metallointercalator−DNA Conjugates on a Solid Support von Holmlin, R. Erik, Dandliker, Peter J, Barton, Jacqueline K

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Rapid hit to lead evaluation of pyrazolo[3,4- d]pyrimidin-4-one as selective and orally bioavailable mGluR1 antagonists von Wang, Xueqing, Kolasa, Teodozyi, El Kouhen, Odile F., Chovan, Linda E., Black-Shaefer, Candace L., Wagenaar, Frank L., Garton, Jennifer A., Moreland, Robert B., Honore, Prisca, Lau, Yau Yi, Dandliker, Peter J., Brioni, Jorge D., Stewart, Andrew O.

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Mechanism of Action of a Novel Series of Naphthyridine-Type Ribosome Inhibitors: Enhancement of tRNA Footprinting at the Decoding Site of 16S rRNA von Shen, Linus L, Black-Schaefer, Candace, Cai, Yingna, Dandliker, Peter J, Beutel, Bruce A

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Solid Phase Extraction as a Faster Alternative to HPLC: Application to MS Analysis of Metabolic Stability Samples von Inman, Brittany L., Chovan, Linda E., Dandliker, Peter J., Lau, Yau Yi

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