Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma von Chen, Ye, Xu, Liang, Mayakonda, Anand, Huang, Mo-Li, Kanojia, Deepika, Tan, Tuan Zea, Dakle, Pushkar, Lin, Ruby Yu-Tong, Ke, Xin-Yu, Said, Jonathan W., Chen, Jianxiang, Gery, Sigal, Ding, Ling-Wen, Jiang, Yan-Yi, Pang, Angela, Puhaindran, Mark Edward, Goh, Boon Cher, Koeffler, H. Phillip

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MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma von Ke, Xin-Yu, Chen, Ye, Tham, Valarie Yu-Yan, Lin, Ruby Yu-Tong, Dakle, Pushkar, Nacro, Kassoum, Puhaindran, Mark Edward, Houghton, Peter, Pang, Angela, Lee, Victor Kwanmin, Ding, Ling-Wen, Gery, Sigal, Hill, Jeffrey, Chen, Leilei, Xu, Liang, Koeffler, H. Phillip

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Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice von Han, Lin, Madan, Vikas, Mayakonda, Anand, Dakle, Pushkar, Woon, Teoh Weoi, Shyamsunder, Pavithra, Nordin, Hazimah Binte Mohd, Cao, Zeya, Sundaresan, Janani, Lei, Ienglam, Wang, Zhong, Koeffler, H. Phillip

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Proteolysis targeting chimeric molecules as therapy for multiple myeloma: efficacy, biomarker and drug combinations von Lim, Su Lin, Damnernsawad, Alisa, Shyamsunder, Pavithra, Chng, Wee Joo, Han, Bing Chen, Xu, Liang, Pan, Jian, Pravin, Dakle Pushkar, Alkan, Serhan, Tyner, Jeffrey W, Koeffler, H Phillip

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Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT) von Kusuma, Frances Karla, Prabhu, Aishvaryaa, Tieo, Galen, Ahmed, Syed Moiz, Dakle, Pushkar, Yong, Wai Khang, Pathak, Elina, Madan, Vikas, Jiang, Yan Yi, Tam, Wai Leong, Kappei, Dennis, Dröge, Peter, Koeffler, H. Phillip, Jeitany, Maya

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Novel carfilzomib-based combinations as potential therapeutic strategies for liposarcomas von Jeitany, Maya, Prabhu, Aishvaryaa, Dakle, Pushkar, Pathak, Elina, Madan, Vikas, Kanojia, Deepika, Mukundan, Vineeth, Jiang, Yan Yi, Landesman, Yosef, Tam, Wai Leong, Kappei, Dennis, Koeffler, H. Phillip

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ZRSR1 co-operates with ZRSR2 in regulating splicing of U12-type introns in murine hematopoietic cells von Madan, Vikas, Cao, Zeya, Teoh, Weoi Woon, Dakle, Pushkar, Han, Lin, Shyamsunder, Pavithra, Jeitany, Maya, Zhou, Siqin, Li, Jia, Nordin, Hazimah Binte Mohd, Shi, JiZhong, Yu, Shuizhou, Yang, Henry, Hossain, Md Zakir, Chng, Wee Joo, Koeffler, H Phillip

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RNA-Binding Protein ZFP36L1 Suppresses Hypoxia and Cell-Cycle Signaling von Loh, Xin-Yi, Sun, Qiao-Yang, Ding, Ling-Wen, Mayakonda, Anand, Venkatachalam, Nachiyappan, Yeo, Mei-Shi, Silva, Tiago C., Xiao, Jin-Fen, Doan, Ngan B., Said, Jonathan W., Ran, Xue-Bin, Zhou, Si-Qin, Dakle, Pushkar, Shyamsunder, Pavithra, Koh, Angele Pei-Fern, Huang, Ruby Yun-Ju, Berman, Benjamin P., Tan, Soo-Yong, Yang, Henry, Lin, De-Chen, Koeffler, H. Phillip

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THZ531 Induces a State of BRCAness in Multiple Myeloma Cells: Synthetic Lethality with Combination Treatment of THZ 531 with DNA Repair Inhibitors von Shyamsunder, Pavithra, Sridharan, Shree Pooja, Madan, Vikas, Dakle, Pushkar, Zeya, Cao, Kanojia, Deepika, Chng, Wee-Joo, Ong, S Tiong, Koeffler, H Phillip

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Active maintenance of CD8+ T cell naivety through regulation of global genome architecture von Russ, Brendan E., Barugahare, Adele, Dakle, Pushkar, Tsyganov, Kirril, Quon, Sara, Yu, Bingfei, Li, Jasmine, Lee, Jason K.C., Olshansky, Moshe, He, Zhaohren, Harrison, Paul F., See, Michael, Nussing, Simone, Morey, Alison E., Udupa, Vibha A., Bennett, Taylah J., Kallies, Axel, Murre, Cornelis, Collas, Phillipe, Powell, David, Goldrath, Ananda W., Turner, Stephen J.

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CARD10 , a CEBPE target involved in granulocytic differentiation von Shyamsunder, Pavithra, Sankar, Haresh, Mayakonda, Anand, Han, Lin, Nordin, Hazimah Binte Mohd, Woon, Teoh Weoi, Shanmugasundaram, Mahalakshmi, Dakle, Pushkar, Madan, Vikas, Koeffler, H Phillip

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ASXL2 regulates hematopoiesis in mice and its deficiency promotes myeloid expansion von Madan, Vikas, Han, Lin, Hattori, Norimichi, Teoh, Weoi Woon, Mayakonda, Anand, Sun, Qiao-Yang, Ding, Ling-Wen, Binte Mohd Nordin, Hazimah, Lim, Su Lin, Shyamsunder, Pavithra, Dakle, Pushkar, Sundaresan, Janani, Doan, Ngan B, Sanada, Masashi, Sato-Otsubo, Aiko, Meggendorfer, Manja, Yang, Henry, Said, Jonathan W, Ogawa, Seishi, Haferlach, Torsten, Liang, Der-Cherng, Shih, Lee-Yung, Nakamaki, Tsuyoshi, Wang, Q Tian, Koeffler, H Phillip

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TP63, SOX2, and KLF5 Establish a Core Regulatory Circuitry That Controls Epigenetic and Transcription Patterns in Esophageal Squamous Cell Carcinoma Cell Lines von Jiang, Yan-Yi, Jiang, Yuan, Li, Chun-Quan, Zhang, Ying, Dakle, Pushkar, Kaur, Harvinder, Deng, Jian-Wen, Lin, Ruby Yu-Tong, Han, Lin, Xie, Jian-Jun, Yan, Yiwu, Doan, Ngan, Zheng, Yueyuan, Mayakonda, Anand, Hazawa, Masaharu, Xu, Liang, Li, YanYu, Aswad, Luay, Jeitany, Maya, Kanojia, Deepika, Guan, Xin-Yuan, Said, Jonathan W., Yang, Wei, Fullwood, Melissa J., Lin, De-Chen, Koeffler, H. Phillip

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Identification of a novel enhancer of CEBPE essential for granulocytic differentiation von Shyamsunder, Pavithra, Shanmugasundaram, Mahalakshmi, Mayakonda, Anand, Dakle, Pushkar, Teoh, Weoi Woon, Han, Lin, Kanojia, Deepika, Lim, Mei Chee, Fullwood, Melissa, An, Omer, Yang, Henry, Shi, Jizhong, Hossain, Mohammad Zakir, Madan, Vikas, Koeffler, H. Phillip

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PML-RAR Binds to the +7kb Enhancer of CEBPE and Inhibits Its Expression von Shyamsunder, Pavithra, Sridharan, Shree Pooja, Dakle, Pushkar, Cao, Zeya, Madan, Vikas, Ong, Sin Tiong, Koeffler, H. Phillip

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Transcriptome analysis identifies TODL as a novel lncRNA associated with proliferation, differentiation, and tumorigenesis in liposarcoma through FOXM1 von Kanojia, Deepika, Kirtonia, Anuradha, Srujana, Namburi Sai Valli, Jeevanandan, Sree Priyanka, Shyamsunder, Pavithra, Sampath, Shruthi Sanjitha, Dakle, Pushkar, Mayakonda, Anand, Kaur, Harvinder, Yanyi, Jiang, Koeffler, H.Phillip, Garg, Manoj

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Abstract 2438: Genetic activation of JUN fuels the core regulatory circuitry of de-differentiated liposarcoma von Chen, Ye, Dakle, Pushkar, Tan, Tuan Zea, Lin, Ruby Yu-Tong, Puhaindran, Mark E., Gery, Sigal, Xu, Liang, Koeffler, Phillip H.

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Targeting RNA Exonuclease XRN1 Potentiates Efficacy of Cancer Immunotherapy von Ran, Xue-Bin, Ding, Ling-Wen, Sun, Qiao-Yang, Yang, Henry, Said, Jonathan W, Zhentang, Lao, Madan, Vikas, Dakle, Pushkar, Xiao, Jin-Fen, Loh, Xinyi, Li, Ying, Xu, Liang, Xiang, Xiao-Qiang, Wang, Ling-Zhi, Goh, Boon Cher, Lin, De-Chen, Chng, Wee Joo, Tan, Soo-Yong, Jha, Sudhakar, Koeffler, H Phillip

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Genetic variations in olfactory receptor gene OR2AG2 in a large multigenerational family with asthma von Chakraborty, Samarpana, Dakle, Pushkar, Sinha, Anirban, Vishweswaraiah, Sangeetha, Nagori, Aditya, Salimath, Shivalingaswamy, Prakash, Y. S., Lodha, R., Kabra, S. K., Ghosh, Balaram, Faruq, Mohammed, Mahesh, P. A., Agrawal, Anurag

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ZRSR1 Cooperates with ZRSR2 in Regulating Splicing of U12-Type Introns in Murine Hematopoietic Cells von Cao, Zeya, Madan, Vikas, Teoh, Weoi Woon, Dakle, Pushkar, Han, Lin, Shyamsunder, Pavithra, Zhou, Siqin, Li, Jia, Nordin, Hazimah Binte Mohd, Jizhong, Shi, Shuizhou, Yu, Yang, Henry, Hossain, Md Zakir, Chng, Wee-Joo, Koeffler, H. Phillip

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