Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis von Ordureau, Alban, Sarraf, Shireen A., Duda, David M., Heo, Jin-Mi, Jedrychowski, Mark P., Sviderskiy, Vladislav O., Olszewski, Jennifer L., Koerber, James T., Xie, Tiao, Beausoleil, Sean A., Wells, James A., Gygi, Steven P., Schulman, Brenda A., Harper, J. Wade

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Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy von Ordureau, Alban, Heo, Jin-Mi, Duda, David M., Paulo, Joao A., Olszewski, Jennifer L., Yanishevski, David, Rinehart, Jesse, Schulman, Brenda A., Harper, J. Wade

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Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation von Scott, Daniel C., Rhee, David Y., Duda, David M., Kelsall, Ian R., Olszewski, Jennifer L., Paulo, Joao A., de Jong, Annemieke, Ovaa, Huib, Alpi, Arno F., Harper, J. Wade, Schulman, Brenda A.

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Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface von Duda, David M., Olszewski, Jennifer L., Tron, Adriana E., Hammel, Michal, Lambert, Lester J., Waddell, M. Brett, Mittag, Tanja, DeCaprio, James A., Schulman, Brenda A.

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Structural regulation of cullin-RING ubiquitin ligase complexes von Duda, David M, Scott, Daniel C, Calabrese, Matthew F, Zimmerman, Erik S, Zheng, Ning, Schulman, Brenda A

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Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism von Duda, David M., Olszewski, Jennifer L., Schuermann, Jonathan P., Kurinov, Igor, Miller, Darcie J., Nourse, Amanda, Alpi, Arno F., Schulman, Brenda A.

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TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes von Kelsall, Ian R, Duda, David M, Olszewski, Jennifer L, Hofmann, Kay, Knebel, Axel, Langevin, Frédéric, Wood, Nicola, Wightman, Melanie, Schulman, Brenda A, Alpi, Arno F

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The Glomuvenous Malformation Protein Glomulin Binds Rbx1 and Regulates Cullin RING Ligase-Mediated Turnover of Fbw7 von Tron, Adriana E., Arai, Takehiro, Duda, David M., Kuwabara, Hiroshi, Olszewski, Jennifer L., Fujiwara, Yuko, Bahamon, Brittany N., Signoretti, Sabina, Schulman, Brenda A., DeCaprio, James A.

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Structural Studies of HHARI/UbcH7∼Ub Reveal Unique E2∼Ub Conformational Restriction by RBR RING1 von Dove, Katja K., Olszewski, Jennifer L., Martino, Luigi, Duda, David M., Wu, Xiaoli S., Miller, Darcie J., Reiter, Katherine H., Rittinger, Katrin, Schulman, Brenda A., Klevit, Rachel E.

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Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures von Kaiser, Stephen E, Mao, Kai, Taherbhoy, Asad M, Yu, Shanshan, Olszewski, Jennifer L, Duda, David M, Kurinov, Igor, Deng, Alan, Fenn, Timothy D, Klionsky, Daniel J, Schulman, Brenda A

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A Dual E3 Mechanism for Rub1 Ligation to Cdc53 von Scott, Daniel C., Monda, Julie K., Grace, Christy R.R., Duda, David M., Kriwacki, Richard W., Kurz, Thimo, Schulman, Brenda A.

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Pathogenic bacteria target NEDD8-conjugated cullins to hijack host-cell signaling pathways von Jubelin, Grégory, Taieb, Frédéric, Duda, David M, Hsu, Yun, Samba-Louaka, Ascel, Nobe, Rika, Penary, Marie, Watrin, Claude, Nougayrède, Jean-Philippe, Schulman, Brenda A, Stebbins, C Erec, Oswald, Eric

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Activity-based profiling of cullin–RING E3 networks by conformation-specific probes von Henneberg, Lukas T., Singh, Jaspal, Duda, David M., Baek, Kheewoong, Yanishevski, David, Murray, Peter J., Mann, Matthias, Sidhu, Sachdev S., Schulman, Brenda A.

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Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation von Duda, David M., Borg, Laura A., Scott, Daniel C., Hunt, Harold W., Hammel, Michal, Schulman, Brenda A.

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Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases von Zhuang, Min, Calabrese, Matthew F., Liu, Jiang, Waddell, M. Brett, Nourse, Amanda, Hammel, Michal, Miller, Darcie J., Walden, Helen, Duda, David M., Seyedin, Steven N., Hoggard, Timothy, Harper, J. Wade, White, Kevin P., Schulman, Brenda A.

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Structural Analysis of Escherichia Coli ThiF von Duda, David M., Walden, Helen, Sfondouris, John, Schulman, Brenda A.

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Quantitative Proteomics Reveal a Feedforward Model for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis von Ordureau, Alban, Sarraf, Shireen A., Duda, David M., Heo, Jin-Mi, Jedrychowski, Mark P., Sviderskiy, Vladislav O., Olszewski, Jennifer L., Koerber, James T., Xie, Tiao, Beausoleil, Sean A., Wells, James A., Gygi, Steven P., Schulman, Brenda A., Harper, J. Wade

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E2-RING Expansion of the NEDD8 Cascade Confers Specificity to Cullin Modification von Huang, Danny T., Ayrault, Olivier, Hunt, Harold W., Taherbhoy, Asad M., Duda, David M., Scott, Daniel C., Borg, Laura A., Neale, Geoffrey, Murray, Peter J., Roussel, Martine F., Schulman, Brenda A.

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Site‐directed integration of exogenous DNA into the soybean genome by LbCas12a fused to a plant viral HUH endonuclease von Nagy, Ervin D., Kuehn, Rosemarie, Wang, Dafu, Shrawat, Ashok, Duda, David M., Groat, Jeanna R., Yang, Peizhen, Beach, Steven, Zhang, Yuanji, Rymarquis, Linda, Carter, Sharina L., Gaeta, Robert T., Gilbertson, Larry A.

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Distinct Functional Domains of Ubc9 Dictate Cell Survival and Resistance to Genotoxic Stress von van Waardenburg, Robert C. A. M., Duda, David M., Lancaster, Cynthia S., Schulman, Brenda A., Bjornsti, Mary-Ann

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