Immunogenic and efficacious SARS-CoV-2 vaccine based on resistin-trimerized spike antigen SmT1 and SLA archaeosome adjuvant von Akache, Bassel, Renner, Tyler M., Tran, Anh, Deschatelets, Lise, Dudani, Renu, Harrison, Blair A., Duque, Diana, Haukenfrers, Julie, Rossotti, Martin A., Gaudreault, Francis, Hemraz, Usha D., Lam, Edmond, Régnier, Sophie, Chen, Wangxue, Gervais, Christian, Stuible, Matthew, Krishnan, Lakshmi, Durocher, Yves, McCluskie, Michael J.

Volltext

Sulfated archaeol glycolipids: Comparison with other immunological adjuvants in mice von Akache, Bassel, Stark, Felicity C, Jia, Yimei, Deschatelets, Lise, Dudani, Renu, Harrison, Blair A, Agbayani, Gerard, Williams, Dean, Jamshidi, Mohammad P, Krishnan, Lakshmi, McCluskie, Michael J

Volltext

Intranasal immunization with a proteosome-adjuvanted SARS-CoV-2 spike protein-based vaccine is immunogenic and efficacious in mice and hamsters von Stark, Felicity C., Akache, Bassel, Deschatelets, Lise, Tran, Anh, Stuible, Matthew, Durocher, Yves, McCluskie, Michael J., Agbayani, Gerard, Dudani, Renu, Harrison, Blair A., Renner, Tyler M., Makinen, Shawn R., Bavananthasivam, Jegarubee, Duque, Diana, Gagne, Martin, Zimmermann, Joseph, Zarley, C. David, Cochrane, Terrence R., Handfield, Martin

Volltext

Tuning the immune response: sulfated archaeal glycolipid archaeosomes as an effective vaccine adjuvant for induction of humoral and cell-mediated immunity towards the SARS-CoV-2 Om... von Renner, Tyler M, Akache, Bassel, Stuible, Matthew, Rohani, Nazanin, Cepero-Donates, Yuneivy, Deschatelets, Lise, Dudani, Renu, Harrison, Blair A, Baardsnes, Jason, Koyuturk, Izel, Hill, Jennifer J, Hemraz, Usha D, Régnier, Sophie, Lenferink, Anne E G, Durocher, Yves, McCluskie, Michael J

Volltext

Evaluation of Adjuvant Activity and Bio-Distribution of Archaeosomes Prepared Using Microfluidic Technology von Jia, Yimei, Agbayani, Gerard, Chandan, Vandana, Iqbal, Umar, Dudani, Renu, Qian, Hui, Jakubek, Zygmunt, Chan, Kenneth, Harrison, Blair, Deschatelets, Lise, Akache, Bassel, McCluskie, Michael J

Volltext

Blood-Based Immune Protein Markers of Disease Progression in Murine Models of Acute and Chronic Inflammatory Bowel Disease von Renner, Tyler Milston, Agbayani, Gerard, Dudani, Renu, McCluskie, Michael J, Akache, Bassel

Volltext

Immunogenicity of SARS-CoV-2 spike antigens derived from Beta & Delta variants of concern von Akache, Bassel, Renner, Tyler M., Stuible, Matthew, Rohani, Nazanin, Cepero-Donates, Yuneivy, Deschatelets, Lise, Dudani, Renu, Harrison, Blair A., Gervais, Christian, Hill, Jennifer J., Hemraz, Usha D., Lam, Edmond, Régnier, Sophie, Lenferink, Anne E. G., Durocher, Yves, McCluskie, Michael J.

Volltext

Preclinical evaluation of manufacturable SARS-CoV-2 spike virus-like particles produced in Chinese Hamster Ovary cells von Alpuche-Lazcano, Sergio P., Stuible, Matthew, Akache, Bassel, Tran, Anh, Kelly, John, Hrapovic, Sabahudin, Robotham, Anna, Haqqani, Arsalan, Star, Alexandra, Renner, Tyler M., Blouin, Julie, Maltais, Jean-Sébastien, Cass, Brian, Cui, Kai, Cho, Jae-Young, Wang, Xinyu, Zoubchenok, Daria, Dudani, Renu, Duque, Diana, McCluskie, Michael J., Durocher, Yves

Volltext

Sulfated Lactosyl Archaeol Archaeosomes Synergize with Poly(I:C) to Enhance the Immunogenicity and Efficacy of a Synthetic Long Peptide-Based Vaccine in a Melanoma Tumor Model von Akache, Bassel, Agbayani, Gerard, Stark, Felicity C, Jia, Yimei, Dudani, Renu, Harrison, Blair A, Deschatelets, Lise, Chandan, Vandana, Lam, Edmond, Hemraz, Usha D, Régnier, Sophie, Krishnan, Lakshmi, McCluskie, Michael J

Volltext

The Synergistic Effects of Sulfated Lactosyl Archaeol Archaeosomes When Combined with Different Adjuvants in a Murine Model von Jia, Yimei, Akache, Bassel, Agbayani, Gerard, Chandan, Vandana, Dudani, Renu, Harrison, Blair A, Deschatelets, Lise, Hemraz, Usha D, Lam, Edmond, Régnier, Sophie, Stark, Felicity C, Krishnan, Lakshmi, McCluskie, Michael J

Volltext

Sulfated Lactosyl Archaeol Archaeosome-Adjuvanted Vaccine Formulations Targeting Rabbit Hemorrhagic Disease Virus Are Immunogenic and Efficacious von Akache, Bassel, Read, Andrew J, Dudani, Renu, Harrison, Blair A, Williams, Dean, Deschatelets, Lise, Jia, Yimei, Chandan, Vandana, Stark, Felicity C, Agbayani, Gerard, Makinen, Shawn R, Hemraz, Usha D, Lam, Edmond, Régnier, Sophie, Zou, Wei, Kirkland, Peter D, McCluskie, Michael J

Volltext

Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium von Robinson, Nirmal, McComb, Scott, Mulligan, Rebecca, Dudani, Renu, Krishnan, Lakshmi, Sad, Subash

Volltext

An Archaeosome-Adjuvanted Vaccine and Checkpoint Inhibitor Therapy Combination Significantly Enhances Protection from Murine Melanoma von Stark, Felicity C, Weeratna, Risini D, Deschatelets, Lise, Gurnani, Komal, Dudani, Renu, McCluskie, Michael J, Krishnan, Lakshmi

Volltext

Modulation of Antigenic Location Converts Chronic into Acute Infection by Forcing CD8+ T Cell Recognition von Tzelepis, Fanny, Alcon, Valeria, Dudani, Renu, Gurnani, Komal, Zafer, Ahmed, Everson, Ellen S., Young, Kevin G., Rüssmann, Holger, Krishnan, Lakshmi, Sad, Subash

Volltext

A Method to Evaluate In Vivo CD8+ T Cell Cytotoxicity in a Murine Model von Stark, Felicity C., Dudani, Renu, Agbayani, Gerard, McCluskie, Michael J.

Volltext

A comparison of the immune responses induced by antigens in three different archaeosome-based vaccine formulations von Jia, Yimei, Akache, Bassel, Deschatelets, Lise, Qian, Hui, Dudani, Renu, Harrison, Blair A., Stark, Felicity C., Chandan, Vandana, Jamshidi, Mohammad P., Krishnan, Lakshmi, McCluskie, Michael J.

Volltext

Production, purification and immunogenicity of Gag virus-like particles carrying SARS-CoV-2 components von Gashti, Anahita Bakhshizadeh, Agbayani, Gerard, Hrapovic, Sabahudin, Nassoury, Nasha, Coulombe, Nathalie, Dudani, Renu, Harrison, Blair A, Akache, Bassel, Gilbert, Rénald, Chahal, Parminder Singh

Volltext

SARS-CoV-2 spike-based virus-like particles incorporate influenza H1/N1 antigens and induce dual immunity in mice von Sanchez-Martinez, Zalma V., Alpuche-Lazcano, Sergio P., Stuible, Matthew, Akache, Bassel, Renner, Tyler M., Deschatelets, Lise, Dudani, Renu, Harrison, Blair A., McCluskie, Michael J., Hrapovic, Sabahudin, Blouin, Julie, Wang, Xinyu, Schuller, Matthew, Cui, Kai, Cho, Jae-Young, Durocher, Yves

Volltext

Intranasal administration of unadjuvanted SARS‐CoV‐2 spike antigen boosts antigen‐specific immune responses induced by parenteral protein subunit vaccine prime in mice and hamsters... von Agbayani, Gerard, Akache, Bassel, Renner, Tyler M., Tran, Anh, Stuible, Matthew, Dudani, Renu, Harrison, Blair A., Duque, Diana, Bavananthasivam, Jegarubee, Deschatelets, Lise, Hemraz, Usha D., Régnier, Sophie, Durocher, Yves, McCluskie, Michael J.

Volltext

Archaeal glycolipid adjuvanted vaccines induce strong influenza-specific immune responses through direct immunization in young and aged mice or through passive maternal immunizatio... von Stark, Felicity C., Akache, Bassel, Ponce, Amalia, Dudani, Renu, Deschatelets, Lise, Jia, Yimei, Sauvageau, Janelle, Williams, Dean, Jamshidi, Mohammad P., Agbayani, Gerard, Wachholz, Kristina, Harrison, Blair A., Li, Xuguang, Krishnan, Lakshmi, Chen, Wangxue, McCluskie, Michael J.

Volltext