Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion von Hong, Sungguan, Zhou, Wenjun, Fang, Bin, Lu, Wenyun, Loro, Emanuele, Damle, Manashree, Ding, Guolian, Jager, Jennifer, Zhang, Sisi, Zhang, Yuxiang, Feng, Dan, Chu, Qingwei, Dill, Brian D, Molina, Henrik, Khurana, Tejvir S, Rabinowitz, Joshua D, Lazar, Mitchell A, Sun, Zheng

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An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides von Armour, Sean M., Remsberg, Jarrett R., Damle, Manashree, Sidoli, Simone, Ho, Wesley Y., Li, Zhenghui, Garcia, Benjamin A., Lazar, Mitchell A.

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Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP von Papazyan, Romeo, Sun, Zheng, Kim, Yong Hoon, Titchenell, Paul M., Hill, David A., Lu, Wenyun, Damle, Manashree, Wan, Min, Zhang, Yuxiang, Briggs, Erika R., Rabinowitz, Joshua D., Lazar, Mitchell A.

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Deletion of histone deacetylase 3 in adult beta cells improves glucose tolerance via increased insulin secretion von Remsberg, Jarrett R, Ediger, Benjamin N, Ho, Wesley Y, Damle, Manashree, Li, Zhenghui, Teng, Christopher, Lanzillotta, Cristina, Stoffers, Doris A, Lazar, Mitchell A

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Genetic backgrounds determine brown remodeling of white fat in rodents von Ferrannini, Giulia, Namwanje, Maria, Fang, Bin, Damle, Manashree, Li, Dylan, Liu, Qiongming, Lazar, Mitchell A, Qiang, Li

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Full methylation of H3K27 by PRC2 is dispensable for initial embryoid body formation but required to maintain differentiated cell identity von Miller, Sara A., Damle, Manashree, Kim, Jongmin, Kingston, Robert E.

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Identification of C2CD4A as a human diabetes susceptibility gene with a role in β cell insulin secretion von Kuo, Taiyi, Kraakman, Michael J., Damle, Manashree, Gill, Richard, Lazar, Mitchell A., Accili, Domenico

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Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock von Zhang, Yuxiang, Fang, Bin, Emmett, Matthew J., Damle, Manashree, Sun, Zheng, Feng, Dan, Armour, Sean M., Remsberg, Jarrett R., Jager, Jennifer, Soccio, Raymond E., Steger, David J., Lazar, Mitchell A.

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TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways von Tchasovnikarova, Iva A., Marr, Sharon K., Damle, Manashree, Kingston, Robert E.

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The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γ von Zhang, Yuxiang, Papazyan, Romeo, Damle, Manashree, Fang, Bin, Jager, Jennifer, Feng, Dan, Peed, Lindsey C, Guan, Dongyin, Sun, Zheng, Lazar, Mitchell A

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Elongin A associates with actively transcribed genes and modulates enhancer RNA levels with limited impact on transcription elongation rate in vivo von Ardehali, M. Behfar, Damle, Manashree, Perea-Resa, Carlos, Blower, Michael D., Kingston, Robert E.

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HNF6 and Rev-erbα integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanisms von Zhang, Yuxiang, Fang, Bin, Damle, Manashree, Guan, Dongyin, Li, Zhenghui, Kim, Yong Hoon, Gannon, Maureen, Lazar, Mitchell A

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A Polycomb domain found in committed cells impairs differentiation when introduced into PRC1 in pluripotent cells von Jaensch, Elizabeth S., Zhu, Jinjin, Cochrane, Jesse C., Marr, Sharon K., Oei, Theresa A., Damle, Manashree, McCaslin, Ethan Z., Kingston, Robert E.

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S-phase Enriched Non-coding RNAs Regulate Gene Expression and Cell Cycle Progression von Yildirim, Ozlem, Izgu, Enver C., Damle, Manashree, Chalei, Vladislava, Ji, Fei, Sadreyev, Ruslan I., Szostak, Jack W., Kingston, Robert E.

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Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice von Soccio, Raymond E, Li, Zhenghui, Chen, Eric R, Foong, Yee Hoon, Benson, Kiara K, Dispirito, Joanna R, Mullican, Shannon E, Emmett, Matthew J, Briggs, Erika R, Peed, Lindsey C, Dzeng, Richard K, Medina, Carlos J, Jolivert, Jennifer F, Kissig, Megan, Rajapurkar, Satyajit R, Damle, Manashree, Lim, Hee-Woong, Won, Kyoung-Jae, Seale, Patrick, Steger, David J, Lazar, Mitchell A

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Targeting PPAR[gamma] in the epigenome rescues genetic metabolic defects in mice von Soccio, Raymond E, Li, Zhenghui, Chen, Eric R, Foong, Yee Hoon, Benson, Kiara K, Dispirito, Joanna R, Mullican, Shannon E, Emmett, Matthew J, Briggs, Erika R, Peed, Lindsey C, Dzeng, Richard K, Medina, Carlos J, Jolivert, Jennifer F, Kissig, Megan, Rajapurkar, Satyajit R, Damle, Manashree, Lim, Hee-Woong, Won, Kyoung-Jae, Seale, Patrick, Steger, David J, Lazar, Mitchell A

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Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle von Gong, Yingyun, Cao, Rui, Ding, Guolian, Hong, Sungguan, Zhou, Wenjun, Lu, Wenyun, Damle, Manashree, Fang, Bin, Wang, Chuhan C., Qian, Justin, Lie, Natasha, Lanzillotta, Cristina, Rabinowitz, Joshua D., Sun, Zheng

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Induction of α cell-restricted Gc in dedifferentiating β cells contributes to stress-induced β-cell dysfunction von Kuo, Taiyi, Damle, Manashree, González, Bryan J, Egli, Dietrich, Lazar, Mitchell A, Accili, Domenico

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HERVH-derived lncRNAs negatively regulate chromatin targeting and remodeling mediated by CHD7 von Hsieh, Fu-Kai, Ji, Fei, Damle, Manashree, Sadreyev, Ruslan I, Kingston, Robert E

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Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 von Hong, Sungguan, Zhou, Wenjun, Fang, Bin, Lu, Wenyun, Loro, Emanuele, Damle, Manashree, Ding, Guolian, Jager, Jennifer, Zhang, Sisi, Zhang, Yuxiang, Feng, Dan, Chu, Qingwei, Dill, Brian D, Molina, Henrik, Khurana, Tejvir S, Rabinowitz, Joshua D, Lazar, Mitchell A, Sun, Zheng

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