Th17 cytokines and their emerging roles in inflammation and autoimmunity von Fouser, Lynette A., Wright, Jill F., Dunussi-Joannopoulos, Kyriaki, Collins, Mary

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Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides von Liang, Spencer C, Tan, Xiang-Yang, Luxenberg, Deborah P, Karim, Riyez, Dunussi-Joannopoulos, Kyriaki, Collins, Mary, Fouser, Lynette A

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IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation von Ma, Hak-Ling, Liang, Spencer, Li, Jing, Napierata, Lee, Brown, Tom, Benoit, Stephen, Senices, Mayra, Gill, Davinder, Dunussi-Joannopoulos, Kyriaki, Collins, Mary, Nickerson-Nutter, Cheryl, Fouser, Lynette A, Young, Deborah A

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An IL-17F/A Heterodimer Protein Is Produced by Mouse Th17 Cells and Induces Airway Neutrophil Recruitment von Liang, Spencer C, Long, Andrew J, Bennett, Frann, Whitters, Matthew J, Karim, Riyez, Collins, Mary, Goldman, Samuel J, Dunussi-Joannopoulos, Kyriaki, Williams, Cara M. M, Wright, Jill F, Fouser, Lynette A

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IL-22 induces an acute-phase response von Liang, Spencer C, Nickerson-Nutter, Cheryl, Pittman, Debra D, Carrier, Yijun, Goodwin, Debra G, Shields, Kathleen M, Lambert, Andre-Jean, Schelling, Scott H, Medley, Quintus G, Ma, Hak-Ling, Collins, Mary, Dunussi-Joannopoulos, Kyriaki, Fouser, Lynette A

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Tumor cells secreting IL‐13 but not IL‐13Rα2 fusion protein have reduced tumorigenicity in vivo von Ma, Hak‐Ling, Whitters, Matthew J., Jacobson, Bruce A., Donaldson, Deborah D., Collins, Mary, Dunussi‐Joannopoulos, Kyriaki

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IL-22R, IL-10R2, and IL-22BP Binding Sites Are Topologically Juxtaposed on Adjacent and Overlapping Surfaces of IL-22 von Wu, Paul W., Li, Jing, Kodangattil, Sreekumar R., Luxenberg, Deborah P., Bennett, Frann, Martino, Margot, Collins, Mary, Dunussi-Joannopoulos, Kyriaki, Gill, Davinder S., Wolfman, Neil M., Fouser, Lynette A.

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Phosphatidylcholine and Phosphatidylethanolamine Behave as Substrates of the Human MDR1 P-Glycoprotein von Bosch, Irene, Dunussi-Joannopoulos, Kyriaki, Wu, Rui-Lian, Furlong, Stephen T, Croop, James

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B7.2-Ig fusion proteins enhance IL-4-dependent differentiation of tumor-sensitized CD8+ cytotoxic T lymphocyte precursors von Hiraoka, Shin-ichiro, Takeuchi, Noritami, Bian, Yang, Nakahara, Hirokazu, Kogo, Mikihiko, Dunussi-Joannopoulos, Kyriaki, Wolf, Stanley, Ono, Shiro, Fujiwara, Hiromi

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Mitoxantrone, Etoposide, and Cyclosporine Therapy in Pediatric Patients With Recurrent or Refractory Acute Myeloid Leukemia von DAHL, G. V, LACAYO, N. J, BROPHY, N, DUNUSSI-JOANNOPOULOS, K, WEINSTEIN, H. J, MYRON CHANG, SIKIC, B. I, ARCECI, R. J

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IL-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of IFN-gamma von Ma, Hak-Ling, Whitters, Matthew J, Konz, Richard F, Senices, Mayra, Young, Deborah A, Grusby, Michael J, Collins, Mary, Dunussi-Joannopoulos, Kyriaki

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A FLIPR-based Assay to Assess Potency of Inhibitors of the TEC Family Kinases Itk and Btk von Douhan, John, Principal Research Scientist, Wyeth Research, Inflammation, Cambridge, MA, Miyashiro, Joy, Research Scientist, Wyeth Research, Inflammation, Cambridge, MA, Zhou, Xiaochuan, Research Scientist, Wyeth Research, Inflammation, Cambridge, MA, Wu, Paul, Research Scientist, Wyeth Research, Inflammation, Cambridge, MA, Cole, Derek, Principal Research Scientist, Wyeth Research, Chemical and Screening Sciences, Pearl River, NY, Collins, Mary, Vice President, Wyeth Research, Inflammation, Cambridge, MA, Dunussi-Joannopoulos, Kyriaki, Associate Director, Wyeth Research, Inflammation, Cambridge, MA

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The capacity of the natural ligands for CD28 to drive IL-4 expression in naïve and antigen-primed CD4+ and CD8+ T cells von Bian, Yang, Hiraoka, Shin-Ichiro, Tomura, Michio, Zhou, Xu-Yu, Yashiro-Ohtani, Yumi, Mori, Yoshiko, Shimizu, Jun, Ono, Shiro, Dunussi-Joannopoulos, Kyriaki, Wolf, Stanley, Fujiwara, Hiromi

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Efficacious immunomodulatory activity of the chemokine stromal cell–derived factor 1 (SDF-1): local secretion of SDF-1 at the tumor site serves as T-cell chemoattractant and mediat... von Dunussi-Joannopoulos, Kyriaki, Zuberek, Krystyna, Runyon, Kathlene, Hawley, Robert G., Wong, Anthony, Erickson, Jamie, Herrmann, Steve, Leonard, John P.

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Gene Immunotherapy in Murine Acute Myeloid Leukemia: Granulocyte-Macrophage Colony-Stimulating Factor Tumor Cell Vaccines Elicit More Potent Antitumor Immunity Compared With B7 Fam... von Dunussi-Joannopoulos, Kyriaki, Dranoff, Glenn, Weinstein, Howard J., Ferrara, James L.M., Bierer, Barbara E., Croop, James M.

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The Combination of Chemotherapy and Systemic Immunotherapy and the Concept of Cure in Murine Leukemia and Lymphoma von Dunussi-Joannopoulos, Kyriaki

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Gene Immunotherapy in Murine Acute Myeloid Leukemia: Granulocyte-Macrophage Colony-Stimulating Factor Tumor Cell Vaccines Elicit More Potent Antitumor Immunity Compared With B7 Fam... von Dunussi-Joannopoulos, Kyriaki, Dranoff, Glenn, Weinstein, Howard J., Ferrara, James L.M., Bierer, Barbara E., Croop, James M.

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Vaccines With Interleukin-12–Transduced Acute Myeloid Leukemia Cells Elicit Very Potent Therapeutic and Long-Lasting Protective Immunity von Dunussi-Joannopoulos, Kyriaki, Runyon, Kathlene, Erickson, Jamie, Schaub, Robert G., Hawley, Robert G., Leonard, John P.

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Vaccines With Interleukin-12–Transduced Acute Myeloid Leukemia Cells Elicit Very Potent Therapeutic and Long-Lasting Protective Immunity von Dunussi-Joannopoulos, Kyriaki, Runyon, Kathlene, Erickson, Jamie, Schaub, Robert G., Hawley, Robert G., Leonard, John P.

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The combination of chemotherapy and systemic immunotherapy with soluble B7–immunoglobulin G leads to cure of murine leukemia and lymphoma and demonstration of tumor-specific memory... von Runyon, Kathlene, Lee, Kwang, Zuberek, Krystyna, Collins, Mary, Leonard, John P., Dunussi-Joannopoulos, Kyriaki

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