The host STING pathway at the interface of cancer and immunity von Corrales, Leticia, McWhirter, Sarah M, Dubensky, Jr, Thomas W, Gajewski, Thomas F

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Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity von Corrales, Leticia, Glickman, Laura Hix, McWhirter, Sarah M., Kanne, David B., Sivick, Kelsey E., Katibah, George E., Woo, Seng-Ryong, Lemmens, Edward, Banda, Tamara, Leong, Justin J., Metchette, Ken, Dubensky, Thomas W., Gajewski, Thomas F.

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STING Pathway Activation Stimulates Potent Immunity against Acute Myeloid Leukemia von Curran, Emily, Chen, Xiufen, Corrales, Leticia, Kline, Douglas E., Dubensky, Thomas W., Duttagupta, Priyanka, Kortylewski, Marcin, Kline, Justin

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Antagonism of the STING Pathway via Activation of the AIM2 Inflammasome by Intracellular DNA von Corrales, Leticia, Woo, Seng-Ryong, Williams, Jason B, McWhirter, Sarah M, Dubensky, Jr, Thomas W, Gajewski, Thomas F

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STING-Activating Adjuvants Elicit a Th17 Immune Response and Protect against Mycobacterium tuberculosis Infection von Van Dis, Erik, Sogi, Kimberly M., Rae, Chris S., Sivick, Kelsey E., Surh, Natalie H., Leong, Meredith L., Kanne, David B., Metchette, Ken, Leong, Justin J., Bruml, Jacob R., Chen, Vivian, Heydari, Kartoosh, Cadieux, Nathalie, Evans, Tom, McWhirter, Sarah M., Dubensky, Thomas W., Portnoy, Daniel A., Stanley, Sarah A.

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A Live-Attenuated Listeria Vaccine (ANZ-100) and a Live-Attenuated Listeria Vaccine Expressing Mesothelin (CRS-207) for Advanced Cancers: Phase I Studies of Safety and Immune Induc... von LE, Dung T, BROCKSTEDT, Dirk G, GIEDLIN, Martin, LOUIS, Jana-Lynn, SUGAR, Elizabeth A, PONS, Alice, COX, Andrea L, LEVINE, Jordana, LUCK MURPHY, Aimee, ILLEI, Peter, DUBENSKY, Thomas W, EIDEN, Joseph E, NIR-PAZ, Ran, JAFFEE, Elizabeth M, LAHERU, Daniel A, HAMPL, Johannes, MATHUR, Shruti, NEMUNAITIS, John, STERMAN, Daniel H, HASSAN, Raffit, LUTZ, Eric, MOYER, Bentley

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Adjuvants for cancer vaccines von Dubensky, Thomas W, Reed, Steven G

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Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors von Baird, Jason R, Friedman, David, Cottam, Benjamin, Dubensky, Jr, Thomas W, Kanne, David B, Bambina, Shelly, Bahjat, Keith, Crittenden, Marka R, Gough, Michael J

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Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity von Sivick, Kelsey E., Desbien, Anthony L., Glickman, Laura Hix, Reiner, Gabrielle L., Corrales, Leticia, Surh, Natalie H., Hudson, Thomas E., Vu, Uyen T., Francica, Brian J., Banda, Tamara, Katibah, George E., Kanne, David B., Leong, Justin J., Metchette, Ken, Bruml, Jacob R., Ndubaku, Chudi O., McKenna, Jeffrey M., Feng, Yan, Zheng, Lianxing, Bender, Steven L., Cho, Charles Y., Leong, Meredith L., van Elsas, Andrea, Dubensky, Thomas W., McWhirter, Sarah M.

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Recombinant Listeria promotes tumor rejection by CD8⁺ T cell-dependent remodeling of the tumor microenvironment von Deng, Weiwen, Lira, Victor, Hudson, Thomas E., Lemmens, Edward E., Hanson, William G., Flores, Ruben, Barajas, Gonzalo, Katibah, George E., Desbien, Anthony L., Lauer, Peter, Leong, Meredith L., Portnoy, Daniel A., Dubensky, Thomas W.

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Listeria monocytogenes multidrug resistance transporters activate a cytosolic surveillance pathway of innate immunity von Crimmins, Gregory T, Herskovits, Anat A, Rehder, Kai, Sivick, Kelsey E, Lauer, Peter, Dubensky, Thomas W. Jr, Portnoy, Daniel A

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The VirAB ABC Transporter Is Required for VirR Regulation of Listeria monocytogenes Virulence and Resistance to Nisin von Grubaugh, Daniel, Regeimbal, James M, Ghosh, Pallab, Zhou, Yan, Lauer, Peter, Dubensky, Jr, Thomas W, Higgins, Darren E

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Comment on "The Common R71H-G230A-R293Q Human TMEM173 Is a Null Allele" von Sivick, Kelsey E, Surh, Natalie H, Desbien, Anthony L, Grewal, Eric P, Katibah, George E, McWhirter, Sarah M, Dubensky, Jr, Thomas W

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A Listeria Vaccine and Depletion of T-Regulatory Cells Activate Immunity Against Early Stage Pancreatic Intraepithelial Neoplasms and Prolong Survival of Mice von Keenan, Bridget P, Saenger, Yvonne, Kafrouni, Michel I, Leubner, Ashley, Lauer, Peter, Maitra, Anirban, Rucki, Agnieszka A, Gunderson, Andrew J, Coussens, Lisa M, Brockstedt, Dirk G, Dubensky, Thomas W, Hassan, Raffit, Armstrong, Todd D, Jaffee, Elizabeth M

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A STING Agonist Given with OX40 Receptor and PD-L1 Modulators Primes Immunity and Reduces Tumor Growth in Tolerized Mice von Foote, Jeremy B, Kok, Marleen, Leatherman, James M, Armstrong, Todd D, Marcinkowski, Bridget C, Ojalvo, Laureen S, Kanne, David B, Jaffee, Elizabeth M, Dubensky, Jr, Thomas W, Emens, Leisha A

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Combining STING-based neoantigen-targeted vaccine with checkpoint modulators enhances antitumor immunity in murine pancreatic cancer von Kinkead, Heather L, Hopkins, Alexander, Lutz, Eric, Wu, Annie A, Yarchoan, Mark, Cruz, Kayla, Woolman, Skylar, Vithayathil, Teena, Glickman, Laura H, Ndubaku, Chudi O, McWhirter, Sarah M, Dubensky, Jr, Thomas W, Armstrong, Todd D, Jaffee, Elizabeth M, Zaidi, Neeha

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Clinical Development of Listeria monocytogenes –Based Immunotherapies von Le, Dung T, Dubensky, Thomas W, Brockstedt, Dirk G

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Killed but metabolically active vaccines von Dubensky, Thomas W, Skoble, Justin, Lauer, Peter, Brockstedt, Dirk G

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Constitutive Activation of the PrfA Regulon Enhances the Potency of Vaccines Based on Live-Attenuated and Killed but Metabolically Active Listeria monocytogenes Strains von Lauer, Peter, Hanson, Bill, Lemmens, Edward E, Liu, Weiqun, Luckett, William S, Leong, Meredith L, Allen, Heather E, Skoble, Justin, Bahjat, Keith S, Freitag, Nancy E, Brockstedt, Dirk G, Dubensky, Thomas W. Jr

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Listeria-Based Cancer Vaccines That Segregate Immunogenicity from Toxicity von Brockstedt, Dirk G., Giedlin, Martin A., Leong, Meredith L., Bahjat, Keith S., Gao, Yi, Luckett, William, Liu, Weiqun, Cook, David N., Portnoy, Daniel A., Dubensky, Thomas W., Allison, James P.

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