One-pot synthesis of amino-alcohols using a de-novo transketolase and β-alanine: Pyruvate transaminase pathway in Escherichia coli von Ingram, C.U., Bommer, M., Smith, M.E.B., Dalby, P.A., Ward, J.M., Hailes, H.C., Lye, G.J.

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An open source in silico workflow to assist in the design of fusion proteins von Lalaurie, C.J., Zhang, C., Liu, S.M., Bunting, K.A., Dalby, P.A.

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Impact of cofactor-binding loop mutations on thermotolerance and activity of E. coli transketolase von Morris, P., Rios-Solis, L., García-Arrazola, R., Lye, G.J., Dalby, P.A.

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Modelling and optimisation of the one-pot, multi-enzymatic synthesis of chiral amino-alcohols based on microscale kinetic parameter determination von Rios-Solis, L., Morris, P., Grant, C., Odeleye, A.O.O., Hailes, H.C., Ward, J.M., Dalby, P.A., Baganz, F., Lye, G.J.

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Optimising enzyme function by directed evolution von Dalby, Paul A

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Accelerated design of bioconversion processes using automated microscale processing techniques von Lye, Gary J., Ayazi-Shamlou, Parviz, Baganz, Frank, Dalby, Paul A., Woodley, John M.

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Reaction modelling and simulation to assess the integrated use of transketolase and ω-transaminase for the synthesis of an aminotriol von Chen, B. H., Sayar, A., Kaulmann, U., Dalby, P. A., Ward, J. M., Woodley, J. M.

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Rolapitant for the Prevention of Postoperative Nausea and Vomiting: A Prospective, Double-Blinded, Placebo-Controlled Randomized Trial von Gan, Tong J., Gu, Jiezhun, Singla, Neil, Chung, Frances, Pearman, Michael H., Bergese, Sergio D., Habib, Ashraf S., Candiotti, Keith A., Mo, Yi, Huyck, Susan, Creed, Mary R., Cantillon, Marc

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Folding intermediates of wild-type and mutants of barnase. I. use of φ-value analysis and m-values to probe the cooperative nature of the folding pre-equilibrium von Dalby, Paul A., Oliveberg, Mikael, Fersht, Alan R.

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Directed evolution of transketolase substrate specificity towards an aliphatic aldehyde von Hibbert, Edward G., Senussi, Tarik, Smith, Mark E.B., Costelloe, Sean J., Ward, John M., Hailes, Helen C., Dalby, Paul A.

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Directed evolution of transketolase activity on non-phosphorylated substrates von Hibbert, Edward G., Senussi, Tarik, Costelloe, Sean J., Lei, Wenling, Smith, Mark E.B., Ward, John M., Hailes, Helen C., Dalby, Paul A.

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Movement of the Intermediate and Rate Determining Transition State of Barnase on the Energy Landscape with Changing Temperature von Dalby, Paul A, Oliveberg, Mikael, Fersht, Alan R

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Evolution of binding affinity in a WW domain probed by phage display von DALBY, PAUL A., HOESS, RONALD H., DeGRADO, WILLIAM F.

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Distributions of enzyme residues yielding mutants with improved substrate specificities from two different directed evolution strategies von Paramesvaran, Janahan, Hibbert, Edward G., Russell, Andrew J., Dalby, Paul A.

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Folding intermediates of wild-type and mutants of barnase. II. correlation of changes in equilibrium amide exchange kinetics with the population of the folding intermediate von Dalby, Paul A., Clarke, Jane, Johnson, Christopher M., Fersht, Alan R.

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Directed evolution strategies for improved enzymatic performance von Hibbert, Edward G, Dalby, Paul A

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High-throughput measurement of protein stability in microtiter plates von Aucamp, Jean P., Cosme, Ana M., Lye, Gary J., Dalby, Paul A.

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An integrated biorefinery concept for conversion of sugar beet pulp into value-added chemicals and pharmaceutical intermediates von Cardenas-Fernandez, M, Bawn, M, Hamley-Bennett, C, Bharat, PKV, Subrizi, F, Suhaili, N, Ward, DP, Bourdin, S, Dalby, PA, Hailes, HC, Hewitson, P, Ignatova, S, Kontoravdi, C, Leak, DJ, Shah, N, Sheppard, TD, Ward, JM, Lye, GJ

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Directed evolution of biocatalytic processes von Hibbert, Edward G., Baganz, Frank, Hailes, Helen C., Ward, John M., Lye, Gary J., Woodley, John M., Dalby, Paul A.

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Challenges in scaling up AAV-based gene therapy manufacturing von Jiang, Z, Dalby, PA

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