Anti-Angiogenics: Current Situation and Future Perspectives von Zirlik, Katja, Duyster, Justus

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HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice von Hoefflin, Rouven, Harlander, Sabine, Schäfer, Silvia, Metzger, Patrick, Kuo, Fengshen, Schönenberger, Désirée, Adlesic, Mojca, Peighambari, Asin, Seidel, Philipp, Chen, Chia-yi, Consenza-Contreras, Miguel, Jud, Andreas, Lahrmann, Bernd, Grabe, Niels, Heide, Danijela, Uhl, Franziska M., Chan, Timothy A., Duyster, Justus, Zeiser, Robert, Schell, Christoph, Heikenwalder, Mathias, Schilling, Oliver, Hakimi, A. Ari, Boerries, Melanie, Frew, Ian J.

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Demethylating therapy increases anti-CD123 CAR T cell cytotoxicity against acute myeloid leukemia von El Khawanky, Nadia, Hughes, Amy, Yu, Wenbo, Myburgh, Renier, Matschulla, Tony, Taromi, Sanaz, Aumann, Konrad, Clarson, Jade, Vinnakota, Janaki Manoja, Shoumariyeh, Khalid, Miething, Cornelius, Lopez, Angel F., Brown, Michael P., Duyster, Justus, Hein, Lutz, Manz, Markus G., Hughes, Timothy P., White, Deborah L., Yong, Agnes S. M., Zeiser, Robert

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Combination of Lenvatinib and Pembrolizumab Is an Effective Treatment Option for Anaplastic and Poorly Differentiated Thyroid Carcinoma von Dierks, Christine, Seufert, Jochen, Aumann, Konrad, Ruf, Juri, Klein, Claudius, Kiefer, Selina, Rassner, Michael, Boerries, Melanie, Zielke, Andreas, la Rosee, Paul, Meyer, Philipp Tobias, Kroiss, Matthias, Weißenberger, Christian, Schumacher, Tilmann, Metzger, Patrick, Weiss, Harald, Smaxwil, Constantin, Laubner, Katharina, Duyster, Justus, von Bubnoff, Nikolas, Miething, Cornelius, Thomusch, Oliver

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Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease von Spoerl, Silvia, Mathew, Nimitha R., Bscheider, Michael, Schmitt-Graeff, Annette, Chen, Sophia, Mueller, Tony, Verbeek, Mareike, Fischer, Julius, Otten, Vera, Schmickl, Martina, Maas-Bauer, Kristina, Finke, Jürgen, Peschel, Christian, Duyster, Justus, Poeck, Hendrik, Zeiser, Robert, von Bubnoff, Nikolas

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Activating JAK-mutations confer resistance to FLT3 kinase inhibitors in FLT3-ITD positive AML in vitro and in vivo von Rummelt, Christoph, Gorantla, Sivahari P., Meggendorfer, Manja, Charlet, Anne, Endres, Cornelia, Döhner, Konstanze, Heidel, Florian H., Fischer, Thomas, Haferlach, Torsten, Duyster, Justus, von Bubnoff, Nikolas

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Allogeneic transplantation of multiple myeloma patients may allow long-term survival in carefully selected patients with acceptable toxicity and preserved quality of life von Greil, Christine, Engelhardt, Monika, Ihorst, Gabriele, Schoeller, Katja, Bertz, Hartmut, Marks, Reinhard, Zeiser, Robert, Duyster, Justus, Einsele, Hermann, Finke, Jürgen, Wäsch, Ralph

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Functional Analysis of Epidermal Growth Factor Receptor (EGFR) Mutations and Potential Implications for EGFR Targeted Therapy von KANCHA, Rama Krishna, VON BUBNOFF, Nikolas, PESCHEL, Christian, DUYSTER, Justus

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Sorafenib in Combination With Intensive Chemotherapy in Elderly Patients With Acute Myeloid Leukemia: Results From a Randomized, Placebo-Controlled Trial von SERVE, Hubert, KRUG, Utz, FISCHER, Thomas, GIAGOUNIDIS, Aristoteles, NEUBAUER, Andreas, REICHLE, Albrecht, AULITZKY, Walter, NOPPENEY, Richard, BLAU, Igor, KUNZMANN, Volker, STUHLMANN, Reingard, KRÄMER, Alwin, WAGNER, Ruth, KREUZER, Karl-Anton, BRANDTS, Christian, STEFFEN, Björn, THIEDE, Christian, MÜLLER-TIDOW, Carsten, EHNINGER, Gerhard, BERDEL, Wolfgang E, SAUERLAND, M. Cristina, HEINECKE, Achim, BRUNNBERG, Uta, SCHAICH, Markus, OTTMANN, Oliver, DUYSTER, Justus, WANDT, Hannes

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Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage von Schwab, Lukas, Goroncy, Luise, Palaniyandi, Senthilnathan, Gautam, Sanjivan, Triantafyllopoulou, Antigoni, Mocsai, Attila, Reichardt, Wilfried, Karlsson, Fridrik J, Radhakrishnan, Sabarinath V, Hanke, Kathrin, Schmitt-Graeff, Annette, Freudenberg, Marina, von Loewenich, Friederike D, Wolf, Philipp, Leonhardt, Franziska, Baxan, Nicoleta, Pfeifer, Dietmar, Schmah, Oliver, Schönle, Anne, Martin, Stefan F, Mertelsmann, Roland, Duyster, Justus, Finke, Jürgen, Prinz, Marco, Henneke, Philipp, Häcker, Hans, Hildebrandt, Gerhard C, Häcker, Georg, Zeiser, Robert

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MicroRNA-155–deficient dendritic cells cause less severe GVHD through reduced migration and defective inflammasome activation von Chen, Sophia, Smith, Benjamin A.H., Iype, Joseena, Prestipino, Alessandro, Pfeifer, Dietmar, Grundmann, Sebastian, Schmitt-Graeff, Annette, Idzko, Marco, Beck, Yvonne, Prinz, Gabriele, Finke, Jürgen, Duyster, Justus, Zeiser, Robert

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Ruxolitinib in GvHD (RIG) study: a multicenter, randomized phase 2 trial to determine the response rate of Ruxolitinib and best available treatment (BAT) versus BAT in steroid-refr... von von Bubnoff, Nikolas, Ihorst, Gabriele, Grishina, Olga, Röthling, Nadine, Bertz, Hartmut, Duyster, Justus, Finke, Jürgen, Zeiser, Robert

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Donor lymphocyte infusions after first allogeneic hematopoietic stem-cell transplantation in adults with acute myeloid leukemia: a single-center landmark analysis von Rettig, Andrés R., Ihorst, Gabriele, Bertz, Hartmut, Lübbert, Michael, Marks, Reinhard, Waterhouse, Miguel, Wäsch, Ralph, Zeiser, Robert, Duyster, Justus, Finke, Jürgen

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The IL-3, IL-5, and GM-CSF common receptor beta chain mediates oncogenic activity of FLT3-ITD-positive AML von Charlet, Anne, Kappenstein, Max, Keye, Philip, Kläsener, Kathrin, Endres, Cornelia, Poggio, Teresa, Gorantla, Sivahari P., Kreutmair, Stefanie, Sänger, Jana, Illert, Anna L., Miething, Cornelius, Reth, Michael, Duyster, Justus, Rummelt, Christoph, von Bubnoff, Nikolas

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The Nlrp3 inflammasome regulates acute graft-versus-host disease von Jankovic, Dragana, Ganesan, Jayanthi, Bscheider, Michael, Stickel, Natalie, Weber, Felix C, Guarda, Greta, Follo, Marie, Pfeifer, Dietmar, Tardivel, Aubry, Ludigs, Kristina, Bouazzaoui, Abdellatif, Kerl, Katrin, Fischer, Julius C, Haas, Tobias, Schmitt-Gräff, Annette, Manoharan, Anand, Müller, Leonard, Finke, Jürgen, Martin, Stefan F, Gorka, Oliver, Peschel, Christian, Ruland, Jürgen, Idzko, Marco, Duyster, Justus, Holler, Ernst, French, Lars E, Poeck, Hendrik, Contassot, Emmanuel, Zeiser, Robert

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Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia von Mathew, Nimitha R, Vinnakota, Janaki M, Apostolova, Petya, Erny, Daniel, Hamarsheh, Shaimaa, Andrieux, Geoffroy, Kim, Jung-Seok, Hanke, Kathrin, Goldmann, Tobias, Chappell-Maor, Louise, El-Khawanky, Nadia, Ihorst, Gabriele, Schmidt, Dominik, Duyster, Justus, Finke, Jürgen, Blank, Thomas, Boerries, Melanie, Blazar, Bruce R, Jung, Steffen, Prinz, Marco, Zeiser, Robert

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Early assessment of circulating tumor DNA after curative‐intent resection predicts tumor recurrence in early‐stage and locally advanced non‐small‐cell lung cancer von Waldeck, Silvia, Mitschke, Jan, Wiesemann, Sebastian, Rassner, Michael, Andrieux, Geoffroy, Deuter, Max, Mutter, Jurik, Lüchtenborg, Anne‐Marie, Kottmann, Daniel, Titze, Laurin, Zeisel, Christoph, Jolic, Martina, Philipp, Ulrike, Lassmann, Silke, Bronsert, Peter, Greil, Christine, Rawluk, Justyna, Becker, Heiko, Isbell, Lisa, Müller, Alexandra, Doostkam, Soroush, Passlick, Bernward, Börries, Melanie, Duyster, Justus, Wehrle, Julius, Scherer, Florian, von Bubnoff, Nikolas

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Bile acids regulate intestinal antigen presentation and reduce graft-versus-host disease without impairing the graft-versus-leukemia effect von Haring, Eileen, Uhl, Franziska M, Andrieux, Geoffroy, Proietti, Michele, Bulashevska, Alla, Sauer, Barbara, Braun, Lukas M, de Vega Gomez, Enrique, Esser, Philipp R, Martin, Stefan F, Pfeifer, Dietmar, Follo, Marie, Schmitt-Graeff, Annette, Buescher, Joerg, Duyster, Justus, Grimbacher, Bodo, Boerries, Melanie, Pearce, Erika L, Zeiser, Robert, Apostolova, Petya

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Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib von Kancha, Rama Krishna, von Bubnoff, Nikolas, Bartosch, Natalie, Peschel, Christian, Engh, Richard A, Duyster, Justus

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A newly identified 45‐kDa JAK2 variant with an altered kinase domain structure represents a novel mode of JAK2 kinase inhibitor resistance von Gorantla, Sivahari Prasad, Mueller, Tony Andreas, Albers‐Leischner, Corinna, Rudelius, Martina, Bubnoff, Nikolas, Duyster, Justus

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