Minisci reactions: Versatile CH-functionalizations for medicinal chemists von Duncton, Matthew A. J

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Orally Absorbed Derivatives of the β‑Lactamase Inhibitor Avibactam. Design of Novel Prodrugs of Sulfate Containing Drugs von Gordon, Eric M, Duncton, Matthew A. J, Gallop, Mark A

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Synthesis of trans-2-(Trifluoromethyl)cyclopropanes via Suzuki Reactions with an N‑Methyliminodiacetic Acid Boronate von Duncton, Matthew A. J, Singh, Rajinder

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Tetrazolone as an acid bioisostere: application to marketed drugs containing a carboxylic acid von Duncton, Matthew A. J, Murray, Ryan B, Park, Gary, Singh, Rajinder

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A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonuclease 1 von Das, Debanu, Duncton, Matthew A J, Georgiadis, Taxiarchis M, Pellicena, Patricia, Clark, Jennifer, Sobol, Robert W, Georgiadis, Millie M, King-Underwood, John, Jobes, David V, Chang, Caleb, Gao, Yang, Deacon, Ashley M, Wilson, 3rd, David M

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A Single-Step Synthesis of Azetidine-3-amines von Wang, Brian J, Duncton, Matthew A J

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Identification and characterization of novel TRPV4 modulators von Vincent, Fabien, Acevedo, Alejandra, Nguyen, Margaret T., Dourado, Michelle, DeFalco, Jeff, Gustafson, Amy, Spiro, Peter, Emerling, Daniel E., Kelly, Michael G., Duncton, Matthew A.J.

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A one-pot synthesis of tetrazolones from acid chlorides: understanding functional group compatibility, and application to the late-stage functionalization of marketed drugs von Duncton, Matthew A. J, Singh, Rajinder

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Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response von Wilson, David M., Deacon, Ashley M., Duncton, Matthew A.J., Pellicena, Patricia, Georgiadis, Millie M., Yeh, Andrew P., Arvai, Andrew S., Moiani, Davide, Tainer, John A., Das, Debanu

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Preparation of Heteroaryloxetanes and Heteroarylazetidines by Use of a Minisci Reaction von Duncton, Matthew A. J, Estiarte, M. Angels, Johnson, Russell J, Cox, Matthew, O’Mahony, Donogh J. R, Edwards, William T, Kelly, Michael G

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Early Drug Discovery and Development of Novel Cancer Therapeutics Targeting DNA Polymerase Eta (POLH) von Wilson, David M, Duncton, Matthew A J, Chang, Caleb, Lee Luo, Christie, Georgiadis, Taxiarchis M, Pellicena, Patricia, Deacon, Ashley M, Gao, Yang, Das, Debanu

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5-Benzyloxytryptamine as an antagonist of TRPM8 von DeFalco, Jeff, Steiger, Daniel, Dourado, Michelle, Emerling, Daniel, Duncton, Matthew A.J.

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Enantioselective synthesis of an octahydroindolizine (indolizidine) alcohol using an enzymatic resolution von Zhang, Jing, Kolluri, Rao, Alvarez, Salvador G, Irving, Mark M, Singh, Rajinder, Duncton, Matthew A J

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Tuning the Reactivity of Nuclear Factor Erythroid 2‑Related Factor 2 (Nrf2) Activators for Optimal in Vivo Efficacy von Markovtsov, Vadim, Duncton, Matthew A. J., Bagos, Art, Yi, Sothy, Braselmann, Sylvia, Bhamidipati, Somasekhar, Darwish, Ihab S., Yu, Jiaxin, Owyang, Alexander M., Fernandez, Beth, Samant, Bhushan, Park, Gary, Masuda, Esteban S., Shaw, Simon J.

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Toward Orally Absorbed Prodrugs of the Antibiotic Aztreonam. Design of Novel Prodrugs of Sulfate Containing Drugs. Part 2 von Gordon, Eric M, Duncton, Matthew A. J, Wang, Brian J, Qi, Longwu, Fan, Dazhong, Li, Xianfeng, Ni, Zhi-Jie, Ding, Pingyu, Grygorash, Ruslan, Low, Eddy, Yu, Guijun, Sun, Jiawei

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Synthesis of 9-nitro-5H-spiro[benzo[b]tetrazolo[1,5-d][1,4]oxazepine-4,2′-oxirane] via an unusual ring-expansion von Kolluri, Rao, Zhang, Jing, Singh, Rajinder, Duncton, Matthew A.J.

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Identification of orally-bioavailable antagonists of the TRPV4 ion-channel von Wei, Zhi-Liang, Nguyen, Margaret T., O’Mahony, Donogh J.R., Acevedo, Alejandra, Zipfel, Sheila, Zhang, Qingling, Liu, Luna, Dourado, Michelle, Chi, Candace, Yip, Victor, DeFalco, Jeff, Gustafson, Amy, Emerling, Daniel E., Kelly, Michael G., Kincaid, John, Vincent, Fabien, Duncton, Matthew A.J.

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Preparation of Aryloxetanes and Arylazetidines by Use of an Alkyl−Aryl Suzuki Coupling von Duncton, Matthew A. J, Estiarte, M. Angels, Tan, Darlene, Kaub, Carl, O’Mahony, Donogh J. R, Johnson, Russell J, Cox, Matthew, Edwards, William T, Wan, Min, Kincaid, John, Kelly, Michael G

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A practical asymmetric synthesis of ortho-substituted 4-pyrazolyl-2-ethylamines von O'Mahony, Donogh J.R., Johnson, Russell J., Estiarte, M. Angels, Edwards, William T., Duncton, Matthew A.J.

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A concise one-pot synthesis of trifluoromethyl-containing 2,6-disubstituted 5,6,7,8-tetrahydroquinolines and 5,6,7,8-tetrahydronaphthyridines von Johnson, Russell J, O'Mahony, Donogh J R, Edwards, William T, Duncton, Matthew A J

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