Subcellular Compartmentation and Differential Catalytic Properties of the Three Human Nicotinamide Mononucleotide Adenylyltransferase Isoforms von Berger, Felicitas, Lau, Corinna, Dahlmann, Mathias, Ziegler, Mathias

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MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer von Imbastari, Francesca, Dahlmann, Mathias, Sporbert, Anje, Mattioli, Camilla Ciolli, Mari, Tommaso, Scholz, Florian, Timm, Lena, Twamley, Shailey, Migotti, Rebekka, Walther, Wolfgang, Dittmar, Gunnar, Rehm, Armin, Stein, Ulrike

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S100A4 in Cancer Metastasis: Wnt Signaling-Driven Interventions for Metastasis Restriction von Dahlmann, Mathias, Kobelt, Dennis, Walther, Wolfgang, Mudduluru, Giridhar, Stein, Ulrike

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Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1 von Juneja, Manisha, Kobelt, Dennis, Walther, Wolfgang, Voss, Cynthia, Smith, Janice, Specker, Edgar, Neuenschwander, Martin, Gohlke, Björn-Oliver, Dahlmann, Mathias, Radetzki, Silke, Preissner, Robert, von Kries, Jens Peter, Schlag, Peter Michael, Stein, Ulrike

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The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis von Kobelt, Dennis, Perez-Hernandez, Daniel, Fleuter, Claudia, Dahlmann, Mathias, Zincke, Fabian, Smith, Janice, Migotti, Rebekka, Popp, Oliver, Burock, Susen, Walther, Wolfgang, Dittmar, Gunnar, Mertins, Philipp, Stein, Ulrike

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MACC1 — more than metastasis? Facts and predictions about a novel gene von Stein, Ulrike, Dahlmann, Mathias, Walther, Wolfgang

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Restoring Treatment Response in Colorectal Cancer Cells by Targeting MACC1-Dependent ABCB1 Expression in Combination Therapy von Dahlmann, Mathias, Werner, Rebecca, Kortuem, Benedikt, Kobelt, Dennis, Walther, Wolfgang, Stein, Ulrike

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Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models von Dahlmann, Mathias, Gambara, Guido, Brzezicha, Bernadette, Popp, Oliver, Pachmayr, Eva, Wedeken, Lena, Pflaume, Alina, Mokritzkij, Margarita, Guel-Klein, Safak, Brandl, Andreas, Schweiger-Eisbacher, Caroline, Mertins, Philipp, Hoffmann, Jens, Keilholz, Ulrich, Walther, Wolfgang, Regenbrecht, Christian, Rau, Beate, Stein, Ulrike

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Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures von Alcaniz, Joshua, Winkler, Lars, Dahlmann, Mathias, Becker, Michael, Orthmann, Andrea, Haybaeck, Johannes, Krassnig, Stefanie, Skofler, Christina, Kratzsch, Tobias, Kuhn, Susanne A, Jödicke, Andreas, Linnebacher, Michael, Fichtner, Iduna, Walther, Wolfgang, Hoffmann, Jens

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MACC1 driven alterations in cellular biomechanics facilitate cell motility in glioblastoma von Hohmann, Tim, Hohmann, Urszula, Kolbe, Marc R., Dahlmann, Mathias, Kobelt, Dennis, Stein, Ulrike, Dehghani, Faramarz

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RAGE Mediates the Pro-Migratory Response of Extracellular S100A4 in Human Thyroid Cancer Cells von Medapati, Manoj Reddy, Dahlmann, Mathias, Ghavami, Saeid, Pathak, Kumar Alok, Lucman, Lydia, Klonisch, Thomas, Hoang-Vu, Cuong, Stein, Ulrike, Hombach-Klonisch, Sabine

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A Molecularly Characterized Preclinical Platform of Subcutaneous Renal Cell Carcinoma (RCC) Patient-Derived Xenograft Models to Evaluate Novel Treatment Strategies von Gürgen, Dennis, Becker, Michael, Dahlmann, Mathias, Flechsig, Susanne, Schaeffeler, Elke, Büttner, Florian A., Schmees, Christian, Bohnert, Regina, Bedke, Jens, Schwab, Matthias, Wendler, Johann J., Schostak, Martin, Jandrig, Burkhard, Walther, Wolfgang, Hoffmann, Jens

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RNA Interference for Antimetastatic Therapy von Dahlmann, Mathias, Stein, Ulrike

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Calcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker von Schmid, Felicitas, Dahlmann, Mathias, Röhrich, Hanna, Kobelt, Dennis, Hoffmann, Jens, Burock, Susen, Walther, Wolfgang, Stein, Ulrike

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MACC1—the first decade of a key metastasis molecule from gene discovery to clinical translation von Radhakrishnan, Harikrishnan, Walther, Wolfgang, Zincke, Fabian, Kobelt, Dennis, Imbastari, Francesca, Erdem, Müge, Kortüm, Benedikt, Dahlmann, Mathias, Stein, Ulrike

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A Bioinformatic Pipeline to Identify Biomarkers for Metastasis Formation from RNA Sequencing Data von Dahlmann, Mathias, Stein, Ulrike S.

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Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis von Kortüm, Benedikt, Radhakrishnan, Harikrishnan, Zincke, Fabian, Sachse, Christoph, Burock, Susen, Keilholz, Ulrich, Dahlmann, Mathias, Walther, Wolfgang, Dittmar, Gunnar, Kobelt, Dennis, Stein, Ulrike

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Core-Clock Genes Regulate Proliferation and Invasion via a Reciprocal Interplay with MACC1 in Colorectal Cancer Cells von Basti, Alireza, Malhan, Deeksha, Dumbani, Malti, Dahlmann, Mathias, Stein, Ulrike, Relógio, Angela

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MACC1-Induced Collective Migration Is Promoted by Proliferation Rather Than Single Cell Biomechanics von Hohmann, Tim, Hohmann, Urszula, Dahlmann, Mathias, Kobelt, Dennis, Stein, Ulrike, Dehghani, Faramarz

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RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis von Dahlmann, Mathias, Okhrimenko, Anna, Marcinkowski, Patrick, Osterland, Marc, Herrmann, Pia, Smith, Janice, Heizmann, Claus W, Schlag, Peter M, Stein, Ulrike

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