The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future von Mennen, Steven M, Alhambra, Carolina, Allen, C. Liana, Barberis, Mario, Berritt, Simon, Brandt, Thomas A, Campbell, Andrew D, Castañón, Jesús, Cherney, Alan H, Christensen, Melodie, Damon, David B, Eugenio de Diego, J, García-Cerrada, Susana, García-Losada, Pablo, Haro, Rubén, Janey, Jacob, Leitch, David C, Li, Ling, Liu, Fangfang, Lobben, Paul C, MacMillan, David W. C, Magano, Javier, McInturff, Emma, Monfette, Sebastien, Post, Ronald J, Schultz, Danielle, Sitter, Barbara J, Stevens, Jason M, Strambeanu, Iulia I, Twilton, Jack, Wang, Ke, Zajac, Matthew A

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Collaborative Evaluation of Commercially Available Automated Powder Dispensing Platforms for High-Throughput Experimentation in Pharmaceutical Applications von Bahr, Matthew N, Damon, David B, Yates, Simon D, Chin, Alexander S, Christopher, J. David, Cromer, Samuel, Perrotto, Nicholas, Quiroz, Jorge, Rosso, Victor

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Kinetic and Data-Driven Reaction Analysis for Pharmaceutical Process Development von Wang, Ke, Han, Lu, Mustakis, Jason, Li, Bryan, Magano, Javier, Damon, David B, Dion, Amelie, Maloney, Mark T, Post, Ronald, Li, Ruizhi

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Improvements to Enable the Large Scale Synthesis of 1‑{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833) von Wright, Stephen W, Li, Bryan, Peng, Zhihui, Wei, Lulin, McInturff, Emma, Place, David, Damon, David B, Singer, Robert A

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Asymmetric Synthesis of the Cholesteryl Ester Transfer Protein Inhibitor Torcetrapib von Damon, David B, Dugger, Robert W, Hubbs, Stephen E, Scott, Jill M, Scott, Robert W

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Synthesis of the CETP Inhibitor Torcetrapib:  The Resolution Route and Origin of Stereoselectivity in the Iminium Ion Cyclization von Damon, David B, Dugger, Robert W, Magnus-Aryitey, George, Ruggeri, Roger B, Wester, Ronald T, Tu, Meihua, Abramov, Yuriy

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Large-Scale Cyclopropanation of Butyl Acrylate with Difluorocarbene and Classical Resolution of a Key Fluorinated Building Block von Goetz, Adam E, Becirovic, Husein, Blasberg, Florian, Chen, Bo, Clarke, Hugh J, Colombo, Matteo, Daddario, Pedro, Damon, David B, Depretz, Christelle, Dumond, Yves R, Grilli, Maria D, Han, Lu, Houck, Tim L, Johnson, Amber M, Jones, Kris N, Jung, Jörg, Leeman, Michel, Liu, Fangfang, Lu, Cuong V, Mangual, Emilio J, Nelson, Jade D, Puchlopek-Dermenci, Angela L. A, Ruggeri, Sally Gut, Simonds, Paul A, Sitter, Barbara, Virtue, Daniel E, Wang, Shuguang, Yu, Lixin, Yu, Tao

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Process Development for the Synthesis of Monocyclic β‑Lactam Core 17 von Lall, Manjinder S, Tao, Yong, Arcari, Joel T, Boyles, David C, Brown, Matthew F, Damon, David B, Lilley, Susan C, Mitton-Fry, Mark J, Starr, Jeremy, Stewart, Andrew Morgan, Sun, Jianmin

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The Synthesis of Methyl-Substituted Spirocyclic Piperidine-Azetidine (2,7-Diazaspiro[3.5]nonane) and Spirocyclic Piperidine-Pyrrolidine (2,8-Diazaspiro[4.5]decane) Ring Systems von Smith, Aaron C, Cabral, Shawn, Kung, Daniel W, Rose, Colin R, Southers, James A, García-Irizarry, Carmen N, Damon, David B, Bagley, Scott W, Griffith, David A

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Kiloscale Buchwald–Hartwig Amination: Optimized Coupling of Base-Sensitive 6‑Bromoisoquinoline-1-carbonitrile with (S)‑3-Amino-2-methylpropan-1-ol von Sperry, Jeffrey B, Price Wiglesworth, Kristin E, Edmonds, Ian, Fiore, Phillip, Boyles, David C, Damon, David B, Dorow, Roberta L, Piatnitski Chekler, Eugene L, Langille, Jonathan, Coe, Jotham W

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Multikilogram Synthesis of a Hepatoselective Glucokinase Activator von Dunetz, Joshua R, Berliner, Martin A, Xiang, Yanqiao, Houck, Timothy L, Salingue, Fabrice H, Chao, Wang, Yuandong, Chen, Shenghua, Wang, Huang, Yun, Farrand, Douglas, Boucher, Steven J, Damon, David B, Makowski, Teresa W, Barrila, Mark T, Chen, Raymond, Martínez, Isamir

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Mesophase Formation in Regioregular Poly(3-alkylthiophene)s Containing Long Chain Alkyl Groups von Wang, Yu, Archambault, Nadia, Belcher, Allison M, Busse, Devin, Damon, David B, Mills, Ashley, Riddle, Amanda E, Samardjiev, Ivan J, Lucht, Brett L, Euler, William B

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Chemoselective Saponification in the Synthesis of Danuglipron Facilitated with Trifluoroethanol von Han, Lu, Li, Bryan, Wang, Ke, Damon, David B., Magano, Javier, Maloney, Mark T., Mustakis, Jason, Post, Ronald J., Li, Ruizhi, Nguyen, Truong

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Development of a Practical and Efficient Synthesis of CP-945,598-01, a CB1 Antagonist for the Treatment of Obesity von Ragan, John A, Bourassa, Dennis E, Blunt, Jon, Breen, Darragh, Busch, Frank R, Cordi, Eric M, Damon, David B, Do, Nga, Engtrakul, Alanya, Lynch, Denis, McDermott, Ruth E, Mongillo, Joseph A, O’Sullivan, Maria M, Rose, Peter R, Vanderplas, Brian C

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Synthesis of the ketodifluoromethylene dipeptide isostere von Damon, David B, Hoover, Dennis J

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Biarylcarboxylic Acids and -amides:  Inhibition of Phosphodiesterase Type IV versus [3H]Rolipram Binding Activity and Their Relationship to Emetic Behavior in the Ferret von Duplantier, Allen J, Biggers, Michael S, Chambers, Robert J, Cheng, John B, Cooper, Kelvin, Damon, David B, Eggler, James F, Kraus, Kenneth G, Marfat, Anthony, Masamune, Hiroko, Pillar, Joann S, Shirley, John T, Umland, John P, Watson, John W

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Development of two synthetic routes to CE-178,253, a CB1 antagonist for the treatment of obesity von Brandt, Thomas A., Caron, Stéphane, Damon, David B., DiBrino, Joseph, Ghosh, Arun, Griffith, David A., Kedia, Sandeep, Ragan, John A., Rose, Peter R., Vanderplas, Brian C., Wei, Lulin

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Synthesis and crystallographic analysis of two rhizopuspepsin inhibitor complexes von Parris, Kevin D, Hoover, Dennis J, Damon, David B, Davies, David R

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Development of two synthetic routes to CE-178,253, a CB1 antagonist for the treatment of obesity: Recent Advances in Synthetic Methodology: Development and Applications von BRANDT, Thomas A, CARON, Stéphane, LULIN WEI, DAMON, David B, DIBRINO, Joseph, GHOSH, Arun, GRIFFITH, David A, KEDIA, Sandeep, RAGAN, John A, ROSE, Peter R, VANDERPLAS, Brian C

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Development of a Practical and Efficient Synthesis of CP-945,598-01, a CB 1 Antagonist for the Treatment of Obesity von Ragan, John A., Bourassa, Dennis E., Blunt, Jon, Breen, Darragh, Busch, Frank R., Cordi, Eric M., Damon, David B., Do, Nga, Engtrakul, Alanya, Lynch, Denis, McDermott, Ruth E., Mongillo, Joseph A., O’Sullivan, Maria M., Rose, Peter R., Vanderplas, Brian C.

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