The Syk inhibitor R406 is a modulator of P-glycoprotein (ABCB1)-mediated multidrug resistance von Duran, George E, Sikic, Branimir I

Volltext

The miR-200 family differentially regulates sensitivity to paclitaxel and carboplatin in human ovarian carcinoma OVCAR-3 and MES-OV cells von Brozovic, Anamaria, Duran, George E., Wang, Yan C., Francisco, E. Brian, Sikic, Branimir I.

Volltext

Mechanisms of resistance to cabazitaxel von Duran, George E, Wang, Yan C, Francisco, E Brian, Rose, John C, Martinez, Francisco J, Coller, John, Brassard, Diana, Vrignaud, Patricia, Sikic, Branimir I

Volltext

Cabazitaxel is more active than first-generation taxanes in ABCB1(+) cell lines due to its reduced affinity for P-glycoprotein von Duran, George E., Derdau, Volker, Weitz, Dietmar, Philippe, Nicolas, Blankenstein, Jörg, Atzrodt, Jens, Sémiond, Dorothée, Gianolio, Diego A., Macé, Sandrine, Sikic, Branimir I.

Volltext

Single-cell RNA-sequencing reveals predictive features of response to pembrolizumab in Sézary syndrome von Su, Tianying, Duran, George E., Kwang, Alexa C., Ramchurren, Nirasha, Fling, Steven P., Kim, Youn H., Khodadoust, Michael S.

Volltext

Resistance to mogamulizumab is associated with loss of CCR4 in cutaneous T-cell lymphoma von Beygi, Sara, Duran, George E, Fernandez-Pol, Sebastian, Rook, Alain H, Kim, Youn H, Khodadoust, Michael S

Volltext

Expression and silencing of the microtubule-associated protein Tau in breast cancer cells von Spicakova, Tatiana, O'Brien, Maureen M, Duran, George E, Sweet-Cordero, Alejandro, Sikic, Branimir I

Volltext

Decreased levels of baseline and drug-induced tubulin polymerisation are hallmarks of resistance to taxanes in ovarian cancer cells and are associated with epithelial-to-mesenchyma... von Duran, George E, Wang, Yan C, Moisan, François, Francisco, E Brian, Sikic, Branimir I

Volltext

Gene Expression Profiling Differentiates Germ Cell Tumors from Other Cancers and Defines Subtype-Specific Signatures von Dejan Juric, Sanja Sale, Hromas, Robert A., Ron Yu, Wang, Yan, George E. Duran, Tibshirani, Robert, Einhorn, Lawrence H., Sikic, Branimir I.

Volltext

Carboplatin-induced upregulation of pan β-tubulin and class III β-tubulin is implicated in acquired resistance and cross-resistance of ovarian cancer von Pernar Kovač, Margareta, Tadić, Vanja, Kralj, Juran, Duran, George E., Stefanelli, Alessia, Stupin Polančec, Darija, Dabelić, Sanja, Bačić, Niko, Tomicic, Maja T., Heffeter, Petra, Sikic, Branimir I., Brozovic, Anamaria

Volltext

Enhancement of paclitaxel and carboplatin therapies by CCL2 blockade in ovarian cancers von Moisan, Francois, Francisco, Edgar B., Brozovic, Anamaria, Duran, George E., Wang, Yan C., Chaturvedi, Shalini, Seetharam, Shobha, Snyder, Linda A., Doshi, Parul, Sikic, Branimir I.

Volltext

Abstract 2140: Cabazitaxel is more active than first generation taxanes in ABCB1 (+) cell lines due to its higher intracellular accumulation and reduction in ATPase stimulation von Duran, George E., Weitz, Dietmar, Sémiond, Dorothée, Gianolio, Diego, Macé, Sandrine, Sikic, Branimir I.

Volltext

Multi-omic profiling reveals the endogenous and neoplastic responses to immunotherapies in cutaneous T cell lymphoma von Glass, David R., Mayer-Blackwell, Koshlan, Ramchurren, Nirasha, Parks, K. Rachael, Duran, George E., Wright, Anna K., Bastidas Torres, Armando N., Islas, Laura, Kim, Youn H., Fling, Steven P., Khodadoust, Michael S., Newell, Evan W.

Volltext

Gene expression patterns in ovarian carcinomas von Schaner, Marci E, Ross, Douglas T, Ciaravino, Giuseppe, Sorlie, Therese, Troyanskaya, Olga, Diehn, Maximilian, Wang, Yan C, Duran, George E, Sikic, Thomas L, Caldeira, Sandra, Skomedal, Hanne, Tu, I-Ping, Hernandez-Boussard, Tina, Johnson, Steven W, O'Dwyer, Peter J, Fero, Michael J, Kristensen, Gunnar B, Borresen-Dale, Anne-Lise, Hastie, Trevor, Tibshirani, Robert, van de Rijn, Matt, Teng, Nelson N, Longacre, Teri A, Botstein, David, Brown, Patrick O, Sikic, Branimir I

Volltext

Monosomy of Chromosome 10 Associated With Dysregulation of Epidermal Growth Factor Signaling in Glioblastomas von Yadav, Ajay K, Renfrow, Jaclyn J, Scholtens, Denise M, Xie, Hehuang, Duran, George E, Bredel, Claudia, Vogel, Hannes, Chandler, James P, Chakravarti, Arnab, Robe, Pierre A, Das, Sunit, Scheck, Adrienne C, Kessler, John A, Soares, Marcelo B, Sikic, Branimir I, Harsh, Griffith R, Bredel, Markus

Volltext

Abstract 4001: The anti-CD47 antibody Hu5F9-G4 activates macrophages and inhibits ovarian cancer xenografts, alone and in combination with chemotherapy or immunotherapy von Kathawala, Rishil J., Mundy, David C., Duran, George E., Volkmer, Jens-Peter, Kao, Kevin S., Wang, Yan C., Bellary, Aditi, Weissman, Irving L., Sikic, Branimir I.

Volltext

Genomic stability at the coding regions of the multidrug transporter gene ABCB1 : insights into the development of alternative drug resistance mechanisms in human leukemia cells von Chen, Kevin G, Duran, George E, Mogul, Mark J, Wang, Yan C, Ross, Kevin L, Jaffrézou, Jean-Pierre, Huff, Lyn M, Johnson, Kory R, Fojo, Tito, Lacayo, Norman J, Sikic, Branimir I

Volltext

A phase I trial of continuous infusion of the multidrug resistance inhibitor zosuquidar with daunorubicin and cytarabine in acute myeloid leukemia von Lancet, Jeffrey E, Baer, Maria R, Duran, George E, List, Alan F, Fielding, Robert, Marcelletti, John F, Multani, Pratik S, Sikic, Branimir I

Volltext

Genetic and epigenetic modeling of the origins of multidrug-resistant cells in a human sarcoma cell line von CHEN, Kevin G, WANG, Yan C, SIKIC, Branimir I, SCHANER, Marci E, FRANCISCO, Brian, DURAN, George E, JURIC, Dejan, HUFF, Lyn M, PADILLA-NASH, Hesed, RIED, Thomas, FOJO, Tito

Volltext

Regional activation of chromosomal arm 7q with and without gene amplification in taxane-selected human ovarian cancer cell lines von Wang, Yan C., Juric, Dejan, Francisco, Brian, Yu, Ron X., Duran, George E., Chen, G. Kevin, Chen, Xin, Sikic, Branimir I.

Volltext